-
1
-
-
34247208187
-
Advanced Parkinson disease treated with rotigotine transdermal system: PREFER Study
-
LeWitt P.A., Lyons K.E., Pahwa R. Advanced Parkinson disease treated with rotigotine transdermal system: PREFER Study. Neurology 2007, 68(16):1262-1267.
-
(2007)
Neurology
, vol.68
, Issue.16
, pp. 1262-1267
-
-
LeWitt, P.A.1
Lyons, K.E.2
Pahwa, R.3
-
2
-
-
72149094883
-
Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders
-
Voon V., Fernagut P.O., Wickens J., et al. Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders. Lancet Neurol 2009, 8(12):1140-1149.
-
(2009)
Lancet Neurol
, vol.8
, Issue.12
, pp. 1140-1149
-
-
Voon, V.1
Fernagut, P.O.2
Wickens, J.3
-
3
-
-
57349093766
-
Levodopa for the treatment of Parkinson's disease
-
LeWitt P.A. Levodopa for the treatment of Parkinson's disease. NEngl J Med 2008, 359(23):2468-2476.
-
(2008)
NEngl J Med
, vol.359
, Issue.23
, pp. 2468-2476
-
-
LeWitt, P.A.1
-
4
-
-
79952051533
-
Levodopa in the treatment of Parkinson's disease: an old drug still going strong
-
Poewe W., Antonini A., Zijlmans J.C., et al. Levodopa in the treatment of Parkinson's disease: an old drug still going strong. Clin Interv Aging 2010, 5:229-238.
-
(2010)
Clin Interv Aging
, vol.5
, pp. 229-238
-
-
Poewe, W.1
Antonini, A.2
Zijlmans, J.C.3
-
5
-
-
0027988507
-
Problems with long-term levodopa therapy for Parkinson's disease
-
Marsden C.D. Problems with long-term levodopa therapy for Parkinson's disease. Clin Neuropharmacol 1994, 17(Suppl 2):S32-S44.
-
(1994)
Clin Neuropharmacol
, vol.17
, Issue.SUPPL. 2
-
-
Marsden, C.D.1
-
6
-
-
77949565053
-
When do levodopa motor fluctuations first appear in Parkinson's disease?
-
Stocchi F., Jenner P., Obeso J.A. When do levodopa motor fluctuations first appear in Parkinson's disease?. Eur Neurol 2010, 63(5):257-266.
-
(2010)
Eur Neurol
, vol.63
, Issue.5
, pp. 257-266
-
-
Stocchi, F.1
Jenner, P.2
Obeso, J.A.3
-
7
-
-
14944364987
-
Impact of the motor complications of Parkinson's disease on the quality of life
-
Chapuis S., Ouchchane L., Metz O., et al. Impact of the motor complications of Parkinson's disease on the quality of life. Mov Disord 2005, 20(2):224-230.
-
(2005)
Mov Disord
, vol.20
, Issue.2
, pp. 224-230
-
-
Chapuis, S.1
Ouchchane, L.2
Metz, O.3
-
8
-
-
29244453213
-
Effects of dyskinesias in Parkinson's disease on quality of life and health-related costs: a prospective European study
-
Pechevis M., Clarke C.E., Vieregge P., et al. Effects of dyskinesias in Parkinson's disease on quality of life and health-related costs: a prospective European study. Eur J Neurol 2005, 12(12):956-963.
-
(2005)
Eur J Neurol
, vol.12
, Issue.12
, pp. 956-963
-
-
Pechevis, M.1
Clarke, C.E.2
Vieregge, P.3
-
9
-
-
77957966489
-
Levodopa-induced dyskinesias inpatients with Parkinson's disease: filling the bench-to-bedside gap
-
Calabresi P., Di Filippo M., Ghiglieri V., et al. Levodopa-induced dyskinesias inpatients with Parkinson's disease: filling the bench-to-bedside gap. Lancet Neurol 2010, 9(11):1106-1117.
-
(2010)
Lancet Neurol
, vol.9
, Issue.11
, pp. 1106-1117
-
-
Calabresi, P.1
Di Filippo, M.2
Ghiglieri, V.3
-
10
-
-
50049087567
-
Molecular mechanisms of L-DOPA-induced dyskinesia
-
Jenner P. Molecular mechanisms of L-DOPA-induced dyskinesia. Nat Rev Neurosci 2008, 9(9):665-677.
-
(2008)
Nat Rev Neurosci
, vol.9
, Issue.9
, pp. 665-677
-
-
Jenner, P.1
-
11
-
-
34948819210
-
The Yin and Yang of dopamine release: a new perspective
-
Goto Y., Otani S., Grace A.A. The Yin and Yang of dopamine release: a new perspective. Neuropharmacology 2007, 53(5):583-587.
-
(2007)
Neuropharmacology
, vol.53
, Issue.5
, pp. 583-587
-
-
Goto, Y.1
Otani, S.2
Grace, A.A.3
-
12
-
-
0026457051
-
Continuous lisuride effects on central dopaminergic mechanisms in Parkinson's disease
-
Baronti F., Mouradian M.M., Davis T.L., et al. Continuous lisuride effects on central dopaminergic mechanisms in Parkinson's disease. Ann Neurol 1992, 32(6):776-781.
-
(1992)
Ann Neurol
, vol.32
, Issue.6
, pp. 776-781
-
-
Baronti, F.1
Mouradian, M.M.2
Davis, T.L.3
-
13
-
-
13444273340
-
Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates
-
Bibbiani F., Costantini L.C., Patel R., et al. Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates. Exp Neurol 2005, 192(1):73-78.
-
(2005)
Exp Neurol
, vol.192
, Issue.1
, pp. 73-78
-
-
Bibbiani, F.1
Costantini, L.C.2
Patel, R.3
-
14
-
-
0028835737
-
Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U-91356A) in MPTP-exposed monkeys
-
Blanchet P.J., Calon F., Martel J.C., et al. Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U-91356A) in MPTP-exposed monkeys. JPharmacol Exp Ther 1995, 272(2):854-859.
-
(1995)
JPharmacol Exp Ther
, vol.272
, Issue.2
, pp. 854-859
-
-
Blanchet, P.J.1
Calon, F.2
Martel, J.C.3
-
15
-
-
0024436486
-
Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists
-
Engber T.M., Susel Z., Juncos J.L., et al. Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists. EurJPharmacol 1989, 168(3):291-298.
-
(1989)
EurJPharmacol
, vol.168
, Issue.3
, pp. 291-298
-
-
Engber, T.M.1
Susel, Z.2
Juncos, J.L.3
-
16
-
-
22544451262
-
Apromising new technology for Parkinson's disease
-
Pfeiffer R.F. Apromising new technology for Parkinson's disease. Neurology 2005, 65(2 Suppl 1):S6-S10.
-
(2005)
Neurology
, vol.65
, Issue.2 SUPPL. 1
-
-
Pfeiffer, R.F.1
-
17
-
-
22544444943
-
Anovel dopamine agonist for the transdermal treatment of Parkinson's disease
-
Jenner P. Anovel dopamine agonist for the transdermal treatment of Parkinson's disease. Neurology 2005, 65(2 Suppl 1):S3-S5.
-
(2005)
Neurology
, vol.65
, Issue.2 SUPPL. 1
-
-
Jenner, P.1
-
18
-
-
0022501055
-
Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734
-
Van der Weide J., De Vries J.B., Tepper P.G., et al. Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734. Eur J Pharmacol 1986, 125(2):273-282.
-
(1986)
Eur J Pharmacol
, vol.125
, Issue.2
, pp. 273-282
-
-
Van der Weide, J.1
De Vries, J.B.2
Tepper, P.G.3
-
19
-
-
0023840168
-
The enantiomers of the D-2 dopamine receptor agonist N-0437 discriminate between pre- and postsynaptic dopamine receptors
-
Van der Weide J., Tendijck M.E., Tepper P.G., et al. The enantiomers of the D-2 dopamine receptor agonist N-0437 discriminate between pre- and postsynaptic dopamine receptors. Eur J Pharmacol 1988, 146(2-3):319-326.
-
(1988)
Eur J Pharmacol
, vol.146
, Issue.2-3
, pp. 319-326
-
-
Van der Weide, J.1
Tendijck, M.E.2
Tepper, P.G.3
-
20
-
-
0028324501
-
N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease
-
Belluzzi J.D., Domino E.F., May J.M., et al. N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease. Mov Disord 1994, 9(2):147-154.
-
(1994)
Mov Disord
, vol.9
, Issue.2
, pp. 147-154
-
-
Belluzzi, J.D.1
Domino, E.F.2
May, J.M.3
-
21
-
-
0024410589
-
Stereoselective reversal of MPTP-induced parkinsonism in the marmoset after dermal application of N-0437
-
Loschmann P.A., Chong P.N., Nomoto M., et al. Stereoselective reversal of MPTP-induced parkinsonism in the marmoset after dermal application of N-0437. Eur J Pharmacol 1989, 166(3):373-380.
-
(1989)
Eur J Pharmacol
, vol.166
, Issue.3
, pp. 373-380
-
-
Loschmann, P.A.1
Chong, P.N.2
Nomoto, M.3
-
22
-
-
0026525017
-
Complex prejunctional actions of the D2 dopamine agonists N-0923 and N-0924 in the rat tail artery
-
Friedman D.J., Krause D.N., Duckles S.P. Complex prejunctional actions of the D2 dopamine agonists N-0923 and N-0924 in the rat tail artery. JPharmacol Exp Ther 1992, 260(2):568-575.
-
(1992)
JPharmacol Exp Ther
, vol.260
, Issue.2
, pp. 568-575
-
-
Friedman, D.J.1
Krause, D.N.2
Duckles, S.P.3
-
23
-
-
59449110327
-
The invitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease
-
Scheller D., Ullmer C., Berkels R., et al. The invitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol 2009, 379(1):73-86.
-
(2009)
Naunyn Schmiedebergs Arch Pharmacol
, vol.379
, Issue.1
, pp. 73-86
-
-
Scheller, D.1
Ullmer, C.2
Berkels, R.3
-
24
-
-
0036827811
-
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes
-
Millan M.J., Maiofiss L., Cussac D., et al. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes. JPharmacol Exp Ther 2002, 303(2):791-804.
-
(2002)
JPharmacol Exp Ther
, vol.303
, Issue.2
, pp. 791-804
-
-
Millan, M.J.1
Maiofiss, L.2
Cussac, D.3
-
25
-
-
33645675839
-
Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease
-
Radad K., Gille G., Rausch W.D. Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease. Pharmacol Rep 2005, 57(6):701-712.
-
(2005)
Pharmacol Rep
, vol.57
, Issue.6
, pp. 701-712
-
-
Radad, K.1
Gille, G.2
Rausch, W.D.3
-
26
-
-
1542327580
-
Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease
-
Jenner P. Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease. Curr Opin Neurol 2003, 16(Suppl 1):S3-S7.
-
(2003)
Curr Opin Neurol
, vol.16
, Issue.SUPPL. 1
-
-
Jenner, P.1
-
27
-
-
0034741123
-
Dopamine D3 receptor as a therapeutic target for antipsychotic and antiparkinsonian drugs
-
Joyce J.N. Dopamine D3 receptor as a therapeutic target for antipsychotic and antiparkinsonian drugs. Pharmacol Ther 2001, 90(2-3):231-259.
-
(2001)
Pharmacol Ther
, vol.90
, Issue.2-3
, pp. 231-259
-
-
Joyce, J.N.1
-
28
-
-
0030610305
-
The D3 dopamine receptor: neurobiology and potential clinical relevance
-
Levant B. The D3 dopamine receptor: neurobiology and potential clinical relevance. Pharmacol Rev 1997, 49(3):231-252.
-
(1997)
Pharmacol Rev
, vol.49
, Issue.3
, pp. 231-252
-
-
Levant, B.1
-
29
-
-
6844250767
-
Dopamine receptors: from structure to function
-
Missale C., Nash S.R., Robinson S.W., et al. Dopamine receptors: from structure to function. Physiol Rev 1998, 78(1):189-225.
-
(1998)
Physiol Rev
, vol.78
, Issue.1
, pp. 189-225
-
-
Missale, C.1
Nash, S.R.2
Robinson, S.W.3
-
30
-
-
0026589493
-
Dopamine receptor interactions: some implications for the treatment of Parkinson's disease
-
Robertson H.A. Dopamine receptor interactions: some implications for the treatment of Parkinson's disease. Trends Neurosci 1992, 15(6):201-206.
-
(1992)
Trends Neurosci
, vol.15
, Issue.6
, pp. 201-206
-
-
Robertson, H.A.1
-
31
-
-
0028171261
-
The dopamine D1 agonist SKF 81297 and the dopamine D2 agonist LY 171555 act synergistically to stimulate motor behavior of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned parkinsonian rhesus monkeys
-
Vermeulen R.J., Drukarch B., Sahadat M.C., et al. The dopamine D1 agonist SKF 81297 and the dopamine D2 agonist LY 171555 act synergistically to stimulate motor behavior of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned parkinsonian rhesus monkeys. Mov Disord 1994, 9(6):664-672.
-
(1994)
Mov Disord
, vol.9
, Issue.6
, pp. 664-672
-
-
Vermeulen, R.J.1
Drukarch, B.2
Sahadat, M.C.3
-
32
-
-
77649147161
-
Neurotransmission in Parkinson's disease: beyond dopamine
-
Barone P. Neurotransmission in Parkinson's disease: beyond dopamine. EurJNeurol 2010, 17(3):364-376.
-
(2010)
EurJNeurol
, vol.17
, Issue.3
, pp. 364-376
-
-
Barone, P.1
-
33
-
-
64349083816
-
Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
-
Chaudhuri K.R., Schapira A.H. Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment. Lancet Neurol 2009, 8(5):464-474.
-
(2009)
Lancet Neurol
, vol.8
, Issue.5
, pp. 464-474
-
-
Chaudhuri, K.R.1
Schapira, A.H.2
-
34
-
-
51449123001
-
Non-dopaminergic treatments in development for Parkinson's disease
-
Fox S.H., Brotchie J.M., Lang A.E. Non-dopaminergic treatments in development for Parkinson's disease. Lancet Neurol 2008, 7(10):927-938.
-
(2008)
Lancet Neurol
, vol.7
, Issue.10
, pp. 927-938
-
-
Fox, S.H.1
Brotchie, J.M.2
Lang, A.E.3
-
35
-
-
0028147598
-
Antidepressant-like behavioral effects of serotonin receptor agonists
-
Lucki I., Singh A., Kreiss D.S. Antidepressant-like behavioral effects of serotonin receptor agonists. Neurosci Biobehav Rev 1994, 18(1):85-95.
-
(1994)
Neurosci Biobehav Rev
, vol.18
, Issue.1
, pp. 85-95
-
-
Lucki, I.1
Singh, A.2
Kreiss, D.S.3
-
36
-
-
65049083026
-
5-HT(1A) receptor function in major depressive disorder
-
Savitz J., Lucki I., Drevets W.C. 5-HT(1A) receptor function in major depressive disorder. Prog Neurobiol 2009, 88(1):17-31.
-
(2009)
Prog Neurobiol
, vol.88
, Issue.1
, pp. 17-31
-
-
Savitz, J.1
Lucki, I.2
Drevets, W.C.3
-
37
-
-
0036460744
-
5-Hydroxytryptamine (5-HT, serotonin) and Parkinson's disease - opportunities for novel therapeutics to reduce the problems of levodopa therapy
-
Nicholson S.L., Brotchie J.M. 5-Hydroxytryptamine (5-HT, serotonin) and Parkinson's disease - opportunities for novel therapeutics to reduce the problems of levodopa therapy. Eur J Neurol 2002, 9(Suppl 3):1-6.
-
(2002)
Eur J Neurol
, vol.9
, Issue.SUPPL. 3
, pp. 1-6
-
-
Nicholson, S.L.1
Brotchie, J.M.2
-
38
-
-
78751653077
-
Therapeutic role of 5-HT1A receptors in the treatment of schizophrenia and Parkinson's disease
-
Ohno Y. Therapeutic role of 5-HT1A receptors in the treatment of schizophrenia and Parkinson's disease. CNS Neurosci Ther 2011, 17(1):58-65.
-
(2011)
CNS Neurosci Ther
, vol.17
, Issue.1
, pp. 58-65
-
-
Ohno, Y.1
-
39
-
-
0032588996
-
The alpha2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease
-
Henry B., Fox S.H., Peggs D., et al. The alpha2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease. Mov Disord 1999, 14(5):744-753.
-
(1999)
Mov Disord
, vol.14
, Issue.5
, pp. 744-753
-
-
Henry, B.1
Fox, S.H.2
Peggs, D.3
-
40
-
-
33645030240
-
Changes of sleep architecture, spectral composition of sleep EEG, the nocturnal secretion of cortisol, ACTH, GH, prolactin, melatonin, ghrelin, and leptin, and the DEX-CRH test in depressed patients during treatment with mirtazapine
-
Schmid D.A., Wichniak A., Uhr M., et al. Changes of sleep architecture, spectral composition of sleep EEG, the nocturnal secretion of cortisol, ACTH, GH, prolactin, melatonin, ghrelin, and leptin, and the DEX-CRH test in depressed patients during treatment with mirtazapine. Neuropsychopharmacology 2006, 31(4):832-844.
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.4
, pp. 832-844
-
-
Schmid, D.A.1
Wichniak, A.2
Uhr, M.3
-
41
-
-
34547102981
-
Continuous delivery of rotigotine decreases extracellular dopamine suggesting continuous receptor stimulation
-
Kehr J., Hu X.J., Goiny M., et al. Continuous delivery of rotigotine decreases extracellular dopamine suggesting continuous receptor stimulation. JNeural Transm 2007, 114(8):1027-1031.
-
(2007)
JNeural Transm
, vol.114
, Issue.8
, pp. 1027-1031
-
-
Kehr, J.1
Hu, X.J.2
Goiny, M.3
-
42
-
-
52449089646
-
Continuous versus pulsatile administration of rotigotine in 6-OHDA-lesioned rats: contralateral rotations and abnormal involuntary movements
-
Schmidt W.J., Lebsanft H., Heindl M., et al. Continuous versus pulsatile administration of rotigotine in 6-OHDA-lesioned rats: contralateral rotations and abnormal involuntary movements. JNeural Transm 2008, 115(10):1385-1392.
-
(2008)
JNeural Transm
, vol.115
, Issue.10
, pp. 1385-1392
-
-
Schmidt, W.J.1
Lebsanft, H.2
Heindl, M.3
-
43
-
-
69949101386
-
Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction
-
Stockwell K.A., Scheller D., Rose S., et al. Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction. Exp Neurol 2009, 219(2):533-542.
-
(2009)
Exp Neurol
, vol.219
, Issue.2
, pp. 533-542
-
-
Stockwell, K.A.1
Scheller, D.2
Rose, S.3
-
44
-
-
84881531516
-
-
European Medicines Agency. Neupro: EPAR Product information. Available at:. Accessed May 15
-
European Medicines Agency. Neupro: EPAR Product information. Available at:. Accessed May 15, 2013. http://www.emea.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000626/human_med_000926.jsp&mid=WC0b01ac058001d124.
-
(2013)
-
-
-
45
-
-
84881484500
-
-
European Medicines Agency. Neupro: EPAR Scientific discussion. Available at: Accessed October 25
-
European Medicines Agency. Neupro: EPAR Scientific discussion. Available at: Accessed October 25, 2012. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Scientific_Discussion/human/000626/WC500026394.pdf.
-
(2012)
-
-
-
46
-
-
84861199463
-
Long-term safety and tolerability of rotigotine transdermal system in patients with early-stage idiopathic Parkinson's disease: a prospective, open-label extension study
-
Elmer L.W., Surmann E., Boroojerdi B., et al. Long-term safety and tolerability of rotigotine transdermal system in patients with early-stage idiopathic Parkinson's disease: a prospective, open-label extension study. Parkinsonism Relat Disord 2012, 18(5):488-493.
-
(2012)
Parkinsonism Relat Disord
, vol.18
, Issue.5
, pp. 488-493
-
-
Elmer, L.W.1
Surmann, E.2
Boroojerdi, B.3
-
47
-
-
34249033784
-
Transdermal rotigotine: double-blind, placebo-controlled trial in Parkinson disease
-
Jankovic J., Watts R.L., Martin W., et al. Transdermal rotigotine: double-blind, placebo-controlled trial in Parkinson disease. Arch Neurol 2007, 64(5):676-682.
-
(2007)
Arch Neurol
, vol.64
, Issue.5
, pp. 676-682
-
-
Jankovic, J.1
Watts, R.L.2
Martin, W.3
-
48
-
-
0346754905
-
Acontrolled trial of rotigotine monotherapy in early Parkinson's disease
-
Parkinson Study Group
-
Parkinson Study Group Acontrolled trial of rotigotine monotherapy in early Parkinson's disease. Arch Neurol 2003, 60(12):1721-1728.
-
(2003)
Arch Neurol
, vol.60
, Issue.12
, pp. 1721-1728
-
-
-
49
-
-
79951477585
-
Rotigotine effects on early morning motor function and sleep in Parkinson's disease: a double-blind, randomized, placebo-controlled study (RECOVER)
-
Trenkwalder C., Kies B., Rudzinska M., et al. Rotigotine effects on early morning motor function and sleep in Parkinson's disease: a double-blind, randomized, placebo-controlled study (RECOVER). Mov Disord 2011, 26(1):90-99.
-
(2011)
Mov Disord
, vol.26
, Issue.1
, pp. 90-99
-
-
Trenkwalder, C.1
Kies, B.2
Rudzinska, M.3
-
50
-
-
33846438955
-
Randomized, blind, controlled trial of transdermal rotigotine in early Parkinson disease
-
Watts R.L., Jankovic J., Waters C., et al. Randomized, blind, controlled trial of transdermal rotigotine in early Parkinson disease. Neurology 2007, 68(4):272-276.
-
(2007)
Neurology
, vol.68
, Issue.4
, pp. 272-276
-
-
Watts, R.L.1
Jankovic, J.2
Waters, C.3
-
51
-
-
0026460063
-
Extensive gastrointestinal metabolic conversion limits the oral bioavailability of the dopamine D2 agonist N-0923 in freely moving rats
-
Swart P.J., De Zeeuw R.A. Extensive gastrointestinal metabolic conversion limits the oral bioavailability of the dopamine D2 agonist N-0923 in freely moving rats. Pharmazie 1992, 47(8):613-615.
-
(1992)
Pharmazie
, vol.47
, Issue.8
, pp. 613-615
-
-
Swart, P.J.1
De Zeeuw, R.A.2
-
52
-
-
0027215269
-
Pharmacokinetics of the dopamine D2 agonist S(-)-2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in freely moving rats
-
Swart P.J., de Zeeuw R.A. Pharmacokinetics of the dopamine D2 agonist S(-)-2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in freely moving rats. JPharm Sci 1993, 82(2):200-203.
-
(1993)
JPharm Sci
, vol.82
, Issue.2
, pp. 200-203
-
-
Swart, P.J.1
de Zeeuw, R.A.2
-
53
-
-
0031656485
-
N-0923, a novel soluble dopamine D2 agonist in the treatment of parkinsonism
-
Calabrese V.P., Lloyd K.A., Brancazio P., et al. N-0923, a novel soluble dopamine D2 agonist in the treatment of parkinsonism. Mov Disord 1998, 13(5):768-774.
-
(1998)
Mov Disord
, vol.13
, Issue.5
, pp. 768-774
-
-
Calabrese, V.P.1
Lloyd, K.A.2
Brancazio, P.3
-
54
-
-
0035353743
-
Transdermal dopaminergic D(2) receptor agonist therapy in Parkinson's disease with N-0923 TDS: a double-blind, placebo-controlled study
-
Hutton J.T., Metman L.V., Chase T.N., et al. Transdermal dopaminergic D(2) receptor agonist therapy in Parkinson's disease with N-0923 TDS: a double-blind, placebo-controlled study. Mov Disord 2001, 16(3):459-463.
-
(2001)
Mov Disord
, vol.16
, Issue.3
, pp. 459-463
-
-
Hutton, J.T.1
Metman, L.V.2
Chase, T.N.3
-
55
-
-
0034971541
-
Continuous transdermal dopaminergic stimulation in advanced Parkinson's disease
-
Metman L.V., Gillespie M., Farmer C., et al. Continuous transdermal dopaminergic stimulation in advanced Parkinson's disease. Clin Neuropharmacol 2001, 24(3):163-169.
-
(2001)
Clin Neuropharmacol
, vol.24
, Issue.3
, pp. 163-169
-
-
Metman, L.V.1
Gillespie, M.2
Farmer, C.3
-
56
-
-
70349302129
-
Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery
-
Cawello W., Braun M., Boekens H. Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery. Drug Metab Dispos 2009, 37(10):2055-2060.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.10
, pp. 2055-2060
-
-
Cawello, W.1
Braun, M.2
Boekens, H.3
-
57
-
-
34548825454
-
Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: a mass balance trial
-
Cawello W., Wolff H.M., Meuling W.J., et al. Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: a mass balance trial. Clin Pharm 2007, 46(10):851-857.
-
(2007)
Clin Pharm
, vol.46
, Issue.10
, pp. 851-857
-
-
Cawello, W.1
Wolff, H.M.2
Meuling, W.J.3
-
58
-
-
27644582306
-
Low drug-drug interaction potential of rotigotine
-
[abstract 1091]
-
Hansen K., Braun M., Horstmann R. Low drug-drug interaction potential of rotigotine. JClin Pharmacol 2005, 45. [abstract 1091].
-
(2005)
JClin Pharmacol
, vol.45
-
-
Hansen, K.1
Braun, M.2
Horstmann, R.3
-
59
-
-
0025978829
-
Impact of structural differences on theinvitro glucuronidation kinetics of potentially dopaminergic hydroxy-2-aminotetralins and naphthoxazines using rat and human liver microsomes
-
Swart P.J., Jansman F.G., Drenth B.F., et al. Impact of structural differences on theinvitro glucuronidation kinetics of potentially dopaminergic hydroxy-2-aminotetralins and naphthoxazines using rat and human liver microsomes. Pharmacol Toxicol 1991, 68(3):215-219.
-
(1991)
Pharmacol Toxicol
, vol.68
, Issue.3
, pp. 215-219
-
-
Swart, P.J.1
Jansman, F.G.2
Drenth, B.F.3
-
60
-
-
0028181472
-
Determination of the dopamine D2 agonist N-0923 and its major metabolites in perfused rat livers by HPLC-UV-atmospheric pressure ionization mass spectrometry
-
Swart P.J., Oelen W.E., Bruins A.P., et al. Determination of the dopamine D2 agonist N-0923 and its major metabolites in perfused rat livers by HPLC-UV-atmospheric pressure ionization mass spectrometry. JAnal Toxicol 1994, 18(2):71-77.
-
(1994)
JAnal Toxicol
, vol.18
, Issue.2
, pp. 71-77
-
-
Swart, P.J.1
Oelen, W.E.2
Bruins, A.P.3
-
61
-
-
36248987178
-
Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease
-
Baldwin C.M., Keating G.M. Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. CNS Drugs 2007, 21(12):1039-1055.
-
(2007)
CNS Drugs
, vol.21
, Issue.12
, pp. 1039-1055
-
-
Baldwin, C.M.1
Keating, G.M.2
-
62
-
-
79955022447
-
Challenges and opportunities in dermal/transdermal delivery
-
Paudel K.S., Milewski M., Swadley C.L., et al. Challenges and opportunities in dermal/transdermal delivery. Ther Deliv 2010, 1(1):109-131.
-
(2010)
Ther Deliv
, vol.1
, Issue.1
, pp. 109-131
-
-
Paudel, K.S.1
Milewski, M.2
Swadley, C.L.3
-
63
-
-
84881516450
-
-
Drug release characteristics of rotigotine transdermal system. Presented at the 33rd Annual Meeting, Exposition of the Controlled Release Society, Vienna, Austria, July 22-26
-
Wolff HM, Seiffert T, Boddenberg A, etal. Drug release characteristics of rotigotine transdermal system. Presented at the 33rd Annual Meeting, Exposition of the Controlled Release Society, Vienna, Austria, July 22-26, 2006.
-
(2006)
-
-
Wolff, H.M.1
Seiffert, T.2
Boddenberg, A.3
-
64
-
-
34547404736
-
Steady-state pharmacokinetics of rotigotine in patients with early-stage Parkinson's disease
-
[abstract P1245]
-
Braun M., Cawello W., Poole K., et al. Steady-state pharmacokinetics of rotigotine in patients with early-stage Parkinson's disease. Eur J Neurol 2005, 12(Suppl 2):96. [abstract P1245].
-
(2005)
Eur J Neurol
, vol.12
, Issue.SUPPL. 2
, pp. 96
-
-
Braun, M.1
Cawello, W.2
Poole, K.3
-
65
-
-
84859611783
-
Steady-state plasma concentration profile of transdermal rotigotine: an integrated analysis of three, open-label, randomized, phase I multiple dose studies
-
Elshoff J.P., Braun M., Andreas J.O., et al. Steady-state plasma concentration profile of transdermal rotigotine: an integrated analysis of three, open-label, randomized, phase I multiple dose studies. Clin Ther 2012, 34(4):966-978.
-
(2012)
Clin Ther
, vol.34
, Issue.4
, pp. 966-978
-
-
Elshoff, J.P.1
Braun, M.2
Andreas, J.O.3
-
66
-
-
84881486780
-
Stable plasma levels of rotigotine following transdermal patch removal and new patch application during long-term treatment of patients with advanced Parkinson's disease
-
Whitesides J., Cawello W., Woltering F., et al. Stable plasma levels of rotigotine following transdermal patch removal and new patch application during long-term treatment of patients with advanced Parkinson's disease. Neurology 2011, 76(Suppl 4):A275.
-
(2011)
Neurology
, vol.76
, Issue.SUPPL. 4
-
-
Whitesides, J.1
Cawello, W.2
Woltering, F.3
-
67
-
-
61349192144
-
Influence of domperidone on pharmacokinetics, safety and tolerability of the dopamine agonist rotigotine
-
Braun M., Cawello W., Boekens H., et al. Influence of domperidone on pharmacokinetics, safety and tolerability of the dopamine agonist rotigotine. Br J Clin Pharmacol 2009, 67(2):209-215.
-
(2009)
Br J Clin Pharmacol
, vol.67
, Issue.2
, pp. 209-215
-
-
Braun, M.1
Cawello, W.2
Boekens, H.3
-
68
-
-
69549135180
-
Lack of pharmacokinetic interactions between transdermal rotigotine and oral levodopa/carbidopa
-
Braun M., Cawello W., Andreas J.O., et al. Lack of pharmacokinetic interactions between transdermal rotigotine and oral levodopa/carbidopa. JClin Pharmacol 2009, 49(9):1047-1055.
-
(2009)
JClin Pharmacol
, vol.49
, Issue.9
, pp. 1047-1055
-
-
Braun, M.1
Cawello, W.2
Andreas, J.O.3
-
69
-
-
65649094112
-
Rotigotine transdermal delivery for the treatment of Parkinson's disease
-
Rascol O., Perez-Lloret S. Rotigotine transdermal delivery for the treatment of Parkinson's disease. Expert Opin Pharmacother 2009, 10(4):677-691.
-
(2009)
Expert Opin Pharmacother
, vol.10
, Issue.4
, pp. 677-691
-
-
Rascol, O.1
Perez-Lloret, S.2
-
70
-
-
34548844312
-
Pharmacokinetics, safety and tolerability of rotigotine after transdermal patch administration in Japanese and Caucasian healthy subjects
-
[abstract P9802]
-
Cawello W., Braun M., Horstmann R., et al. Pharmacokinetics, safety and tolerability of rotigotine after transdermal patch administration in Japanese and Caucasian healthy subjects. Mov Disord 2006, 21(Suppl 15):S547-S548. [abstract P9802].
-
(2006)
Mov Disord
, vol.21
, Issue.SUPPL. 15
-
-
Cawello, W.1
Braun, M.2
Horstmann, R.3
-
71
-
-
54249084223
-
Impact of moderate impairment of hepaticfunction on the steady-state pharmacokinetics of transdermal rotigotine
-
[abstract P2149]
-
Cawello W., Braun M., Horstmann R. Impact of moderate impairment of hepaticfunction on the steady-state pharmacokinetics of transdermal rotigotine. Eur J Neurol 2007, 14(Suppl 1):199. [abstract P2149].
-
(2007)
Eur J Neurol
, vol.14
, Issue.SUPPL. 1
, pp. 199
-
-
Cawello, W.1
Braun, M.2
Horstmann, R.3
-
72
-
-
83155173179
-
Single-dose pharmacokinetics of the transdermal rotigotine patch in patients with impaired renal function
-
Cawello W., Ahrweiler S., Sulowicz W., et al. Single-dose pharmacokinetics of the transdermal rotigotine patch in patients with impaired renal function. Br J Clin Pharmacol 2011, 10.1111/j.1365-2125.2011.04053.x.
-
(2011)
Br J Clin Pharmacol
-
-
Cawello, W.1
Ahrweiler, S.2
Sulowicz, W.3
-
73
-
-
0028031838
-
Pharmacokinetic characterisation of transdermal delivery systems
-
Berner B., John V.A. Pharmacokinetic characterisation of transdermal delivery systems. Clin Pharm 1994, 26(2):121-134.
-
(1994)
Clin Pharm
, vol.26
, Issue.2
, pp. 121-134
-
-
Berner, B.1
John, V.A.2
-
74
-
-
33947420950
-
The use of transdermal rotigotine in a patient with advanced Parkinson's disease and dysphagia
-
Christie J. The use of transdermal rotigotine in a patient with advanced Parkinson's disease and dysphagia. Palliat Med 2007, 21(2):163-164.
-
(2007)
Palliat Med
, vol.21
, Issue.2
, pp. 163-164
-
-
Christie, J.1
-
75
-
-
79958233594
-
Gastrointestinal disorders in Parkinson's disease: prevalence and health outcomes in a US claims database
-
Makaroff L., Gunn A., Gervasoni C., et al. Gastrointestinal disorders in Parkinson's disease: prevalence and health outcomes in a US claims database. JParkinsons Dis 2011, 1(1):65-74.
-
(2011)
JParkinsons Dis
, vol.1
, Issue.1
, pp. 65-74
-
-
Makaroff, L.1
Gunn, A.2
Gervasoni, C.3
-
76
-
-
0032801621
-
Postoperative complications in Parkinson's disease
-
Pepper P.V., Goldstein M.K. Postoperative complications in Parkinson's disease. JAm Geriatr Soc 1999, 47(8):967-972.
-
(1999)
JAm Geriatr Soc
, vol.47
, Issue.8
, pp. 967-972
-
-
Pepper, P.V.1
Goldstein, M.K.2
-
77
-
-
0035018919
-
Patient and carer perception of the management of Parkinson's disease after surgery
-
Barber M., Stewart D., Gr D., et al. Patient and carer perception of the management of Parkinson's disease after surgery. Age Ageing 2001, 30(2):171-172.
-
(2001)
Age Ageing
, vol.30
, Issue.2
, pp. 171-172
-
-
Barber, M.1
Stewart, D.2
Gr, D.3
-
78
-
-
1642268957
-
Movement disorder emergencies in the perioperative period
-
Frucht S.J. Movement disorder emergencies in the perioperative period. Neurol Clin 2004, 22(2):379-387.
-
(2004)
Neurol Clin
, vol.22
, Issue.2
, pp. 379-387
-
-
Frucht, S.J.1
-
79
-
-
77954535787
-
Transdermal rotigotine for the perioperative management of Parkinson's disease
-
Wüllner U., Kassubek J., Odin P., et al. Transdermal rotigotine for the perioperative management of Parkinson's disease. JNeural Transm 2010, 117(7):855-859.
-
(2010)
JNeural Transm
, vol.117
, Issue.7
, pp. 855-859
-
-
Wüllner, U.1
Kassubek, J.2
Odin, P.3
-
80
-
-
33846417336
-
Rotigotine transdermal system for perioperative administration
-
Korczyn A.D., Reichmann H., Boroojerdi B., et al. Rotigotine transdermal system for perioperative administration. JNeural Transm 2007, 114(2):219-221.
-
(2007)
JNeural Transm
, vol.114
, Issue.2
, pp. 219-221
-
-
Korczyn, A.D.1
Reichmann, H.2
Boroojerdi, B.3
-
81
-
-
74949137960
-
The clinically important difference on the unified Parkinson's disease rating scale
-
Shulman L.M., Gruber-Baldini A.L., Anderson K.E., et al. The clinically important difference on the unified Parkinson's disease rating scale. Arch Neurol 2010, 67(1):64-70.
-
(2010)
Arch Neurol
, vol.67
, Issue.1
, pp. 64-70
-
-
Shulman, L.M.1
Gruber-Baldini, A.L.2
Anderson, K.E.3
-
82
-
-
57049135288
-
Crystallisation within transdermal rotigotine patch: is there cause for concern?
-
Chaudhuri K.R. Crystallisation within transdermal rotigotine patch: is there cause for concern?. Expert Opin Drug Deliv 2008, 5(11):1169-1171.
-
(2008)
Expert Opin Drug Deliv
, vol.5
, Issue.11
, pp. 1169-1171
-
-
Chaudhuri, K.R.1
-
83
-
-
84881502281
-
-
US National Institutes of Health, National Library of Medicine, Bethesda (MD), Available at:, Accessed May 15, 2013
-
US National Institutes of Health Study in healthy volunteers to prove that two different formulations of rotigotine patches deliver equivalent drug amount to the body 2011, National Library of Medicine, Bethesda (MD), Available at:, Accessed May 15, 2013. http://clinicaltrials.gov/ct2/show/NCT01059903.
-
(2011)
Study in healthy volunteers to prove that two different formulations of rotigotine patches deliver equivalent drug amount to the body
-
-
|