Octapod iron oxide nanoparticles as high-performance T 2 contrast agents for magnetic resonance imaging

Nature Communications

Volumn 4, Issue , 2013, Pages

  Zhao, Zhenghuan ^a   Zhou, Zijian ^a   Bao, Jianfeng ^b   Wang, Zhenyu ^b   Hu, Juan ^a   Chi, Xiaoqin ^b   Ni, Kaiyuan ^a   Wang, Ruifang ^b   Chen, Xiaoyuan ^c   Chen, Zhong ^b   Gao, Jinhao ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

^c NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; IRON OXIDE; OCTAPOD IRON OXIDE NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG;

CANCER; CHLORIDE; IRON OXIDE; MORPHOLOGY; NANOTECHNOLOGY; NUCLEAR MAGNETIC RESONANCE; TUMOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; IN VIVO STUDY; LIVER CANCER; LIVER INJURY; LOW DRUG DOSE; MORPHOLOGY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; SYNTHESIS;

EID: 84881420554     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3266     Document Type: Article

References (42)

1. Laurent, S. et al. Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem. Rev. 108, 2064-2110 (2008).
2. Tassa, C., Shaw, S. Y. & Weissleder, R. Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc. Chem. Res. 44, 842-852 (2011).
3. Corot, C., Robert, P., Idee, J. M. & Port, M. Recent advances in iron oxide nanocrystal technology for medical imaging. Adv. Drug Deliv. Rev. 58, 1471-1504 (2006).
4. Major, J. L. & Meade, T. J. Bioresponsive, cell-penetrating, and multimeric MR contrast agents. Acc. Chem. Res. 42, 893-903 (2009).
5. Weissleder, R. et al. Ultrasmall superparamagnetic iron oxide-characterization of a new class of contrast agnets for MR imaging. Radiology 175, 489-493 (1990).
6. Bulte, J. W. M. & Kraitchman, D. L. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed. 17, 484-499 (2004).
7. Harisinghani, M. G. et al. Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N. Engl. J. Med. 348, 2491-2495 (2003).
8. Gao, J. H., Gu, H. W. & Xu, B. Multifunctional magnetic nanoparticles: design, synthesis, and biomedical applications. Acc. Chem. Res. 42, 1097-1107 (2009).
9. Terreno, E., Castelli, D. D., Viale, A. & Aime, S. Challenges for molecular magnetic resonanceimaging. Chem. Rev. 110, 3019-3042 (2010).
10. 1 magnetic resonance imaging contrast agents. J. Am. Chem. Soc. 133, 12624-12631 (2011).
11. Lee, N. & Hyeon, T. Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents. Chem. Soc. Rev. 41, 2575-2589 (2012).
12. Lee, N. et al. Magnetosome-like ferrimagnetic iron oxide nanocubes for highly sensitive MRI of single cells and transplanted pancreatic islets. Proc. Natl Acad. Sci. USA 108, 2662-2667 (2011).
13. Ananta, J. S. et al. Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast. Nat. Nanotech. 5, 815-821 (2010).
14. Ghosh, D. et al. M13-templated magnetic nanoparticles for targeted in vivo imaging of prostate cancer. Nat. Nanotech. 7, 677-682 (2012).
15. Sun, S. H. & Zeng, H. Size-controlled synthesis of magnetite nanoparticies. J. Am. Chem. Soc. 124, 8204-8205 (2002).
16. Park, J. et al. Ultra-large-scale syntheses of monodisperse nanocrystals. Nat. Mater. 3, 891-895 (2004).
17. Lee, J.-H. et al. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nat. Med. 13, 95-99 (2007).
18. Jang, J.-t. et al. Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles. Angew. Chem. Int. Ed. 48, 1234-1238 (2009).
19. Yoo, D., Lee, J.-H., Shin, T.-H. & Cheon, J. Theranostic magnetic nanoparticles. Acc. Chem. Res. 44, 863-874 (2011).
20. 2 NMRD profiles of solutions of magnetic nanoparticles. Magn. Reson. Med. 34, 227-233 (1995).
21. Roch, A., Muller, R. N. & Gillis, P. Theory of proton relaxation induced by superparamagnetic particles. J. Chem. Phys. 110, 5403-5411 (1999).
22. 2-contrast agents. Adv. Healthcare Mater. 1, 502-512 (2012).
23. 2-shortening by strongly magnetized spheres: a partial refocusing model. Magn. Reson. Med. 47, 257-263 (2002).
24. 2 relaxivity. Nano Lett. 10, 4607-4613 (2010).
25. Tian, N., Zhou, Z. Y., Sun, S. G., Ding, Y. & Wang, Z. L. Synthesis of tetrahexahedral platinum nanocrystals with high-index facets and high electro-oxidation activity. Science 316, 732-735 (2007).
26. Lim, B., Xiong, Y. & Xia, Y. A water-based synthesis of octahedral, decahedral, and icosahedral Pd nanocrystals. Angew. Chem. Int. Ed. 46, 9279-9282 (2007).
27. Huang, X., Zhao, Z., Fan, J., Tan, Y. & Zheng, N. Amine-assisted synthesis of concave polyhedral platinum nanocrystals having [411] high-index facets. J. Am. Chem. Soc. 133, 4718-4721 (2011).
28. Zhang, J. et al. Concave cubic gold nanocrystals with high-index facets. J. Am. Chem. Soc. 132, 14012-14014 (2010).
29. Huang, X. et al. Freestanding palladium nanosheets with plasmonic and catalytic properties. Nat. Nanotech. 6, 28-32 (2011).
30. Yin, J. et al. Low-symmetry iron oxide nanocrystals bound by high-index facets. Angew. Chem. Int. Ed. 49, 6328-6332 (2010).
31. 4 nanostructures. Adv. Funct. Mater. 18, 1661-1667 (2008).
32. Hou, Y. L., Xu, Z. C. & Sun, S. H. Controlled synthesis and chemical conversions of FeO nanoparticles. Angew. Chem. Int. Ed. 46, 6329-6332 (2007).
33. Zabow, G., Dodd, S., Moreland, J. & Koretsky, A. Micro-engineered local field control for high-sensitivity multispectral MRI. Nature 453, 1058-1063 (2008).
34. Zabow, G., Dodd, S. J., Moreland, J. & Koretsky, A. P. The fabrication of uniform cylindrical nanoshells and their use as spectrally tunable MRI contrast agents. Nanotechnology 20, 385301 (2009).
35. Noh, S.-H. et al. Nanoscale magnetism control via surface and exchange anisotropy for optimized ferrimagnetic hysteresis. Nano Lett. 12, 3716-3721 (2012).
36. 2 dual-modal contrast agent. Adv. Mater. 24, 6223-6228 (2012).
37. Ai, H. et al. Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes. Adv. Mater. 17, 1949-1952 (2005).
38. Bruns, O. T. et al. Real-time magnetic resonance imaging and quantification of lipoprotein metabolism in vivo using nanocrystals. Nat. Nanotech. 4, 193-201 (2009).
39. Yoon, T.-J., Lee, H., Shao, H. & Weissleder, R. Highly magnetic core-shell nanoparticles with a unique magnetization mechanism. Angew. Chem. Int. Ed. 50, 4663-4666 (2011).
40. Huang, J. et al. Effects of nanoparticle size on cellular uptake and liver MRI with polyvinylpyrrolidone-coated iron oxide nanoparticles. ACS Nano 4, 7151-7160 (2010).
41. Ba-Ssalamah, A. et al. Clinical value of MRI liver-specific contrast agents: a tailored examination for a confident non-invasive diagnosis of focal liver lesions. Eur. Radiol. 19, 342-357 (2009).
42. Bjørnerud, A. & Johansson, L. The utility of superparamagnetic contrast agents in MRI: theoretical consideration and applications in the cardiovascular system. NMR Biomed. 17, 465-477 (2004).