Neurodegenerative disease: Defective mitochondrial dynamics in the hot seat - A therapeutic target common to many neurological disorders?

Nature Reviews Neurology

Volumn 9, Issue 8, 2013, Pages 417-

  Malpass, Katy ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DRP1 PROTEIN; LEUCINE RICH REPEAT KINASE 2; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RNA; PROTEIN P110; TRANSFER RNA; UNCLASSIFIED DRUG;

AUTOPHAGY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE MUTATION; HUMAN; HUNTINGTON CHOREA; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL ENCEPHALOMYOPATHY; MITOCHONDRIAL MYOPATHY; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; NOTE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVERSIBLE INFANTILE HEPATOPATHY; REVERSIBLE INFANTILE RESPIRATORY CHAIN DEFICIENCY; RNA TRANSLATION;

HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL ENCEPHALOMYOPATHIES; MITOCHONDRIAL PROTEINS; PROTEIN BIOSYNTHESIS; RNA, TRANSFER; TRNA METHYLTRANSFERASES;

EID: 84881374030     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2013.138     Document Type: Note

References (2)

1. Boczonadi, V. et al. Altered 2-thiouridylation impairs mitochondrial translation in reversible infantile respiratory chain deficiency. Hum. Mol. Genet. doi:10.1093/hmg/ddt309
2. Su, Y-C. & Qi, X. Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation. Hum. Mol. Genet. doi:10.1093/hmg/ddt301