C3orf58, a novel paracrine protein, stimulates cardiomyocyte cell-cycle progression through the PI3K-AKT-CDK7 pathway

Circulation Research

Volumn 113, Issue 4, 2013, Pages 372-380

  Beigi, Farideh ^a   Schmeckpeper, Jeffrey ^a   Pow Anpongkul, Pete ^a   Payne, James Alan ^a   Zhang, Lunan ^a   Zhang, Zhiping ^a   Huang, Jing ^a   Mirotsou, Maria ^a   Dzau, Victor J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

cardiac; myocytes; paracrine; proliferation; regeneration

Indexed keywords

BROXURIDINE; CYCLIN DEPENDENT KINASE 7; GLYCOGEN SYNTHASE KINASE 3BETA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C3ORF58; PROTEIN KINASE B; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL DIVISION; CELL PROLIFERATION; CELL REGENERATION; CELL STIMULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINESIS; DNA SYNTHESIS; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENE SILENCING; HEART MUSCLE CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VIVO STUDY; MITOSIS; MOUSE; NEWBORN; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

MYOCYTES, CARDIAC; PARACRINE; PROLIFERATION; REGENERATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASES; DNA; HEART; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; MYOCYTES, CARDIAC; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECOMBINANT PROTEINS; REGENERATION; SIGNAL TRANSDUCTION;

EID: 84881667960     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301075     Document Type: Article

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