메뉴 건너뛰기




Volumn 71, Issue 6, 2013, Pages 300-307

Smelling the diagnosis A review on the use of scent in diagnosing disease

Author keywords

Detection dog; Electronic nose; Odours; Scent detection; Smell

Indexed keywords

ASTHMA; BLADDER CANCER; BREAST CANCER; CHRONIC OBSTRUCTIVE LUNG DISEASE; COLORECTAL CANCER; DIABETES MELLITUS; DOG; ELECTRONIC NOSE; HUMAN; INTESTINE INFECTION; LIVER CIRRHOSIS; LUNG CANCER; LUNG INFECTION; MELANOMA; METABOLIC DISORDER; NONHUMAN; ODOR; OVARY CANCER; REVIEW; SENSITIVITY AND SPECIFICITY; SMELLING;

EID: 84882249036     PISSN: 03002977     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (102)

References (56)
  • 1
    • 0001983093 scopus 로고
    • Gas chromatographic applications in microbiology and medicine
    • New York, John Wiley and Sons
    • Mitruka BM. Gas chromatographic applications in microbiology and medicine. In: Mitruka BM, ed, Gas chromatographic applications in microbiology and medicine. New York: John Wiley and Sons; 1975; 349-74.
    • (1975) Gas Chromatographic Applications In Microbiology and Medicine , pp. 349-374
    • Mitruka, B.M.1
  • 2
    • 0024603463 scopus 로고
    • Sniffer dogs in the melanoma clinic?
    • Williams H, Pembroke A. Sniffer dogs in the melanoma clinic? Lancet. 1989;1:734.
    • (1989) Lancet , vol.1 , pp. 734
    • Williams, H.1    Pembroke, A.2
  • 3
    • 0019904401 scopus 로고
    • Analysis of discrimination mechanisms in the mammalian olfactory system using a model nose
    • Persaud K, Dodd G. Analysis of discrimination mechanisms in the mammalian olfactory system using a model nose. Nature. 1982;299:352-5.
    • (1982) Nature , vol.299 , pp. 352-355
    • Persaud, K.1    Dodd, G.2
  • 4
    • 68549101842 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration
    • Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009;339:b2700.
    • (2009) BMJ , vol.339
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3
  • 5
    • 84860323726 scopus 로고    scopus 로고
    • Canine scent detection in the diagnosis of lung cancer: Revisiting a puzzling phenomenon
    • Ehmann R, Boedeker E, Friedrich U, et al. Canine scent detection in the diagnosis of lung cancer: revisiting a puzzling phenomenon. Eur Respir J. 2012;39:669-76.
    • (2012) Eur Respir J , vol.39 , pp. 669-676
    • Ehmann, R.1    Boedeker, E.2    Friedrich, U.3
  • 6
    • 0015131404 scopus 로고
    • Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography
    • Pauling L, Robinson AB, Teranishi R, Cary P. Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography. Proc Natl Acad Sci U S A. 1971;68:2374-6.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 2374-2376
    • Pauling, L.1    Robinson, A.B.2    Teranishi, R.3    Cary, P.4
  • 8
    • 70449378196 scopus 로고    scopus 로고
    • Noninvasive detection of lung cancer by analysis of exhaled breath
    • Bajtarevic A, Ager C, Pienz M, et al. Noninvasive detection of lung cancer by analysis of exhaled breath. BMC Cancer. 2009;9:348.
    • (2009) BMC Cancer , vol.9 , pp. 348
    • Bajtarevic, A.1    Ager, C.2    Pienz, M.3
  • 9
    • 77950457591 scopus 로고    scopus 로고
    • An investigation on electronic nose diagnosis of lung cancer
    • D'Amico A, Pennazza G, Santonico M, et al. An investigation on electronic nose diagnosis of lung cancer. Lung Cancer. 2010;68:170-6.
    • (2010) Lung Cancer , vol.68 , pp. 170-176
    • D'Amico, A.1    Pennazza, G.2    Santonico, M.3
  • 10
    • 0037756779 scopus 로고    scopus 로고
    • Lung cancer identification by the analysis of breath by means of an array of non-selective gas sensors
    • Di Natale C, Macagnano A, Martinelli E, et al. Lung cancer identification by the analysis of breath by means of an array of non-selective gas sensors. Biosens Bioelectron. 2003;18:1209-18.
    • (2003) Biosens Bioelectron , vol.18 , pp. 1209-1218
    • Di Natale, C.1    Macagnano, A.2    Martinelli, E.3
  • 11
    • 21144450472 scopus 로고    scopus 로고
    • Detection of lung cancer by sensor array analyses of exhaled breath
    • Machado RF, Laskowski D, Deffenderfer O, et al. Detection of lung cancer by sensor array analyses of exhaled breath. Am J Respir Crit Care Med. 2005;171:1286-91.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1286-1291
    • Machado, R.F.1    Laskowski, D.2    Deffenderfer, O.3
  • 12
    • 63249102023 scopus 로고    scopus 로고
    • An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD
    • Dragonieri S, Annema JT, Schot R, et al. An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD. Lung Cancer. 2009;64:166-70.
    • (2009) Lung Cancer , vol.64 , pp. 166-170
    • Dragonieri, S.1    Annema, J.T.2    Schot, R.3
  • 13
    • 78549290706 scopus 로고    scopus 로고
    • Characteristic odour in the blood reveals ovarian carcinoma
    • Horvath G, Andersson H, Paulsson G. Characteristic odour in the blood reveals ovarian carcinoma. BMC Cancer. 2010;10:643.
    • (2010) BMC Cancer , vol.10 , pp. 643
    • Horvath, G.1    Andersson, H.2    Paulsson, G.3
  • 14
    • 77957261390 scopus 로고    scopus 로고
    • Different volatile signals emitted by human ovarian carcinoma and healthy tissue
    • Horvath G, Chilo J, Lindblad T. Different volatile signals emitted by human ovarian carcinoma and healthy tissue. Future Oncol. 2010;6:1043-9.
    • (2010) Future Oncol , vol.6 , pp. 1043-1049
    • Horvath, G.1    Chilo, J.2    Lindblad, T.3
  • 15
    • 0035467993 scopus 로고    scopus 로고
    • Gloabal cancer statistics in the year 2000
    • Parkin DM. Gloabal cancer statistics in the year 2000. Lancet Oncology. 2001;2:533-43.
    • (2001) Lancet Oncology , vol.2 , pp. 533-543
    • Parkin, D.M.1
  • 16
    • 0037736535 scopus 로고    scopus 로고
    • Volatile markers of breast cancer in the breath
    • Phillips M, Cataneo RN, Ditkoff BA, et al. Volatile markers of breast cancer in the breath. Breast J. 2003;9:184-91.
    • (2003) Breast J , vol.9 , pp. 184-191
    • Phillips, M.1    Cataneo, R.N.2    Ditkoff, B.A.3
  • 19
    • 4744340118 scopus 로고    scopus 로고
    • Olfactory detection of human bladder cancer by dogs: Proof of principle study
    • Willis CM, Church SM, Guest CM, et al. Olfactory detection of human bladder cancer by dogs: proof of principle study. BMJ. 2004;329:712.
    • (2004) BMJ , vol.329 , pp. 712
    • Willis, C.M.1    Church, S.M.2    Guest, C.M.3
  • 20
    • 41449099877 scopus 로고    scopus 로고
    • A preliminary study on the possibility to diagnose urinary tract cancers by an electronic nose
    • Bernabei M, Pennazza G, Santortico M, et al. A preliminary study on the possibility to diagnose urinary tract cancers by an electronic nose. Sens Actuat B. 2008;131:1-4.
    • (2008) Sens Actuat B , vol.131 , pp. 1-4
    • Bernabei, M.1    Pennazza, G.2    Santortico, M.3
  • 21
    • 79955858222 scopus 로고    scopus 로고
    • Colorectal cancer screening with odour material by canine scent detection
    • Sonoda H, Kohnoe S, Yamazato T, et al. Colorectal cancer screening with odour material by canine scent detection. Gut. 2011;60:814-9.
    • (2011) Gut , vol.60 , pp. 814-819
    • Sonoda, H.1    Kohnoe, S.2    Yamazato, T.3
  • 22
    • 0030466190 scopus 로고    scopus 로고
    • Comparison of three faecal occult blood tests in the detection of colorectal neoplasia
    • Hope RL, Chu G, Hope AH, Newcombe RG, Gillespie PE, Williams SJ. Comparison of three faecal occult blood tests in the detection of colorectal neoplasia. Gut. 1996;39:722-5.
    • (1996) Gut , vol.39 , pp. 722-725
    • Hope, R.L.1    Chu, G.2    Hope, A.H.3    Newcombe, R.G.4    Gillespie, P.E.5    Williams, S.J.6
  • 23
    • 3242728313 scopus 로고    scopus 로고
    • Results of the first round of a demonstration pilot of screening for colorectal cancer in the United Kingdom
    • UK colorectal cancer screening pilot group
    • UK colorectal cancer screening pilot group. Results of the first round of a demonstration pilot of screening for colorectal cancer in the United Kingdom. BMJ. 2004;329:133.
    • (2004) BMJ , vol.329 , pp. 133
  • 24
    • 0034735826 scopus 로고    scopus 로고
    • The effect of fecal occult-blood screening on the incidence of colorectal cancer
    • Mandel JS, Church TR, Bond JH, et al. The effect of fecal occult-blood screening on the incidence of colorectal cancer. N Engl J Med. 2000;343:1603-7.
    • (2000) N Engl J Med , vol.343 , pp. 1603-1607
    • Mandel, J.S.1    Church, T.R.2    Bond, J.H.3
  • 25
    • 77955515058 scopus 로고    scopus 로고
    • Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors
    • Peng G, Hakim M, Broza YY, et al. Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors. Br J Cancer. 2010;103:542-51.
    • (2010) Br J Cancer , vol.103 , pp. 542-551
    • Peng, G.1    Hakim, M.2    Broza, Y.Y.3
  • 27
    • 42449094957 scopus 로고    scopus 로고
    • Identification of melanoma with a gas sensor array
    • D'Amico A, Bono R, Pennazza G, et al. Identification of melanoma with a gas sensor array. Skin Res Technol. 2008;14:226-36.
    • (2008) Skin Res Technol , vol.14 , pp. 226-236
    • D'Amico, A.1    Bono, R.2    Pennazza, G.3
  • 28
    • 2342617481 scopus 로고
    • The early history of gas gangrene
    • Kellet CE. The early history of gas gangrene. Ann Med Hist. 1939;1:452-9
    • (1939) Ann Med Hist , vol.1 , pp. 452-459
    • Kellet, C.E.1
  • 30
    • 0034058883 scopus 로고    scopus 로고
    • American Thoracic Society
    • Diagnostic Standards and Classification of Tuberculosis in Adults and Children
    • Diagnostic Standards and Classification of Tuberculosis in Adults and Children. American Thoracic Society. Am J Respir Crit Care Med. 2000;161:1376-95.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1376-1395
  • 31
    • 79958724329 scopus 로고    scopus 로고
    • Using giant African pouched rats to detect land mines: Another victory for operant conditioning
    • Poling A, Weetjens B, Cox C, Beyene N, Sully A. Using giant African pouched rats to detect land mines: Another victory for operant conditioning. J Appl Behav Anal. 2011;44:351-5.
    • (2011) J Appl Behav Anal , vol.44 , pp. 351-355
    • Poling, A.1    Weetjens, B.2    Cox, C.3    Beyene, N.4    Sully, A.5
  • 32
    • 84856198907 scopus 로고    scopus 로고
    • Diagnosis of tuberculosis by trained African giant pouched rats and confounding impact of pathogens and microflora of the respiratory tract
    • Mgode GF, Weetjens BJ, Nawrath T, et al. Diagnosis of tuberculosis by trained African giant pouched rats and confounding impact of pathogens and microflora of the respiratory tract. J Clin Microbiol. 2012;50:274-80.
    • (2012) J Clin Microbiol , vol.50 , pp. 274-280
    • Mgode, G.F.1    Weetjens, B.J.2    Nawrath, T.3
  • 33
    • 84867334957 scopus 로고    scopus 로고
    • Pouched Rats' Detection of Tuberculosis in Human Sputum: Comparison to Culturing and Polymerase Chain Reaction
    • Mahoney A, Weetjens BJ, Cox C, et al. Pouched Rats' Detection of Tuberculosis in Human Sputum: Comparison to Culturing and Polymerase Chain Reaction. Tuberc Res Treat. 2012;2012:716-989.
    • (2012) Tuberc Res Treat , vol.2012 , pp. 716-989
    • Mahoney, A.1    Weetjens, B.J.2    Cox, C.3
  • 34
    • 79960255842 scopus 로고    scopus 로고
    • Honeybees Apis mellifera can detect the scent of Mycobacterium tuberculosis
    • Suckling DM, Sagar RL. Honeybees Apis mellifera can detect the scent of Mycobacterium tuberculosis. Tuberculosis. 2011;91:327-8.
    • (2011) Tuberculosis , vol.91 , pp. 327-328
    • Suckling, D.M.1    Sagar, R.L.2
  • 35
    • 77950691260 scopus 로고    scopus 로고
    • Breath biomarkers of active pulmonary tuberculosis
    • Phillips M, Basa-Dalay V, Bothamley G, et al. Breath biomarkers of active pulmonary tuberculosis. Tuberculosis. 2010;90:145-51.
    • (2010) Tuberculosis , vol.90 , pp. 145-151
    • Phillips, M.1    Basa-Dalay, V.2    Bothamley, G.3
  • 36
    • 79955946752 scopus 로고    scopus 로고
    • Volatile biomarkers of Pseudomonas aeruginosa in cystic fibrosis and noncystic fibrosis bronchiectasis
    • Savelev SU, Perry JD, Bourke SJ, et al. Volatile biomarkers of Pseudomonas aeruginosa in cystic fibrosis and noncystic fibrosis bronchiectasis. Lett Appl Microbiol. 2011;52:610-3.
    • (2011) Lett Appl Microbiol , vol.52 , pp. 610-613
    • Savelev, S.U.1    Perry, J.D.2    Bourke, S.J.3
  • 37
    • 0023234557 scopus 로고
    • Diagnosis of rotavirus gastroenteritis by smell
    • Poulton J, Tarlow MJ. Diagnosis of rotavirus gastroenteritis by smell. Arch Dis Child. 1987;62:851-2.
    • (1987) Arch Dis Child , vol.62 , pp. 851-852
    • Poulton, J.1    Tarlow, M.J.2
  • 38
    • 33947491541 scopus 로고    scopus 로고
    • Does the nose know? The odiferous diagnosis of Clostridium difficile-associated diarrhea
    • Burdette SD, Bernstein JM. Does the nose know? The odiferous diagnosis of Clostridium difficile-associated diarrhea. Clin Infect Dis. 2007;44:1142.
    • (2007) Clin Infect Dis , vol.44 , pp. 1142
    • Burdette, S.D.1    Bernstein, J.M.2
  • 39
    • 84872067731 scopus 로고    scopus 로고
    • Using a dog's superior olfactory sensitivity to identify Clostridium difficile in stools and patients: Proof of principle study
    • Bomers MK, van Agtmael MA, Luik H, van Veen MC, Vandenbroucke-Grauls CMJE, Smulders YM. Using a dog's superior olfactory sensitivity to identify Clostridium difficile in stools and patients: proof of principle study. BMJ. 2012;345:e7396.
    • (2012) BMJ , vol.345
    • Bomers, M.K.1    van Agtmael, M.A.2    Luik, H.3    van Veen, M.C.4    Vandenbroucke-Grauls, C.M.J.E.5    Smulders, Y.M.6
  • 40
    • 34249816158 scopus 로고    scopus 로고
    • Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease
    • Garner CE, Smith S, Costello BD, et al. Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease. FASEB J. 2007;21:1675-88.
    • (2007) FASEB J , vol.21 , pp. 1675-1688
    • Garner, C.E.1    Smith, S.2    Costello, B.D.3
  • 41
    • 0034302704 scopus 로고    scopus 로고
    • An intelligent rapid odour recognition model in discrimination of Helicobacter pylori and other gastroesophageal isolates in vitro
    • Pavlou AK, Magan N, Sharp D, Brown J, Barr H, Turner AP. An intelligent rapid odour recognition model in discrimination of Helicobacter pylori and other gastroesophageal isolates in vitro. Biosens Bioelectron. 2000;15:333-42.
    • (2000) Biosens Bioelectron , vol.15 , pp. 333-342
    • Pavlou, A.K.1    Magan, N.2    Sharp, D.3    Brown, J.4    Barr, H.5    Turner, A.P.6
  • 42
    • 0034707221 scopus 로고    scopus 로고
    • Non-invasive detection of hypoglycaemia using a novel, fully biocompatible and patient friendly alarm system
    • Chen M, Daly M, Williams N, Williams S, Williams C, Williams G. Non-invasive detection of hypoglycaemia using a novel, fully biocompatible and patient friendly alarm system. BMJ. 2000;321:1565-6.
    • (2000) BMJ , vol.321 , pp. 1565-1566
    • Chen, M.1    Daly, M.2    Williams, N.3    Williams, S.4    Williams, C.5    Williams, G.6
  • 43
    • 0036748297 scopus 로고    scopus 로고
    • Effect of trained Seizure Alert Dogs on frequency of tonic-clonic seizures
    • Strong V, Brown S, Huyton M, Coyle H. Effect of trained Seizure Alert Dogs on frequency of tonic-clonic seizures. Seizure. 2002;11:402-5.
    • (2002) Seizure , vol.11 , pp. 402-405
    • Strong, V.1    Brown, S.2    Huyton, M.3    Coyle, H.4
  • 44
    • 0035102725 scopus 로고    scopus 로고
    • The use of seizure-alert dogs
    • Brown SW, Strong V. The use of seizure-alert dogs. Seizure. 2001;10:39-41.
    • (2001) Seizure , vol.10 , pp. 39-41
    • Brown, S.W.1    Strong, V.2
  • 46
    • 2442512205 scopus 로고    scopus 로고
    • Increased breath biomarkers of oxidative stress in diabetes mellitus
    • Phillips M, Cataneo RN, Cheema T, Greenberg J. Increased breath biomarkers of oxidative stress in diabetes mellitus. Clin Chim Acta. 2004;344:189-94.
    • (2004) Clin Chim Acta , vol.344 , pp. 189-194
    • Phillips, M.1    Cataneo, R.N.2    Cheema, T.3    Greenberg, J.4
  • 47
    • 0014769163 scopus 로고
    • Volatile fatty acids in the breath of patients with cirrhosis of the liver
    • Chen S, Mahadevan V, Zieve L. Volatile fatty acids in the breath of patients with cirrhosis of the liver. J Lab Clin Med. 1970;75:622-7.
    • (1970) J Lab Clin Med , vol.75 , pp. 622-627
    • Chen, S.1    Mahadevan, V.2    Zieve, L.3
  • 49
    • 35148827504 scopus 로고    scopus 로고
    • An electronic nose in the discrimination of patients with asthma and controls
    • Dragonieri S, Schot R, Mertens BJA, et al. An electronic nose in the discrimination of patients with asthma and controls. J Allergy Clin Immunol. 2007;120:856-62.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 856-862
    • Dragonieri, S.1    Schot, R.2    Mertens, B.J.A.3
  • 50
    • 80052969558 scopus 로고    scopus 로고
    • External validation of exhaled breath profiling using an electronic nose in the discrimination of asthma with fixed airways obstruction and chronic obstructive pulmonary disease
    • Fens N, Roldaan AC, van der Schee MP, et al. External validation of exhaled breath profiling using an electronic nose in the discrimination of asthma with fixed airways obstruction and chronic obstructive pulmonary disease. Clin Exp Allergy. 2011;41:1371-8.
    • (2011) Clin Exp Allergy , vol.41 , pp. 1371-1378
    • Fens, N.1    Roldaan, A.C.2    van der Schee, M.P.3
  • 51
    • 82555189254 scopus 로고    scopus 로고
    • Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD
    • Fens N, De Nijs SB, Peters S, et al. Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD. Eur Respir J. 2011;38:1301-9.
    • (2011) Eur Respir J , vol.38 , pp. 1301-1309
    • Fens, N.1    de Nijs, S.B.2    Peters, S.3
  • 52
    • 0027430206 scopus 로고
    • Increased pentane and carbon disulfide in the breath of patients with schizophrenia
    • Phillips M, Sabas M, Greenberg J. Increased pentane and carbon disulfide in the breath of patients with schizophrenia. J Clin Pathol. 1993;46:861-4.
    • (1993) J Clin Pathol , vol.46 , pp. 861-864
    • Phillips, M.1    Sabas, M.2    Greenberg, J.3
  • 54
    • 0030947078 scopus 로고    scopus 로고
    • Analysis of medication off-odors using an electronic nose
    • Schiffman SS, Kermani BG, Nagle HT. Analysis of medication off-odors using an electronic nose. Chem Senses. 1997;22:119-28.
    • (1997) Chem Senses , vol.22 , pp. 119-128
    • Schiffman, S.S.1    Kermani, B.G.2    Nagle, H.T.3
  • 55
    • 58949103489 scopus 로고    scopus 로고
    • Iowa State University, Accessed at Air Quality and Animal Agriculture Web page
    • The science of smell Part 1: Odor perception and physiological response. Iowa State University. 2004. Accessed at Air Quality and Animal Agriculture Web page: http://www.extension.iastate.edu/airquality.
    • (2004) The Science of Smell Part 1: Odor Perception and Physiological Response
  • 56
    • 0034646331 scopus 로고    scopus 로고
    • The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates
    • Rouquier S, Blancher A, Giorgi D. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. Proc Natl Acad Sci U S A. 2000;14:2870-4.
    • (2000) Proc Natl Acad Sci U S A , vol.14 , pp. 2870-2874
    • Rouquier, S.1    Blancher, A.2    Giorgi, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.