-
1
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001; 98: 2301-2307.
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
Grimes, B.4
Howard, D.S.5
Rizzieri, D.A.6
-
2
-
-
0037059012
-
Preferential induction of apoptosis for primary human leukemic stem cells
-
DOI 10.1073/pnas.252462599
-
Guzman ML, Swiderski CF, Howard DS, Grimes BA, Rossi RA, Szilvassy SJ et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proc Natl Acad Sci USA 2002; 99: 16220-16225. (Pubitemid 35462776)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16220-16225
-
-
Guzman, M.L.1
Swiderski, C.F.2
Howard, D.S.3
Grimes, B.A.4
Rossi, R.M.5
Szilvassy, S.J.6
Jordan, C.T.7
-
3
-
-
34848866258
-
M4 and M5 acute myeloid leukaemias display a high sensitivity to Bortezomib-mediated apoptosis
-
DOI 10.1111/j.1365-2141.2007.06757.x
-
Riccioni R, Senese M, Diverio D, Riti V, Buffolino S, Mariani G et al. M4 and M5 acute myeloid leukaemias display a high sensitivity to Bortezomib-mediated apoptosis. Br J Haematol 2007; 139: 194-205. (Pubitemid 47493077)
-
(2007)
British Journal of Haematology
, vol.139
, Issue.2
, pp. 194-205
-
-
Riccioni, R.1
Senese, M.2
Diverio, D.3
Riti, V.4
Buffolino, S.5
Mariani, G.6
Boe, A.7
Cedrone, M.8
Lo-Coco, F.9
Foa, R.10
Peschle, C.11
Testa, U.12
-
4
-
-
34248377893
-
Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms and p53 status
-
DOI 10.1007/s00280-006-0367-6
-
Minderman H, Zhou Y, O'Loughlin KL, Baer MR. Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms and p53 status. Cancer Chemother Pharmacol 2007; 60: 245-255. (Pubitemid 46742540)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.60
, Issue.2
, pp. 245-255
-
-
Minderman, H.1
Zhou, Y.2
O'Loughlin, K.L.3
Baer, M.R.4
-
5
-
-
2542481724
-
Phase I study of bortezomib in refractory of relapsed acute leukemias
-
DOI 10.1158/1078-0432.CCR-03-0508
-
Cortes J, Thomas D, Koller C, Giles F, Estey E, Faderl S et al. Phase I study of borte-zomib in refractory or relapsed acute leukemias. Clin Cancer Res 2004; 10: 3371-3376. (Pubitemid 38685442)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.10
, pp. 3371-3376
-
-
Cortes, J.1
Thomas, D.2
Koller, C.3
Giles, F.4
Estey, E.5
Faderl, S.6
Garcia-Manero, G.7
McConkey, D.8
Patel, G.9
Guerciolini, R.10
Wright, J.11
Kantarjian, H.12
-
6
-
-
20144387627
-
Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
-
Orlowski RZ, Voorhees PM, Garcia RA, Hall MD, Kurdik FJ, Allred T et al. Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 2005; 105: 3058-3065.
-
(2005)
Blood
, vol.105
, pp. 3058-3065
-
-
Orlowski, R.Z.1
Voorhees, P.M.2
Garcia, R.A.3
Hall, M.D.4
Kurdik, F.J.5
Allred, T.6
-
7
-
-
38949096781
-
Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes
-
DOI 10.1182/blood-2007-06-098061
-
Garcia-Manero G, Yang H, Bueso-Ramos C, Ferrajoli A, Cortes J, Wierda WG et al. Phase I study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) in patients with advanced leukemias and myelodys-plastic syndromes. Blood 2008; 111: 1060-1066. (Pubitemid 351213383)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1060-1066
-
-
Garcia-Manero, G.1
Yang, H.2
Bueso-Ramos, C.3
Ferrajoli, A.4
Cortes, J.5
Wierda, W.G.6
Faderl, S.7
Koller, C.8
Morris, G.9
Rosner, G.10
Loboda, A.11
Fantin, V.R.12
Randolph, S.S.13
Hardwick, J.S.14
Reilly, J.F.15
Chen, C.16
Ricker, J.L.17
Secrist, J.P.18
Richon, V.M.19
Frankel, S.R.20
Kantarjian, H.M.21
more..
-
8
-
-
33947581039
-
Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias
-
DOI 10.1182/blood-2006-05-021873
-
Gojo I, Jiemjit A, Trepel JB, Sparreboom A, Figg WD, Rollins S et al. Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias. Blood 2007; 109: 2781-2790. (Pubitemid 46482071)
-
(2007)
Blood
, vol.109
, Issue.7
, pp. 2781-2790
-
-
Gojo, I.1
Jiemjit, A.2
Trepel, J.B.3
Sparreboom, A.4
Figg, W.D.5
Rollins, S.6
Tidwell, M.L.7
Greer, J.8
Eun, J.C.9
Lee, M.-J.10
Gore, S.D.11
Sausville, E.A.12
Zwiebel, J.13
Karp, J.E.14
-
9
-
-
38049126172
-
Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma
-
Heider U, von Metzler I, Kaiser M, Rosche M, Sterz J, Rotzer S et al. Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma. Eur J Haematol 2008; 80: 133-142.
-
(2008)
Eur J Haematol
, vol.80
, pp. 133-142
-
-
Heider, U.1
Von Metzler, I.2
Kaiser, M.3
Rosche, M.4
Sterz, J.5
Rotzer, S.6
-
10
-
-
34249993174
-
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib
-
DOI 10.1007/s10495-007-0063-y
-
Emanuele S, Lauricella M, Carlisi D, Vassallo B, D'Anneo A, Di Fazio P et al. SAHA induces apoptosis in hepatoma cells and synergistically interacts with the pro-teasome inhibitor Bortezomib. Apoptosis 2007; 12: 1327-1338. (Pubitemid 46890392)
-
(2007)
Apoptosis
, vol.12
, Issue.7
, pp. 1327-1338
-
-
Emanuele, S.1
Lauricella, M.2
Carlisi, D.3
Vassallo, B.4
D'Anneo, A.5
Di Fazio, P.6
Vento, R.7
Tesoriere, G.8
-
11
-
-
84862239485
-
A Phase II trial of bortezomib and vorinostat in mantle cell lymphoma and diffuse large b-cell lymphoma
-
ASH abstract 779
-
Holkova B, Perkins EB, Sokol L, Richards KL, Parekh S, Elstrom R et al. A Phase II trial of bortezomib and vorinostat in mantle cell lymphoma and diffuse large b-cell lymphoma. Blood 2011; 118: ASH abstract 779.
-
(2011)
Blood
, vol.118
-
-
Holkova, B.1
Perkins, E.B.2
Sokol, L.3
Richards, K.L.4
Parekh, S.5
Elstrom, R.6
-
12
-
-
84867422068
-
Phase i trial of vorinostat combined with bortezomib for the treatment of relapsing and/or refractory multiple myeloma
-
Weber DM, Graef T, Hussein M, Sobecks RM, Schiller GJ, Lupinacci L et al. Phase I trial of vorinostat combined with bortezomib for the treatment of relapsing and/or refractory multiple myeloma. Clin Lymphoma Myeloma Leuk 2012; 12: 319-324.
-
(2012)
Clin Lymphoma Myeloma Leuk
, vol.12
, pp. 319-324
-
-
Weber, D.M.1
Graef, T.2
Hussein, M.3
Sobecks, R.M.4
Schiller, G.J.5
Lupinacci, L.6
-
13
-
-
84859538161
-
Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: A north central cancer group study
-
Friday BB, Anderson SK, Buckner J, Yu C, Giannini C, Geoffroy F et al. Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer group study. Neuro Oncol 2012; 14: 215-221.
-
(2012)
Neuro Oncol
, vol.14
, pp. 215-221
-
-
Friday, B.B.1
Anderson, S.K.2
Buckner, J.3
Yu, C.4
Giannini, C.5
Geoffroy, F.6
-
14
-
-
84859719940
-
Vantage 088: Vorinostat in combination with bortezomib in patients with refractory/relapsed multiple myeloma: Results of a global, randomized phase 3 trial
-
ASH abstract 811
-
Dimopoulos MA, Jagannath S, Yoon S, Siegel D, Lonial S. Vantage 088: vorinostat in combination with bortezomib in patients with refractory/relapsed multiple myeloma: results of a global, randomized phase 3 trial. Blood 2011; 118: ASH abstract 811.
-
(2011)
Blood
, vol.118
-
-
Dimopoulos, M.A.1
Jagannath, S.2
Yoon, S.3
Siegel, D.4
Lonial, S.5
-
15
-
-
84861804180
-
Vantage 095: Vorinostat in combination with bortezomib in salvage multiple myeloma patients: Final study results of a global phase 2b trial
-
ASH abstract 480
-
Siegel D, Dimonopoulos, Yoon S, Laubach J, Kaufman J. Vantage 095: vorinostat in combination with bortezomib in salvage multiple myeloma patients: final study results of a global phase 2b trial. Blood 2011; 118: ASH abstract 480.
-
(2011)
Blood
, vol.118
-
-
Siegel, D.1
Dimonopoulos Yoon, S.2
Laubach, J.3
Kaufman, J.4
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