Crystal structure of a human IκB Kinase β asymmetric dimer

Journal of Biological Chemistry

Volumn 288, Issue 31, 2013, Pages 22758-22767

  Liu, Shenping ^a   Misquitta, Yohann R ^a,b   Olland, Andrea ^a,c   Johnson, Mark A ^a   Kelleher, Kerry S ^a   Kriz, Ron ^a   Lin, Laura L ^a   Stahl, Mark ^a   Mosyak, Lidia ^a  

^a PFIZER INC   (United States)

^b Adimab LLC   (United States)

^c UNITED BIOSOURCE CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ASYMMETRIC DIMERS; HIGH-RESOLUTION STRUCTURES; INHIBITOR DESIGN; KEY REGULATORS; SIGNALING PATHWAYS; STRUCTURAL BASIS;

PHOSPHORYLATION;

ENZYMES;

AMINO TERMINAL TELOPEPTIDE; CARBOXY TERMINAL TELOPEPTIDE; DIMER; I KAPPA B KINASE BETA; K 252A; UBIQUITIN;

ARTICLE; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; XENOPUS LAEVIS;

CRYSTALLOGRAPHY; ENZYME MECHANISMS; NF-KAPPA B (NF-KB); SIGNALING; THREONINE-SERINE PROTEIN KINASE;

CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; I-KAPPA B KINASE; LIGANDS; MODELS, MOLECULAR; PHOSPHORYLATION;

EID: 84881225453     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.482596     Document Type: Article

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