NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound

Chemical Communications

Volumn 49, Issue 62, 2013, Pages 6944-6946

  Wedlock, Louise E ^a,b   Kilburn, Matt R ^b   Liu, Rong ^b   Shaw, Jeremy A ^b   Berners Price, Susan J ^a,b   Farrell, Nicholas P ^a,c  

^a GRIFFITH UNIVERSITY   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; TRIPLATIN TETRANITRATE; AMINE; ANTINEOPLASTIC AGENT; PLATINUM COMPLEX;

ARTICLE; CANCER CELL; CELL COMPARTMENTALIZATION; CELL TRACKING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; MASS SPECTROMETRY; MORPHOLOGY; NANO SCALE SECONDARY ION MASS SPECTROMETRY; NANOIMAGING; NUCLEOLUS; TARGET CELL; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; MCF 7 CELL LINE; NANOTECHNOLOGY; STRUCTURE ACTIVITY RELATION;

AMINES; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; NANOTECHNOLOGY; ORGANOPLATINUM COMPOUNDS; SPECTROMETRY, MASS, SECONDARY ION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84882281063     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c3cc42098a     Document Type: Article

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