Phosphate-induced rat vascular smooth muscle cell calcification and the implication of zinc deficiency in A7r5 cell viability

Preventive Nutrition and Food Science

Volumn 18, Issue 2, 2013, Pages 92-97

  Shin, Mee Young ^a   Kwun, In Sook ^a  

^a Andong National University   (South Korea)

Author keywords

Cell viability; Fetuin A; Phosphate; Rat vascular smooth muscle cell (VSMC); Zinc

Indexed keywords

EID: 84881300880     PISSN: 22871098     EISSN: 22878602     Source Type: Journal    
DOI: 10.3746/pnf.2013.18.2.092     Document Type: Article

References (18)

1. Shroff RC, Shanahan CM. 2007. The vascular biology of calcification. Semin Dial 20: 103-109.
2. Giachelli CM. 2009. The emerging role of phosphate in vascular calcification. Kidney Int 75: 890-897.
3. Speer MY, Giachelli CM. 2004. Regulation of cardiovascular calcification. Cardiovasc Pathol 13: 63-70.
4. Trion A, van der Laarse A. 2004. Vascular smooth muscle cells and calcification in atherosclerosis. Am Heart J 147: 808-814.
5. Jono S, McKee MD, Murry CE, Shioi A, Nishizawa Y, Mori K, Morii H, Giachelli CM. 2000. Phosphate regulation of vascular smooth muscle cell calcification. Circ Res 87: E10-E17.
6. Son BK, Akishita M, Iijima K, Eto M, Ouchi Y. 2008. Mechanism of pi-induced vascular calcification. J Atheroscler Thromb 15: 63-68.
7. Giachelli CM, Speer MY, Li X, Rajachar RM, Yang H. 2005. Regulation of vascular calcification: roles of phosphate and osteopontin. Circ Res 96: 717-722.
8. Alcantara EH, Shin MY, Feldmann J, Nixon GF, Beattie JH. Kwun IS. 2013. Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling. Atherosclerosis 228: 46-52.
9. Li X, Yang HY, Giachelli CM. 2006. Role of the sodiumdependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 98: 905-912.
10. Li X, Giachelli CM. 2007. Sodium-dependent phosphate cotransporters and vascular calcification. Curr Opin Nephrol Hypertens 16: 325-328.
11. Giachelli CM, Jono S, Shioi A, Nishizawa Y, Mori K, Morii H. 2001. Vascular calcification and inorganic phosphate. Am J Kidney Dis 38: S34-S37.
12. Giachelli CM. 2003. Vascular calcification: in vitro evidence for the role of inorganic phosphate. J Am Soc Nephrol 14: S300-S304.
13. Ou O, Allen-Redpath K, Urgast D, Gordon MJ, Campbell G, Feldmann J, Nixon GF, Mayer CD, Kwun IS, Beattie JH. 2013. Plasma zinc's alter ego is a low-molecular-weight humoral factor. FASEB J 27: doi: 10.1096/fj.13-228791
14. Allen-Redpath K, Ou O, Beattie JH, Kwun IS, Feldmann J, Nixon GF. 2013. Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries. Cardiovasc Res 99: doi: 10.1093/cvr/cvt114
15. Reynolds JL, Skepper JN, McNair R, Kasama T, Gupta K, Weissberg PL, Jahnen-Dechent W, Shanahan CM. 2005. Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. J Am Soc Nephrol 16: 2920-2930.
16. Chen NX, O'Neill KD, Chen X, Duan D, Wang E, Sturek MS, Edwards JM, Moe SM. 2007. Fetuin-A uptake in bovine vascular smooth muscle cells is calcium dependent and mediated by annexins. Am J Physiol Renal Physiol 292: F599-F606.
17. Jahnen-Dechent W, Heiss A, Schafer C, Ketteler M. 2011. Fetuin-A regulation of calcified matrix metabolism. Circ Res 108: 1494-1509.
18. Heiss A, DuChesne A, Denecke B, Grotzinger J, Yamamoto K, Renne T, Jahnen-Dechent W. 2003. Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. J Biol Chem 278: 13333-13341.