The effects of Provent on moderate to severe obstructive sleep apnoea during continuous positive airway pressure therapy withdrawal: A randomised controlled trial

Thorax

Volumn 68, Issue 9, 2013, Pages 854-859

  Rossi, Valentina A ^a   Winter, Barbara ^b   Rahman, Najib M ^b   Yu, Ly Mee ^c   Fallon, Janet ^b   Clarenbach, Christian F ^a   Bloch, Konrad E ^a,d   Stradling, John R ^b   Kohler, Malcolm ^a,d  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b CHURCHILL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMBULATORY CARE; APNEA HYPOPNEA INDEX; ARTICLE; BLOOD PRESSURE MEASUREMENT; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DISEASE SEVERITY; EPWORTH SLEEPINESS SCALE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NASAL EXPIRATORY POSITIVE AIRWAY PRESSURE DEVICE; OUTPATIENT DEPARTMENT; OXYGEN DESATURATION; PATIENT ATTITUDE; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PULSE OXIMETER; PULSE OXIMETRY; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; SLEEP DISORDERED BREATHING; SWITZERLAND; TREATMENT OUTCOME; TREATMENT WITHDRAWAL; VENTILATOR;

SLEEP APNOEA;

AGED; BLOOD PRESSURE; CONTINUOUS POSITIVE AIRWAY PRESSURE; DISORDERS OF EXCESSIVE SOMNOLENCE; FEMALE; HUMANS; MALE; MIDDLE AGED; NOSE; OXIMETRY; OXYGEN; POLYSOMNOGRAPHY; PROSTHESES AND IMPLANTS; QUESTIONNAIRES; RECURRENCE; SEVERITY OF ILLNESS INDEX; SLEEP APNEA, OBSTRUCTIVE; WITHHOLDING TREATMENT;

EID: 84881556851     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2013-203508     Document Type: Article

References (15)

1. Young T, Palta M, Dempsey J, et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-5. (Pubitemid 23115702)
2. Jenkinson C, Davies RJ, Mullins R, et al. Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial. Lancet 1999;353:2100-5. (Pubitemid 29278478)
3. George CF. Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP. Thorax 2001;56:508-12. (Pubitemid 32588527)
4. Kohler M, Pepperell JCT, Casadei B, et al. CPAP and measures of cardiovascular risk in males with OSAS. Eur Respir J 2008;32:1488-96.
5. Kohler M, Smith D, Tippett V, et al. Predictors of long-term compliance with continuous positive airway pressure. Thorax 2010;65:829-32.
6. Braga CW, Chen Q, Burschtin OE, et al. Changes in lung volume and upper airway using MRI during application of nasal expiratory positive airway pressure in patients with sleep-disordered breathing. J Appl Physiol 2011;111:1400-9.
7. Colrain IM, Brooks S, Black J. A pilot evaluation of a nasal expiratory resistance device for the treatment of obstructive sleep apnea. J Clin Sleep Med 2008;4:426-33.
8. Rosenthal L, Massie CA, Dolan DC, et al. A multicenter, prospective study of a novel nasal EPAP device in the treatment of obstructive sleep apnea: efficacy and 30-day adherence. J Clin Sleep Med 2009;5:532-7.
9. Berry RB, Massie C, Kryger MH. A randomized controlled trial of nasal expiratory resistance as a treatment for obstructive sleep apnea. Sleep 2010;34:479-85.
10. Kohler M, Stoewhas AC, Ayers L, et al. The effects of CPAP therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial. Am J Respir Crit Care Med 2011;184:1192-9.
11. Johns MW. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep 1991;14:540-5.
12. Bloch KE, Schoch OD, Zhang JN, et al. German version of the Epworth Sleepiness Scale. Respiration 1999;66:440-7. (Pubitemid 29431578)
13. Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy. Proc Am Thorac Soc 2008;5:173-8.
14. Weaver TE, Kribbs NB, Pack AI, et al. Night-to-night variability in CPAP use over the first three months of treatment. Sleep 1997;20:278-83. (Pubitemid 27276642)
15. Phillips CL, Yee B, Yang Q, et al. Effect of continuous positive airway pressure treatment and withdrawal in patients with obstructive sleep apnea on arterial stiffness and central blood pressure. Chest 2008;134:94-100. (Pubitemid 352008769)