Unusual coexistence of opportunistic lung infections in a human immunodeficiency virus positive patient suffering from persistent pneumocystis jirovecii pneumonia: A case report

Revista Portuguesa de Pneumologia

Volumn 19, Issue 3, 2013, Pages 129-133

  Ponces Bento, D ^a   Esteves, F ^b   Matos, O ^b   Miranda, A C ^a   Ventura, F ^a   Araujo C ^a   Mansinho, K ^a  

^a HOSPITAL EGAS MONIZ   (Portugal)

^b INSTITUTO DE HIGIENE E MEDICINA TROPICAL   (Portugal)

Author keywords

Human immunodeficiency virus; Opportunistic lung infections; Pneumocystis jirovecii pneumonia

Indexed keywords

ANTIINFECTIVE AGENT;

ADULT; ANTIMICROBIAL THERAPY; ARTICLE; CASE REPORT; CONVALESCENCE; CYTOMEGALOVIRUS INFECTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; INTERSTITIAL PNEUMONIA; INVASIVE ASPERGILLOSIS; LABORATORY TEST; LUNG INFECTION; MYCOBACTERIOSIS; MYCOBACTERIUM XENOPEI; OPPORTUNISTIC INFECTION; PNEUMOCYSTIS PNEUMONIA;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; HIV SEROPOSITIVITY; HUMANS; MALE; MIDDLE AGED; PNEUMOCYSTIS JIROVECII; PNEUMONIA, PNEUMOCYSTIS;

EID: 84881609605     PISSN: 08732159     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rppneu.2013.01.005     Document Type: Article

References (19)

1. Huang L., Cattamanchi A., Davis J.L., den Boon S., Kovacs J., Meshnick S., et al. HIV-Associated Pneumocystis pneumonia. Proc Am Thorac Soc 2011, 8:294-300.
2. Madhi S.A., Cutland C., Ismail K., O'Reilly C., Mancha A., Klugman K.P. Ineffectiveness of trimethoprim-sulfamethoxazole prophylaxis and the importance of bacterial and viral coinfections in African children with Pneumocystis carinii pneumonia. Clin Infect Dis 2002, 35:1120-1126.
3. Addrizzo-Harris D.J., Harkin T.J., McGuinness G., Naidich D.P., Rom W.N. Pulmonary Aspergilloma and AIDS: A comparison of HIV-infected and HIV-negative individuals. Chest 1997, 111:612-618.
4. Mariñosa M., Soler A., Nogués X., Pedro-Botet J. Pulmonary coinfection by Pneumocystis carinii and Aspergillus fumigatus in a seronegative arthritis patient treated with low-dose methotrexate. Clin Rheumatol 2004, 23:555-556.
5. Kaira K., Shimoyama Y., Takahashi Y., Iida T., Yanigitani N., Sunaga N., et al. Coinfection of invasive pulmonary Aspergillosis and Pneumocystis jiroveci pneumonia in a non-HIV patient. Acta Med Okayama 2007, 61:235-238.
6. Camuset J., Nunes H., Dombret M.C., Bergeron A., Henno P., Philippe B., et al. Treatment of chronic pulmonary aspergillosis by voriconazole in nonimmunocompromised patients. Chest 2007, 131:1435-1441.
7. Simpson-Haidaris P.J., Courtney M.A., Wright T.W., Goss R., Harmsen A., Gigliotti F. Induction of fibrinogen expression in the lung epithelium during Pneumocystis carinii pneumonia. Infect Immun 1998, 66:4431-4439.
8. Dagenais T.R., Keller N.P. Pathogenesis of Aspergillus fumigatus in invasive Aspergillosis. Clin Microbiol Rev 2009, 22:447-465.
9. Moorman A.C., Von Bargen J.C., Palella F.J., Holmberg S.D. Pneumocystis carinii pneumonia incidence and chemoprophylaxis failure in ambulatory HIV-infected patients. HIV Outpatient Study (HOPS) Investigators. J Acquir Immune Defic Syndr Hum Retrovirol 1998, 19:182-188.
10. Crothers K., Beard C.B., Turner J., Groner G., Fox M., Morris A., et al. Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations. AIDS 2005, 19:801-805.
11. Matos O., Esteves F. Epidemiology and clinical relevance of Pneumocystis jirovecii Frenkel, 1976 dihydropteroate synthase gene mutations. Parasite 2010, 17:219-232.
12. Kazanjian P., Armstrong W., Hossler P.A., Lee C.H., Huang L., Beard C.B., et al. Pneumocystis carinii cytochrome b mutations are associated with atovaquone exposure in patients with AIDS. J Infect Dis 2001, 183:819-822.
13. Esteves F., Gaspar J., Tavares A., Moser I., Antunes F., Mansinho K., et al. Population structure of Pneumocystis jirovecii isolated from immunodeficiency virus-positive patients. Infect Genet Evol 2010, 10:192-199.
14. Esteves F., Gaspar J., Marques T., Leite R., Antunes F., Mansinho K., et al. Identification of relevant single-nucleotide polymorphisms in Pneumocystis jirovecii: relationship with clinical data. Clin Microbiol Infect 2010, 16:878-884.
15. Esteves F., Gaspar J., de Sousa B., Antunes F., Mansinho K., Matos O. Clinical relevance of multiple single-nucleotide polymorphisms in Pneumocystis jirovecii pneumonia: Development of a multiplex PCR-single-base-extension methodology. J Clin Microbiol 2011, 49:1810-1815.
16. Griffith D.E., Aksamit T., Brown-Elliott B.A., Catanzaro A., Daley C., Gordin F., et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 2007, 175:367-416. ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America.
17. Millar A.B., Patou G., Miller R.F., Grundy J.E., Katz D.R., Weller I.V., et al. Cytomegalovirus in the lungs of patients with AIDS: Respiratory pathogen or passenger?. Am J Respir Crit Care Med 1990, 141:1474-1477.
18. McKenzie R., Travis W.D., Dolan S.A., Pittaluga S., Feuerstein I.M., Selhamer J., et al. The causes of death in patients with human immunodeficiency virus infection: a clinical and pathologic study with emphasis on the role of pulmonary diseases. Medicine (Baltimore) 1991, 70:326-343.
19. Bozzette S.A., Arcia J., Bartok A.E., McGlynn L.M., McCutchan J.A., Richman D.D., et al. Impact of Pneumocystis carinii and cytomegalovirus on the course and outcome of atypical pneumonia in advanced human immunodeficiency virus disease. J Infect Dis 1992, 165:93-98.