Thiamine and fatigue in inflammatory bowel diseases: An open-label pilot study

Journal of Alternative and Complementary Medicine

Volumn 19, Issue 8, 2013, Pages 704-708

  Costantini, Antonio ^a,b   Pala, Maria Immacolata ^a  

^a Villa Immacolata ^*  (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; COCARBOXYLASE; MESALAZINE; SALAZOSULFAPYRIDINE; THIAMINE;

ADULT; ARTICLE; BODY WEIGHT; CHRONIC FATIGUE SYNDROME; CLINICAL ARTICLE; CLINICAL FEATURE; CROHN DISEASE; DRUG MEGADOSE; FATIGUE; FEMALE; GENERAL PRACTITIONER; GLUCOSE METABOLISM; HUMAN; OPEN STUDY; PASSIVE TRANSPORT; PILOT STUDY; PRIORITY JOURNAL; THIAMINE DEFICIENCY; ULCERATIVE COLITIS;

ADULT; FATIGUE; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; MIDDLE AGED; PILOT PROJECTS; THIAMINE; THIAMINE DEFICIENCY; TREATMENT OUTCOME;

EID: 84881401678     PISSN: 10755535     EISSN: 15577708     Source Type: Journal    
DOI: 10.1089/acm.2011.0840     Document Type: Article

References (17)

1. Fauci S, Braunwald E, Kasper DL, et al. Harrison's Principles of Internal Medicine 17th ed., New York: McGraw-Hill, 1999.
2. World Health Organization, United Nations High Commissioner for Refugees. Thiamine Deficiency and Its Prevention and Control in Major Emergencies. Report no: WHO/NHD/99.13, 1999.
3. Hardman JE, Limbird LE, Gilman AG. Goodman & Gil-man's The Pharmacological Basis of Therapeutics 10e. New York: McGraw-Hill, 2001.
4. Masur H. Neurologia. Ermes ed. Scale e Punteggi. Milan, 1999.
5. Kono S, Miyajima H, Yoshida K, et al. Mutation in a thia-mine-transporter gene and Wernicke's-like encephalopathy. N Engl J Med 2009;360:17921.
6. Lonsdale D. A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives. Evid Based Complement Alternat Med 2006;3:49-59.
7. Smithline HA, Donnino M, Greenblatt DJ. Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects. BMC Clinical Pharm 2012;12:4.
8. Magee E, Edmond L, Tasker S, et al. Association between diet and disease activity in ulcerative colitis patients using a novel method of data analysis. Nutrition Journal 2005;4:7.
9. Kitamura K, Yamaguchi T, Tanaka H, et al. TPN-induced fulminant beriberi: a report on our experience and a review of the literature. Surg Today 1996;26:769-76.
10. Shiozawa T, Shiota H, Shikata E, et al. Development of Wernicke's encephalopathy during the period of oral food intake after a subtotal colectomy for ulcerative colitis, Rinsho Shinkeigaku 1995;35:169-74.
11. Hahn JS, Berquist W, Alcorn DM, et al. Wernicke encepha-lopathy and beriberi during total parenteral nutrition attributable to multivitamin infusion shortage. Pediatrics 1998;101:E10.
12. Eggspühler AW, Bauerfeind P, Dorn T, Siegel AM. Wernicke encephalopathy-a severe neurological complication in a clinically inactive Crohn's disease. Eur Neurol 2003;50: 184-5.
13. Larnaout A, El-Euch G, Kchir N, et al. Wernicke's enceph-alopathy in a patient with Crohn's disease: a pathological study. J Neurol 2001;248:57-60.
14. Flabeau O, Foubert-Samier A, Meissner W, Tison F. Hearing and seeing: Unusual early signs of Wernicke encephalopa-thy. Neurology 2008;71:694.
15. Santhanam S, Rajamanickam S, Motamarry A, et al. Mitochondrial electron transport chain complex dysfunction in the colonic mucosa in ulcerative colitis. Inflamm Bowel Dis 2012;18:2158-68.
16. Davies SB, Joshua FF, Zagami AS. Wernicke's encephalop-athy in a non-alcoholic patient with a normal blood thiamine level. Med J Aust. 2011;194:483-4.
17. Singleton CK, Martin PR. Molecular mechanism of thiamine utilization. Curr Mol Med 2001;1:197-207.