Predictors of phase III slope of nitrogen single-breath washout in COPD

Respiratory Physiology and Neurobiology

Volumn 189, Issue 1, 2013, Pages 42-46

  Mikamo, Masashi ^a   Shirai, Toshihiro ^a   Mori, Kazutaka ^b   Shishido, Yuichiro ^a   Akita, Takefumi ^a   Morita, Satoru ^a   Asada, Kazuhiro ^a   Fujii, Masato ^a   Tsuchiya, Tomoyoshi ^c   Suda, Takafumi ^b  

^a SHIZUOKA GENERAL HOSPITAL   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHIZUOKA CITY SHIMIZU HOSPITAL   (Japan)

Author keywords

Delta N2; Forced oscillation technique; Pulmonary emphysema; Ventilation distribution inhomogeneity

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; MUSCARINIC RECEPTOR BLOCKING AGENT; THEOPHYLLINE;

ADULT; AGED; AIRWAY RESISTANCE; ARTICLE; BODY MASS; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DYSPNEA; EXPIRATORY RESERVE VOLUME; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HUMAN; INSPIRATORY CAPACITY; LUNG EMPHYSEMA; LUNG FUNCTION; LUNG FUNCTION TEST; LUNG MECHANICS; LUNG VENTILATION DISTRIBUTION; LUNG VOLUME; MAJOR CLINICAL STUDY; MALE; OSCILLATION; PREDICTOR VARIABLE; PRIORITY JOURNAL; RESIDUAL VOLUME; SINGLE BREATH NITROGEN TEST; SLOW VITAL CAPACITY; SMOKING; SPIROMETRY; SUSTAINED DRUG RELEASE; TOTAL LUNG CAPACITY;

DELTA N(2); FORCED OSCILLATION TECHNIQUE; PULMONARY EMPHYSEMA; VENTILATION DISTRIBUTION INHOMOGENEITY;

AGED; AGED, 80 AND OVER; BREATH TESTS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; NITROGEN; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; RESPIRATORY FUNCTION TESTS;

EID: 84881235723     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2013.06.018     Document Type: Article

References (19)

1. American Thoracic Society Standardization of spirometry, 1994 update. Am. J. Respir. Crit. Care Med. 1995, 152:1107-1136.
2. Bestall J.C., Paul E.A., Garrod R., Garnham R., Jones P.W., Wedzicha J.A. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax 1999, 54:581-586.
3. Contoli M., Bousquet J., Fabbri L.M., Magnussen H., Rabe K.F., Siafakas N.M., Hamid Q., Kraft M. The small airways and distal lung compartment in asthma and COPD: a time for reappraisal. Allergy 2010, 65:141-151.
4. Di Mango A.M., Lopes A.J., Jansen J.K., Melo P.L. Changes in respiratory mechanics with increasing degrees of airway obstruction in COPD: detection by forced oscillation technique. Respir. Med. 2006, 100:399-410.
5. Gennimata S.A., Palamidas A., Karakontaki F., Kosmas E.N., Koutsoukou A., Loukides S., Koulouris N.G. Pathophysiology of evolution of small airways disease to overt COPD. COPD 2010, 7:269-275.
6. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease 2013, www.goldcopd.org (Date last updated: February 20, 2013. Date last accessed: March 13, 2013).
7. Jones P.W., Harding G., Berry P., Wiklund I., Chen W.H., Leidy N.K. Development and first validation of the COPD assessment test. Eur. Respir. J. 2009, 34:648-654.
8. Kubota M., Shirai G., Nakamori T., Kokubo K., Masuda N., Kobayashi H. Low frequency oscillometry parameters in COPD patients are less variable during inspiration than during expiration. Respir. Physiol. Neurobiol. 2009, 166:73-79.
9. Kurosawa H., Ohishi J., Shimizu Y., Tasaku D., Kobayashi D., Masuda M., Kohzuki M., Maruta K., Hida W. Visualization of Frequency and Respiratory Cycle Dependency in the Lung Evaluated Using Impulse Oscillation 2009, www.ers-education.org/media/2009/eposters/1118.html (Date last updated: September 2009. Date last accessed: January 27, 2013).
10. Lapperre T.S., Willems L.N., Timens W., Rabe K.F., Hiemstra P.S., Postma D.S., Sterk P.J. Small airways dysfunction and neutrophilic inflammation in bronchial biopsies and BAL in COPD. Chest 2007, 131:53-59.
11. Mori K., Shirai T., Mikamo M., Shishido Y., Akita T., Morita S., Asada K., Fujii M., Suda T., Chida K. Colored 3-dimensional analyses of respiratory resistance and reactance in COPD and asthma. COPD 2011, 8:456-463.
12. Mori K., Shirai T., Mikamo M., Shishido Y., Akita T., Morita S., Asada K., Fujii M., Hozumi H., Suda T., Chida K. Respiratory mechanics measured by forced oscillation technique in combined pulmonary fibrosis and emphysema. Respir. Physiol. Neurobiol. 2013, 185:235-240.
13. Oostveen E., Macleod D., Lorino H., Farré R., Hantos Z., Desager K., Marchal F., on behalf of the ERS Task Force on Respiratory Impedance Measurements The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur. Respir. J. 2003, 22:1026-1041.
14. Robinson P.D., Goldman M.D., Gustafsson P.M. Inert gas washout: theoretical background and clinical utility in respiratory disease. Respiration 2009, 78:339-355.
15. Robinson P.D., Latzin P., Verbanck S., Hall G.L., Horsley A., Gappa M., Thamrin C., Arets H.G.M., Aurora P., Fuchs S.I., King G.G., Lum S., Macleod K., Paiva M., Pillow J.J., Ranganathan S., Ratjen F., Singer F., Sonnappa S., Stocks J., Subbarao P., Thompson B.R., Gustafsson P.M. Consensus statement for inert gas washout measurement using multiple and single breath tests. Eur. Respir. J. 2013, 41:507-522.
16. Timmins S.C., Diba C., Farrow C.E., Schoeffel R.E., Berend N., Salome C.M., King G.G. The relationship between airflow obstruction, emphysema extent, and small airways function in COPD. Chest 2012, 142:312-319.
17. van den Berge M., ten Hacken N.H., Cohen J., Douma W.R., Postma D.S. Small airway disease in asthma and COPD: clinical implications. Chest 2011, 139:412-423.
18. Verbanck S. Physiological measurement of the small airways. Respiration 2012, 84:177-188.
19. Wanger J., Clausen J.L., Coates A., Pedersen O.F., Brusasco V., Burgos F., Casaburi R., Crapo R., Enright P., van der Grinten C.P., Gustafsson P., Hankinson J., Jensen R., Johnson D., Macintyre N., McKay R., Miller M.R., Navajas D., Pellegrino R., Viegi G. Standardisation of the measurement of lung volumes. Eur. Respir. J. 2005, 26:511-522.