The airway microbiome and disease

Chest

Volumn 144, Issue 2, 2013, Pages 632-637

  Marsland, Benjamin J ^a   Yadava, Koshika ^a   Nicod, Laurent P ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AIRWAY MICROBIOME; ALLERGIC AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL STRAIN; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYSTIC FIBROSIS; ENTERITIS; FUNCTIONAL ASSESSMENT; HUMAN; IMMUNE DEFICIENCY; IMMUNOCOMPETENT CELL; INFLUENZA; INTESTINE FLORA; LOWER RESPIRATORY TRACT; LUNG DISEASE; MICROBIAL ACTIVITY; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; MICROBIOME; NONHUMAN; PHYLUM; PRIORITY JOURNAL; PROTEOBACTERIA; REGULATORY T LYMPHOCYTE; SYMBIOSIS; UPPER RESPIRATORY TRACT;

EID: 84881535116     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.12-2854     Document Type: Article

References (29)

1. Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science. 2012; 336 (6086): 1268-1273.
2. Xavier RJ, Podolsky DK. Unravelling the pathogenesis of infl am matory bowel disease. Nature. 2007; 448(7152): 427-434.
3. Tilg H, Kaser A. Gut microbiome, obesity, and metabolic dysfunction. J Clin Invest. 2011; 121 (6): 2126-2132.
4. Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 2012; 486 (7402): 207-214.
5. Hilty M, Burke C, Pedro H, et al. Disordered microbial communities in asthmatic airways. PLoS ONE. 2010; 5 (1): e8578.
6. Mallia P, Footitt J, Sotero R, et al. Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012; 186 (11) 1117-1124.
7. Charlson ES, Bittinger K, Haas AR, et al. Topographical continuity of bacterial populations in the healthy human respiratory tract. Am J Respir Crit Care Med. 2011; 184 (8): 957-963.
8. Marri PR, Stern DA, Wright AL, et al. Asthma-associated differences in microbial composition of induced sputum. J Allergy Clin Immunol. 2013; 131 (2): 346-352.
9. Blainey PC, Milla CE, Cornfield DN, et al. Quantitative analysis of the human airway microbial ecology reveals a pervasive signature for cystic fi brosis. Sci Transl Med. 2012; 4(153): 153ra130
10. Erb-Downward JR, Thompson DL, Han MK, et al. Analysis of the lung microbiome in the "healthy" smoker and in COPD. PLoS ONE. 2011; 6 (2): e16384.
11. Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human infl ammatory bowel diseases. Proc Natl Acad Sci U S A. 2007; 104 (34): 13780-13785.
12. Ott SJ, Musfeldt M, Wenderoth DF, et al. Reduction in diversity of the colonic mucosa associated bacterial microfl ora in patients with active infl ammatory bowel disease. Gut. 2004; 53 (5): 685-693.
13. Sze MA, Dimitriu PA, Hayashi S, et al. The lung tissue microbiome in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012; 185 (10): 1073-1080.
14. Charlson ES, Diamond JM, Bittinger K, et al. Lung-enriched organisms and aberrant bacterial and fungal respiratory microbiota after lung transplant. Am J Respir Crit Care Med. 2012; 186 (6): 536-545.
15. Noverr MC, Falkowski NR, McDonald RA, McKenzie AN, Huffnagle GB. Development of allergic airway disease in mice following antibiotic therapy and fungal microbiota increase: role of host genetics, antigen, and interleukin-13. Infect Immun. 2005; 73 (1): 30-38.
16. Noverr MC, Noggle RM, Toews GB, Huffnagle GB. Role of antibiotics and fungal microbiota in driving pulmonary allergic responses. Infect Immun. 2004; 72 (9): 4996-5003.
17. Herbst T, Sichelstiel A, Schär C, et al. Dysregulation of allergic airway infl ammation in the absence of microbial colonization. Am J Respir Crit Care Med. 2011; 184 (2): 198-205.
18. Abt MC, Osborne LC, Monticelli LA, et al. Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity. 2012; 37 (1): 158-170.
19. Olszak T, An D, Zeissig S, et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science. 2012; 336 (6080): 489-493.
20. Forsythe P, Inman MD, Bienenstock J. Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. Am J Respir Crit Care Med. 2007; 175 (6): 561-569.
21. Karimi K, Inman MD, Bienenstock J, Forsythe P. Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice. Am J Respir Crit Care Med. 2009; 179 (3): 186-193.
22. Nembrini C, Sichelstiel A, Kisielow J, Kurrer M, Kopf M, Marsland BJ. Bacterial-induced protection against allergic infl ammation through a multicomponent immunoregulatory mechanism. Thorax. 2011; 66 (9): 755-763.
23. Larsen JM, Steen-Jensen DB, Laursen JM, et al. Divergent pro-infl ammatory profi le of human dendritic cells in response to commensal and pathogenic bacteria associated with the airway microbiota. PLoS ONE. 2012; 7 (2): e31976.
24. Round JL, Mazmanian SK. Inducible Foxp3 1 regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci U S A. 2010; 107 (27): 12204-12209.
25. Naik S, Bouladoux N, Wilhelm C, et al. Compartmentalized control of skin immunity by resident commensals. Science. 2012; 337 (6098): 1115-1119.
26. Feleszko W, Jaworska J, Rha RD, et al. Probiotic-induced suppression of allergic sensitization and airway infl ammation is associated with an increase of T regulatory-dependent mechanisms in a murine model of asthma. Clin Exp Allergy. 2007; 37 (4): 498-505.
27. Forsythe P. Probiotics and lung diseases. Chest. 2011; 139(4): 901-908.
28. Vliagoftis H, Kouranos VD, Betsi GI, Falagas ME. Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials. Ann Allergy Asthma Immunol. 2008; 101 (6): 570-579.
29. Madan JC, Koestler DC, Stanton BA, et al. Serial analysis of the gut and respiratory microbiome in cystic fi brosis in infancy: interaction between intestinal and respiratory tracts and impact of nutritional exposures. MBio. 2012; 3(4): e00251-12.