메뉴 건너뛰기




Volumn 39, Issue 7, 2013, Pages 753-758

Fulvestrant for advanced breast cancer: A meta-analysis

Author keywords

Aromatase inhibitors; Breast cancer; Fulvestrant; Tamoxifen

Indexed keywords

ANASTROZOLE; AROMATASE INHIBITOR; FULVESTRANT; TAMOXIFEN;

EID: 84881551484     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2013.03.004     Document Type: Review
Times cited : (30)

References (30)
  • 1
    • 0034023827 scopus 로고    scopus 로고
    • Similarities and distinctions in the mode of action of different classes of antioestrogens
    • Wakeling A.E. Similarities and distinctions in the mode of action of different classes of antioestrogens. Endocr Relat Cancer 2000, 7(1):17-28.
    • (2000) Endocr Relat Cancer , vol.7 , Issue.1 , pp. 17-28
    • Wakeling, A.E.1
  • 2
    • 0029075872 scopus 로고
    • Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer
    • Osborne C.K., et al. Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer. J Natl Cancer Inst 1995, 87(10):746-750.
    • (1995) J Natl Cancer Inst , vol.87 , Issue.10 , pp. 746-750
    • Osborne, C.K.1
  • 3
    • 0028861402 scopus 로고
    • Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer
    • Howell A., et al. Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer. Lancet 1995, 345(8941):29-30.
    • (1995) Lancet , vol.345 , Issue.8941 , pp. 29-30
    • Howell, A.1
  • 4
    • 0037102121 scopus 로고    scopus 로고
    • Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment
    • Howell A., et al. Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. J Clin Oncol 2002, 20(16):3396-3403.
    • (2002) J Clin Oncol , vol.20 , Issue.16 , pp. 3396-3403
    • Howell, A.1
  • 5
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial
    • Osborne C.K., et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial. J Clin Oncol 2002, 20(16):3386-3395.
    • (2002) J Clin Oncol , vol.20 , Issue.16 , pp. 3386-3395
    • Osborne, C.K.1
  • 6
    • 2442648038 scopus 로고    scopus 로고
    • Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial
    • Howell A., et al. Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial. J Clin Oncol 2004, 22(9):1605-1613.
    • (2004) J Clin Oncol , vol.22 , Issue.9 , pp. 1605-1613
    • Howell, A.1
  • 7
    • 34548241775 scopus 로고    scopus 로고
    • Fulvestrant (Faslodex) - how to make a good drug better
    • Robertson J.F. Fulvestrant (Faslodex) - how to make a good drug better. Oncologist 2007, 12(7):774-784.
    • (2007) Oncologist , vol.12 , Issue.7 , pp. 774-784
    • Robertson, J.F.1
  • 8
    • 43249130208 scopus 로고    scopus 로고
    • Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT
    • Chia S., et al. Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT. J Clin Oncol 2008, 26(10):1664-1670.
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1664-1670
    • Chia, S.1
  • 9
    • 84881554211 scopus 로고    scopus 로고
    • Fulvestrant alone or with concomitant anastrozole vs exemestane following progression on non-steroidal aromatase inhibitor - first results of the SoFEa trial (CRUKE/03/021 & CRUK/09/007) (ISRCTN44195747). Abstract LBA2, presented at EBCC-8, 2012.
    • Johnston S et al. Fulvestrant alone or with concomitant anastrozole vs exemestane following progression on non-steroidal aromatase inhibitor - first results of the SoFEa trial (CRUKE/03/021 & CRUK/09/007) (ISRCTN44195747). Abstract LBA2, presented at EBCC-8, 2012.
    • Johnston, S.1
  • 10
    • 84863892191 scopus 로고    scopus 로고
    • FACT: an open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer
    • Bergh J., et al. FACT: an open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer. J Clin Oncol 2012, 30(16):1919-1925.
    • (2012) J Clin Oncol , vol.30 , Issue.16 , pp. 1919-1925
    • Bergh, J.1
  • 11
    • 84864512253 scopus 로고    scopus 로고
    • Combination anastrozole and fulvestrant in metastatic breast cancer
    • Mehta R.S., et al. Combination anastrozole and fulvestrant in metastatic breast cancer. N Engl J Med 2012, 367(5):435-444.
    • (2012) N Engl J Med , vol.367 , Issue.5 , pp. 435-444
    • Mehta, R.S.1
  • 12
    • 78049523306 scopus 로고    scopus 로고
    • Results of the CONFIRM phase III trial comparing fulvestrant 250mg with fulvestrant 500mg in postmenopausal women with estrogen receptor-positive advanced breast cancer
    • Di Leo A., et al. Results of the CONFIRM phase III trial comparing fulvestrant 250mg with fulvestrant 500mg in postmenopausal women with estrogen receptor-positive advanced breast cancer. J Clin Oncol 2010, 28(30):4594-4600.
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. 4594-4600
    • Di Leo, A.1
  • 13
    • 84881547117 scopus 로고    scopus 로고
    • Final analysis of overall survival for the Phase III CONFIRM trial: fulvestrant 500mg versus 250mg. San Antonio Breast Cancer Symposium, San Antonio (TX), December 4-8; 2012 (Abstract S1-4).
    • Di Leo A, Jerusalem G, Petruzelka L, et al. Final analysis of overall survival for the Phase III CONFIRM trial: fulvestrant 500mg versus 250mg. San Antonio Breast Cancer Symposium, San Antonio (TX), December 4-8; 2012 (Abstract S1-4).
    • Di Leo, A.1    Jerusalem, G.2    Petruzelka, L.3
  • 14
    • 84881550897 scopus 로고    scopus 로고
    • FASLODEX® (fulvestrant) injection. US FDA-approved manufacturer's package insert. Available from: [accessed on October 12 2012].
    • FASLODEX® (fulvestrant) injection. US FDA-approved manufacturer's package insert. Available from: [accessed on October 12 2012]. http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021344s007s012lbl.pdf.
  • 15
    • 70350221678 scopus 로고    scopus 로고
    • Predicting benefit from fulvestrant in pretreated metastatic breast cancer patients
    • Freedman O., et al. Predicting benefit from fulvestrant in pretreated metastatic breast cancer patients. Breast Cancer Res Treat 2009, 118(2):377-383.
    • (2009) Breast Cancer Res Treat , vol.118 , Issue.2 , pp. 377-383
    • Freedman, O.1
  • 16
    • 76749091057 scopus 로고    scopus 로고
    • Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: results from the FIRST study
    • Robertson J.F., et al. Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: results from the FIRST study. J Clin Oncol 2009, 27(27):4530-4535.
    • (2009) J Clin Oncol , vol.27 , Issue.27 , pp. 4530-4535
    • Robertson, J.F.1
  • 17
    • 84887023435 scopus 로고    scopus 로고
    • http://www.clinicaltrials.gov/ct2/show/NCT01602380.
  • 18
    • 84881545901 scopus 로고    scopus 로고
    • Analysing and presenting results. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions (version 5.1.0). The Cochrane Collaboration; 2011.
    • Shemilt I, Mugford M, Byford S, et al. Analysing and presenting results. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions (version 5.1.0). The Cochrane Collaboration; 2011. http://www.cochrane-handbook.org.
    • Shemilt, I.1    Mugford, M.2    Byford, S.3
  • 19
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DerSimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7(3):177-188.
    • (1986) Control Clin Trials , vol.7 , Issue.3 , pp. 177-188
    • DerSimonian, R.1    Laird, N.2
  • 20
    • 2342661718 scopus 로고    scopus 로고
    • What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data
    • Sweeting M.J., Sutton A.J., Lambert P.C. What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data. Stat Med 2004, 23(9):1351-1375.
    • (2004) Stat Med , vol.23 , Issue.9 , pp. 1351-1375
    • Sweeting, M.J.1    Sutton, A.J.2    Lambert, P.C.3
  • 21
    • 84881552925 scopus 로고    scopus 로고
    • Metaanalysis of rare events. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions (version 5.1.0). The Cochrane Collaboration; 2011.
    • Higgins JPT, Deeks JJ, Altman DG. Metaanalysis of rare events. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions (version 5.1.0). The Cochrane Collaboration; 2011. http://www.cochrane-handbook.org.
    • Higgins, J.P.T.1    Deeks, J.J.2    Altman, D.G.3
  • 22
    • 0035928514 scopus 로고    scopus 로고
    • Systematic reviews in health care: systematic reviews of evaluations of diagnostic and screening tests
    • Deeks J.J. Systematic reviews in health care: systematic reviews of evaluations of diagnostic and screening tests. BMJ 2001, 323(7305):157-162.
    • (2001) BMJ , vol.323 , Issue.7305 , pp. 157-162
    • Deeks, J.J.1
  • 23
    • 84881555420 scopus 로고    scopus 로고
    • A comparison of fulvestrant 500mg with anastrozole as first-line treatment for advanced breast cancer: follow-up analysis from the 'FIRST' study. San Antonio Breast Cancer Symposium, San Antonio (TX), December 8-12; 2010 (abstr. S1-3).
    • Robertson JFR, Lindemann JPO, Llombart-Cussac A, et al. A comparison of fulvestrant 500mg with anastrozole as first-line treatment for advanced breast cancer: follow-up analysis from the 'FIRST' study. San Antonio Breast Cancer Symposium, San Antonio (TX), December 8-12; 2010 (abstr. S1-3).
    • Robertson, J.F.R.1    Lindemann, J.P.O.2    Llombart-Cussac, A.3
  • 24
    • 77951033352 scopus 로고    scopus 로고
    • Thiochroman derivative CH4986399, a new nonsteroidal estrogen receptor down-regulator, is effective in breast cancer models
    • Yoneya T., et al. Thiochroman derivative CH4986399, a new nonsteroidal estrogen receptor down-regulator, is effective in breast cancer models. Anticancer Res 2010, 30(3):873-878.
    • (2010) Anticancer Res , vol.30 , Issue.3 , pp. 873-878
    • Yoneya, T.1
  • 25
    • 34247536303 scopus 로고    scopus 로고
    • Characterization of molecular and structural determinants of selective estrogen receptor downregulators
    • Fan M., et al. Characterization of molecular and structural determinants of selective estrogen receptor downregulators. Breast Cancer Res Treat 2007, 103(1):37-44.
    • (2007) Breast Cancer Res Treat , vol.103 , Issue.1 , pp. 37-44
    • Fan, M.1
  • 26
    • 77957936884 scopus 로고    scopus 로고
    • Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8769 early-stage breast cancer patients
    • Hershman D.L., et al. Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8769 early-stage breast cancer patients. J Clin Oncol 2010, 28(27):4120-4128.
    • (2010) J Clin Oncol , vol.28 , Issue.27 , pp. 4120-4128
    • Hershman, D.L.1
  • 27
    • 78349308644 scopus 로고    scopus 로고
    • Defining ovarian failure in amenorrheic young breast cancer patients
    • Amir E., et al. Defining ovarian failure in amenorrheic young breast cancer patients. Breast 2010, 19(6):545-548.
    • (2010) Breast , vol.19 , Issue.6 , pp. 545-548
    • Amir, E.1
  • 28
    • 84879271633 scopus 로고    scopus 로고
    • Amenorrhoea, menopause, and endocrine therapy for breast cancer
    • Amir E., et al. Amenorrhoea, menopause, and endocrine therapy for breast cancer. BMJ 2009, 3(339).
    • (2009) BMJ , vol.3 , Issue.339
    • Amir, E.1
  • 29
    • 84881554964 scopus 로고    scopus 로고
    • European Medicines Agency. Faslodex: summary of product characteristics. Available from: [accessed October 20 2012].
    • European Medicines Agency. Faslodex: summary of product characteristics. Available from: [accessed October 20 2012]. http://www.emea.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000540/WC500021174.pdf.
  • 30
    • 84881551325 scopus 로고    scopus 로고
    • [last accessed on October 29 2012].
    • [last accessed on October 29 2012]. http://clinicaltrials.gov/show/NCT00075764.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.