Independent associations of low 25 hydroxy vitamin D and high parathyroid hormonal levels with nonalcoholic fatty liver disease in Asian Indians residing in north India

Atherosclerosis

Volumn 230, Issue 1, 2013, Pages 157-163

  Bhatt, Surya Prakash ^a,b,d   Nigam, Priyanka ^a   Misra, Anoop ^a,c   Guleria, Randeep ^b   Qadar Pasha, M A ^d  

^a Diabetic Foundation ^*  (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c Fortis CDOC Center of Excellence for Diabetes   (India)

^d NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Asian Indians; Metabolic syndrome; Non alcoholic fatty liver disease; Parathyroid hormone; Serum 25 hydroxy vitamin D

Indexed keywords

ALANINE AMINOTRANSFERASE; CALCIFEDIOL; CALCIUM; CHOLESTEROL; INSULIN; PARATHYROID HORMONE; TRIACYLGLYCEROL;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASIAN; BODY COMPOSITION; BODY FAT; BONE DENSITY; CALCIUM BLOOD LEVEL; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HOMEOSTASIS; HUMAN; INDIA; INSULIN RESISTANCE; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; VITAMIN BLOOD LEVEL; WAIST CIRCUMFERENCE;

ASIAN INDIANS; METABOLIC SYNDROME; NON-ALCOHOLIC FATTY LIVER DISEASE; PARATHYROID HORMONE; SERUM 25 HYDROXY VITAMIN D;

ABSORPTIOMETRY, PHOTON; ADULT; ANTHROPOMETRY; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD PRESSURE; BODY COMPOSITION; BODY MASS INDEX; BONE DENSITY; CALCIUM; CASE-CONTROL STUDIES; FATTY LIVER; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INDIA; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PARATHYROID HORMONE; TRIGLYCERIDES; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84881630568     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2013.07.006     Document Type: Article

References (39)

1. Tsochatzis E.A., Manolakopoulos S., Papatheodoridis G.V., Archimandritis A.J. Insulin resistance and metabolic syndrome in chronic liver diseases: old entities with new implications. Scand J Gastroenterol 2009, 44(1):6-14.
2. Mohanty S.R., Troy T.N., Huo D., O'Brien B.L., Jensen D.M., Hart J. Influence of ethnicity on histological differences in non-alcoholic fatty liver disease. JHepatol 2009, 50(4):797-804.
3. Bajaj S., Nigam P., Luthra K., Pandey R.M., Kondal D., Bhatt S.P., et al. Acase-control study on insulin resistance, metabolic co-variates & prediction score in non-alcoholic fatty liver disease. Indian J Med Res 2009, 129:285-292.
4. Mohan V., Farooq S., Deepa M., Ravikumar R., Pitchumoni C.S. Prevalence of non-alcoholic fatty liver disease in urban south Indians in relation to different grades of glucose intolerance and metabolic syndrome. Diabetes Res Clin Pract 2009, 84(1):84-91.
5. Velluz G. Amiard organic chemistry-equilibrium reaction between précalciférol and calciferol. (The organic chemicalequilibrium of the reaction between precalciferol and calciferol.). CRAssoc Anat 1949, 228:853-855.
6. Reis J.P., von Mühlen D., Miller E.R. Relation of 25-hydroxy vitamin D and parathyroid hormone levels with metabolic syndrome among US adults. Eur J Endocrinol 2008, 159(1):41-48.
7. Chiu K.C., Chiu A., Go V., Saad M.F. Hypovitaminosis D is associated with insulin resistance and β cell dysfunction. Am J Clin Nutr 2004, 79(5):820-825.
8. Ginde A.A., Liu M.C., Camargo C.A. Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004. Arch Intern Med 2009, 169(6):626-632.
9. Chiu K.C., Chuang L.M., Lee N.P., Ryu J.M., McGullam J.L., Tsai G.P., et al. Insulin sensitivity is inversely correlated with plasma intact parathyroid hormone level. Metabolism 2000, 49:1501-1505.
10. Jorde R., Svartberg J., Sundsfjord J. Serum PTH as a predictor of increase in systolic blood pressure in men. JHypertens 2005, 2005:639-1644.
11. Rejnmark L., Vestergaard P., Brot C., Mosekilde L. Parathyroid response to vitamin D insufficiency: relations to bone, body composition and to lifestyle characteristics. Clin Endocrinol 2008, 69:29-35.
12. Sachan A., Gupta R., Das V., Agarwal A., Awasthi P.K., Bhatia V. High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India. Am J Clin Nutr 2005, 81:1060-1064.
13. Harinarayan C.V. Prevalence of vitamin D deficiency in postmenopausal south Indian women. Osteoporos Int 2005, 16:397-402.
14. McCarty M.F. Poor vitamin D status may contribute to high risk for insulin resistance, obesity, and cardiovascular disease in Asian Indians. Med Hypotheses 2009, 72(6):647-651.
15. Tam K.M., Wu J.S. Ultrasonographic diagnosis of fatty liver. Taiwan Yi Xue Hui Za Zhi 1986, 85:45-53.
16. Dudeja V., Misra A., Pandey R.M., Devina G., Kumar G., Vikram N.K. BMI does not accurately predict overweight in Asian Indians in Northern India. Br J Nutr 2001, 86:105-112.
17. Misra A., Chowbey P., Makkar B.M., Vikram N.K., Wasir J.S., Chadha D., et al. Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management. JAssoc Physicians India 2009, 57:163-170.
18. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003, 26:S5-S20. Expert Committee on the diagnosis and classification of Diabetes Mellitus.
19. Lambert M., Paradis G., O'Loughlin J., Delvin E.E., Hanley J.A., Levy E. Insulin resistance syndrome in a representative sample of children and adolescents from Qubec, Canada. Int J Obes Relat Metab Disord 2004, 28:833-841.
20. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
21. Goel K., Gupta N., Misra A., Poddar P., Mohan R. Predictive equations for body fat and abdominal fat with DXA and MRI as reference in Asian Indians. Obes (Silver Spring) 2008, 16(2):451-456.
22. Majumdar V., Nagaraja D., Christopher R. Vitamin D status and metabolic syndrome in Asian Indians. Int J Obes (Lond) 2010, 9.
23. Subramanian A., Nigam P., Misra A., Pandey R.M., Mathu M., Gupta R. Savior vitamin D deficiency in patients with type two diabetes mellitus in north India. Diabetes Manage 2011, 1(5).
24. Targher G., Bertolini L., Scala L., Cigolini M., Zenari L., Falezza G., et al. Associations between serum 25-hydroxy vitamin D3 concentrations and liver histology in patients with non-alcoholic fatty liver disease. Nutr Metab Cardiovasc Dis 2007, 17:517-524.
25. Barchetta I., Angelico F., Del Ben M., Baroni M.G., Pozzilli P., Morini S., et al. Strong association between nonalcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes. BMC Med 2011 Jul 12, 9:85.
26. Cheng S., Massaro J.M., Fox C.S., Larson M.G., Keyes M.J., McCabe E.L., et al. Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study. Diabetes 2010, 59(1):242-248.
27. Goel K., Misra A., Vikram N.K., Poddar P., Gupta N., et al. Subcutaneous abdominal adipose tissue is associated with the metabolic syndrome in Asian Indians independent of intra-abdominal and total body fat. Heart 2010, 96:579-583.
28. Alvarez Jessica A., Ashraf Ambika Role of vitamin D in insulin secretion and insulin sensitivity for glucose homeostasis. Int J Endocrinol 2010, 2010:351385.
29. Calle C., Maestro B., García-Arencibia M. Genomic actions of 1,25-dihydroxyvitamin D3 on insulin receptor gene expression, insulin receptor number and insulin activity in the kidney, liver and adipose tissue of streptozotocin-induced diabetic rats. BMC Mol Biol 2008, 18(9):65.
30. Pittas A.G., Harris S.S., Stark P.C., Dawson-Hughes B. The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in non-diabetic adults. Diabetes Care 2007, 30(4):980-986.
31. Roth C.L., Elfers C.T., Figlewicz D.P., Melhorn S.J., Morton G.J., Hoofnagle A., et al. Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and toll-like receptor activation. Hepatology 2012, 55(4):1103-1111.
32. Garcíade León Mdel C., Montfort I., Tello Montes E., López Vancell R., Olivos García A., González Canto A., et al. Hepatocyte production of modulators of extracellular liver matrix in normal and cirrhotic rat liver. Exp Mol Pathol 2006, 80(1):97-108.
33. Kayaniyil S., Vieth R., Harris S.B., Retnakaran R., Knight J.A., Gerstein H.C., et al. Association of 25(OH)D and PTH with metabolic syndrome and its traditional and nontraditional components. JClin Endocrinol Metab 2011, 96(1):168-175.
34. Abate N., Chandalia M., Snell P.G., Grundy S.M. Adipose tissue metabolites and insulin resistance in nondiabetic Asian Indian men. JClin Endocrinol Metab 2004 Jun, 89(6):2750-2755.
35. Bhatt S.P., Nigam P., Misra A., Guleria R., Luthra K., Pandey R.M., et al. Association of peroxisome proliferator activated receptor-γ gene with nonalcoholic fatty liver disease in Asian Indians residing in north India. Gene 2013, 1, 512(1):143-147.
36. Petersen K.F., Dufour S., Befroy D., Garcia R., Shulman G.I. Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian- Indian men. Proc Natl Acad Sci U S A 2006, 103:18273-18277.
37. Reis J.P., von Muhlen D., Kritz-Silverstein D., Wingard D.L., Barrett-Connor E. Vitamin D, parathyroid hormone levels, and the prevalence of metabolic syndrome in community-dwelling older adults. Diabetes Care 2007, 30(6):1549-1555.
38. McGill A.T., Stewart J.M., Lithander F.E., Strik C.M., Poppitt S.D. Relationships of low serum vitamin D3 with anthropometry and markers of the metabolic syndrome and diabetes in overweight and obesity. Nutr J 2008, 7:4.
39. Soares M.J., Ping-Delfos W.C., Sherriff J.L., Nezhad D.H., Cummings N.K., Zhao Y. Vitamin D and parathyroid hormone in insulin resistance of abdominal obesity: cause or effect?. Eur J Clin Nutr 2011, 65(12):1348-1352.