Combatting Substandard and Falsified Medicines: A View from Rwanda

PLoS Medicine

Volumn 10, Issue 7, 2013, Pages

  Binagwaho, Agnes ^a,b,c   Bate, Roger ^d   Gasana, Michel ^e   Karema, Corine ^e   Mucyo, Yves ^e   Mwesigye, John Patrick ^a   Biziyaremye, Floribert ^e   Nutt, Cameron T ^f   Wagner, Claire M ^g   Jensen, Paul ^h   Attaran, Amir ⁱ  

^a Ministry of Health of Rwanda   (Rwanda)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d AMERICAN ENTERPRISE INSTITUTE   (United States)

^e RWANDA BIOMEDICAL CENTER   (Rwanda)

^f DARTMOUTH INSTITUTE FOR HEALTH POLICY AND CLINICAL PRACTICE   (United States)

^g Global Health Delivery Partnership   (United States)

^h Pivit LLC HQ   (United States)

ⁱ UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COUNTERFEIT DRUG; ISONIAZID; RIFAMPICIN;

ARTICLE; CRIMINAL LAW; DRUG QUALITY; DRUG SURVEILLANCE PROGRAM; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; GOOD MANUFACTURING PRACTICE; HEALTH CENTER; HUMAN; MALARIA; MEDICINE; MORTALITY; MULTIDRUG RESISTANT TUBERCULOSIS; ORGANIZATION AND MANAGEMENT; PRACTICE GUIDELINE; TUBERCULOSIS; TUBERCULOSIS CONTROL;

EID: 84881220400     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001476     Document Type: Article

References (14)

1. Institute of Medicine (2013) Countering the problem of falsified and substandard drugs. Washington (District of Columbia): The National Academies Press. Available: http://www.iom.edu/Reports/2013/Countering-the-Problem-of-Falsified-and-Substandard-Drugs.aspx. Accessed 17 February 2013.
2. Attaran A, Barry D, Basheer S, Bate R, Benton D, et al. (2012) How to achieve international action on falsified and substandard medicines. BMJ 345: e7381 Available: http://www.bmj.com/content/345/bmj.e7381. Accessed 19 February 2013.
3. Jack A, (2012) Faking it. BMJ 345: e7836.
4. Bate R, Jensen P, Hess K, Mooney L, Milligan J, (2013) Substandard and falsified anti-tuberculosis drugs: a preliminary field analysis. Int J Tuberc Lung Dis 17: 308-311 Available: http://www.aei.org/files/2013/02/05/-substandard-and-falsified-antituberculosis-drugs-a-preliminary-field-analysis_142125219328.pdf. Accessed 15 February 2013.
5. Singh S, Bhutani H, Mariappan TT, (2006) Quality problems of anti-tuberculosis fixed-dose combinations (FDCs): a way forward. Indian J Tuberc 53: 201-205.
6. Laserson KF, Kenyon AS, Kenyon TA, Layloff T, Binkin NJ, (2001) Substandard tuberculosis drugs on the global market and their simple detection. Int J Tuberc Lung Dis 5: 448-454.
7. Bate R, Coticelli P, Tren R, Attaran A, (2008) Antimalarial drug quality in the most severely malarious parts of Africa-a six country study. PLoS ONE 3: e2132 doi:10.1371/journal.pone.0002132.
8. Bate R, Mooney L, Hess K, Milligan J, Attaran A, (2012) Anti-infective medicine quality: analysis of basic product quality by approval status and country of manufacture. Res Rep Trop Med 3: 57-61 Available: http://papers.ssrn.com/sol3/papers.cfm?abstract_id=2138438. Accessed 20 February 2013.
9. Bate R, Hess K, (2012) The role of pre-shipment batch testing in ensuring good medicine quality. Malaria World J 3: 11 Available: http://www.aei.org/files/2012/12/05/-bate-the-role-of-preshipment-batch-testing-in-ensuring-good-medicine-quality_12150071370.pdf. Accessed 18 February 2013.
10. Ministry of Health of Rwanda (2011) Guidelines for pharmacovigilance and medicine information system in Rwanda. Kigali: Ministry of Health of Rwanda. Available: http://spssms.msh.org/products/Rwanda_Pharmacovigilance%20Guidelines%20last%20draft%20version%2014%20June%202011.pdf. Accessed 20 February 2013.
11. Farmer PE, Nutt CT, Wagner CM, Sekabaraga C, Nuthulaganti T, et al. (2013) Reduced premature mortality in Rwanda: lessons from success. BMJ 346: f65 Available: http://www.bmj.com/content/346/bmj.f65. Accessed 17 February 2013.
12. World Health Organization (2012) Global tuberculosis report 2012. Available: http://www.who.int/tb/publications/global_report/en/. Accessed 24 May 2013.
13. Binagwaho A, Gasana M, Mucyo Y, Wagner CM, Nutt CT, (2013) Resistant TB: use the tools available. Nature 494: 176 Available: http://www.nature.com/nature/journal/v494/n7436/full/494176a.html. Accessed 20 February 2013.
14. Binagwaho A, Bate R, (2013) Substandard drugs and the fight against TB: the challenge and the opportunity. Health Affairs Blog Available: http://healthaffairs.org/blog/2013/04/15/substandard-drugs-and-the-fight-against-tb-the-challenge-and-the-opportunity/. Accessed 15 April 2013.