Differential binding modes of anti-cancer, anti-HIV drugs belonging to isatin family with a model transport protein: A joint refinement from spectroscopic and molecular modeling approaches

Journal of Photochemistry and Photobiology B: Biology

Volumn 127, Issue , 2013, Pages 18-27

  Ray, Debarati ^a   Paul, Bijan K ^a,b   Guchhait, Nikhil ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

AutoDock simulation; BSA; CD; Drug isatin and methyl isatin; Drug protein interaction; Fluorescence; Protein

Indexed keywords

1 METHYLISATIN; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; BOVINE SERUM ALBUMIN; ISATIN; ISATIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; AUTODOCK BASED BLIND DOCKING SIMULATION; BINDING AFFINITY; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONSTANT WAVELENGTH SYNCHRONOUS FLUORESCENCE SPECTROSCOPY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG PROTEIN BINDING; ENZYME ACTIVITY; EXCITATION EMISSION MATRIX FLUORESCENCE SPECTROSCOPY; FLUORESCENCE SPECTROSCOPY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIMULATION; STEADY STATE; STOPPED FLOW FLUORESCENCE TECHNIQUE; THERMODYNAMICS; TIME RESOLVED FLUORESCENCE SPECTROSCOPY;

BOVINAE;

AUTODOCK SIMULATION; CD; DRUG ISATIN AND METHYL ISATIN; DRUG PROTEIN INTERACTION; FLUORESCENCE; PROTEIN BSA;

ANIMALS; ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; CATTLE; ESTERASES; INDOLES; ISATIN; KINETICS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SERUM ALBUMIN, BOVINE; SPECTRUM ANALYSIS; THERMODYNAMICS;

EID: 84881011508     PISSN: 10111344     EISSN: 18732682     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2013.06.016     Document Type: Article

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