Carotenoids, versatile components of oxygenic photosynthesis

Progress in Lipid Research

Volumn 52, Issue 4, 2013, Pages 539-561

  Domonkos, Ildikó ^a   Kis, Mihály ^a   Gombos, Zoltán ^a   Ughy, Bettina ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Carotenoid synthesis; Carotenoid lipid interaction; Membrane structure; NPQ; OCP; Photosynthesis

Indexed keywords

ASTAXANTHIN; BETA CAROTENE; CANTHAXANTHIN; CAROTENOID; CHLOROPHYLL A; CHLOROPHYLL C; DIADINOXANTHIN; DIATOXANTHINE; ECHINENONE; FUCOXANTHIN; LYCOPENE; MYXOXANTHOPHYLL; ORANGE CAROTENOID PROTEIN; REACTIVE OXYGEN METABOLITE; SYNECHOXANTHYN; UNCLASSIFIED DRUG; VIOLAXANTHIN; XANTHOPHYLL; ZEAXANTHIN;

ARABIDOPSIS; BIOLOGICAL FUNCTIONS; BIOSYNTHESIS; BROWN ALGA; CHEMICAL COMPOSITION; CHLAMYDOMONAS REINHARDTII; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DEFENSE MECHANISM; DIATOM; DIFFERENTIAL SCANNING CALORIMETRY; INFRARED SPECTROSCOPY; LIGHT HARVESTING SYSTEM; METABOLIC PARAMETERS; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; NONHUMAN; NONPHOTOCHEMICAL QUENCHING; OXIDATIVE STRESS; PHOTOSYSTEM II; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; STRESS; SYNECHOCYSTIS; VISCOSITY; X RAY CRYSTALLOGRAPHY;

CYANOBACTERIA;

(E)-1-HYDROXY-2-METHYL-2-BUTENYL DIPHOSPHATE; 1-DEOXY-D-XYLULOSE 5-PHOSPHATE; 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTO-ISOMERASE; 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE; 15-CIS-Ζ-CAROTENE ISOMERASE; 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE; 2′-O-GLYCOSYLTRANSFERASE; 4-(CITIDINE 5′-DIPHOSPHO)-2-C-METHYL-D-ERYTHRITOL; AACT; ACETOACETYL-COA THIOLASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADP; ALLOPHYCOCYANIN; APC; ATP; BACTERIAL TYPE CAROTENE ISOMERASE; BACTERIOCHLOROPHYLL; BCHL; C-18 HYDROXYLASE; CAR; CAROTENE Β-HYDROXYLASE; CAROTENE Β-KETOLASE; CAROTENOID; CAROTENOID SYNTHESIS; CAROTENOID-LIPID INTERACTION; CDP-ME2P; CHL; CHLOROPHYLL; CHLOROPHYLL-PROTEIN COMPLEX 43; CHLOROPHYLL-PROTEIN COMPLEX 47; CHYΒ; CHYΕ; CIS-TO-TRANS CAROTENOID ISOMERASE; CMP; CP43; CP43-LESS CP47-CONTAINING REACTION CENTER OF PSII; CP47; CRTB; CRTH; CRTI; CRTISO; CRTL; CRTO; CRTP; CRTQ; CRTR; CRTW; CRUA; CRUE; CRUF; CRUG; CRUH; CRUP; CTP; CYTIDINE MONOPHOSPHATE; CYTIDINE TRIPHOSPHATE; D-GLYCERALDEHYDE 3-PHOSPHATE; DDE; DDX; DEP; DIADINOXANTHIN; DIADINOXANTHIN DE-EPOXIDASE; DIATOXANTHIN EPOXIDASE; DIATOXATHIN; DIMETHYLALLYL DIPHOSPHATE; DMAPP; DTX; DXP; DXR; DXS; EF-G; ELONGATION FACTOR G; GAP; GERANYLGERANYL DIPHOSPHATE; GGPP; HMBDP; HMG-COA; HMG-COA REDUCTASE; HMGR; IPP; ISOPENTENYL DIPHOSPHATE; LCYΒ; LCYΕ; LHC; LHCI; LHCII; LHCSR; LIGHT HARVESTING COMPLEX; LIGHT HARVESTING COMPLEX OF PSI; LIGHT HARVESTING COMPLEX OF PSII; LIGHT HARVESTING STRESS RESPONSE PROTEIN; LYCOPENE CYCLASE; LYCOPENE Β-CYCLASE; LYCOPENE Ε-CYCLASE; MECDP; MEMBRANE STRUCTURE; MEP; METHYLERYTHRITOL PHOSPHATE; MEVALONIC ACID; MVA; NADP(+); NADPH; NEOXANTHIN SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NON-PHOTOCHEMICAL QUENCHING; NPQ; NSY; OCP; ORANGE CAROTENOID PROTEIN; PCP; PDS; PERIDININ-CHL A PROTEIN; PHOTOSYNTHESIS; PHOTOSYSTEM I; PHOTOSYSTEM II; PHYTOENE DESATURASE; PHYTOENE SYNTHASE; PSI; PSII; PSY; RC47; REACTIVE OXYGEN SPECIES; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ROS; VDE; VIOLAXANTHIN DE-EPOXIDASE; Z-ISO; ZDS; ZEAXANTHIN EPOXIDASE; ZEP; Β-CAROTENE DESATURASE/METHYLTRANSFERASE; Β-HYDROXY-Β-METHYLGLUTARYL-COA; Β-HYDROXYLASE; Γ-CAROTENE 1′-HYDROXYLASE; Ε-HYDROXYLASE; Ζ-CAROTENE DESATURASE;

CAROTENOIDS; CYANOBACTERIA; OXYGEN; PHOTOSYNTHETIC REACTION CENTER COMPLEX PROTEINS; PROTECTIVE AGENTS; XANTHOPHYLLS;

EID: 84881523577     PISSN: 01637827     EISSN: 18732194     Source Type: Journal    
DOI: 10.1016/j.plipres.2013.07.001     Document Type: Review

References (264)

1. L. Ruzicka The isoprene rule and the biogenesis of terpenic compounds Experientia 9 1953 357 367
2. A. Disch, J. Schwender, C. Müller, H.K. Lichtenthaler, and M. Rohmer Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714 Biochem J 333 1998 381 388
3. A. Hemmerlin, J.L. Harwood, and T.J. Bach A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis? Prog Lipid Res 51 2012 95 148
4. H.K. Lichtenthaler The 1-deoxy-d-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants Annu Rev Plant Physiol Plant Mol Biol 50 1999 47 65
5. M. Lohr, J. Schwender, and J.E.W. Polle Isoprenoid biosynthesis in eukaryotic phototrophs: a spotlight on algae Plant Sci 185 2012 9 22
6. M. Rodríguez-Concepción Supply of precursors for carotenoid biosynthesis in plants Arch Biochem Biophys 504 2010 118 122
7. D. Tritsch, A. Hemmerlin, T.J. Bach, and M. Rohmer Plant isoprenoid biosynthesis via the MEP pathway: in vivo IPP/DMAPP ratio produced by (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures FEBS Lett 584 2010 129 134
8. W. Eisenreich, A. Bacher, D. Arigoni, and F. Rohdich Biosynthesis of isoprenoids via the non-mevalonate pathway Cell Mol Life Sci 61 2004 1401 1426
9. T. Grawert, M. Groll, F. Rohdich, A. Bacher, and W. Eisenreich Biochemistry of the non-mevalonate isoprenoid pathway Cell Mol Life Sci 68 2011 3797 3814
10. W.N. Hunter The non-mevalonate pathway of isoprenoid precursor biosynthesis J Biol Chem 282 2007 21573 21577
11. T. Kuzuyama, and H. Seto Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis Proc J Acad B Phys Biol Sci 88 2012 41 52
12. M. Rohmer From molecular fossils of bacterial hopanoids to the formation of isoprene units: discovery and elucidation of the methylerythritol phosphate pathway Lipids 43 2008 1095 1107
13. M. Rodríguez-Concepción, and A. Boronat Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics Plant Physiol 130 2002 1079 1089
14. E. Cordoba, M. Salmi, and P. León Unravelling the regulatory mechanisms that modulate the MEP pathway in higher plants J Exp Bot 60 2009 2933 2943
15. N. Dudareva, S. Andersson, I. Orlova, N. Gatto, M. Reichelt, and D. Rhodes The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers Proc Natl Acad Sci USA 102 2005 933 938
16. U. Flores-Pérez, J. Pérez-Gila, M. Closa, L.P. Wright, P. Botella-Pavía, and M.A. Phillips Pleiotropic regulatory locus 1 (Prl1) integrates the regulation of sugar responses with isoprenoid metabolism in Arabidopsis Mol Plant 3 2010 101 112
17. A. Hemmerlin, J.F. Hoeffler, O. Meyer, D. Tritsch, I.A. Kagan, and C. Grosdemange-Billiard Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in Tobacco Bright Yellow-2 cells J Biol Chem 278 2003 26666 26676
18. H. Kasahara, A. Hanada, T. Kuzuyama, M. Takagi, Y. Kamiya, and S. Yamaguchi Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis J Biol Chem 277 2002 45188 45194
19. N. Nagata, M. Suzuki, S. Yoshida, and T. Muranaka Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway Planta 216 2002 345 350
20. K. Okada, H. Kasahara, S. Yamaguchi, H. Kawaide, Y. Kamiya, and H. Nojiri Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis Plant Cell Physiol 49 2008 604 616
21. H.M. Miziorko Enzymes of the mevalonate pathway of isoprenoid biosynthesis Arch Biochem Biophys 505 2011 131 143
22. N. Campos, and A. Boronat Targeting and topology in the membrane of plant 3-hydroxy-3-methylglutaryl coenzyme a reductase Plant Cell 7 1995 2163 2174
23. P. Leivar, V.M. Gonzalez, S. Castel, R.N. Trelease, C. Lopez-Iglesias, and M. Arró Subcellular localization of Arabidopsis 3-hydroxy-3- methylglutaryl-coenzyme A reductase Plant Physiol 137 2005 57 69
24. P. Leivar, M. Antolín-Llovera, S. Ferrero, M. Closa, M. Arró, and A. Ferrer Multilevel control of Arabidopsis 3-hydroxy-3-methylglutaryl coenzyme A reductase by protein phosphatase 2A Plant Cell 23 2011 1494 1511
25. M. Sapir-Mir, A. Mett, E. Belausov, S. Tal-Meshulam, A. Frydman, and D. Gidoni Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes Plant Physiol 148 2008 1219 1228
26. A.J. Simkin, G. Guirimand, N. Papon, V. Courdavault, I. Thabet, and O. Ginis Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta Planta 234 2011 903 914
27. C.D. Poulter, P.L. Wiggins, and A.T. Le Farnesylpyrophosphate synthetase - a stepwise mechanism for the 1′-4 condensation reaction J Am Chem Soc 103 1981 3926 3927
28. F. Bouvier, A. Rahier, and B. Camara Biogenesis, molecular regulation and function of plant isoprenoids Prog Lipid Res 44 2005 357 429
29. B.A. Kellogg, and C.D. Poulter Chain elongation in the isoprenoid biosynthetic pathway Curr Opin Chem Biol 1 1997 570 578
30. N. Misawa, M.R. Truesdale, G. Sandmann, P.D. Fraser, C. Bird, and W. Schuch Expression of a tomato cDNA coding for phytoene synthase in Escherichia coli, phytoene formation in vivo and in vitro, and functional analysis of the various truncated gene products J Biochem (Tokyo) 116 1994 980 985
31. G. Sandmann Carotenoid biosynthesis in microorganisms and plants Eur J Biochem 223 1994 7 24
32. G. Sandmann Evolution of carotene desaturation: the complication of a simple pathway Arch Biochem Biophys 483 2009 169 174
33. S. Steiger, Y. Jackisch, and G. Sandmann Carotenoid biosynthesis in Gloeobacter violaceus PCC4721 involves a single crtI-type phytoene desaturase instead of typical cyanobacterial enzymes Arch Microbiol 184 2005 207 214
34. T. Tsuchiya, S. Takaichi, N. Misawa, T. Maoka, H. Miyashita, and M. Mimuro The cyanobacterium Gloeobacter violaceus PCC 7421 uses bacterial-type phytoene desaturase in carotenoid biosynthesis FEBS Lett 579 2005 2125 2129
35. J. Breitenbach, and G. Sandmann ζ-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene Planta 220 2005 785 793
36. Y. Chen, F.Q. Li, and E.T. Wurtzel Isolation and characterization of the Z-ISO gene encoding a missing component of carotenoid biosynthesis in plants Plant Physiol 153 2010 66 79
37. F.Q. Li, C. Murillo, and E.T. Wurtzel Maize Y9 encodes a product essential for 15-cis-ζ-carotene isomerization Plant Physiol 144 2007 1181 1189
38. T. Isaacson, G. Ronen, D. Zamir, and J. Hirschberg Cloning of tangerine from tomato reveals a carotenoid isomerase essential for the production of β-carotene and xanthophylls in plants Plant Cell 14 2002 333 342
39. K. Masamoto, H. Wada, T. Kaneko, and S. Takaichi Identification of a gene required for cis-to-trans carotene isomerization in carotenogenesis of the cyanobacterium Synechocystis sp. PCC 6803 Plant Cell Physiol 42 2001 1398 1402
40. H. Park, S.S. Kreunen, A.J. Cuttriss, D. DellaPenna, and B.J. Pogson Identification of the carotenoid isomerase provides insight into carotenoid biosynthesis, prolamellar body formation, and photomorphogenesis Plant Cell 14 2002 321 332
41. Q. Yu, S. Ghisla, J. Hirschberg, V. Mann, and P. Beyer Plant carotene cis-trans isomerase CRTISO: a new member of the FAD(RED)-dependent flavoproteins catalyzing non-redox reactions J Biol Chem 286 2011 8666 8676
42. H. Linden, A. Vioque, and G. Sandmann Isolation of a carotenoid biosynthesis gene coding for ζ-carotene desaturase from Anabaena PCC7120 by heterologous complementation FEMS Microbiol Lett 106 1993 99 104
43. H. Linden, N. Misawa, T. Saito, and G. Sandmann A novel carotenoid biosynthesis gene coding for ζ-carotene desaturase - functional expression, sequence and phylogenetic origin Plant Mol Biol 24 1994 369 379
44. I. Pecker, R. Gabbay, F.X. Cunningham Jr., and J. Hirschberg Cloning and characterization of the cDNA for lycopene β-cyclase from tomato reveals decrease in its expression during fruit ripening Plant Mol Biol 30 1996 807 819
45. F.X. Cunningham Jr., and E. Gantt One ring or two? Determination of ring number in carotenoids by lycopene ε-cyclases Proc Natl Acad Sci USA 98 2001 2905 2910
46. J. Kim, and D. DellaPenna Defining the primary route for lutein synthesis in plants: the role of Arabidopsis carotenoid β-ring hydroxylase CYP97A3 Proc Natl Acad Sci USA 103 2006 3474 3479
47. S. Takaichi, and M. Mochimaru Carotenoids and carotenogenesis in cyanobacteria: unique ketocarotenoids and carotenoid glycosides Cell Mol Life Sci 64 2007 2607 2619
48. S. Takaichi Carotenoids in algae: distributions, biosyntheses and functions Mar Drugs 9 2011 1101 1118
49. S. Takaichi, M. Mochimaru, H. Uchida, A. Murakami, E. Hirose, and T. Maoka Opposite chilarity of β-carotene in unusual cyanobacteria with unique chlorophylls. Acaryochloris and Prochlorococcus Plant Cell Physiol 53 2012 1881 1888
50. J.A. Maresca, J.E. Graham, M. Wu, J.A. Eisen, and D.A. Bryant Identification of a fourth family of lycopene cyclases in photosynthetic bacteria Proc Natl Acad Sci USA 104 2007 11784 11789
51. R. Goss, and T. Jakob Regulation and function of xanthophyll cycle-dependent photoprotection in algae Photosynth Res 106 2010 103 122
52. M. Bertrand Carotenoid biosynthesis in diatoms Photosynth Res 106 2010 89 102
53. M. Dambek, U. Eilers, J. Breitenbach, S. Steiger, C. Büchel, and G. Sandmann Biosynthesis of fucoxanthin and diadinoxanthin and function of initial pathway genes in Phaeodactylum tricornutum J Exp Bot 63 2012 5607 5612
54. S. Takaichi, and M. Mimuro Distribution and geometric isomerism of neoxanthin in oxygenic phototrophs: 9′-cis, a sole molecular form Plant Cell Physiol 39 1998 968 977
55. T. Makino, H. Harada, H. Ikenaga, S. Matsuda, S. Takaichi, and K. Shindo Characterization of cyanobacterial carotenoid ketolase CrtW and hydroxylase CrtR by complementation analysis inEscherichia coli Plant Cell Physiol 49 2008 1867 1878
56. K. Masamoto, N. Misawa, T. Kaneko, R. Kikuno, and H. Toh β-Carotene hydroxylase gene from the cyanobacterium Synechocystis sp. PCC6803 Plant Cell Physiol 39 1998 560 564
57. M. Iwai, T. Maoka, M. Ikeuchi, and S. Takaichi 2,2-Hydroxylase (CrtG) is involved in carotenogenesis of both nostoxanthin and 2-hydroxymyxol 2-fucoside in Thermosynechococcus elongatus strain BP-1 Plant Cell Physiol 49 2008 1678 1687
58. M. Mochimaru, H. Masukawa, and S. Takaichi The cyanobacterium Anabaena sp. PCC 7120 has two distinct β-carotene ketolases: CrtO for echinenone and CrtW for ketomyxol synthesis FEBS Lett 579 2005 6111 6114
59. B. FernandezGonzalez, G. Sandmann, and A. Vioque A new type of asymmetrically acting β-carotene ketolase is required for the synthesis of echinenone in the cyanobacterium Synechocystis sp. PCC 6803 J Biol Chem 272 1997 9728 9733
60. J. Breitenbach, T. Gerjets, and G. Sandmann Catalytic properties and reaction mechanism of the CrtO carotenoid ketolase from the cyanobacterium Synechocystis sp. PCC 6803 Arch Biochem Biophys 529 2013 86 91
61. S. Steiger, and G. Sandmann Cloning of two carotenoid ketolase genes from Nostoc punctiforme for the heterologous production of canthaxanthin and astaxanthin Biotechnol Lett 26 2004 813 817
62. R.T. Lorenz, and G.R. Cysewski Commercial potential for Haematococcus microalgae as a natural source of astaxanthin Trends Biotechnol 18 2000 160 167
63. E. Rodrigues, L.R.B. Mariutti, and A.Z. Mercadante Scavenging capacity of marine carotenoids against reactive oxygen and nitrogen species in a membrane-mimicking system Mar Drugs 10 2012 1784 1798
64. Y. Lemoine, and B. Schoefs Secondary ketocarotenoid astaxanthin biosynthesis in algae: a multifunctional response to stress Photosynth Res 106 2010 155 177
65. R. Vidhyavathi, L. Venkatachalam, R. Sarada, and G.A. Ravishankar Regulation of carotenoid biosynthetic genes expression and carotenoid accumulation in the green alga Haematococcus pluvialis under nutrient stress conditions J Exp Bot 59 2008 1409 1418
66. S. Takaichi, T. Maoka, and K. Masamoto Myxoxanthophyll in Synechocystis sp. PCC 6803 is myxol 2′-dimethyl-fucoside, (3R,2′ S)-myxol 2′-(2,4-di-O-methyl-alpha-l-fucoside), not rhamnoside Plant Cell Physiol 42 2001 756 762
67. S. Takaichi, M. Mochimaru, and T. Maoka Presence of free myxol and 4-hydroxymyxol and absence of myxol glycosides in Anabaena variabilis ATCC 29413, and proposal of a biosynthetic pathway of carotenoids Plant Cell Physiol 47 2006 211 216
68. S. Takaichi, T. Maoka, and M. Mochimaru Unique carotenoids in the terrestrial cyanobacterium Nostoc commune NIES-24: 2-hydroxymyxol 2′-fucoside, nostoxanthin and canthaxanthin Curr Microbiol 59 2009 413 419
69. S. Takaichi, M. Mochimaru, T. Maoka, and H. Katoh Myxol and 4-ketomyxol 2′-fucosides, not rhamnosides, from Anabaena sp. PCC 7120 and Nostoc punctiforme PCC 73102, and proposal for the biosynthetic pathway of carotenoids Plant Cell Physiol 46 2005 497 504
70. J.E. Graham, and D.A. Bryant The biosynthetic pathway for myxol-2′ fucoside (myxoxanthophyll) in the cyanobacterium Synechococcus sp. strain PCC 7002 (vol 191, pg 3292, 2009) J Bacteriol 191 2009 4485
71. D. Lagarde, and W. Vermaas The zeaxanthin biosynthesis enzyme β-carotene hydroxylase is involved in myxoxanthophyll synthesis in Synechocystis sp. PCC 6803 FEBS Lett 454 1999 247 251
72. J.E. Graham, and D.A. Bryant The biosynthetic pathway for synechoxanthin, an aromatic carotenoid synthesized by the euryhaline, unicellular cyanobacterium Synechococcus sp. Strain PCC 7002 J Bacteriol 190 2008 7966 7974
73. G. Farre, G. Sanahuja, S. Naqvi, C. Bai, T. Capell, and C.F. Zhu Travel advice on the road to carotenoids in plants Plant Sci 179 2010 28 48
74. M. Mochimaru, H. Masukawa, T. Maoka, H.E. Mohamed, W.F.J. Vermaas, and S. Takaichi Substrate specificities and availability of fucosyltransferase and β-carotene hydroxylase for myxol 2′-Fucoside synthesis in Anabaena sp. strain PCC 7120 compared with Synechocystis sp. strain PCC 6803 J Bacteriol 190 2008 6726 6733
75. L. Schäfer, A. Vioque, and G. Sandmann Functional in situ evaluation of photo synthesis-protecting carotenoids in mutants of the cyanobacterium Synechocystis PCC6803 J Photochem Photobiol B Biol 78 2005 195 201
76. J.A. Bautista, C.A. Tracewell, E. Schlodder, F.X. Cunningham Jr., G.W. Brudvig, and B.A. Diner Construction and characterization of genetically modified Synechocystis sp. PCC 6803 Photosystem II core complexes containing carotenoids with shorter π-conjugation than β-carotene J Biol Chem 280 2005 38839 38850
77. H.E. Mohamed, A.M.L. van de Meene, R.W. Roberson, and W.F.J. Vermaas Myxoxanthophyll is required for normal cell wall structure and thylakoid organization in the cyanobacterium, Synechocystis sp. strain PCC 6803 J Bacteriol 187 2005 6883 6892
78. O. Sozer, J. Komenda, B. Ughy, I. Domonkos, H. Laczkó-Dobos, and P. Malec Involvement of carotenoids in the synthesis and assembly of protein subunits of photosynthetic reaction centers of Synechocystis sp. PCC 6803 Plant Cell Physiol 51 2010 823 835
79. G. Sandmann Light-dependent switch from formation of poly-cis carotenes to all-trans carotenoids in the Scenedesmus mutant C-6D Arch Microbiol 155 1991 229 233
80. R. Powls, and G. Britton Series of mutant strains of Scenedesmus obliquus with abnormal carotenoid compositions Arch Microbiol 113 1977 275 280
81. S. Römer, H. Senger, and N.I. Bishop Characterization of the carotenoidless strain of Scenedesmus obliquus, mutant C-6E, a living photosystem I model Bot Acta 108 1995 80 86
82. S.S. McCarthy, M.C. Kobayashi, and K.K. Niyogi White mutants of Chlamydomonas reinhardtii are defective in phytoene synthase Genetics 168 2004 1249 1257
83. K.K. Niyogi, O. Björkman, and A.R. Grossman Chlamydomonas xanthophyll cycle mutants identified by video imaging of chlorophyll fluorescence quenching Plant Cell 9 1997 1369 1380
84. E.S. Jin, B. Feth, and A. Melis A mutant of the green alga Dunaliella salina constitutively accumulates zeaxanthin under all growth conditions Biotechnol Bioeng 81 2003 115 124
85. A.M.L. van de Meene, M.F. Hohmann-Marriott, W.F.J. Vermaas, and R.W. Roberson The three-dimensional structure of the cyanobacterium Synechocystis sp. PCC 6803 Arch Microbiol 184 2006 259 270
86. A.M.T. van de Meene, W.P. Sharp, J.H. McDaniel, H. Friedrich, W.F.J. Vermaas, and R.W. Roberson Gross morphological changes in thylakoid membrane structure are associated with photosystem I deletion in Synechocystis sp. PCC 6803 Biochim Biophys Acta Biomembr 1818 2012 1427 1434
87. F. Nilsson, D.J. Simpson, C. Jansson, and B. Andersson Ultrastructural and biochemical characterization of a Synechocystis 6803 mutant with inactivated psbA genes Arch Biochem Biophys 295 1992 340 347
88. W.I. Gruszecki, and K. Strzalka Carotenoids as modulators of lipid membrane physical properties Biochim Biophys Acta Mol B Dis 1740 2005 108 115
89. J. Widomska, A. Kostecka-Gugala, D. Latowski, W.I. Gruszecki, and K. Strzalka Calorimetric studies of the effect of cis-carotenoids on the thermotropic phase behavior of phosphatidylcholine bilayers Biophys Chem 140 2009 108 114
90. W.I. Gruszecki Carotenoids in membranes H.A. Frank, A.J. Young, G. Britton, R.J. Cogdell, The photochemistry of carotenoids 1999 Kluwer Academic Publishers Dordrecht, The Neatherlands 363 379
91. 1H NMR study of carotenoid-egg phosphatidylcholine liposomes Biochim Biophys Acta Biomembr 1285 1996 167 174
92. K. Gounaris, and J. Barber Monogalactosyldiacylglycerol - the most abundant polar lipid in nature Trends Biochem Sci 8 1983 378 381
93. Z. Gombos, H. Wada, and N. Murata The recovery of photosynthesis from low-temperature photoinhibition is accelerated by the unsaturation of membrane lipids - a mechanism of chilling tolerance Proc Natl Acad Sci USA 91 1994 8787 8791
94. H. Wada, Z. Gombos, and N. Murata Contribution of membrane-lipids to the ability of the photosynthetic machinery to tolerate temperature stress Proc Natl Acad Sci USA 91 1994 4273 4277
95. N.P.A. Huner, B. Elfman, M. Krol, and A. Mcintosh Growth and development at cold-hardening temperatures - chloroplast ultrastructure, pigment content, and composition Can J Bot (french) 62 1984 53 60
96. W.K. Subczynski, E. Markowska, W.I. Gruszecki, and J. Sielewiesiuk Effects of polar carotenoids on dimyristoylphosphatidylcholine membranes - a spin-label study Biochim Biophys Acta 1105 1992 97 108
97. Z. Gombos, H. Wada, E. Hideg, and N. Murata The unsaturation of membrane lipids stabilizes photosynthesis against heat-stress Plant Physiol 104 1994 563 567
98. O. Montero, A. Sánchez-Guijo, L.M. Lubián, and G. Martínez-Rodríguez Changes in membrane lipids and carotenoids during light acclimation in a marine cyanobacterium Synechococcus sp. J Biosci 37 2012 635 645
99. I. Domonkos, P. Malec, A. Sallai, L. Kovács, K. Itoh, and G.Z. Shen Phosphatidylglycerol is essential for oligomerization of photosystem I reaction center Plant Physiol 134 2004 1471 1478
100. I. Domonkos, P. Malec, H. Laczko-Dobos, O. Sozer, K. Klodawska, and H. Wada Phosphatidylglycerol depletion induces an increase in myxoxanthophyll biosynthetic activity in Synechocystis PCC6803 cells Plant Cell Physiol 50 2009 374 382
101. J.E. Sarry, J.L. Montillet, Y. Sauvaire, and M. Havaux The protective function of the xanthophyll cycle in photosynthesis FEBS Lett 353 1994 147 150
102. S. Rottem, and O. Markowitz Carotenoids act as reinforcers of the Acholeplasma laidlawii lipid bilayer J Bacteriol 140 1979 944 948
103. Z. Varkonyi, K. Masamoto, M. Debreczeny, O. Zsiros, B. Ughy, and Z. Gombos Low-temperature-induced accumulation of xanthophylls and its structural consequences in the photosynthetic membranes of the cyanobacterium Cylindrospermopsis raciborskii: an FTIR spectroscopic study Proc Natl Acad Sci USA 99 2002 2410 2415
104. E. Oldfield, M. Meadows, D. Rice, and R. Jacobs Spectroscopic studies of specifically deuterium labeled membrane systems - Nuclear Magnetic-Resonance investigation of effects of cholesterol in model systems Biochemistry (Mosc) 17 1978 2727 2740
105. T. Rog, and M. Pasenkiewicz-Gierula Cholesterol effects on the phosphatidylcholine bilayer nonpolar region: a molecular simulation study Biophys J 81 2001 2190 2202
106. T.P. Trouard, A.A. Nevzorov, T.M. Alam, C. Job, J. Zajicek, and M.F. Brown Influence of cholesterol on dynamics of dimyristoylphosphatidylcholine bilayers as studied by deuterium NMR relaxation J Chem Phys 110 1999 8802 8818
107. D. Marsh, and I.O. Smith Interacting spin labels as probes of molecular separation within phospholipid bilayers Biochem Biophys Res Commun 49 1972 916 922
108. W.K. Subczynski, A. Wisniewska, J.J. Yin, J.S. Hyde, and A. Kusumi Hydrophobic barriers of lipid bilayer membranes formed by reduction of water penetration by alkyl chain unsaturation and cholesterol Biochemistry (Mosc) 33 1994 7670 7681
109. M. Bloom, E. Evans, and O.G. Mouritsen Physical properties of the fluid lipid bilayer component of cell membranes - a perspective Q Rev Biophys 24 1991 293 397
110. W.I. Gruszecki, and K. Strzalka Does the xanthophyll cycle take part in the regulation of fluidity of the thylakoid membrane Biochim Biophys Acta 1060 1991 310 314
111. D. Rengel, A. Díez-Navajas, A. Serna-Rico, P. Veiga, A. Muga, and J.C.G. Milicua Exogenously incorporated ketocarotenoids in large unilamellar vesicles. Protective activity against peroxidation Biochim Biophys Acta Biomembr 1463 2000 179 187
112. A. Sujak Interactions between canthaxanthin and lipid membranes - possible mechanisms of canthaxanthin toxicity Cell Mol Biol Lett 14 2009 395 410
113. S. Steiger, L. Schäfer, and G. Sandmann High-light-dependent upregulation of carotenoids and their antioxidative properties in the cyanobacterium Synechocystis PCC 6803 J Photochem Photobiol B Biol 52 1999 14 18
114. P. Molnar, and J. Szabolcs (Z/E)-photoisomerization of C40-carotenoids by iodine J Chem Soc Perkin Trans 2 1993 261 266
115. A. Guskov, J. Kern, A. Gabdulkhakov, M. Broser, A. Zouni, and W. Saenger Cyanobacterial photosystem II at 2.9-Å resolution and the role of quinones, lipids, channels and chloride Nat Struct Mol Biol 16 2009 334 342
116. M. Broser, A. Gabdulkhakov, J. Kern, A. Guskov, F. Muh, and W. Saenger Crystal structure of monomeric Photosystem II from Thermosynechococcus elongatus at 3.6-Å resolution J Biol Chem 285 2010 26255 26262
117. Y. Umena, K. Kawakami, J.R. Shen, and N. Kamiya Crystal structure of oxygen-evolving photosystem II at a resolution of 1.9 Å Nature 473 2011 U55 U65
118. O. Sozer, M. Kis, Z. Gombos, and B. Ughy Proteins, glycerolipids and carotenoids in the functional photosystem II architecture Front Biosci 16 2011 619 643
119. A. Trebst, and B. Depka Role of carotene in the rapid turnover and assembly of photosystem II in Chlamydomonas reinhardtii FEBS Lett 400 1997 359 362
120. S.O. Wenk, D. Schneider, U. Boronowsky, C. Jäger, C. Klughammer, and F.L. de Weerd Functional implications of pigments bound to a cyanobacterial cytochrome b(6)f complex FEBS J 272 2005 582 592
121. U. Boronowsky, S.O. Wenk, D. Schneider, C. Jäger, and M. Rögner Isolation of membrane protein subunits in their native state: evidence for selective binding of chlorophyll and carotenoid to the b(6) subunit of the cytochrome b(6)f complex Biochim Biophys Acta Bioenerg 1506 2001 55 66
122. 6f complex of oxygenic photosynthesis: tuning the cavity Science 302 2003 1009 1014
123. D. Stroebel, Y. Choquet, J.L. Popot, and D. Picot An atypical haem in the cytochrome b(6)f complex Nature 426 2003 413 418
124. A. Amunts, H. Toporik, A. Borovikova, and N. Nelson Structure determination and improved model of plant photosystem I J Biol Chem 285 2010 3478 3486
125. A. Amunts, O. Drory, and N. Nelson The structure of a plant photosystem I supercomplex at 3.4 angstrom resolution Nature 447 2007 58 63
126. P. Fromme, P. Jordan, and N. Krauss Structure of photosystem I Biochim Biophys Acta Bioenerg 1507 2001 5 31
127. P. Fromme, A. Melkozernov, P. Jordan, and N. Krauss Structure and function of photosystem I: interaction with its soluble electron carriers and external antenna systems FEBS Lett 555 2003 40 44
128. P. Jordan, P. Fromme, H.T. Witt, O. Klukas, W. Saenger, and N. Krauss Three-dimensional structure of cyanobacterial photosystem I at 2.5 Å resolution Nature 411 2001 909 917
129. J.A. Bautista, F. Rappaport, M. Guergova-Kuras, R.O. Cohen, J.H. Golbeck, and J.Y. Wang Biochemical and biophysical characterization of photosystem I from phytoene desaturase and ζ-carotene desaturase deletion mutants of Synechocystis sp. PCC 6803 J Biol Chem 280 2005 20030 20041
130. H. Ishikita, and E.W. Knapp Redox potential of quinones in both electron transfer branches of photosystem I J Biol Chem 278 2003 52002 52011
131. A. Van der Est, A.I. Valieva, Y.E. Kandrashkin, G. Shen, D.A. Bryant, and J.H. Golbeck Removal of PsaF alters forward electron transfer in photosystem I: evidence for fast reoxidation of QK-A in subunit deletion mutants of Synechococcus sp. PCC 7002 Biochemistry (Mosc) 43 2004 1264 1275
132. V.P. Chitnis, and P.R. Chitnis Psal subunit is required for the formation of Photosystem-I trimers in the cyanobacterium Synechocystis sp. PCC-6803 FEBS Lett 336 1993 330 334
133. W.M. Schluchter, G.H. Shen, J.D. Zhao, and D.A. Bryant Characterization of psaI and psaL mutants of Synechococcus sp. strain PCC 7002: a new model for state transitions in cyanobacteria Photochem Photobiol 64 1996 53 66
134. A. Busch, and M. Hippler The structure and function of eukaryotic photosystem I Biochim Biophys Acta Bioenerg 1807 2011 864 877
135. M. Ballottari, C. Govoni, S. Caffarri, and T. Morosinotto Stoichiometry of LHCI antenna polypeptides and characterization of gap and linker pigments in higher plants Photosystem I Eur J Biochem 271 2004 4659 4665
136. R. Croce, T. Morosinotto, S. Castelletti, J. Breton, and R. Bassi The Lhca antenna complexes of higher plants photosystem I Biochim Biophys Acta Bioenerg 1556 2002 29 40
137. R. Croce, M. Mozzo, T. Morosinotto, A. Romeo, R. Hienerwadel, and R. Bassi Singlet and triplet state transitions of carotenoids in the antenna complexes of higher-plant Photosystem I Biochemistry (Mosc) 46 2007 3846 3855
138. Z. Liu, H. Yan, K. Wang, T. Kuang, J. Zhang, and L. Gui Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution Nature 428 2004 287 292
139. E. Formaggio, G. Cinque, and R. Bassi Functional architecture of the major light-harvesting complex from higher plants J Mol Biol 314 2001 1157 1166
140. A. Fiore, L. Dall'Osto, S. Cazzaniga, G. Diretto, G. Giuliano, and R. Bassi A quadruple mutant of Arabidopsis reveals a β-carotene hydroxylation activity for LUT1/CYP97C1 and a regulatory role of xanthophylls on determination of the PSI/PSII ratio BMC Plant Biol 12 2012 50
141. T. Barros, A. Royant, J. Standfuss, A. Dreuw, and W. Kühlbrandt Crystal structure of plant light-harvesting complex shows the active, energy-transmitting state EMBO J 28 2009 298 306
142. N.I. Bishop The β, ε-carotenoid, lutein, is specifically required for the formation of the oligomeric forms of the light harvesting complex in the green alga, Scenedesmus obliquus J Photochem Photobiol B Biol 36 1996 279 283
143. M. Havaux, L. Dall'Osto, S. Cuine, G. Giuliano, and R. Bassi The effect of zeaxanthin as the only xanthophyll on the structure and function of the photosynthetic apparatus in Arabidopsis thaliana J Biol Chem 279 2004 13878 13888
144. I. Heinze, E. Pfundel, M. Huhn, and H. Dau Assembly of light harvesting complexes II(LHC-II) in the absence of lutein - a study on the α-carotenoid-free mutant C-2A′-34 of the green alga Scenedesmus obliquus Biochim Biophys Acta Bioenerg 1320 1997 188 194
145. H. Lokstein, L. Tian, J.E.W. Polle, and D. DellaPenna Xanthophyll biosynthetic mutants of Arabidopsis thaliana: altered nonphotochemical quenching of chlorophyll fluorescence is due to changes in Photosystem II antenna size and stability Biochim Biophys Acta Bioenerg 1553 2002 309 319
146. J.E.W. Polle, K.K. Niyogi, and A. Melis Absence of lutein, violaxanthin and neoxanthin affects the functional chlorophyll antenna size of photosystem-II but not that of photosystem-I in the green alga Chlamydomonas reinhardtii Plant Cell Physiol 42 2001 482 491
147. J. Psencik, T.P. Ikonen, P. Laurinmaki, M.C. Merckel, S.J. Butcher, and R.E. Serimaa Lamellar organization of pigments in chlorosomes, the light harvesting complexes of green photosynthetic bacteria Biophys J 87 2004 1165 1172
148. J. Psencik, J.B. Arellano, T.P. Ikonen, C.M. Borrego, P.A. Laurinmaki, and S.J. Butcher Internal structure of chlorosomes from brown-colored Chlorobium species and the role of carotenoids in their assembly Biophys J 91 2006 1433 1440
149. J. Psencik, A.M. Collins, L. Liljeroos, M. Torkkeli, P. Laurinmaki, and H.M. Ansink Structure of chlorosomes from the green filamentous bacterium Chloroflexus aurantiacus J Bacteriol 191 2009 6701 6708
150. E. Garcia-Mendoza, H. Ocampo-Alvarez, and Govindjee Photoprotection in the brown alga Macrocystis pyrifera: evolutionary implications J Photochem Photobiol B Biol 104 2011 377 385
151. T. Katoh, M. Mimuro, and S. Takaichi Light-harvesting particles isolated from a brown alga, Dictyota dichotoma - a supramolecular assembly of fucoxanthin-chlorophyll-protein complexes Biochim Biophys Acta 976 1989 233 240
152. T. Katoh, and T. Ehara Supramolecular assembly of fucoxanthin- chlorophyll-protein complexes isolated from a brown alga, Petalonia fascia - electron microscopic studies Plant Cell Physiol 31 1990 439 447
153. M. Mimuro, T. Katoh, and H. Kawai Spatial arrangement of pigments and their interaction in the fucoxanthin-chlorophyll a/c protein assembly (Fcpa) isolated from the brown alga Dictyota dichotoma - analysis by means of polarized spectroscopy Biochim Biophys Acta 1015 1990 450 456
154. A. Beer, K. Gundermann, J. Beckmann, and C. Büchel Subunit composition and pigmentation of fucoxanthin-chlorophyll proteins in diatoms: evidence for a subunit involved in diadinoxanthin and diatoxanthin binding Biochemistry (Mosc) 45 2006 13046 13053
155. C. Büchel Fucoxanthin-chlorophyll proteins in diatoms: 18 and 19 kDa subunits assemble into different oligomeric states Biochemistry (Mosc) 42 2003 13027 13034
156. K. Gundermann, and C. Büchel The fluorescence yield of the trimeric fucoxanthin-chlorophyll-protein FCPa in the diatom Cyclotella meneghiniana is dependent on the amount of bound diatoxanthin Photosynth Res 95 2008 229 235
157. E. Hofmann, P.M. Wrench, F.P. Sharples, R.G. Hiller, W. Welte, and K. Diederichs Structural basis of light harvesting by carotenoids: peridinin-chlorophyll-protein from Amphidinium carterae Science 272 1996 1788 1791
158. T. Schulte, S. Johanning, and E. Hofmann Structure and function of native and refolded peridinin-chlorophyll-proteins from dinoflagellates Eur J Cell Biol 89 2010 990 997
159. Y. Kakitani, R. Fujii, Y. Koyama, H. Nagae, L. Walker, and B. Salter Triplet-state conformational changes in 15-cis-spheroidene bound to the reaction center from Rhodobacter sphaeroides 2.4.1 as revealed by time-resolved EPR spectroscopy: strengthened hypothetical mechanism of triplet-energy dissipation Biochemistry (Mosc) 45 2006 2053 2062
160. J. Martiskainen, R. Kananavicius, J. Linnanto, H. Lehtivuori, M. Keranen, and V. Aumanen Excitation energy transfer in the LHC-II trimer: from carotenoids to chlorophylls in space and time Photosynth Res 107 2011 195 207
161. T. Polivka, and H.A. Frank Molecular factors controlling photosynthetic light harvesting by carotenoids Acc Chem Res 43 2010 1125 1134
162. Y. Koyama, M. Kuki, P.O. Andersson, and T. Gillbro Singlet excited states and the light-harvesting function of carotenoids in bacterial photosynthesis Photochem Photobiol 63 1996 243 256
163. A. Marin, F. Passarini, I.H.M. van Stokkum, R. van Grondelle, and R. Croce Minor complexes at work: light-harvesting by carotenoids in the photosystem II antenna complexes CP24 and CP26 Biophys J 100 2011 2829 2838
164. H.A. Frank, and G.W. Brudvig Redox functions of carotenoids in photosynthesis Biochemistry (Mosc) 43 2004 8607 8615
165. K. Asada Production and scavenging of reactive oxygen species in chloroplasts and their functions Plant Physiol 141 2006 391 396
166. R. Edge, and T.G. Truscott Carotenoid radicals and the interaction of carotenoids with active oxygen species H.A. Frank, A.J. Young, G. Britton, R.J. Cogdell, The photochemistry of carotenoids 1999 Kluwer Academic Publishers Dordrecht, The Netherlands 223 234
167. H.A. Frank, and R.J. Cogdell Carotenoids in photosynthesis Photochem Photobiol 63 1996 257 264
168. H.A. Frank, J.A. Bautista, J.S. Josue, and A.J. Young Mechanism of nonphotochemical quenching in green plants: energies of the lowest excited singlet states of violaxanthin and zeaxanthin Biochemistry (Mosc) 39 2000 2831 2837
169. K.K. Niyogi Safety valves for photosynthesis Curr Opin Plant Biol 3 2000 455 460
170. G. Britton Structure and properties of carotenoids in relation to function FASEB J 9 1995 1551 1558
171. M.G.I. Galinato, D. Niedzwiedzki, C. Deal, R.R. Birge, and H.A. Frank Cation radicals of xanthophylls Photosynth Res 94 2007 67 78
172. I. Baroli, and K.K. Niyogi Molecular genetics of xanthophyll-dependent photoprotection in green algae and plants Philos Trans R Soc Lond B Biol Sci 355 2000 1385 1393
173. R. Berera, C. Herrero, I.H.M. van Stokkum, M. Vengris, G. Kodis, and R.E. Palacios A simple artificial light-harvesting dyad as a model for excess energy dissipation in oxygenic photosynthesis Proc Natl Acad Sci USA 103 2006 5343 5348
174. P. Di Mascio, S. Kaiser, and H. Sies Lycopene as the most efficient biological carotenoid singlet oxygen quencher Arch Biochem Biophys 274 1989 532 538
175. A.A. Woodall, G. Britton, and M.J. Jackson Carotenoids and protection of phospholipids in solution or in liposomes against oxidation by peroxyl radicals: relationship between carotenoid structure and protective ability Biochim Biophys Acta Gen 1336 1997 575 586
176. A.A. Woodall, S.W.M. Lee, R.J. Weesie, M.J. Jackson, and G. Britton Oxidation of carotenoids by free radicals: relationship between structure and reactivity Biochim Biophys Acta Gen 1336 1997 33 42
177. Y. Zhu, J.E. Graham, M. Ludwig, W. Xiong, R.M. Alvey, and G. Shen Roles of xanthophyll carotenoids in protection against photoinhibition and oxidative stress in the cyanobacterium Synechococcus sp. strain PCC 7002 Arch Biochem Biophys 504 2010 86 99
178. T. Götz, U. Windhövel, P. Böger, and G. Sandmann Protection of photosynthesis against ultraviolet-B radiation by carotenoids in transformants of the cyanobacterium Synechococcus PCC7942 Plant Physiol 120 1999 599 604
179. O. Kilian, A.S. Steunou, F. Fazeli, S. Bailey, D. Bhaya, and A.R. Grossman Responses of a thermophilic Synechococcus isolate from the microbial mat of octopus spring to light Appl Environ Microbiol 73 2007 4268 4278
180. N.V. Karapetyan Protective dissipation of excess absorbed energy by photosynthetic apparatus of cyanobacteria: role of antenna terminal emitters Photosynth Res 97 2008 195 204
181. A.G. Ivanov, M. Krol, E. Selstam, P.V. Sane, D. Sveshnikov, and Y.I. Park The induction of CP43′ by iron-stress in Synechococcus sp. PCC 7942 is associated with carotenoid accumulation and enhanced fatty acid unsaturation Biochim Biophys Acta 1767 2007 807 813
182. R.L. Burnap, T. Troyan, and L.A. Sherman The highly abundant chlorophyll-protein complex of iron-deficient Synechococcus sp. PCC7942 (CP43′) is encoded by the isiA gene Plant Physiol 103 1993 893 902
183. M. Havaux, G. Guedeney, M. Hagemann, N. Yeremenko, H.C.P. Matthijs, and R. Jeanjean The chlorophyll-binding protein IsiA is inducible by high light and protects the cyanobacterium Synechocystis PCC6803 from photooxidative stress FEBS Lett 579 2005 2289 2293
184. R. Jeanjean, E. Zuther, N. Yeremenko, M. Havaux, H.C.P. Matthijs, and M. Hagemann A photosystem I psaFJ-null mutant of the cyanobacterium Synechocystis PCC 6803 expresses the isiAB operon under iron replete conditions FEBS Lett 549 2003 52 56
185. D.E. Laudenbach, and N.A. Straus Characterization of a cyanobacterial iron stress-induced gene similar to psbC J Bacteriol 170 1988 5018 5026
186. A. Wilson, C. Boulay, A. Wilde, C.A. Kerfeld, and D. Kirilovsky Light-induced energy dissipation in iron-starved cyanobacteria: roles of OCP and IsiA proteins Plant Cell 19 2007 656 672
187. N. Yousef, E.K. Pistorius, and K.P. Michel Comparative analysis of idiA and isiA transcription under iron starvation and oxidative stress in Synechococcus elongatus PCC 7942 wild-type and selected mutants Arch Microbiol 180 2003 471 483
188. N. Yeremenko, R. Kouril, J.A. Ihalainen, S. D'Haene, N. van Oosterwijk, and E.G. Andrizhiyevskaya Supramolecular organization and dual function of the IsiA chlorophyll-binding protein in cyanobacteria Biochemistry (Mosc) 43 2004 10308 10313
189. J.A. Ihalainen, S. D'Haene, N. Yeremenko, H. van Roon, A.A. Arteni, and E.J. Boekema Aggregates of the chlorophyll-binding protein IsiA (CP43′) dissipate energy in cyanobacteria Biochemistry (Mosc) 44 2005 10846 10853
190. R. Berera, G.F. Moore, I.H.M. van Stokkum, G. Kodis, P.A. Liddell, and M. Gervaldo Charge separation and energy transfer in a caroteno-C-60 dyad: photoinduced electron transfer from the carotenoid excited states Photochem Photobiol Sci 5 2006 1142 1149
191. R. Berera, I.H.M. van Stokkum, S. D'Haene, J.T.M. Kennis, R. van Grondelle, and J.P. Dekker A mechanism of energy dissipation in cyanobacteria Biophys J 96 2009 2261 2267
192. D. Kirilovsky, and C.A. Kerfeld The orange carotenoid protein in photoprotection of photosystem II in cyanobacteria Biochim Biophys Acta Bioenerg 1817 2012 158 166
193. E. Hideg, and U. Schreiber Parallel assessment of ROS formation and photosynthesis in leaves by fluorescence imaging Photosynth Res 92 2007 103 108
194. K.K. Niyogi, A.R. Grossman, and O. Björkman Arabidopsis mutants define a central role for the xanthophyll cycle in the regulation of photosynthetic energy conversion Plant Cell 10 1998 1121 1134
195. 2 evolution in leaves of higher plants Planta 171 1987 171 184
196. P. Jahns, and A.R. Holzwarth The role of the xanthophyll cycle and of lutein in photoprotection of photosystem II Biochim Biophys Acta Bioenerg 1817 2012 182 193
197. M. Havaux, L. Dall'Osto, and R. Bassi Zeaxanthin has enhanced antioxidant capacity with respect to all other xanthophylls in Arabidopsis leaves and functions independent of binding to PSII antennae (1[C][W]) Plant Physiol 145 2007 1506 1520
198. Fufezan C, Simionato D, Morosinotto T. Identification of key residues for pH dependent activation of violaxanthin de-epoxidase from Arabidopsis thaliana. Available from ; 2012.
199. W.W. Adams, B. Demmig-Adams, T.N. Rosenstiel, A.K. Brightwell, and V. Ebbert Photosynthesis and photoprotection in overwintering plants Plant Biol 4 2002 545 557
200. P. Jahns The xanthophyll cycle in intermittent light grown pea plants - possible functions of chlorophyll a/b binding proteins Plant Physiol 108 1995 149 156
201. P. Jahns, A. Wehner, H. Paulsen, and S. Hobe De-epoxidation of violaxanthin after reconstitution into different carotenoid binding sites of light-harvesting complex II J Biol Chem 276 2001 22154 22159
202. G. Oquist, and N.P.A. Huner Photosynthesis of overwintering evergreen plants Ann Rev Plant Biol 54 2003 329 355
203. C. Reinhold, S. Niczyporuk, K.C. Beran, and P. Jahns Short-term down-regulation of zeaxanthin epoxidation in Arabidopsis thaliana in response to photo-oxidative stress conditions Biochim Biophys Acta Bioenerg 1777 2008 462 469
204. A. Wehner, S. Storf, P. Jahns, and V.H.R. Schmid De-epoxidation of violaxanthin in light-harvesting complex I proteins J Biol Chem 279 2004 26823 26829
205. A. Wehner, T. Grasses, and P. Jahns De-epoxidation of violaxanthin in the minor antenna proteins of photosystem II, LHCB4, LHCB5, and LHCB6 J Biol Chem 281 2006 21924 21933
206. A.R. Holzwarth, Y. Miloslavina, M. Nilkens, and P. Jahns Identification of two quenching sites active in the regulation of photosynthetic light-harvesting studied by time-resolved fluorescence Chem Phys Lett 483 2009 262 267
207. N.E. Holt, D. Zigmantas, L. Valkunas, X.P. Li, K.K. Niyogi, and G.R. Fleming Carotenoid cation formation and the regulation of photosynthetic light harvesting Science 307 2005 433 436
208. A.V. Ruban, M.P. Johnson, and C.D. Duffy The photoprotective molecular switch in the photosystem II antenna Biochim Biophys Acta 1817 2012 167 181
209. R. Bassi, and P. Dainese A supramolecular light-harvesting complex from chloroplast photosystem-II membranes Eur J Biochem 204 1992 317 326
210. R. Bassi, B. Pineau, P. Dainese, and J. Marquardt Carotenoid-binding proteins of photosystem II Eur J Biochem 212 1993 297 303
211. P.J.G. Butler, and W. Kühlbrandt Determination of the aggregate size in detergent solution of the light-harvesting chlorophyll a/b-protein complex from chloroplast membranes Proc Natl Acad Sci USA 85 1988 3797 3801
212. A.V. Ruban, A.J. Young, A.A. Pascal, and P. Horton The effects of illumination on the xanthophyll composition of the photosystem II light-harvesting complexes of spinach thylakoid membranes Plant Physiol 104 1994 227 234
213. A.V. Ruban, R. Berera, C. Ilioaia, I.H.M. van Stokkum, J.T.M. Kennis, and A.A. Pascal Identification of a mechanism of photoprotective energy dissipation in higher plants Nature 450 2007 575 578
214. T.P. Krüger, C. Ilioaia, M.P. Johnson, A.V. Ruban, E. Papagiannakis, and P. Horton Controlled disorder in plant light-harvesting complex II explains its photoprotective role Biophys J 102 2012 2669 2676
215. T.K. Ahn, T.J. Avenson, M. Ballottari, Y.C. Cheng, K.K. Niyogi, and R. Bassi Architecture of a charge-transfer state regulating light harvesting in a plant antenna protein Science 320 2008 794 797
216. L. Kalituho, J. Rech, and P. Jahns The roles of specific xanthophylls in light utilization Planta 225 2007 423 439
217. K.K. Niyogi, C. Shih, W.S. Chow, B.J. Pogson, D. DellaPenna, and O. Björkman Photoprotection in a zeaxanthin- and lutein-deficient double mutant of Arabidopsis Photosynth Res 67 2001 139 145
218. L. Dall'Osto, A. Fiore, S. Cazzaniga, G. Giuliano, and R. Bassi Different roles of α- and β-branch xanthophylls in photosystem assembly and photoprotection J Biol Chem 282 2007 35056 35068
219. S. de Bianchi, M. Ballottari, L. Dall'Osto, and R. Bassi Regulation of plant light harvesting by thermal dissipation of excess energy Biochem Soc Trans 38 2010 651 660
220. Z.R. Li, T.K. Ahn, T.J. Avenson, M. Ballottari, J.A. Cruz, and D.M. Kramer Lutein accumulation in the absence of zeaxanthin restores nonphotochemical quenching in the Arabidopsis thaliana npq1 mutant Plant Cell 21 2009 1798 1812
221. M. Nilkens, E. Kress, P. Lambrev, Y. Miloslavina, M. Muller, and A.R. Holzwarth Identification of a slowly inducible zeaxanthin-dependent component of non-photochemical quenching of chlorophyll fluorescence generated under steady-state conditions in Arabidopsis Biochim Biophys Acta Bioenerg 1797 2010 466 475
222. F. Ramel, S. Birtic, S. Cuine, C. Triantaphylides, J.L. Ravanat, and M. Havaux Chemical quenching of singlet oxygen by carotenoids in plants Plant Physiol 158 2012 1267 1278
223. A. Telfer What is β-carotene doing in the photosystem II reaction centre? Philos Trans R Soc Lond B Biol Sci 357 2002 1431 1439
224. C.A. Tracewell, J.S. Vrettos, J.A. Bautista, H.A. Frank, and G.W. Brudvig Carotenoid photooxidation in photosystem II Arch Biochem Biophys 385 2001 61 69
225. M. Zubik, R. Luchowski, W. Grudzinski, M. Gospodarek, I. Gryczynski, and Z. Gryczynski Light-induced isomerization of the LHCII-bound xanthophyll neoxanthin: possible implications for photoprotection in plants Biochim Biophys Acta Bioenerg 1807 2011 1237 1243
226. L. Dall'Osto, S. Cazzaniga, H. North, A. Marion-Poll, and R. Bassi The Arabidopsis aba4-1 mutant reveals a specific function for neoxanthin in protection against photooxidative stress Plant Cell 19 2007 1048 1064
227. M. Di Valentin, S. Ceola, E. Salvadori, G. Agostini, and D. Carbonera Identification by time-resolved EPR of the peridinins directly involved in chlorophyll triplet quenching in the peridinin-chlorophyll a-protein from Amphidinium carterae Biochim Biophys Acta Bioenerg 1777 2008 186 195
228. M. Di Valentin, G. Agostini, E. Salvadori, S. Ceola, G.M. Giacometti, and R.G. Hiller Triplet-triplet energy transfer in peridinin-chlorophyll a-protein reconstituted with Chl a and Chl d as revealed by optically detected magnetic resonance and pulse EPR: comparison with the native PCP complex from Amphidinium carterae Biochim Biophys Acta Bioenerg 1787 2009 168 175
229. J.M. Cock, L. Sterck, P. Rouzé, D. Scornet, A.E. Allen, and G. Amoutzias The Ectocarpus genome and the independent evolution of multicellularity in brown algae Nature 465 2010 617 621
230. M. Di Valentin, C. Büchel, G.M. Giacometti, and D. Carbonera Chlorophyll triplet quenching by fucoxanthin in the fucoxanthin-chlorophyll protein from the diatom Cyclotella meneghiniana Biochem Biophys Res Commun 427 2012 637 641
231. E. Kotabova, R. Kana, J. Jaresova, and O. Prasil Non-photochemical fluorescence quenching in Chromera velia is enabled by fast violaxanthin de-epoxidation FEBS Lett 585 2011 1941 1945
232. D. Elrad, K.K. Niyogi, and A.R. Grossman A major light-harvesting polypeptide of photosystem II functions in thermal dissipation Plant Cell 14 2002 1801 1816
233. P. Ferrante, M. Ballottari, G. Bonente, G. Giuliano, and R. Bassi LHCBM1 and LHCBM2/7 polypeptides, components of major LHCII complex, have distinct functional roles in photosynthetic antenna system of Chlamydomonas reinhardtii J Biol Chem 287 2012 16276 16288
234. K.K. Niyogi, O. Björkman, and A.R. Grossman The roles of specific xanthophylls in photoprotection Proc Natl Acad Sci USA 94 1997 14162 14167
235. Bonente G, Ballottari M, Truong TB, Morosinotto T, Ahn TK, Fleming GR et al. Analysis of LhcSR3, a protein essential for feedback de-excitation in the green alga Chlamydomonas reinhardtii. Available from ; 2011:e1000577.
236. R. Miller, G. Wu, R.R. Deshpande, A. Vieler, K. Gartner, and X. Li Changes in transcript abundance in Chlamydomonas reinhardtii following nitrogen deprivation predict diversion of metabolism Plant Physiol 154 2010 1737 1752
237. T.K. Holt, and D.W. Krogmann A carotenoid protein from cyanobacteria Biochim Biophys Acta 637 1981 408 414
238. G.S. Bullerjahn, and L.A. Sherman Identification of a carotenoid-binding protein in the cytoplasmic membrane from the heterotrophic cyanobacterium Synechocystis sp. strain PCC6714 J Bacteriol 167 1986 396 399
239. U.J. Jurgens, and J. Weckesser Carotenoid-containing outer membrane of Synechocystis sp. strain PCC6714 J Bacteriol 164 1985 384 389
240. K. Masamoto, H.C. Riethman, and L.A. Sherman Isolation and characterization of a carotenoid-associated thylakoid protein from the cyanobacterium Anacystis nidulans R2 Plant Physiol 84 1987 633 639
241. Y.P. Wu, and D.W. Krogmann The orange carotenoid protein of Synechocystis PCC 6803 Biochim Biophys Acta Bioenerg 1322 1997 1 7
242. C.A. Kerfeld Water-soluble carotenoid proteins of cyanobacteria Arch Biochem Biophys 430 2004 2 9
243. C. Boulay, L. Abasova, C. Six, I. Vass, and D. Kirilovsky Occurrence and function of the orange carotenoid protein in photoprotective mechanisms in various cyanobacteria Biochim Biophys Acta Bioenerg 1777 2008 1344 1354
244. C.A. Kerfeld Structure and function of the water-soluble carotenoid-binding proteins of cyanobacteria Photosynth Res 81 2004 215 225
245. K.J. Reddy, K. Masamoto, D.M. Sherman, and L.A. Sherman DNA sequence and regulation of the gene (cbpA) encoding the 42-kilodalton cytoplasmic membrane carotenoprotein of the cyanobacterium Synechococcus sp. strain PCC7942 J Bacteriol 171 1989 3486 3493
246. U.J. Jurgens, and W. Mantele Orientation of carotenoids in the outer-membrane of Synechocystis PCC6714 (Cyanobacteria) Biochim Biophys Acta 1067 1991 208 212
247. C.A. Kerfeld, M.R. Sawaya, V. Brahmandam, D. Cascio, K.K. Ho, and C.C. Trevithick-Sutton The crystal structure of a cyanobacterial water-soluble carotenoid binding protein Structure 11 2003 55 65
248. T.L. Bullock, W.D. Clarkson, H.M. Kent, and M. Stewart The 1.6 Å resolution crystal structure of nuclear transport factor 2 (NTF2) J Mol Biol 260 1996 422 431
249. K. El Bissati, E. Delphin, N. Murata, A.L. Etienne, and D. Kirilovsky Photosystem II fluorescence quenching in the cyanobacterium Synechocystis PCC 6803: involvement of two different mechanisms Biochim Biophys Acta Bioenerg 1457 2000 229 242
250. A. Wilson, G. Ajlani, J.M. Verbavatz, I. Vass, C.A. Kerfeld, and D. Kirilovsky A soluble carotenoid protein involved in phycobilisome-related energy dissipation in cyanobacteria Plant Cell 18 2006 992 1007
251. A. Wilson, J.N. Kinney, P.H. Zwart, C. Punginelli, S. D'Haene, and F. Perreau Structural determinants underlying photoprotection in the photoactive Orange Carotenoid Protein of cyanobacteria J Biol Chem 285 2010 18364 18375
252. A. Wilson, C. Punginelli, A. Gall, C. Bonetti, M. Alexandre, and J.M. Routaboul A photoactive carotenoid protein acting as light intensity sensor Proc Natl Acad Sci USA 105 2008 12075 12080
253. M. Diverse-Pierluissi, and D.W. Krogmann A zeaxanthin protein from Anacystis nidulans Biochim Biophys Acta 933 1988 372 377
254. C. Punginelli, A. Wilson, J.M. Routaboul, and D. Kirilovsky Influence of zeaxanthin and echinenone binding on the activity of the Orange Carotenoid Protein Biochim Biophys Acta Bioenerg 1787 2009 280 288
255. A. Wilson, M. Gwizdala, A. Mezzetti, M. Alexandre, C.A. Kerfeld, and D. Kirilovsky The essential role of the N-terminal domain of the Orange Carotenoid Protein in cyanobacterial photoprotection: importance of a positive charge for phycobilisome binding Plant Cell 24 2012 1972 1983
256. M. Gwizdala, A. Wilson, and D. Kirilovsky In vitro reconstitution of the cyanobacterial photoprotective mechanism mediated by the Orange Carotenoid Protein in Synechocystis PCC 6803 Plant Cell 23 2011 2631 2643
257. D. Jallet, M. Gwizdala, and D. Kirilovsky ApcD, ApcF and ApcE are not required for the Orange Carotenoid Protein related phycobilisome fluorescence quenching in the cyanobacterium Synechocystis PCC 6803 Biochim Biophys Acta Bioenerg 1817 2012 1418 1427
258. L.J. Tian, I.H.M. van Stokkum, R.B.M. Koehorst, A. Jongerius, D. Kirilovsky, and H. van Amerongen Site, rate, and mechanism of photoprotective quenching in cyanobacteria J Am Chem Soc 133 2011 18304 18311
259. L.J. Tian, M. Gwizdala, I.H.M. van Stokkum, R.B.M. Koehorst, D. Kirilovsky, and H. van Amerongen Picosecond kinetics of light harvesting and photoprotective quenching in wild-type and mutant phycobilisomes isolated from the cyanobacterium Synechocystis PCC 6803 Biophys J 102 2012 1692 1700
260. C. Boulay, A. Wilson, S. D'Haene, and D. Kirilovsky Identification of a protein required for recovery of full antenna capacity in OCP-related photoprotective mechanism in cyanobacteria Proc Natl Acad Sci USA 107 2010 11620 11625
261. T. Nagano, K. Kojima, T. Hisabori, H. Hayashi, E.H. Morita, and T. Kanamori Elongation factor G is a critical target during oxidative damage to the translation system of Escherichia coli J Biol Chem 287 2012 28697 28704
262. K. Kojima, M. Oshita, Y. Nanjo, K. Kasai, Y. Tozawa, and H. Hayashi Oxidation of elongation factor G inhibits the synthesis of the D1 protein of photosystem II Mol Microbiol 65 2007 936 947
263. K. Ejima, T. Kawaharada, S. Inoue, K. Kojima, and Y. Nishiyama A change in the sensitivity of elongation factor G to oxidation protects photosystem II from photoinhibition in Synechocystis sp. PCC 6803 FEBS Lett 586 2012 778 783
264. L. Dall'Osto, M. Piques, M. Ronzani, B. Molesini, A. Alboresi, and S. Cazzaniga The Arabidopsis nox mutant lacking carotene hydroxylase activity reveals a critical role for xanthophylls in Photosystem I biogenesis Plant Cell 25 2013 591 608