Working memory impairment in pilots exposed to acute hypobaric hypoxia

Aviation Space and Environmental Medicine

Volumn 84, Issue 8, 2013, Pages 773-779

  Malle, Carine ^a   Quinette, Peggy ^a   Laisney, Mickaël ^a   Bourrilhon, Cyprien ^a   Boissin, Jacqueline ^a   Desgranges, Beatrice ^a   Eustache, Francis ^a   Piérard, Christophe ^a  

^a INSERM   (France)

Author keywords

Altitude; Hypobaric chamber; Hypoxia training .; PASAT; Pilot performance

Indexed keywords

OXYGEN;

ADULT; AEROSPACE MEDICINE; AIR QUALITY CONTROL; ALTITUDE DISEASE; ARTICLE; BLOOD; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HEART RATE; HUMAN; MALE; MEMORY DISORDER; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SHORT TERM MEMORY;

ADULT; AEROSPACE MEDICINE; ALTITUDE SICKNESS; ATMOSPHERE EXPOSURE CHAMBERS; HEART RATE; HUMANS; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; OXYGEN;

EID: 84881492550     PISSN: 00956562     EISSN: None     Source Type: Journal    
DOI: 10.3357/ASEM.3482.2013     Document Type: Article

References (35)

1. Baddeley A . Working memory . Science 1992 ; 255 : 556-9 .
2. Baddeley AD, Hitch GJ . L Working Memory . In : Bower GA , ed . The psychology of learning and motivation: advances in research and theory . New York : Academic Press ; 1974 : 47-89 .
3. Barak Y, David D, Keselbrener L, Akselrod S . Autonomic response to hypobaric hypoxia assessed by time-dependent frequency decomposition of heart rate . Aviat Space Environ Med 2001 ; 72 : 992-1000 .
4. Cable GG . In-fl ight hypoxia incidents in military aircraft: causes and implications for training . Aviat Space Environ Med 2003 ; 74 : 169-72 .
5. Campagna JA, Carter C. Clinical relevance of the Bezold-Jarisch refl ex . Anesthesiology 2003 ; 98 : 1250-60 .
6. Crow TJ, Kelman GR . Effect of mild acute hypoxia on human short-term memory . Br J Anaesth 1971 ; 43 : 548-52 .
7. D'Esposito M, Detre JA, Alsop DC, Shin RK, Atlas S, Grossman M . The neural basis of the central executive system of working memory . Nature 1995 ; 378 : 279-81 .
8. D'Esposito M, Postle BR, Rypma B . Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies . Exp Brain Res 2000 ; 133 : 3-11 .
9. DeHart RL, Davis JR . Fundamentals of Aerospace Medicine, 3rd ed . Philadelphia : Lippincott Williams & Wilkins ; 2002 .
10. Ernsting J, Sharp G, Harding R . Hypoxia and hyperventialtion . In : Ernsting J, King P , eds . Aviation Medicine, 2nd ed . Oxford : Butterworth Heinemann ; 1988 : 45 - 59 .
11. Files DS, Webb JT, Pilmanis AA . Depressurization in military aircraft: rates, rapidity, and health effects for 1055 incidents . Aviat Space Environ Med 2005 ; 76 : 523-9 .
12. Forn C, Barros-Loscertales A, Escudero J, Belloch V, Campos S, et al. Cortical reorganization during PASAT task in MS patients with preserved working memory functions . Neuroimage 2006 ; 31 : 686-91 .
13. Fowler B, Grant A . Hearing thresholds under acute hypoxia and relationship to slowing in the auditory modality . Aviat Space Environ Med 2000 ; 71 : 946-9 .
14. Fowler B, Prlic H, Brabant M . Acute hypoxia fails to infl uence two aspects of short-term memory: implications for the source of cognitive defi cits . Aviat Space Environ Med 1994 ; 65 : 641-5 .
15. Gronwall D, Sampson H . The psychological effects of concussion . Auckland : Auckland University Press ; 1974 .
16. Harding R . Hypoxia and hyperventilation . In : Ernsting J, Nicholson AN, Rainford DJ , eds. Aviation Medicine . Oxford : Butterworth Heinemann ; 1999 : 43 - 58 .
17. Kraaier V, van Huffelen AC, Wieneke GH . The hyperventilationinduced ischaemia model in human neuropharmacology: neurophysiological and psychometric studies of aniracetam and 3-OH aniracetam . Eur J Clin Pharmacol 1989 ; 36 : 605-11 .
18. Lindholm P, Blogg SL, Gennser M . Pulse oximetry to detect hypoxemia during apnea: comparison of fi nger and ear probes . Aviat Space Environ Med 2007 ; 78 : 770-3 .
19. Mazza S, Pepin JL, Naegele B, Plante J, Deschaux C, Levy P . Most obstructive sleep apnoea patients exhibit vigilance and attention defi cits on an extended battery of tests . Eur Respir J 2005 ; 25 : 75-80 .
20. McFarland R . The effects of altitude on pilot performance . Hannisdahl B, Sem-Jacobsen C , eds. Aviation and space medicine . Oslo : Universitetsforlaget 1969 : 96 - 108 .
21. Morris N, Jones DM . Habituation to irrelevant speech: effects on a visual short-term memory task . Percept Psychophys 1990 ; 47 : 291-7 .
22. NATO. STANAG 3114, Aeromedical training of flight personnel. Edition 82006. Brussels, Belgium: Military Agency for Standardization; no date .
23. NATO. STANAG 7056, Functional requirements for physiological protection during high altitude parachuting operations. Edition 11997. Brussels, Belgium: Military Agency for Standardization; no date .
24. Petrides M, Alivisatos B, Meyer E, Evans AC . Functional activation of the human frontal cortex during the performance of verbal working memory tasks . Proc Natl Acad Sci USA 1993 ; 90 : 878-82 .
25. Saletu B, Grunberger J, Anderer R . On brain protection of codergocrine mesylate (Hydergine) against hypoxic hypoxidosis of different severity: double-blind placebo-controlled quantitative EEG and psychometric studies . Int J Clin Pharmacol Ther Toxicol 1990; 28: 510-24.
26. Severinghaus JW, Naifeh KH . Accuracy of response of six pulse oximeters to profound hypoxia. Anesthesiology 1987; 67: 551-8.
27. Smith AM . Hypoxia symptoms in military aircrew: long-term recall vs. acute experience in training . Aviat Space Environ Med 2008 ; 79 : 54-7 .
28. Spielberger CD, Gorssuch RL, Lushene PR, Vagg PR, Jacobs GA . Manual for the State-Trait Anxiety Inventory . Mountain View, CA : Consulting Psychologist Press, Inc. ; 1983 .
29. Tombaugh TN . A comprehensive review of the Paced Auditory Serial Addition Test (PASAT) . Arch Clin Neuropsychol 2006 ; 21 : 53-76 .
30. van der Post J, Noordzij LA, de Kam ML, Blauw GJ, Cohen AF, van Gerven JM . Evaluation of tests of central nervous system performance after hypoxemia for a model for cognitive impairment . J Psychopharmacol 2002 ; 16 : 337-43 .
31. Van der Worp HB, Kraaier V, Wieneke GH, Van Huffelen AC . Quantitative EEG during progressive hypocarbia and hypoxia. Hyperventilation-induced EEG changes reconsidered . Electroencephalogr Clin Neurophysiol 1991 ; 79 : 335-41 .
32. Wagner JL, Ruskin KJ . Pulse oximetry: basic principles and applications in aerospace medicine . Aviat Space Environ Med 2007 ; 78 : 973-8 .
33. Wingenfeld SA, Holdwick, DJ, Jr., Davis JL, Hunter BB . Normative data on computerized paced auditory serial addition task performance . Clin Neuropsychol 1999 : 13 : 268-73 .
34. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects, (2008) .
35. Woodrow AD, Webb JT, Wier GS . Recollection of hypoxia symptoms between training events . Aviat Space Environ Med . 2011 ; 82 : 1143 - 7 .