Decreased functional connectivity between the amygdala and the left ventral prefrontal cortex in treatment-naive patients with major depressive disorder: A resting-state functional magnetic resonance imaging study

Psychological Medicine

Volumn 43, Issue 9, 2013, Pages 1921-1927

  Tang, Y ^a   Kong, L ^a   Wu, F ^a   Womer, F ^b   Jiang, W ^a   Cao, Y ^c   Ren, L ^a   Wang, J ^d   Fan, G ^a   Blumberg, H P ^e   Xu, K ^a   Wang, F ^a,e  

^a CHINA MEDICAL UNIVERSITY   (China)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Shenyang Mental Health Center   (China)

^d HANGZHOU NORMAL UNIVERSITY   (China)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amygdala; functional connectivity; functional magnetic resonance; major depressive disorder; resting state; ventral prefrontal cortex

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN; FEMALE; FUNCTIONAL NEUROIMAGING; HUMAN; MAJOR DEPRESSION; MALE; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; YOUNG ADULT;

ADULT; AMYGDALA; BRAIN; DEPRESSIVE DISORDER, MAJOR; FEMALE; FUNCTIONAL NEUROIMAGING; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 84881435148     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291712002759     Document Type: Article

References (48)

1. Amaral DG, Price JL (1984). Amygdalo-cortical projections in the monkey (Macaca fascicularis). Journal of Comparative Neurology 230, 465-496. (Pubitemid 15183874)
2. Anand A, Li Y, Wang Y, Wu J, Gao S, Bukhari L, Mathews VP, Kalnin A, Lowe MJ (2005a). Activity and connectivity of brain mood regulating circuit in depression : A functional magnetic resonance study. Biological Psychiatry 57, 1079-1088. (Pubitemid 40615768)
3. Anand A, Li Y, Wang Y, Wu J, Gao S, Bukhari L, Mathews VP, Kalnin A, Lowe MJ (2005b). Antidepressant effect on connectivity of the mood-regulating circuit : An FMRI study. Neuropsychopharmacology 30, 1334-1344. (Pubitemid 40848087)
4. Bajwa S, Bermpohl F, Rigonatti SP, Pascual-Leone A, Boggio PS, Fregni F (2008). Impaired interhemispheric interactions in patients with major depression. Journal of Nervous and Mental Disease 196, 671-677.
5. Chen CH, Suckling J, Ooi C, Fu CH, Williams SC, Walsh ND, Mitterschiffthaler MT, Pich EM, Bullmore E (2008). Functional coupling of the amygdala in depressed patients treated with antidepressant medication. Neuropsychopharmacology 33, 1909-1918. (Pubitemid 351832606)
6. Cordes D, Haughton VM, Arfanakis K, Carew JD, Turski PA, Moritz CH, Quigley MA, Meyerand ME (2001). Frequencies contributing to functional connectivity in the cerebral cortex in ' resting-state ' data. American Journal of Neuroradiology 22, 1326-1333. (Pubitemid 32734805)
7. Costafreda SG, Brammer MJ, David AS, Fu CH (2008). Predictors of amygdala activation during the processing of emotional stimuli : A meta-analysis of 385 PET and fMRI studies. Brain Research Reviews 58, 57-70.
8. Davidson RJ (2002). Anxiety and affective style : Role of prefrontal cortex and amygdala. Biological Psychiatry 51, 68-80. (Pubitemid 34093795)
9. Davidson RJ, Irwin W (1999). The functional neuroanatomy of emotion and affective style. Trends in Cognitive Sciences 3, 11-21. (Pubitemid 29045582)
10. Dougherty DD, Rauch SL, Deckersbach T, Marci C, Loh R, Shin LM, Alpert NM, Fischman AJ, Fava M (2004). Ventromedial prefrontal cortex and amygdala dysfunction during an anger induction positron emission tomography study in patients with major depressive disorder with anger attacks. Archives of General Psychiatry 61, 795-804. (Pubitemid 39031119)
11. Drevets WC, Price JL, Bardgett ME, Reich T, Todd RD, Raichle ME (2002). Glucose metabolism in the amygdala in depression : Relationship to diagnostic subtype and plasma cortisol levels. Pharmacology, Biochemistry and Behavior 71, 431-447. (Pubitemid 34126368)
12. Drevets WC, Price JL, Furey ML (2008). Brain structural and functional abnormalities in mood disorders : Implications for neurocircuitry models of depression. Brain Structure and Function 213, 93-118.
13. Fox MD, Zhang D, Snyder AZ, Raichle ME (2009). The global signal and observed anticorrelated resting state brain networks. Journal of Neurophysiology 101, 3270-3283.
14. Frodl T, Bokde AL, Scheuerecker J, Lisiecka D, Schoepf V, Hampel H, Moller HJ, Bruckmann H, Wiesmann M, Meisenzahl E (2010). Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression. Biological Psychiatry 67, 161-167.
15. Ghashghaei HT, Hilgetag CC, Barbas H (2007). Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala. NeuroImage 34, 905-923. (Pubitemid 46394469)
16. Greicius M (2008). Resting-state functional connectivity in neuropsychiatric disorders. Current Opinion in Neurology 21, 424-430.
17. Greicius MD, Flores BH, Menon V, Glover GH, Solvason HB, Kenna H, Reiss AL, Schatzberg AF (2007). Resting-state functional connectivity in major depression : Abnormally increased contributions from subgenual cingulate cortex and thalamus. Biological Psychiatry 62, 429-437. (Pubitemid 47284017)
18. Grimm S, Beck J, Schuepbach D, Hell D, Boesiger P, Bermpohl F, Niehaus L, Boeker H, Northoff G (2008). Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: An fMRI study in severe major depressive disorder. Biological Psychiatry 63, 369-376.
19. Hercher C, Turecki G, Mechawar N (2009). Through the looking glass : Examining neuroanatomical evidence for cellular alterations in major depression. Journal of Psychiatric Research 43, 947-961.
20. Horn DI, Yu C, Steiner J, Buchmann J, Kaufmann J, Osoba A, Eckert U, Zierhut KC, Schiltz K, He H, Biswal B, Bogerts B, Walter M (2010). Glutamatergic and resting-state functional connectivity correlates of severity in major depression-the role of pregenual anterior cingulate cortex and anterior insula. Frontiers in Systems Neuroscience 4, 33.
21. Jackson DC, Mueller CJ, Dolski I, Dalton KM, Nitschke JB, Urry HL, Rosenkranz MA, Ryff CD, Singer BH, Davidson RJ (2003). Now you feel it, now you don't : Frontal brain electrical asymmetry and individual differences in emotion regulation. Psychological Science 14, 612-617. (Pubitemid 37550865)
22. Johnstone T, van Reekum CM, Urry HL, Kalin NH, Davidson RJ (2007). Failure to regulate : Counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression. Journal of Neuroscience 27, 8877-8884. (Pubitemid 47292771)
23. Keedwell PA, Andrew C, Williams SC, Brammer MJ, Phillips ML (2005). A double dissociation of ventromedial prefrontal cortical responses to sad and happy stimuli in depressed and healthy individuals. Biological Psychiatry 58, 495-503. (Pubitemid 41393612)
24. Lebowitz BD, Pearson JL, Schneider LS, Reynolds 3rd CF, Alexopoulos GS, Bruce ML, Conwell Y, Katz IR, Meyers BS, Morrison MF, Mossey J, Niederehe G, Parmelee P (1997). Diagnosis and treatment of depression in late life. Consensus statement update. Journal of the American Medical Association 278, 1186-1190. (Pubitemid 27422429)
25. LeDoux JE (1992). Brain mechanisms of emotion and emotional learning. Current Opinion in Neurobiology 2, 191-197.
26. Lee BT, Seok JH, Lee BC, Cho SW, Yoon BJ, Lee KU, Chae JH, Choi IG, Ham BJ (2008). Neural correlates of affective processing in response to sad and angry facial stimuli in patients with major depressive disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 32, 778-785. (Pubitemid 351312379)
27. Liu Y, Hu D, Zhou Z, Shen H, Wang X (2008). fMRI noise reduction based on canonical correlation analysis and surrogate test. IEEE Journal of Selected Topics in Signal Processing 2, 870-878.
28. Liu Z, Xu C, Xu Y, Wang Y, Zhao B, Lv Y, Cao X, Zhang K, Du C (2010). Decreased regional homogeneity in insula and cerebellum : A resting-state fMRI study in patients with major depression and subjects at high risk for major depression. Psychiatry Research 182, 211-215.
29. Lowe MJ, Dzemidzic M, Lurito JT, Mathews VP, Phillips MD (2000). Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections. NeuroImage 12, 582-587.
30. MacQueen GM (2009). Magnetic resonance imaging and prediction of outcome in patients with major depressive disorder. Journal of Psychiatry and Neuroscience 34, 343-349.
31. Martinot JL, Hardy P, Feline A, Huret JD, Mazoyer B, Attar-Levy D, Pappata S, Syrota A (1990). Left prefrontal glucose hypometabolism in the depressed state : A confirmation. American Journal of Psychiatry 147, 1313-1317. (Pubitemid 20346268)
32. Mayberg HS, Liotti M, Brannan SK, McGinnis S, Mahurin RK, Jerabek PA, Silva JA, Tekell JL, Martin CC, Lancaster JL, Fox PT (1999). Reciprocal limbic-cortical function and negative mood: Converging PET findings in depression and normal sadness. American Journal of Psychiatry 156, 675-682. (Pubitemid 29220063)
33. Nitschke JB, Heller W, Etienne MA, Miller GA (2004). Prefrontal cortex activity differentiates processes affecting memory in depression. Biological Psychology 67, 125-143. (Pubitemid 38582076)
34. Ochsner KN, Gross JJ (2007). The neural architecture of emotion regulation. In Handbook of Emotion Regulation (ed. J. J. Gross), pp. 87-109. Guilford Press : New York.
35. Peng J, Liu J, Nie B, Li Y, Shan B, Wang G, Li K (2011). Cerebral and cerebellar gray matter reduction in firstepisode patients with major depressive disorder : A voxel-based morphometry study. European Journal of Radiology 80, 395-399.
36. Pessoa L (2008). On the relationship between emotion and cognition. Nature Reviews. Neuroscience 9, 148-158.
37. Pillai JJ, Friedman L, Stuve TA, Trinidad S, Jesberger JA, Lewin JS, Findling RL, Swales TP, Schulz SC (2002). Increased presence of white matter hyperintensities in adolescent patients with bipolar disorder. Psychiatry Research 114, 51-56. (Pubitemid 34178346)
38. Quirk GJ, Beer JS (2006). Prefrontal involvement in the regulation of emotion: Convergence of rat and human studies. Current Opinion in Neurobiology 16, 723-727. (Pubitemid 44791920)
39. Quirk GJ, Likhtik E, Pelletier JG, Pare D (2003). Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons. Journal of Neuroscience 23, 8800-8807. (Pubitemid 37176661)
40. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL (2001). A default mode of brain function. Proceedings of the National Academy of Sciences USA 98, 676-682. (Pubitemid 32105102)
41. Sackeim HA, Greenberg MS, Weiman AL, Gur RC, Hungerbuhler JP, Geschwind N (1982). Hemispheric asymmetry in the expression of positive and negative emotions. Neurologic evidence. Archives of Neurology 39, 210-218. (Pubitemid 12190280)
42. Sackeim HA, Prohovnik I, Moeller JR, Brown RP, Apter S, Prudic J, Devanand DP, Mukherjee S (1990). Regional cerebral blood flow in mood disorders. I. Comparison of major depressives and normal controls at rest. Archives of General Psychiatry 47, 60-70. (Pubitemid 20025547)
43. Sheline YI, Barch DM, Donnelly JM, Ollinger JM, Snyder AZ, Mintun MA (2001). Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment : An fMRI study. Biological Psychiatry 50, 651-658. (Pubitemid 33043767)
44. Siegle GJ, Thompson W, Carter CS, Steinhauer SR, Thase ME (2007). Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression : Related and independent features. Biological Psychiatry 61, 198-209. (Pubitemid 46072788)
45. Tomarken AJ, Davidson RJ, Wheeler RE, Doss RC (1992). Individual differences in anterior brain asymmetry and fundamental dimensions of emotion. Journal of Personality and Social Psychology 62, 676-687.
46. Urry HL, van Reekum CM, Johnstone T, Kalin NH, Thurow ME, Schaefer HS, Jackson CA, Frye CJ, Greischar LL, Alexander AL, Davidson RJ (2006). Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. Journal of Neuroscience 26, 4415-4425. (Pubitemid 44315400)
47. van Tol MJ, Demenescu LR, van der Wee NJ, Kortekaas R, Marjan MAN, Boer JA, Renken RJ, van Buchem MA, Zitman FG, Aleman A, Veltman DJ (2012). Functional magnetic resonance imaging correlates of emotional word encoding and recognition in depression and anxiety disorders. Biological Psychiatry 71, 593-602.
48. Veer IM, Beckmann CF, van Tol MJ, Ferrarini L, Milles J, Veltman DJ, Aleman A, van Buchem MA, van der Wee NJ, Rombouts SA (2010). Whole brain resting-state analysis reveals decreased functional connectivity in major depression. Frontiers in Systems Neuroscience 4, 41.