Rates of false flagging due to statistical artifact in CMS evaluations of transplant programs: Results of a stochastic simulation

American Journal of Transplantation

Volumn 13, Issue 8, 2013, Pages 2044-2051

  Massie, A B ^a,b   Segev, D L ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Center for Medicare Medicaid Services; multiple outcomes; policy; transplant outcomes

Indexed keywords

ADULT; ARTICLE; CONDITIONS OF PARTICIPATION; HEALTH PROGRAM; HUMAN; MEDICAID; MEDICARE; MORTALITY; PRIORITY JOURNAL; RISK; SIMULATION; VALIDITY;

CENTER FOR MEDICARE/MEDICAID SERVICES; MULTIPLE OUTCOMES; POLICY; TRANSPLANT OUTCOMES;

ARTIFACTS; CENTERS FOR MEDICARE AND MEDICAID SERVICES (U.S.); COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; GRAFT SURVIVAL; HUMANS; MEDICAID; MEDICARE; ORGAN TRANSPLANTATION; PROGRAM EVALUATION; SURVIVAL RATE; TISSUE AND ORGAN PROCUREMENT; UNITED STATES;

EID: 84881333133     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12325     Document Type: Article

References (17)

1. 42 CFR § 482.82c 2007.
2. Dickinson DM, Shearon TH, O'Keefe J, et al. SRTR center-specific reporting tools: Posttransplant outcomes. Am J Transplant 2006; 6 (5 Pt 2): 1198-1211.
3. Abecassis MM, Burke R, Cosimi AB, et al. Transplant center regulations-A mixed blessing? An ASTS Council viewpoint. Am J Transplant 2008; 8: 2496-2502.
4. Weinhandl ED, Snyder JJ, Israni AK, Kasiske BL., Effect of comorbidity adjustment on CMS criteria for kidney transplant center performance. Am J Transplant 2009; 9: 506-516.
5. Howard RJ, Cornell DL, Schold JD., CMS oversight, OPOs and transplant centers and the law of unintended consequences. Clin Transplant 2009; 23: 778-783.
6. Schold JD, Srinivas TR, Howard RJ, Jamieson IR, Meier-Kriesche HU., The association of candidate mortality rates with kidney transplant outcomes and center performance evaluations. Transplantation 2008; 85: 1-6.
7. Benjamini Y, Hochberg Y., Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Stat Soc 1995; 57: 289-300.
8. Hochberg Y, Benjamini Y., More powerful procedures for multiple significance testing. Stat Med 1990; 9: 811-818.
9. Neuberger J, Madden S, Collett D., Review of methods for measuring and comparing center performance after organ transplantation. Liver Transplant 2010; 16: 1119-1128.
10. Dickinson D, Arrington C, Fant G, et al. SRTR program-specific reports on outcomes: A guide for the new reader. Am J Transplant 2008; 8 (4 pt 2): 1012-1026.
11. Ison MG, Hager J, Blumberg E, et al. Donor-derived disease transmission events in the United States: Data reviewed by the OPTN/UNOS Disease Transmission Advisory Committee. Am J Transplant 2009; 9: 1929-1935.
12. Ison MG, Holl JL, Ladner D., Preventable errors in organ transplantation: An emerging patient safety issue ? Am J Transplant 2012; 12: 2307-2312.
13. Gettleman JALK., Doctors Say Girl in Donor Mix-Up Has Permanent Brain Damage. New York Times February 22, 2003.
14. Feng S, Wolfe RA, Port FK., Frailty survival model analysis of the national deceased donor kidney transplant dataset using Poisson variance structures. J Am Stat Assoc 2005; 100: 728-735.
15. Abecassis MM, Burke R, Klintmalm GB, et al. American Society of Transplant Surgeons transplant center outcomes requirements-A threat to innovation. Am J Transplant 2009; 9: 1279-1286.
16. Port FK, Bragg-Gresham JL, Metzger RA, et al. Donor characteristics associated with reduced graft survival: An approach to expanding the pool of kidney donors. Transplantation 2002; 74: 1281-1286.
17. Hamilton TE., Improving organ transplantation in the United States-A regulatory perspective. Am J Transplant 2008; 8: 2503-2505.