Hwanggeumchal sorghum extract enhances BMP7 and GH signaling through the activation of Jak2/STAT5B in MC3T3-E1 osteoblastic cells

Molecular Medicine Reports

Volumn 8, Issue 3, 2013, Pages 891-896

  Joung, Youn Hee ^a   Lim, Eun Joung ^a   Darvin, Pramod ^a   Jang, Ju Woong ^b   Park, Kyung Do ^c   Lee, Hak Kyo ^c   Kim, Heui Soo ^d   Cho, Byung Wook ^d   Park, Taekyu ^e   Chung, Sumi ^f   Park, Jong Hwan ^g   Yang, Young Mok ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Korea Bone Bank Co Ltd   (South Korea)

^c Hankyong National University   (South Korea)

^d Pusan National University   (South Korea)

^e Konkuk University   (South Korea)

^f UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^g Dongguk University   (South Korea)

Author keywords

Bone morphogenetic protein 7; Growth hormone; Growth hormone receptor; Hwanggeumchal sorghum extracts; Insulin like growth factor 1 receptor; Janus kinase 2; Osteoblasts; Signal transducers and activators of transcription 5B

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR; HWANGGEUMCHAL SORGHUM EXTRACT; JANUS KINASE 2; MESSENGER RNA; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; OSTEOGENIC PROTEIN 1; PLANT EXTRACT; SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR; STAT5B PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE GROWTH; CONTROLLED STUDY; DRUG ANTAGONISM; ENZYME ACTIVATION; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SORGHUM;

ANIMALS; BONE MORPHOGENETIC PROTEIN 7; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; GENE EXPRESSION; GROWTH HORMONE; JANUS KINASE 2; MICE; OSTEOBLASTS; PLANT EXTRACTS; RECEPTOR, IGF TYPE 1; RECEPTORS, SOMATOTROPIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SORGHUM; STAT5 TRANSCRIPTION FACTOR; TYRPHOSTINS;

EID: 84881193049     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1593     Document Type: Article

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