Down-regulation of microRNA-181b is a potential prognostic marker of non-small cell lung cancer

Pathology Research and Practice

Volumn 209, Issue 8, 2013, Pages 490-494

  Yang, Junquan ^a   Liu, Hongxia ^b   Wang, Hongbin ^a   Sun, Yuman ^b  

^a People's Hospital of Tangshan City   (China)

^b Department of Pathology   (China)

Author keywords

MicroRNA 181b; Non small cell lung cancer; Prognosis; Real time quantitative RT PCR assay

Indexed keywords

MICRORNA; MICRORNA 181B; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR VOLUME;

MICRORNA-181B; NON-SMALL CELL LUNG CANCER; PROGNOSIS; REAL-TIME QUANTITATIVE RT-PCR ASSAY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; DISEASE-FREE SURVIVAL; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MICRORNAS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROPORTIONAL HAZARDS MODELS; REAL-TIME POLYMERASE CHAIN REACTION; RISK FACTORS; TIME FACTORS; TUMOR BURDEN; TUMOR MARKERS, BIOLOGICAL;

EID: 84881554234     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2013.04.018     Document Type: Article

References (32)

1. Jemal A., Siegel R., Xu J., Ward E. Cancer statistics, 2010. CA Cancer J. Clin. 2010, 60:277-300.
2. Parkin D.M., Bray F., Ferlay J., Pisani P. Global cancer statistics, 2002. CA Cancer J. Clin. 2005, 55:74-108.
3. Spiro S.G., Silvestri G.A. One hundred years of lung cancer. Am. J. Respir. Crit. Care Med. 2005, 172:523-529.
4. Yoshizaki T., Motomura W., Tanno S., Kumei S., Yoshizaki Y., Tanno S., Okumura T. Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells. J Exp Clin. Cancer Res. 2010, 29:22.
5. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
6. Calin G.A., Croce C.M. MicroRNA signatures in human cancers. Nat. Rev. Cancer 2006, 6:857-866.
7. Johnson C.D., Esquela-Kerscher A., Stefani G., Byrom M., Kelnar K., Ovcharenko D., Wilson M., Wang X., Shelton J., Shingara J., Chin L., Brown D., Slack F.J. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 2007, 67:7713-7722.
8. Volinia S., Calin G.A., Liu C.G., Ambs S., Cimmino A., Petrocca F., Visone R., Iorio M., Roldo C., Ferracin M., Prueitt R.L., Yanaihara N., Lanza G., Scarpa A., Vecchione A., Negrini M., Harris C.C., Croce C.M. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:2257-2261.
9. Moussay E., Wang K., Cho J.H., van Moer K., Pierson S., Paggetti J., Nazarov P.V., Palissot V., Hood L.E., Berchem G., Galas D.J. MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:6573-6578.
10. Liu J., Lu K.H., Liu Z.L., Sun M., De W., Wang Z.X. MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1. BMC Cancer 2012, 12:519.
11. Saito M., Schetter A.J., Mollerup S., Kohno T., Skaug V., Bowman E.D., Mathé E.A., Takenoshita S., Yokota J., Haugen A., Harris C.C. The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts. Clin Cancer Res. 2011, 17:1875-1882.
12. Chen L.T., Xu S.D., Xu H., Zhang J.F., Ning J.F., Wang S.F. MicroRNA-378 is associated with non-small cell lung cancer brain metastasis by promoting cell migration, invasion and tumor angiogenesis. Med Oncol. 2012, 29:1673-1680.
13. Chen C.Z., Li L., Lodish H.F., Bartel D.P. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004, 303:83-86.
14. Li Q.J., Chau J., Ebert P.J., Sylvester G., Min H., Liu G., Braich R., Manoharan M., Soutschek J., Skare P., Klein L.O., Davis M.M., Chen C.Z. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 2007, 129:147-161.
15. Kazenwadel J., Michael M.Z., Harvey N.L. Prox1 expression is negatively regulated by miR-181 in endothelial cells. Blood 2010, 116:2395-2401.
16. de Yébenes V.G., Belver L., Pisano D.G., González S., Villasante A., Croce C., He L., Ramiro A.R. miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J. Exp. Med. 2008, 205:2106-2199.
17. Visone R., Veronese A., Balatti V., Croce C.M. MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia. Oncotarget 2012, 3:195-202.
18. Shi Z.M., Wang X.F., Qian X., Tao T., Wang L., Chen Q.D., Wang X.R., Cao L., Wang Y.Y., Zhang J.X., Jiang T., Kang C.S., Jiang B.H., Liu N., You Y.P. MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas. RNA 2013, 19:552-560.
19. Ciafrè S.A., Galardi S., Mangiola A., Ferracin M., Liu C.G., Sabatino G., Negrini M., Maira G., Croce C.M., Farace M.G. Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem. Biophys. Res. Commun. 2005, 334:1351-1358.
20. Jiang J., Zheng X., Xu X., Zhou Q., Yan H., Zhang X., Lu B., Wu C., Ju J. Prognostic significance of miR-181b and miR-21 in gastric cancer patients treated with S-1/oxaliplatin or doxifluridine/oxaliplatin. PLoS ONE 2011, 6:e23271.
21. Zhu W., Shan X., Wang T., Shu Y., Liu P. miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int. J. Cancer 2010, 127:2520-2529.
22. Zhi F., Chen X., Wang S., Xia X., Shi Y., Guan W., Shao N., Qu H., Yang C., Zhang Y., Wang Q., Wang R., Zen K., Zhang C.Y., Zhang J., Yang Y. The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma. Eur. J. Cancer 2010, 46:1640-1649.
23. Havelange V., Stauffer N., Heaphy C.C., Volinia S., Andreeff M., Marcucci G., Croce C.M., Garzon R. Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profiling. Cancer 2011, 117:4696-4706.
24. Xu X., Jia R., Zhou Y., Song X., Wang J., Qian G., Ge S., Fan X. Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells. Int. J. Oncol. 2011, 38:1385-1393.
25. Cai B., An Y., Lv N., Chen J., Tu M., Sun J., Wu P., Wei J., Jiang K., Miao Y. miRNA-181b increases the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine in vitro and in nude mice by targeting BCL-2. Oncol. Rep. 2013, 29:1769-1776.
26. Jones K.B., Salah Z., Del Mare S., Galasso M., Gaudio E., Nuovo G.J., Lovat F., LeBlanc K., Palatini J., Randall R.L., Volinia S., Stein G.S., Croce C.M., Lian J.B., Aqeilan R.I. miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res. 2012, 72:1865-1877.
27. Nurul-Syakima A.M., Yoke-Kqueen C., Sabariah A.R., Shiran M.S., Singh A., Learn-Han L. Differential microRNA expression and identification of putative miRNA targets and pathways in head and neck cancers. Int. J. Mol. Med. 2011, 28:327-336.
28. Guo J.X., Tao Q.S., Lou P.R., Chen X.C., Chen J., Yuan G.B. miR-181b as a potential molecular target for anticancer therapy of gastric neoplasms. Asian Pac. J. Cancer Prev. 2012, 13:2263-2267.
29. Chen L., Yang Q., Kong W.Q., Liu T., Liu M., Li X., Tang H. MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. IUBMB Life 2012, 64:628-635.
30. Hong T.M., Chen Y.L., Wu Y.Y., Yuan A., Chao Y.C., Chung Y.C., Wu M.H., Yang S.C., Pan S.H., Shih J.Y., Chan W.K., Yang P.C. Targeting neuropilin 1 as an antitumor strategy in lung cancer. Clin. Cancer Res. 2007, 13:4759-4768.
31. Hongxia L.I.U. Expression of nueropilin-1 in non-small cell lung cancer and its clinical significance. Prac. Prevent. Med. 2011, 18:1941-1944. (in Chinese).
32. Cui Y., Han Z., Hu Y., Song G., Hao C., Xia H., Ma X. MicroRNA-181b and microRNA-9 mediate arsenic-induced angiogenesis via NRP1. J. Cell Physiol. 2012, 227:772-783.