All-trans retinoic acid modulates mitogen-activated protein kinase pathway activation in human scleral fibroblasts through retinoic acid receptor beta

Molecular Vision

Volumn 19, Issue , 2013, Pages 1795-1803

  Huo, Lijun ^a,b   Cui, Dongmei ^a   Yang, Xiao ^a   Gao, Zhenya ^a   Trier, Klaus ^c   Zeng, Junwen ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c Trier Research Laboratories   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C JUN; RETINOIC ACID; RETINOIC ACID DERIVATIVE; RETINOIC ACID RECEPTOR BETA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

CELL SHAPE; CELLS, CULTURED; DIBENZAZEPINES; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, RETINOIC ACID; SCLERA; TRETINOIN;

EID: 84881512255     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. He M, Zeng J, Liu Y, Xu J, Pokharel GP, Ellwein LB. Refractive error and visual impairment in urban children in southern china. Invest Ophthalmol Vis Sci 2004; 45:793-9. [PMID: 14985292].
2. Chang L, Pan CW, Ohno-Matsui K, Lin X, Lin X, Cheung GC, Gazzard G, Koh V, Hamzah H, Tai ES, Lim SC, Mitchell P, Young TL, Aung T, Wong TY, Saw SM. Myopia-related fundus changes in singapore adults with high myopia. Am J Ophthalmol 2013; 155:991-9. [PMID: 23499368].
3. Kusakari T, Sato T, Tokoro T. Regional scleral changes in form-deprivation myopia in chicks. Exp Eye Res 1997; 64:465-76. [PMID: 9196399].
4. McBrien NA, Cornell LM, Gentle A. Structural and ultrastructural changes to the sclera in a mammalian model of high myopia. Invest Ophthalmol Vis Sci 2001; 42:2179-87. [PMID: 11527928].
5. McBrien NA, Lawlor P, Gentle A. Scleral remodeling during the development of 16 and recovery from axial myopia in the tree shrew. Invest Ophthalmol Vis Sci 2000; 41:3713-9. [PMID: 11053267].
6. Means AL, Gudas LJ. The roles of retinoids in vertebrate development. Annu Rev Biochem 1995; 64:201-33. [PMID: 7574480].
7. McFadden SA, Howlett MH, Mertz JR. Retinoic acid signals the direction of ocular elongation in the guinea pig eye. Vision Res 2004; 44:643-53. [PMID: 14751549].
8. Mertz JR, Wallman J. Choroidal retinoic acid synthesis: a possible mediator between refractive error and compensatory eye growth. Exp Eye Res 2000; 70:519-27. [PMID: 10866000].
9. Yan DS, Zhou XT, Chen XY, Lu F, Wang J, Hu DN, Qu J. Expression of retinoid acid receptors in human scleral fibroblasts and regulation of growth of fibroblasts by retinoic acidZhonghua Yan Ke Za Zhi 2007; 43:750-3. [PMID: 18001576].
10. Li C, McFadden SA, Morgan I, Cui D, Hu J, Wan W, Zeng J. All-trans retinoic acid regulates the expression of the extracellular matrix protein fibulin-1 in the guinea pig sclera and human scleral fibroblasts. Mol Vis 2010; 16:689-97. [PMID: 20405022].
11. Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996; 10:940-54. [PMID: 8801176].
12. Cvekl A, Wang WL. Retinoic acid signaling in mammalian eye development. Exp Eye Res 2009; 89:280-91. [PMID: 19427305].
13. Zheng B, Han M, Bernier M, Zhang XH, Meng F, Miao SB, He M, Zhao XM, Wen JK. Kruppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, 17 phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells. J Biol Chem 2009; 284:22773-85. [PMID: 19531492].
14. Chung J, Liu C, Smith DE, Seitz HK, Russell RM, Wang XD. Restoration of retinoic acid concentration suppresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver. Carcinogenesis 2001; 22:1213-9. [PMID: 11470752].
15. Li Y, Hashimoto Y, Agadir A, Kagechika H, Zhang X. Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells. J Biol Chem 1999; 274:15360-6. [PMID: 10336422].
16. Li Z, Yao SJ, Alini M, Stoddart MJ. The role of retinoic acid receptor inhibitor LE135 on the osteochondral differentiation of human bone marrow mesenchymal stem cells. J Cell Biochem 2011; 112:963-70. [PMID: 21308729].
17. Sasaki Y, Iwai N, Kimura O, Ono S, Tsuda T, Deguchi E. Establishment of a rescue program for anorectal malformations induced by retinoic acid in mice. J Pediatr Surg 2011; 46:1396-9. [PMID: 21763841].
18. Cui D, Trier K, Chen X, Zeng J, Yang X, Hu J, Ge J. Distribution of adenosine receptors in human sclera fibroblasts. Mol Vis 2008; 14:523-9. [PMID: 18385786].
19. Wu WC, Hu DN, Mehta S, Chang YC. Effects of retinoic acid on retinal pigment epithelium from excised membranes from proliferative vitreoretinopathy. J Ocul Pharmacol Ther 2005; 21:44-54. [PMID: 15718827].
20. Ubels JL, Wertz JT, Ingersoll KE, Jackson RN, Aupperlee MD. Down-regulation of androgen receptor expression and inhibition of lacrimal gland cell proliferation by retinoic acid. Exp Eye Res 2002; 75:561-71. [PMID: 12457868].
21. Siddikuzzaman, Berlin GV. All trans retinoic acid and cancer. Immunopharmacol Immunotoxicol 2011; 33:241-9. [PMID: 20929432].
22. Dalvin S, Komatsuzaki K, Anselmo MA, Kling DE, Schnitzer JJ, Kinane TB. Retinoic acid decreases fetal lung mesenchymal cell proliferation in vivo and in vitro. Dev Growth Differ 2004; 46:275-82. [PMID: 15206958].
23. Zhang H, Rosdahl I. Expression of p27 and MAPK proteins involved in all-trans retinoic acid-induced apoptosis and cell cycle arrest in matched primary and metastatic melanoma cells. Int J Oncol 2004; 25:1241-8. [PMID: 15492811].
24. Pettersson F, Couture MC, Hanna N, Miller WH. Enhanced retinoid-induced apoptosis of MDA-MB-231 breast cancer cells by PKC inhibitors involves activation of ERK. Oncogene 2004; 23:7053-66. [PMID: 15273718].
25. Cheepala SB, Yin W, Syed Z, Gill JN, McMillian A, Kleiner HE, Lynch M, Loganantharaj R, Trutschl M, Cvek U, Clifford JL. Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion. Mol Cancer 2009; 8:27 [PMID: 19432991].
26. Syed Z, Cheepala SB, Gill JN, Stein J, Nathan C, Digiovanni J, Batra V, Adegboyega P, Kleiner HE, Clifford JL. All-trans retinoic acid suppresses Stat3 signaling during skin carcinogenesis. Cancer Prev Res (Phila) 2009; 2:903-11. [PMID: 19789299].
27. Ren X, Ma X, Li Y. All-trans retinoic acid regulates c-jun expression via ERK5 in cardiac myoblasts. J Nutr Biochem 2007; 18:832-8. [PMID: 17509854].
28. Alsayed Y, Uddin S, Mahmud N, Lekmine F, Kalvakolanu DV, Minucci S, Bokoch G, Platanias LC. Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid. J Biol Chem 2001; 276:4012-9. [PMID: 11060298].
29. Dai X, Yamasaki K, Shirakata Y, Sayama K, Hashimoto K. All-trans-retinoic acid induces interleukin-8 via the nuclear factor-kappaB and p38 mitogen-activated protein kinase pathways in normal human keratinocytes. J Invest Dermatol 2004; 123:1078-85. [PMID: 15610518].
30. Ren X, Li Y, Ma X, Zheng L, Xu Y, Wang J. Activation of p38/MEF2C pathway by all-trans retinoic acid in cardiac myoblasts. Life Sci 2007; 81:89-96. [PMID: 17568621].
31. Martinović V, Grigorov I, Bogojević D, Petrović A, Jovanović S, Ilic M, Ivanović Matic S. Activation Level of JNK and Akt/ERK Signaling Pathways Determinates Extent of DNA Damage in the Liver of Diabetic Rats. Cell Physiol Biochem 2012; 30:723-34. [PMID: 22854746].
32. Kafienah W, Mistry S, Perry MJ, Politopoulou G, Hollander AP. Pharmacological regulation of adult stem cells: chondrogenesis can be induced using a synthetic inhibitor of the retinoic acid receptor. Stem Cells 2007; 25:2460-8. [PMID: 17615267].
33. Huang J, Qu XM, Chu RY. Expressions of cellular retinoic acid binding proteins I and retinoic acid receptor-beta in the guinea pig eyes with experimental myopia. Int J Ophthalmol 2011; 4:131-6. [PMID: 22553627].
34. Troilo D, Nickla DL, Mertz JR, Summers RJ. Change in the synthesis rates of ocular retinoic acid and scleral glycosaminoglycan during experimentally altered eye growth in marmosets. Invest Ophthalmol Vis Sci 2006; 47:1768-77. [PMID: 16638980].
35. Nishimoto S, Nishida E. MAPK signalling: ERK5 versus ERK1/2. EMBO Rep 2006; 7:782-6. [PMID: 16880823].