Interleukin-12b gene polymorphism frequencies in Egyptians and sex-related susceptibility to hepatitis c infection

Journal of Interferon and Cytokine Research

Volumn 33, Issue 8, 2013, Pages 415-419

  Youssef, Samar Samir ^a   Mostafa, Asmaa ^a   Nasr, Amal Soliman ^b   El Zanaty, Taher ^c   Seif, Sameh Mohamed ^d  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c CAIRO UNIVERSITY   (Egypt)

^d NATIONAL HEPATOLOGY AND TROPICAL MEDICINE RESEARCH INSTITUTE   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12P40;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENE FREQUENCY; GENOTYPE; HEPATITIS C; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

HEPATITIS C VIRUS;

ADULT; ANTIBODIES, VIRAL; EGYPT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPACIVIRUS; HEPATITIS C; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERLEUKIN-12 SUBUNIT P40; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS;

EID: 84881448144     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2012.0161     Document Type: Article

References (35)

1. Alter HJ, Conry-Cantilena C, Melpolder J, Tan D, Van Raden M, et al. 1997 Hepatitis C in asymptomatic blood donors. Hepatology 26:29S-33S (Pubitemid 27388068)
2. Alter M, Gerety R, Smallwood L, Sampliner RE, Tabor E, et al. 1982 Sporadic non-A, non-B hepatitis: frequency and epidemiology in an urban U.S. population. J Infect Dis 145:886-893 (Pubitemid 12088968)
3. Bergholdt R, Ghandil P, Johannesen J, Kristiansen OP, Kockum I, et al. 2004 Genetic and functional evaluation of an interleukin- 12 polymorphism (IDDM18) in families with type 1 diabetes. J Med Genet 41:39
4. CDC. 2011. Antiviral agents for the treatment and chemoprophylaxis of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 60(No. RR-1)
5. CDC. 2012 Update: influenza A (H3N2)v transmission and guidelines - five states, 2011. MMWR 60:1741-1744
6. Council of State and Territorial Epidemiologists. 2007 National reporting for initial detections of novel influenza A viruses. Position statement 07-ID01
7. Atlanta, GA: Council of State and Territorial Epidemiologists. Available at www.cste.org/ps/ 2007ps/2007psfinal/id/07-id-01.pdf
8. Garci'a-Gonza'lez MA, Lanas A, Wu J, Benito R, Santolaria S, et al. 2005. Lack of association of IL-12 p40 gene polymorphism with peptic ulcer disease. Hum Immunol 66(1):72-76 (Pubitemid 40037714)
9. Gramenzi A, Andreone P, Loggi E, Foschi FG, Cursaro C, et al. 2005 Cytokine profile of peripheral blood mononuclear cell from patients with different outcomes of hepatitis C virus infection. J Viral Hepat 12:525-530 (Pubitemid 41224258)
10. Hannah MF, Bajic VB, Klein SL. 2008 Sex differences in the recognition of and innate antiviral responses to Seoul virus in Norway rats. Brain Behav Immun 22:503-516 (Pubitemid 351451824)
11. Hegazy D, Thurairajah P, Metzner M, Houldsworth A, Shaw S, et al. 2008 Interleukin 12B gene polymorphism and apparent resistance to hepatitis C virus infection. Clin Exp Immunol 152:538-541 (Pubitemid 351661506)
12. Hill AV. 1998 The immunogenetics of human infectious diseases. Annu Rev Immunol 16:593-617 (Pubitemid 28183378)
13. Houldsworth A, Metzner M, Rossol S, Shaw S, Kaminski E, et al. 2005 Polymorphisms in the il12B gene and outcome of HCV infection. J Interferon Cytokine Res 25:271-276 (Pubitemid 40664424)
14. Huang D, Cancilla MR, Morahan G. 2000. Complete primary structure, chromosomal localization and definition of polymorphisms of the gene encoding the human interleukn-12 p40 subunit. Genes Immun 1:515-520
15. Huang SH, Frydas S, Conti P, Kempuraj D, Barbacane RC, et al. 2004. Interleukin-17: a revisited study. Int J Immunopathol Pharmacol 17:1-4 (Pubitemid 39572181)
16. Kempuraj D, Donelan J, Frydas S, Iezzi T, Conti F, et al. 2004. Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities. Int J Immunopathol Pharmacol 17: 103-106 (Pubitemid 39572165)
17. Klein SL. 2000. The effects of hormones on sex differences in infection: from genes to behavior. Neurosci Biobehav Rev 24:627-638 (Pubitemid 30625129)
18. Koziel MJ. 1999. Cytokines in viral hepatitis. Seminar Liver Dis 2:157-168
19. Le Cam A, Legraverend C. 1995. Transcriptional repression, a novel function for 3¢ untranslated regions. Eur J Biochem 231:620-627
20. Miller SA, Dykes DD, Polesky HF. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16(3):1215
21. Morahan G, Huang D, Wu M, Holt BJ, White GP, et al. 2002. Association of IL12B promoter polymorphism with severity of atopic and non-Atopic asthma in children. Lancet 360:455-459 (Pubitemid 34880144)
22. Morahan G, Huang D, Ymer SI, Cancilla MR, Stephen K, et al. 2001. Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele. Nat Genet 27: 218-221 (Pubitemid 32157453)
23. Mueller T, Mas-Marques A, Sarrazin C, Wiese M, Halangk J, et al. 2004. Influence of interleukin 12B (IL-12B) polymorphisms on spontaneous and treatment-induced recovery from hepatitis C virus infection. J Hepatol 41:652-658 (Pubitemid 39297802)
24. Petrarca C, Frydas S, Donelan J, Boucher W, Papadopoulou N, et al. 2005. Interleukin 27 (IL-27): A novel pleiotropic cytokine involved in T cell differentiation and T cell response modulation. Int J Immunopathol Pharmacol 18:191-194 (Pubitemid 40825881)
25. Piazzolla G, Tortorella C, Fiore G, Fanelli M, PiscontiI A, et al. 2001. Interleukin-12 p40/p70 ratio and in vivo responsiveness to IFN- treatment in chronic hepatitis C. J Interferon Cytokine Res 21:453-461
26. Rodger AJ, Roberts S, Lanigan A, Bowden S, Brown T, et al. 2000. Assessment of longterm outcomes of communityacquired hepatitis C infection in a cohort with sera stored from 1971 to 1975. Hepatology 32:582-587
27. Schlaak JF, Pitz T, Lohr HF, Meyer ZM, Buschenfelde KH, et al. 1998. Interleukin 12 enhances deficient HCV-Antigen-induced Th1-type immune response of peripheral blood mononuclear cells. J Med Virol 56:112-117 (Pubitemid 28419270)
28. Seegers D, Zwiers A, Strober W, Pena AS, Bouma GA. 2002. Taq1 polymorphism in the 3¢UTR of the Il-12 p40 gene correlates with increased Il-12 secretion. Genes Immun 3:419-423 (Pubitemid 41656541)
29. Sieburth D, Jabs EW, Warrington JA, Li X, Lasota J, et al. 1992. Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5. Genomics 14:59-62
30. Suneetha PV, Goyal A, Hissar S, Sarin SK. 2006. Studies on TAQ1 polymorphism in the 3'untranslated region of IL-12P40 gene in HCV patients infected predominantly with genotype 3. J Med Virol 78(8):1055-1060
31. Van Dyke AL, Cote ML, Wenzlaff AS, Land S, Schwartz AG. 2009. Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies. Cytokine 46(2):236-244
32. Van Veen T, Crusius JB, Schrijver HM, Bouma G, Killestein J, et al. 2001. Interleukin-12p40 genotype plays a role in the susceptibility to multiple sclerosis. Ann Neurol 50:275-279
33. Wan L, Kung YJ, Lin YJ, Liao CC, Sheu JJ, et al. 2009. Th1 and Th2 cytokines are elevated in HCV-infected SVR(-) patients treated with interferon-A. Biochem Biophys Res Commun 379:855-860
34. World Health Organization. 2008. International health regulations (2005), Second edition. Geneva, Switzerland: World Health Organization. Available at http://whqlibdoc.who.int/ publications/2008/9789241580410-eng.pdf
35. Yin LM, Zhu WF, Wei L, Xu XY, Sun DG, et al. 2004. Association of interleukin-12 p40 gene 3¢-untranslated region polymorphism and outcome of HCV infection. World J Gastroenterol 10:2330-2333. (Pubitemid 39157754)