메뉴 건너뛰기




Volumn 2013, Issue , 2013, Pages

Tuning aerosol particle size distribution of metered dose inhalers using cosolvents and surfactants

Author keywords

[No Author keywords available]

Indexed keywords

APAFLURANE; EXCIPIENT; SOLVENT; SURFACTANT; AEROSOL; ALCOHOL; FLUORESCEIN; FLUORINATED HYDROCARBON; NORFLURANE; POLOXAMER;

EID: 84881537639     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/574310     Document Type: Article
Times cited : (22)

References (31)
  • 1
    • 0036940766 scopus 로고    scopus 로고
    • Pulmonary drug delivery systems: Recent developments and prospects
    • DOI 10.1615/CritRevTherDrugCarrierSyst.v19.i45.40
    • Courrier H. M., Butz N., Vandamme T. F., Pulmonary drug delivery systems: recent developments and prospects. Critical Reviews in Therapeutic Drug Carrier Systems 2002 19 4-5 425 498 2-s2.0-0036940766 10.1615/ CritRevTherDrugCarrierSyst.v19.i45.40 (Pubitemid 36314479)
    • (2002) Critical Reviews in Therapeutic Drug Carrier Systems , vol.19 , Issue.4-5 , pp. 425-498
    • Courrier, H.M.1    Butz, N.2    Vandamme, Th.F.3
  • 2
    • 0031389982 scopus 로고    scopus 로고
    • Atomization mechanisms of the pressurized metered dose inhaler
    • Dunbar C. A., Atomization mechanisms of the pressurized metered dose inhaler. Particulate Science and Technology 1997 15 3-4 253 271 2-s2.0-0031389982 (Pubitemid 28449122)
    • (1997) Particulate Science and Technology , vol.15 , Issue.3-4 , pp. 253-271
    • Dunbar, C.A.1
  • 3
    • 0034658554 scopus 로고    scopus 로고
    • Transition to CFC-free metered dose inhalers - Into the new millennium
    • DOI 10.1016/S0378-5173(00)00401-4, PII S0378517300004014
    • McDonald K. J., Martin G. P., Transition to CFC-free metered dose inhalers-into the new millennium. International Journal of Pharmaceutics 2000 201 1 89 107 2-s2.0-0034658554 10.1016/S0378-5173(00)00401-4 (Pubitemid 30364973)
    • (2000) International Journal of Pharmaceutics , vol.201 , Issue.1 , pp. 89-107
    • McDonald, K.J.1    Martin, G.P.2
  • 4
    • 0029165058 scopus 로고
    • CFC's their replacement and the ozone layer
    • supplement 1
    • Noakes T. J., CFC's their replacement and the ozone layer. Journal of Aerosol Medicine 1995 8 supplement 1 S3 S7
    • (1995) Journal of Aerosol Medicine , vol.8
    • Noakes, T.J.1
  • 5
    • 0032790248 scopus 로고    scopus 로고
    • Drug-surfactant-propellant interactions in HFA-formulations
    • DOI 10.1016/S0378-5173(99)00134-9, PII S0378517399001349
    • Vervaet C., Byron P. R., Drug-surfactant-propellant interactions in HFA-formulations. International Journal of Pharmaceutics 1999 186 1 13 30 2-s2.0-0032790248 10.1016/S0378-5173(99)00134-9 (Pubitemid 29397519)
    • (1999) International Journal of Pharmaceutics , vol.186 , Issue.1 , pp. 13-30
    • Vervaet, C.1    Byron, P.R.2
  • 6
    • 0029162644 scopus 로고
    • Safety of propellants
    • 2-s2.0-0029162644
    • Alexander D. J., Safety of propellants. Journal of Aerosol Medicine 1995 8 1 S29 S34 2-s2.0-0029162644
    • (1995) Journal of Aerosol Medicine , vol.8 , Issue.1
    • Alexander, D.J.1
  • 7
    • 0031679782 scopus 로고    scopus 로고
    • Surfactant dissolution and water solubilization in chlorine-free liquified gas propellants
    • Blondino F. E., Byron P. R., Surfactant dissolution and water solubilization in chlorine-free liquified gas propellants. Drug Development and Industrial Pharmacy 1998 24 10 935 945 2-s2.0-0031679782 (Pubitemid 28470970)
    • (1998) Drug Development and Industrial Pharmacy , vol.24 , Issue.10 , pp. 935-945
    • Blondino, F.E.1    Byron, P.R.2
  • 8
    • 0038433196 scopus 로고    scopus 로고
    • The influence of formulation variables on the performance of alternative propellant-driven metered dose inhalers
    • DOI 10.1016/S0169-409X(03)00079-6
    • Smyth H. D. C., The influence of formulation variables on the performance of alternative propellant-driven metered dose inhalers. Advanced Drug Delivery Reviews 2003 55 7 807 828 2-s2.0-0038433196 10.1016/S0169-409X(03)00079-6 (Pubitemid 36776795)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.7 , pp. 807-828
    • Smyth, H.D.C.1
  • 9
    • 0032438394 scopus 로고    scopus 로고
    • Improved airway targeting with the CFC-free HFA-beclomethasone metered- dose inhaler compared with CFC-beclomethasone
    • DOI 10.1183/09031936.98.12061346
    • Leach C. L., Davidson P. J., Boudreau R. J., Improved airway targeting with the CFC-free HFA-beclomethasone metered- dose inhaler compared with CFC-beclomethasone. European Respiratory Journal 1998 12 6 1346 1353 2-s2.0-0032438394 10.1183/09031936.98.12061346 (Pubitemid 29011427)
    • (1998) European Respiratory Journal , vol.12 , Issue.6 , pp. 1346-1353
    • Leach, C.L.1    Davidson, P.J.2    Boudreau, R.J.3
  • 11
    • 23144453911 scopus 로고    scopus 로고
    • Multimodal particle size distributions emitted from HFA-134a solution pressurized metered-dose inhalers
    • 2-s2.0-17944395204
    • Smyth H. D. C., Hickey A. J., Multimodal particle size distributions emitted from HFA-134a solution pressurized metered-dose inhalers. AAPS PharmSciTech 2003 4 3 E38 2-s2.0-17944395204
    • (2003) AAPS PharmSciTech , vol.4 , Issue.3
    • Smyth, H.D.C.1    Hickey, A.J.2
  • 12
    • 33745620446 scopus 로고    scopus 로고
    • Spray pattern analysis for metered dose inhalers: Effect of actuator design
    • DOI 10.1007/s11095-006-0280-z
    • Smyth H., Brace G., Barbour T., Gallion J., Grove J., Hickey A. J., Spray pattern analysis for metered dose inhalers: effect of actuator design. Pharmaceutical Research 2006 23 7 1591 1596 2-s2.0-33745620446 10.1007/s11095-006-0280-z (Pubitemid 43993822)
    • (2006) Pharmaceutical Research , vol.23 , Issue.7 , pp. 1591-1596
    • Smyth, H.1    Brace, G.2    Barbour, T.3    Gallion, J.4    Grove, J.5    Hickey, A.J.6
  • 13
    • 33749460787 scopus 로고    scopus 로고
    • Spray pattern analysis for metered dose inhalers I: Orifice size, particle size, and droplet motion correlations
    • DOI 10.1080/03639040600637598, PII Q16K667H46TU3G15
    • Smyth H., Hickey A. J., Brace G., Barbour T., Gallion J., Grove J., Spray pattern analysis for metered dose inhalers I: orifice size, particle size, and droplet motion correlations. Drug Development and Industrial Pharmacy 2006 32 9 1033 1041 2-s2.0-33749460787 10.1080/03639040600637598 (Pubitemid 44521821)
    • (2006) Drug Development and Industrial Pharmacy , vol.32 , Issue.9 , pp. 1033-1041
    • Smyth, H.1    Hickey, A.J.2    Brace, G.3    Barbour, T.4    Gallion, J.5    Grove, J.6
  • 14
    • 0034278559 scopus 로고    scopus 로고
    • In-vitro characterisation of metered dose inhaler versus dry powder inhaler glucocorticoid products: Influence of inspiratory flow rates
    • 2-s2.0-0034278559
    • Feddah M. R., Brown K. F., Gipps E. M., Davies N. M., In-vitro characterisation of metered dose inhaler versus dry powder inhaler glucocorticoid products: influence of inspiratory flow rates. Journal of Pharmacy & Pharmaceutical Sciences 2000 3 3 318 324 2-s2.0-0034278559
    • (2000) Journal of Pharmacy & Pharmaceutical Sciences , vol.3 , Issue.3 , pp. 318-324
    • Feddah, M.R.1    Brown, K.F.2    Gipps, E.M.3    Davies, N.M.4
  • 16
    • 43849099717 scopus 로고    scopus 로고
    • Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin
    • 2-s2.0-43849099717 10.1016/j.colsurfb.2008.01.021
    • Gao Y., Li L. B., Zhai G., Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin. Colloids and Surfaces B 2008 64 2 194 199 2-s2.0-43849099717 10.1016/j.colsurfb.2008.01.021
    • (2008) Colloids and Surfaces B , vol.64 , Issue.2 , pp. 194-199
    • Gao, Y.1    Li, L.B.2    Zhai, G.3
  • 17
    • 43449084030 scopus 로고    scopus 로고
    • Polymeric micelles in oral chemotherapy
    • 2-s2.0-43449084030 10.1016/j.jconrel.2008.01.018
    • Bromberg L., Polymeric micelles in oral chemotherapy. Journal of Controlled Release 2008 128 2 99 112 2-s2.0-43449084030 10.1016/j.jconrel.2008. 01.018
    • (2008) Journal of Controlled Release , vol.128 , Issue.2 , pp. 99-112
    • Bromberg, L.1
  • 18
    • 0037151313 scopus 로고    scopus 로고
    • Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery
    • DOI 10.1016/S0168-3659(02)00009-3, PII S0168365902000093
    • Kabanov A. V., Batrakova E. V., Alakhov V. Y., Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery. Journal of Controlled Release 2002 82 2-3 189 212 2-s2.0-0037151313 10.1016/S0168-3659(02)00009-3 (Pubitemid 34880178)
    • (2002) Journal of Controlled Release , vol.82 , Issue.2-3 , pp. 189-212
    • Kabanov, A.V.1    Batrakova, E.V.2    Alakhov, V.Y.3
  • 19
    • 60849136012 scopus 로고    scopus 로고
    • Reverse aqueous emulsions and microemulsions in HFA227 propellant stabilized by non-ionic ethoxylated amphiphiles
    • 2-s2.0-60849136012 10.1016/j.ijpharm.2008.10.025
    • Chokshi U., Selvam P., Porcar L., da Rocha S. R. P., Reverse aqueous emulsions and microemulsions in HFA227 propellant stabilized by non-ionic ethoxylated amphiphiles. International Journal of Pharmaceutics 2009 369 1-2 176 184 2-s2.0-60849136012 10.1016/j.ijpharm.2008.10.025
    • (2009) International Journal of Pharmaceutics , vol.369 , Issue.1-2 , pp. 176-184
    • Chokshi, U.1    Selvam, P.2    Porcar, L.3    Da Rocha, S.R.P.4
  • 20
    • 0033744239 scopus 로고    scopus 로고
    • An investigation of the solubility of various compounds in the hydrofluoroalkane propellants and possible model liquid propellants
    • 2-s2.0-0033744239
    • Dickinson P. A., Seville P. C., McHale H., Perkins N. C., Taylor G., An investigation of the solubility of various compounds in the hydrofluoroalkane propellants and possible model liquid propellants. Journal of Aerosol Medicine 2000 13 3 179 186 2-s2.0-0033744239
    • (2000) Journal of Aerosol Medicine , vol.13 , Issue.3 , pp. 179-186
    • Dickinson, P.A.1    Seville, P.C.2    McHale, H.3    Perkins, N.C.4    Taylor, G.5
  • 21
    • 33746457772 scopus 로고    scopus 로고
    • Investigation into the influence of polymeric stabilizing excipients on inter-particulate forces in pressurised metered dose inhalers
    • DOI 10.1016/j.ijpharm.2006.04.016, PII S0378517306003425
    • Traini D., Young P. M., Rogueda P., Price R., Investigation into the influence of polymeric stabilizing excipients on inter-particulate forces in pressurised metered dose inhalers. International Journal of Pharmaceutics 2006 320 1-2 58 63 2-s2.0-33746457772 10.1016/j.ijpharm.2006.04.016 (Pubitemid 44128717)
    • (2006) International Journal of Pharmaceutics , vol.320 , Issue.1-2 , pp. 58-63
    • Traini, D.1    Young, P.M.2    Rogueda, P.3    Price, R.4
  • 22
    • 17644366769 scopus 로고    scopus 로고
    • Surfactant solubility and aggregate orientation in hydrofluoroalkanes
    • DOI 10.1016/j.ijpharm.2005.01.027
    • Ridder K. B., Davies-Cutting C. J., Kellaway I. W., Surfactant solubility and aggregate orientation in hydrofluoroalkanes. International Journal of Pharmaceutics 2005 295 1-2 57 65 2-s2.0-17644366769 10.1016/j.ijpharm.2005.01. 027 (Pubitemid 40558789)
    • (2005) International Journal of Pharmaceutics , vol.295 , Issue.1-2 , pp. 57-65
    • Ridder, K.B.1    Davies-Cutting, C.J.2    Kellaway, I.W.3
  • 23
    • 0023859215 scopus 로고
    • Comparison of output particle size distributions from pressurized aerosols formulated as solutions or suspensions
    • 2-s2.0-0023859215
    • Dalby R. N., Byron P. R., Comparison of output particle size distributions from pressurized aerosols formulated as solutions or suspensions. Pharmaceutical Research 1988 5 1 36 39 2-s2.0-0023859215
    • (1988) Pharmaceutical Research , vol.5 , Issue.1 , pp. 36-39
    • Dalby, R.N.1    Byron, P.R.2
  • 24
    • 44849090657 scopus 로고    scopus 로고
    • Estimating the number of droplets and drug particles emitted from MDIs
    • 2-s2.0-44849090657 10.1208/s12249-007-9006-8
    • Stein S. W., Estimating the number of droplets and drug particles emitted from MDIs. AAPS PharmSciTech 2008 9 1 112 115 2-s2.0-44849090657 10.1208/s12249-007-9006-8
    • (2008) AAPS PharmSciTech , vol.9 , Issue.1 , pp. 112-115
    • Stein, S.W.1
  • 25
    • 41349119146 scopus 로고    scopus 로고
    • Aiming for a moving target: Challenges with impactor measurements of MDI aerosols
    • 2-s2.0-41349119146 10.1016/j.ijpharm.2007.11.047
    • Stein S. W., Aiming for a moving target: challenges with impactor measurements of MDI aerosols. International Journal of Pharmaceutics 2008 355 1-2 53 61 2-s2.0-41349119146 10.1016/j.ijpharm.2007.11.047
    • (2008) International Journal of Pharmaceutics , vol.355 , Issue.1-2 , pp. 53-61
    • Stein, S.W.1
  • 26
    • 3843075402 scopus 로고    scopus 로고
    • A theoretical and experimental analysis of formulation and device parameters affecting solution MDI size distributions
    • DOI 10.1002/jps.20116
    • Stein S. W., Myrdal P. B., A theoretical and experimental analysis of formulation and device parameters affecting solution MDI size distributions. Journal of Pharmaceutical Sciences 2004 93 8 2158 2175 2-s2.0-3843075402 10.1002/jps.20116 (Pubitemid 39045494)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.8 , pp. 2158-2175
    • Stein, S.W.1    Myrdal, P.B.2
  • 27
    • 0032790249 scopus 로고    scopus 로고
    • Size distribution measurements of metered dose inhalers using Andersen Mark II cascade impactors
    • DOI 10.1016/S0378-5173(99)00136-2, PII S0378517399001362
    • Stephen W. S., Size distribution measurements of metered dose inhalers using Andersen Mark II cascade impactors. International Journal of Pharmaceutics 1999 186 1 43 52 2-s2.0-0032790249 10.1016/S0378-5173(99)00136-2 (Pubitemid 29397521)
    • (1999) International Journal of Pharmaceutics , vol.186 , Issue.1 , pp. 43-52
    • Stein, S.W.1
  • 28
    • 0032764740 scopus 로고    scopus 로고
    • A new method to evaluate plume characteristics of hydrofluoroalkane and chlorofluorocarbon metered dose inhalers
    • DOI 10.1016/S0378-5173(99)00133-7, PII S0378517399001337
    • Gabrio B. J., Stein S. W., Velasquez D. J., A new method to evaluate plume characteristics of hydrofluoroalkane and chlorofluorocarbon metered dose inhalers. International Journal of Pharmaceutics 1999 186 1 3 12 2-s2.0-0032764740 10.1016/S0378-5173(99)00133-7 (Pubitemid 29397518)
    • (1999) International Journal of Pharmaceutics , vol.186 , Issue.1 , pp. 3-12
    • Gabrio, B.J.1    Stein, S.W.2    Velasquez, D.J.3
  • 29
    • 34548567783 scopus 로고    scopus 로고
    • The relative influence of atomization and evaporation on metered dose inhaler drug delivery efficiency
    • 2-s2.0-34548567783 10.1080/02786820600612268
    • Stein S. W., Myrdal P. B., The relative influence of atomization and evaporation on metered dose inhaler drug delivery efficiency. Aerosol Science and Technology 2006 40 5 335 347 2-s2.0-34548567783 10.1080/02786820600612268
    • (2006) Aerosol Science and Technology , vol.40 , Issue.5 , pp. 335-347
    • Stein, S.W.1    Myrdal, P.B.2
  • 30
    • 0037027831 scopus 로고    scopus 로고
    • Characterization of inhalation aerosols: A critical evaluation of cascade impactor analysis and laser diffraction technique
    • DOI 10.1016/S0378-5173(02)00526-4, PII S0378517302005264
    • de Boer A. H., Gjaltema D., Hagedoorn P., Frijlink H. W., Characterization of inhalation aerosols: a critical evaluation of cascade impactor analysis and laser diffraction technique. International Journal of Pharmaceutics 2002 249 1-2 219 231 2-s2.0-0037027831 10.1016/S0378-5173(02) 00526-4 (Pubitemid 35333448)
    • (2002) International Journal of Pharmaceutics , vol.249 , Issue.1-2 , pp. 219-231
    • De Boer, A.H.1    Gjaltema, D.2    Hagedoorn, P.3    Frijlink, H.W.4
  • 31
    • 1242343613 scopus 로고    scopus 로고
    • Entry Port Selection for Detecting Particle Size Differences in Metered Dose Inhaler Formulations Using Cascade Impaction
    • DOI 10.1081/DDC-120027514
    • Naini V., Chaudhry S., Berry J., Sharpe S., Hart J., Sequeira J., Entry port selection for detecting particle size differences in metered dose inhaler formulations using cascade impaction. Drug Development and Industrial Pharmacy 2004 30 1 75 82 2-s2.0-1242343613 10.1081/DDC-120027514 (Pubitemid 38240478)
    • (2004) Drug Development and Industrial Pharmacy , vol.30 , Issue.1 , pp. 75-82
    • Naini, V.1    Chaudhry, S.2    Berry, J.3    Sharpe, S.4    Hart, J.5    Sequeira, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.