An unmatched case controlled study of clinicopathologic abnormalities in dogs with Bartonella infection

Comparative Immunology, Microbiology and Infectious Diseases

Volumn 36, Issue 5, 2013, Pages 481-487

  Pérez Vera, Cristina ^a   Diniz, Pedro Paulo V P ^b   Pultorak, Elizabeth L ^a   Maggi, Ricardo G ^a   Breitschwerdt, Edward B ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

BAPGM; Bartonella; Dogs; Enrichment PCR; Hypoglobulinemia

Indexed keywords

BACTERIAL DNA; CREATININE;

ANAMNESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHROCENTESIS; ARTICLE; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BARTONELLA; BARTONELLA BOVIS; BARTONELLA HENSELAE; BARTONELLA KOEHLERAE; BARTONELLA VINSONII; BARTONELLA VINSONII BERKHOFFII; BARTONELLA VOLANS; BARTONELLOSIS; BLOOD PROTEIN DISORDER; CLINICAL FEATURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DATA ANALYSIS; DNA SEQUENCE; DOG DISEASE; ENRICHMENT CULTURE; FEMALE; HYPOGLOBULINEMIA; INFLAMMATION; JOINT EFFUSION; MALE; MEDICAL RECORD REVIEW; NEUTROPENIA; NEUTROPHILIA; NEUTROPHILIC INFLAMMATION; NONHUMAN; POLYARTHRITIS; POLYMERASE CHAIN REACTION; SERODIAGNOSIS; SKIN DEFECT; SYMPTOMATOLOGY; WEIGHT REDUCTION;

BARTONELLA; BARTONELLA BOVIS; BARTONELLA HENSELAE; BARTONELLA KOEHLERAE; BARTONELLA SP.; BARTONELLA VINSONII SUBSP. BERKHOFFII; CANIS FAMILIARIS;

BAPGM; BARTONELLA; DOGS; ENRICHMENT PCR; HYPOGLOBULINEMIA;

ANIMALS; BARTONELLA; BARTONELLA INFECTIONS; BASE SEQUENCE; BLOOD PROTEIN DISORDERS; CASE-CONTROL STUDIES; DNA, BACTERIAL; DOG DISEASES; DOGS; FEMALE; IMMUNOLOGIC DEFICIENCY SYNDROMES; MALE; SEQUENCE ANALYSIS, DNA; WEIGHT LOSS;

EID: 84881543970     PISSN: 01479571     EISSN: 18781667     Source Type: Journal    
DOI: 10.1016/j.cimid.2013.04.001     Document Type: Article

References (24)

1. Breitschwerdt E.B., Maggi R.G., Chomel B.B., Lappin M.R. Bartonellosis: an emerging infectious disease of zoonotic importance to animals and human beings. Journal of Veterinary Emergency and Critical Care (San Antonio) 2010, 20:8-30.
2. Pérez C., Maggi R.G., Diniz P.P., Breitschwerdt E.B. Molecular and serological diagnosis of Bartonella infection in 61 dogs from the United States. Journal of Veterinary Internal Medicine 2011, 25:805-810.
3. Pappalardo B.L., Brown T., Gebhardt D., Sontakke S., Breitschwerdt E.B. Cyclic CD8+ lymphopenia in dogs experimentally infected with Bartonella vinsonii subsp. berkhoffii. Veterinary Immunology and Immunopathology 2000, 75:43-57.
4. Pappalardo B.L., Brown T.T., Tompkins M., Breitschwerdt E.B. Immunopathology of Bartonella vinsonii (berkhoffii) in experimentally infected dogs. Veterinary Immunology and Immunopathology 2001, 83:125-147.
5. Pulliainen A.T., Dehio C. Persistence of Bartonella spp. stealth pathogens: from sub-clinical infections to vasoproliferative tumour formation. FEMS Microbiology Review 2012, 36:563-599.
6. Tsai Y.L., Chang C.C., Chuang S.T., Chomel B.B. Bartonella species and their ectoparasites: selective host adaptation or strain selection between the vector and the mammalian host?. Comparative Immunology, Microbiology and Infectious Diseases 2011, 34:299-314.
7. Breitschwerdt E.B., Kordick D.L., Malarkey D.E., Keene B., Hadfield T.L., Wilson K. Endocarditis in a dog due to infection with a novel Bartonella subspecies. Journal of Clinical Microbiology 1995, 33:154-160.
8. Saunders G.K., Monroe W.E. Systemic granulomatous disease and sialometaplasia in a dog with Bartonella infection. Veterinary Pathology 2006, 43:391-392.
9. Yager J.A., Best S.J., Maggi R.G., Varanat M., Znajda N., Breitschwerdt E.B. Bacillary angiomatosis in an immunosuppressed dog. Veterinary Dermatology 2010, 21:420-428.
10. Breitschwerdt E.B., Blann K.R., Stebbins M.E., Muñana K.R., Davidson M.G., Jackson H.A., et al. Clinicopathological abnormalities and treatment response in 24 dogs seroreactive to Bartonella vinsonii (berkhoffii) antigens. Journal of the American Animal Hospital Association 2004, 40:92-101.
11. Goodman R.A., Breitschwerdt E.B. Clinicopathologic findings in dogs seroreactive to Bartonella henselae antigens. American Journal of Veterinary Research 2005, 66:2060-2064.
12. Henn J.B., Liu C.H., Kasten R.W., VanHorn B.A., Beckett L.A., Kass P.H., et al. Seroprevalence of antibodies against Bartonella species and evaluation of risk factors and clinical signs associated with seropositivity in dogs. American Journal of Veterinary Research 2005, 66:688-694.
13. de Caprariis D., Dantas-Torres F., Capelli G., Mencke N., Stanneck D., Breitschwerdt E.B., et al. Evolution of clinical, haematological and biochemical findings in young dogs naturally infected by vector-borne pathogens. Veterinary Microbiology 2011, 149:206-212.
14. Kordick S.K., Breitschwerdt E.B., Hegarty B.C., Southwick K.L., Colitz C.M., Hancock S.I., et al. Coinfection with multiple tick-borne pathogens in a Walker Hound kennel in North Carolina. Journal of Clinical Microbiology 1999, 37:2631-2638.
15. Diniz P.P., Maggi R.G., Schwartz D.S., Cadenas M.B., Bradley J.M., Hegarty B., et al. Canine bartonellosis: serological and molecular prevalence in Brazil and evidence of co-infection with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii. Veterinary Research 2007, 38:697-710.
16. Duncan A.W., Maggi R.G., Breitschwerdt E.B. A combined approach for the enhanced detection and isolation of Bartonella species in dog blood samples: pre-enrichment liquid culture followed by PCR and subculture onto agar plates. Journal of Microbiological Methods 2007, 69:273-281.
17. Maggi R.G., Duncan A.W., Breitschwerdt E.B. Novel chemically modified liquid medium that will support the growth of seven Bartonella species. Journal of Clinical Microbiology 2005, 43:2651-2655.
18. Cherry N.A., Diniz P.P., Maggi R.G., Hummel J.B., Hardie E.M., Behrend E.N., et al. Isolation or molecular detection of Bartonella henselae and Bartonella vinsonii subsp. berkhoffii from dogs with idiopathic cavitary effusions. Journal of Veterinary Internal Medicine 2009, 23:186-189.
19. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. Journal of Molecular Biology 1990, 215:403-410.
20. ® System 2000, SAS Publishing, Cary, North Carolina. 2nd edition.
21. Hosmer D.W., Lemeshow S. Applied Logistic Regression 2001, Wiley Publishing, New Jersey. 2nd edition.
22. Hirji K.F., Mehta C.R., Patel N.R. Computing distributions for exact logistic regression. JASA 1987, 82:1110-1117.
23. Liu Q.J., Zeng Q., Zhou Y.R. Exact logistic regression and its performance to SAS system. Zhonghua Liu Xing Bing Xue Za Zhi 2003, 24:725-728.
24. Greenland S., Schwartzbaum J.A., Finkle W.D. Problems due to small samples and sparse data in conditional logistic regression analysis. American Journal of Epidemiology 2000, 151:531-539.