-
1
-
-
74549114727
-
Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer
-
doi: 10.1111/j.1742-4658.2009.07448.x
-
Mitsudomi T, Yatabe Y, (2010) Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer. FEBS J 277: 301-308. doi:10.1111/j.1742-4658.2009.07448.x. PubMed: 19922469.
-
(2010)
FEBS J
, vol.277
, pp. 301-308
-
-
Mitsudomi, T.1
Yatabe, Y.2
-
2
-
-
79952232216
-
Global cancer statistics
-
doi: 10.3322/caac.20107
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, et al. (2011) Global cancer statistics. CA Cancer J Clin 61: 69-90. doi:10.3322/caac.20107. PubMed: 21296855.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
-
3
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
doi: 10.1038/nrc2088
-
Sharma SV, Bell DW, Settleman J, Haber DA, (2007) Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 7: 169-181. doi:10.1038/nrc2088. PubMed: 17318210.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 169-181
-
-
Sharma, S.V.1
Bell, D.W.2
Settleman, J.3
Haber, D.A.4
-
4
-
-
34347381855
-
EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy
-
doi: 10.1038/sj.onc.1210383
-
Irmer D, Funk JO, Blaukat A, (2007) EGFR kinase domain mutations- functional impact and relevance for lung cancer therapy. Oncogene 26: 5693-5701. doi:10.1038/sj.onc.1210383. PubMed: 17353898.
-
(2007)
Oncogene
, vol.26
, pp. 5693-5701
-
-
Irmer, D.1
Funk, J.O.2
Blaukat, A.3
-
5
-
-
77953133384
-
Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy
-
doi: 10.1016/j.febslet.2010.04.019
-
Pines G, Köstler WJ, Yarden Y, (2010) Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy. FEBS Lett 584: 2699-2706. doi:10.1016/j.febslet.2010.04.019. PubMed: 20388509.
-
(2010)
FEBS Lett
, vol.584
, pp. 2699-2706
-
-
Pines, G.1
Köstler, W.J.2
Yarden, Y.3
-
6
-
-
79952185499
-
Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating Epidermal Growth Factor Receptor mutation: implications for clinical practice and open issues
-
doi: 10.1016/j.lungcan.2010.12.009
-
Gridelli C, De Marinis F, Di Maio M, Cortinovis D, Cappuzzo F, et al. (2011) Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating Epidermal Growth Factor Receptor mutation: implications for clinical practice and open issues. Lung Cancer 72: 3-8. doi:10.1016/j.lungcan.2010.12.009. PubMed: 21216488.
-
(2011)
Lung Cancer
, vol.72
, pp. 3-8
-
-
Gridelli, C.1
De Marinis, F.2
Di Maio, M.3
Cortinovis, D.4
Cappuzzo, F.5
-
7
-
-
60749091249
-
Targeted cancer therapeutics
-
doi: 10.1158/0008-5472.CAN-08-3836, discussion 1267
-
Hait WN, Hambley TW, (2009) Targeted cancer therapeutics. Cancer Res 69: 1263-1267; discussion 1267 doi:10.1158/0008-5472.CAN-08-3836. PubMed: 19208830.
-
(2009)
Cancer Res
, vol.69
, pp. 1263-1267
-
-
Hait, W.N.1
Hambley, T.W.2
-
8
-
-
70350772288
-
Tyrosine kinase inhibitors - a review on pharmacology, metabolism and side effects
-
doi: 10.2174/138920009788897975
-
Hartmann JT, Haap M, Kopp HG, Lipp HP, (2009) Tyrosine kinase inhibitors- a review on pharmacology, metabolism and side effects. Curr Drug Metab 10: 470-481. doi:10.2174/138920009788897975. PubMed: 19689244.
-
(2009)
Curr Drug Metab
, vol.10
, pp. 470-481
-
-
Hartmann, J.T.1
Haap, M.2
Kopp, H.G.3
Lipp, H.P.4
-
9
-
-
77952295166
-
Allele-specific silencing by RNA interference
-
doi: 10.1007/978-1-60761-588-0_4
-
Hohjoh H, (2010) Allele-specific silencing by RNA interference. Methods Mol Biol 623: 67-79. doi:10.1007/978-1-60761-588-0_4. PubMed: 20217544.
-
(2010)
Methods Mol Biol
, vol.623
, pp. 67-79
-
-
Hohjoh, H.1
-
10
-
-
48249098892
-
Enhancement of allele discrimination by introduction of nucleotide mismatches into siRNA in allele-specific gene silencing by RNAi
-
doi: 10.1371/journal.pone.0002248
-
Ohnishi Y, Tamura Y, Yoshida M, Tokunaga K, Hohjoh H, (2008) Enhancement of allele discrimination by introduction of nucleotide mismatches into siRNA in allele-specific gene silencing by RNAi. PLOS ONE 3: e2248. doi:10.1371/journal.pone.0002248. PubMed: 18493311.
-
(2008)
PLOS ONE
, vol.3
-
-
Ohnishi, Y.1
Tamura, Y.2
Yoshida, M.3
Tokunaga, K.4
Hohjoh, H.5
-
11
-
-
33750331918
-
Assessment of allele-specific gene silencing by RNA interference with mutant and wild-type reporter alleles
-
19771217
-
Ohnishi Y, Tokunaga K, Kaneko K, Hohjoh H, (2006) Assessment of allele-specific gene silencing by RNA interference with mutant and wild-type reporter alleles. J RNAi Gene Silencing 2: 154-160. PubMed: 19771217.
-
(2006)
J RNAi Gene Silencing
, vol.2
, pp. 154-160
-
-
Ohnishi, Y.1
Tokunaga, K.2
Kaneko, K.3
Hohjoh, H.4
-
12
-
-
84863716164
-
Disease-causing allele-specific silencing against the ALK2 mutants, R206H and G356D, in fibrodysplasia ossificans progressiva
-
22130450
-
Takahashi M, Katagiri T, Furuya H, Hohjoh H, (2011) Disease-causing allele-specific silencing against the ALK2 mutants, R206H and G356D, in fibrodysplasia ossificans progressiva. Gene Ther, 19: 781-5. PubMed: 22130450.
-
(2011)
Gene Ther
, vol.19
, pp. 781-785
-
-
Takahashi, M.1
Katagiri, T.2
Furuya, H.3
Hohjoh, H.4
-
13
-
-
78650744437
-
Tailor-made RNAi knockdown against triplet repeat disease-causing alleles
-
doi: 10.1073/pnas.1012153107
-
Takahashi M, Watanabe S, Murata M, Furuya H, Kanazawa I, et al. (2010) Tailor-made RNAi knockdown against triplet repeat disease-causing alleles. Proc Natl Acad Sci U S A 107: 21731-21736. doi:10.1073/pnas.1012153107. PubMed: 21098280.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21731-21736
-
-
Takahashi, M.1
Watanabe, S.2
Murata, M.3
Furuya, H.4
Kanazawa, I.5
-
14
-
-
0031558797
-
Inhibition of gene expression from the human c-erbB gene promoter by a retroviral vector expressing anti-gene RNA
-
doi: 10.1006/bbrc.1997.7563
-
Okada T, Amanuma H, Okada Y, Obata M, Hayashi Y, et al. (1997) Inhibition of gene expression from the human c-erbB gene promoter by a retroviral vector expressing anti-gene RNA. Biochem Biophys Res Commun 240: 203-207. doi:10.1006/bbrc.1997.7563. PubMed: 9367910.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 203-207
-
-
Okada, T.1
Amanuma, H.2
Okada, Y.3
Obata, M.4
Hayashi, Y.5
-
15
-
-
6344269571
-
In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo
-
doi: 10.1002/jgm.490
-
Okada T, Caplen NJ, Ramsey WJ, Onodera M, Shimazaki K, et al. (2004) In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo. J Gene Med 6: 288-299. doi:10.1002/jgm.490. PubMed: 15026990.
-
(2004)
J Gene Med
, vol.6
, pp. 288-299
-
-
Okada, T.1
Caplen, N.J.2
Ramsey, W.J.3
Onodera, M.4
Shimazaki, K.5
-
16
-
-
67651011690
-
Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy
-
doi: 10.1002/jgm.1313
-
Uchibori R, Okada T, Ito T, Urabe M, Mizukami H, et al. (2009) Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy. J Gene Med 11: 373-381. doi:10.1002/jgm.1313. PubMed: 19274675.
-
(2009)
J Gene Med
, vol.11
, pp. 373-381
-
-
Uchibori, R.1
Okada, T.2
Ito, T.3
Urabe, M.4
Mizukami, H.5
-
17
-
-
2442668068
-
A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
-
doi: 10.1158/0008-5472.CAN-03-2682
-
Takei Y, Kadomatsu K, Yuzawa Y, Matsuo S, Muramatsu T, (2004) A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 64: 3365-3370. doi:10.1158/0008-5472.CAN-03-2682. PubMed: 15150085.
-
(2004)
Cancer Res
, vol.64
, pp. 3365-3370
-
-
Takei, Y.1
Kadomatsu, K.2
Yuzawa, Y.3
Matsuo, S.4
Muramatsu, T.5
-
18
-
-
24744464786
-
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
-
doi: 10.1073/pnas.0501753102
-
Takeshita F, Minakuchi Y, Nagahara S, Honma K, Sasaki H, et al. (2005) Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci U S A 102: 12177-12182. doi:10.1073/pnas.0501753102. PubMed: 16091473.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 12177-12182
-
-
Takeshita, F.1
Minakuchi, Y.2
Nagahara, S.3
Honma, K.4
Sasaki, H.5
-
19
-
-
3242733298
-
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
-
doi: 10.1093/nar/gnh093
-
Minakuchi Y, Takeshita F, Kosaka N, Sasaki H, Yamamoto Y, et al. (2004) Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 32: e109. doi:10.1093/nar/gnh093. PubMed: 15272050.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Minakuchi, Y.1
Takeshita, F.2
Kosaka, N.3
Sasaki, H.4
Yamamoto, Y.5
-
20
-
-
33845674968
-
Atelocollagen-mediated systemic DDS for nucleic acid medicines
-
doi: 10.1196/annals.1348.010
-
Hanai K, Takeshita F, Honma K, Nagahara S, Maeda M, et al. (2006) Atelocollagen-mediated systemic DDS for nucleic acid medicines. Ann N Y Acad Sci 1082: 9-17. doi:10.1196/annals.1348.010. PubMed: 17145919.
-
(2006)
Ann N Y Acad Sci
, vol.1082
, pp. 9-17
-
-
Hanai, K.1
Takeshita, F.2
Honma, K.3
Nagahara, S.4
Maeda, M.5
-
21
-
-
0034489914
-
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase
-
11156248
-
Sirotnak FM, Zakowski MF, Miller VA, Scher HI, Kris MG, (2000) Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res 6: 4885-4892. PubMed: 11156248.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4885-4892
-
-
Sirotnak, F.M.1
Zakowski, M.F.2
Miller, V.A.3
Scher, H.I.4
Kris, M.G.5
-
22
-
-
0037109014
-
ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
-
12384534
-
Wakeling AE, Guy SP, Woodburn JR, Ashton SE, Curry BJ, et al. (2002) ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 62: 5749-5754. PubMed: 12384534.
-
(2002)
Cancer Res
, vol.62
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
Ashton, S.E.4
Curry, B.J.5
-
23
-
-
4644274700
-
Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?
-
doi: 10.1016/j.molmed.2004.08.008
-
Gazdar AF, Shigematsu H, Herz J, Minna JD, (2004) Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends Mol Med 10: 481-486. doi:10.1016/j.molmed.2004.08.008. PubMed: 15464447.
-
(2004)
Trends Mol Med
, vol.10
, pp. 481-486
-
-
Gazdar, A.F.1
Shigematsu, H.2
Herz, J.3
Minna, J.D.4
-
24
-
-
37249003928
-
Oncogene addiction: setting the stage for molecularly targeted cancer therapy
-
doi: 10.1101/gad.1609907
-
Sharma SV, Settleman J, (2007) Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes Dev 21: 3214-3231. doi:10.1101/gad.1609907. PubMed: 18079171.
-
(2007)
Genes Dev
, vol.21
, pp. 3214-3231
-
-
Sharma, S.V.1
Settleman, J.2
|