The role of β-amyloid in Alzheimer's disease-related neurodegeneration

Journal of Neuroscience

Volumn 33, Issue 32, 2013, Pages 12910-12911

  Goldsworthy, Mitchell R ^a   Vallence, Ann Maree ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; FLUORODEOXYGLUCOSE F 18;

ALZHEIMER DISEASE; BRAIN INJURY; COGNITIVE DEFECT; DEMENTIA; DISEASE COURSE; EXECUTIVE FUNCTION; HUMAN; MEMORY; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROLOGIC DISEASE; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RISK FACTOR; SENILE PLAQUE;

ALZHEIMER DISEASE; AMYLOID; BIOLOGICAL MARKERS; COGNITION DISORDERS; FEMALE; HUMANS; MALE;

EID: 84881189463     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2252-13.2013     Document Type: Note

References (12)

1. Braak H, Del Tredici K (2011) The pathological process underlying Alzheimer's disease in individuals under thirty. Acta neuropathologica 121:171-181. CrossRef Medline
2. De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL (2008) Alzheimer's diseasetype neuronal tau hyperphosphorylation induced by a beta oligomers. Neurobiol Aging 29:1334-1347. CrossRef Medline
3. Fukumoto H, Tokuda T, Kasai T, Ishigami N, Hidaka H, Kondo M, Allsop D, Nakagawa M (2010) High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients. FASEB J 24:2716-2726. CrossRef Medline
4. Jack CR Jr, Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, Petersen RC, Trojanowski JQ (2010) Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 9:119-128. CrossRef Medline
5. Jack CR Jr, Knopman DS, Weigand SD, Wiste HJ, Vemuri P, Lowe V, Kantarci K, Gunter JL, Senjem ML, Ivnik RJ, Roberts RO, Rocca WA, Boeve BF, Petersen RC (2012) An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease. Ann Neurol 71:765-775. CrossRef Medline
6. Jack CR Jr, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, Shaw LM, Vemuri P, Wiste HJ, Weigand SD, Lesnick TG, Pankratz VS, Donohue MC, Trojanowski JQ (2013) Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol 12:207-216. CrossRef Medline
7. Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergström M, Savitcheva I, Huang GF, Estrada S, Ausén B, Debnath ML, Barletta J, Price JC, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA, Långström B (2004) Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol 55:306-319. CrossRef Medline
8. Prince M, Jackson J, eds (2009) Alzheimer's disease international world alzheimer report 2009. London: Alzheimer's Disease International.
9. Santos AN, Ewers M, Minthon L, Simm A, Silber RE, Blennow K, Prvulovic D, Hansson O, Hampel H (2012) Amyloid-beta oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease. J Alzheimers Dis 29:171-176. CrossRef Medline
10. Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR Jr, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7:280-292. CrossRef Medline
11. Walsh DM, Selkoe DJ (2007) A beta oligomers- a decade of discovery. J Neurochem 101:1172-1184. CrossRef Medline
12. Wirth M, Madison CM, Rabinovici GD, Oh H, Landau SM, Jagust WJ (2013) Alzheimer's disease neurodegenerative biomarkers are associated with decreased cognitive function but not beta-amyloid in cognitively normal older individuals. J Neurosci 33:5553-5563. CrossRef Medline