Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein

Journal of the American Chemical Society

Volumn 135, Issue 32, 2013, Pages 11929-11934

  Sotomayor Pérez, Ana Cristina ^a   Subrini, Orso ^a   Hessel, Audrey ^a   Ladant, Daniel ^a   Chenal, Alexandre ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL EQUILIBRIUMS; GRAM-NEGATIVE BACTERIA; MACROMOLECULAR CROWDING; MOLECULAR CROWDING; POWER-LAW DEPENDENCES; STABLE STRUCTURES; STRUCTURAL CONTENT; TEMPERATURE INCREASE;

CALCIUM; CHAINS; CONFORMATIONS; MACHINERY; MACROMOLECULES; MELTING POINT; PHYSIOLOGY;

PROTEINS;

CALCIUM; NONAPEPTIDE; PROTEIN; REPEAT IN TOXIN PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; ENTHALPY; GRAM NEGATIVE BACTERIUM; MOLECULAR BIOLOGY; MOLECULAR CROWDING; NONHUMAN; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECRETION; TEMPERATURE; TYPE I SECRETION SYSTEM;

ADENYLATE CYCLASE TOXIN; BORDETELLA PERTUSSIS; CALCIUM; FICOLL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; WHOOPING COUGH;

EID: 84882248932     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja404790f     Document Type: Article

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