Toxicity features of high glucose on endothelial cell cycle and protection by Dan Gua-Fang in ECV-304 in high glucose medium

Chinese Journal of Integrative Medicine

Volumn 19, Issue 8, 2013, Pages 596-602

  Heng, Xian Pei ^a,b   Chen, Ke Ji ^b,c   Hong, Zhen Feng ^a   He, Wei Dong ^a   Chu, Ke Dan ^a   Lin, Jiu Mao ^c   Zheng, Hai Xia ^a   Yang, Liu Qing ^a   Huang, Su Ping ^a   Lan, Yuan Long ^a   Chen, Ling ^a   Guo, Fang ^a  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b XIYUAN HOSPITAL   (China)

^c People's Hospital Affiliated to Fujian Collage of Traditional Chinese Medicine   (China)

Author keywords

cell cycle; Chinese herbal compound; concurrent treatment of phlegm and blood stasis; Dan Gua Fang; diabetes mellitus; vascular lesion

Indexed keywords

CHINESE DRUG; DAN GUA FANG; GLUCOSE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DIABETES MELLITUS; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; LONG TERM CARE; OVARY CYCLE; OXIDATIVE STRESS; PRESCRIPTION; PRIORITY JOURNAL;

CELL CYCLE; CELLS, CULTURED; CULTURE MEDIA; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; ENDOTHELIAL CELLS; FLOW CYTOMETRY; GLUCOSE; HUMANS;

EID: 84881261755     PISSN: 16720415     EISSN: 19930402     Source Type: Journal    
DOI: 10.1007/s11655-011-0945-2     Document Type: Article

References (19)

1. Heng XP, Chen KJ, Hong ZF, He WD, Chu KD, Chen WL, et al. Glucose endothelial cytotoxicity and protection of Dan Gua-Fang, a Chinese herb prescription in huVEC in hyperglycemia medium. J Diabetes Complicat 2009;23:297-303.
2. Heng XP, Chen KJ. Intensive diabetic treatment and vasculopathy (II). Chin J Integr Tradit West Med (Chin) 2008;28:669-672.
3. Heng XP, Chen KJ. Intensive diabetic treatment and vasculopathy (I). Chin J Integr Tradit West Med (Chin) 2008;28:563-566.
4. Heng XP, Chen KJ, Hong ZF, He WD, Chu KD, Chen WL, et al. Research on ROS content variance of inner-ECV 304 in high glucose medium and influence of Dangua. Guangming Tradit Chin Med (Chin) 2008;23:551-555.
5. Bogdanski P, Pupek-Musialik D, Dytfeld J, Jagodzinski PP, Jablecka A, Kujawa A, et al. Influence of insulin therapy on expression of chemokine receptor CCR5 and selected inflammatory markers in patients with type 2 diabetes mellitus. Int J Clin Pharmacol Ther 2007;45:563-567.
6. Csiszar A, Ungvari ZI. Endothelial dysfunction and vascular inflammation in type II diabetes: interaction of AGE/RAGE and TNF-alpha signaling. Am J Physiol Heart Circ Physiol 2008;295:H475-H476.
7. Lorenzi M, Cagliero E, Toledo S. Glucose toxicity for human endothelial cells in culture. Delayed replication, disturbed cell cycle, and accelerated death. Diabetes 1985;34:621-627.
8. Heng XP, Chen KJ, Hong ZF, He WD, Chu KD, Chen WL, et al. Anticolchicine cytotoxicity enhanced by Dan Gua-Fang, a Chinese herb prescription in ECV304 in mediums. Chin J Integr Med 2011;17:126-133.
9. Ling HY, Hu B, Wang BX, Zu XY, Feng SD, Ou HS, et al. Effects of rosiglitazone on the proliferation of vascular smooth muscle cell induced by high glucose. Cardiovasc Drugs Ther 2008;22:453-460.
10. Cai J, Kehoe O, Smith GM, Hykin P, Boulton ME. The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy. Invest Ophthalmol Vis Sci 2008;49:2163-2171.
11. Lan CC, Liu IH, Fang AH, Wen CH, Wu CS. Hyperglycaemic conditions decrease cultured keratinocyte mobility: implications for impaired wound healing in patients with diabetes. Br J Dermatol 2008;159:1103-1115.
12. Asija A, Peterson SJ, Stec DE, Abraham NG. Targeting endothelial cells with heme oxygenase-1 gene using VE-cadherin promoter attenuates hyperglycemiamediated cell injury and apoptosis. Antioxid Redox Signal 2007;9:2065-2074.
13. Ejaz S, Chekarova I, Ejaz A, Sohail A, Lim CW. Importance of pericytes and mechanisms of pericyte loss during diabetes retinopathy. Diabetes Obes Metab 2008;10:53-63.
14. Nisoli E, Cozzi V, Carruba MO. Amino acids and mitochondrial biogenesis. Am J Cardiol 2008;101(11A):22E-25E.
15. Burnstock G. Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells. Pharmacol Rep 2008;60:12-20.
16. Keymel S, Kalka C, Rassaf T, Yeghiazarians Y, Kelm M, Heiss C. Impaired endothelial progenitor cell function predicts age-dependent carotid intimal thickening. Basic Res Cardiol 2008;103:582-586.
17. Onuta G, Westerweel PE, Zandvoort A, van Riezen M, Rozing J, Hillebrands JL, et al. Angiogenic sprouting from the aortic vascular wall is impaired in the BB rat model of autoimmune diabetes. Microvasc Res 2008;75:420-425.
18. Wu-Wong JR. Endothelial dysfunction and chronic kidney disease: treatment options. Curr Opin Investig Drugs 2008;9:970-982.
19. Heng XP. Strategies and methods for the treatment of diabetic neuropathy using integrative Chinese and Western medicine. Chin J Integr Med 2008;14:245-247.