Imaging techniques for visualizing and phenotyping congenital heart defects in murine models

Birth Defects Research Part C - Embryo Today: Reviews

Volumn 99, Issue 2, 2013, Pages 93-105

  Liu, Xiaoqin ^a   Tobita, Kimimasa ^a   Francis, Richard J B ^a   Lo, Cecilia W ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Congenital heart defect; Imaging

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; BIOMICROSCOPY; BLOOD FLOW VELOCITY; CONGENITAL HEART MALFORMATION; DIAGNOSTIC IMAGING; DIAGNOSTIC PROCEDURE; ECHOCARDIOGRAPHY; EPISCOPIC FLUORESCENCE IMAGE CAPTURE; GOLD STANDARD; HEART FUNCTION; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; IMAGE ANALYSIS; MEASUREMENT; MICRO-COMPUTED TOMOGRAPHY; MICROMAGNETIC RESONANCE IMAGING; MOUSE; MUTAGENESIS; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REVIEW;

EID: 84881004101     PISSN: 1542975X     EISSN: 15429768     Source Type: Journal    
DOI: 10.1002/bdrc.21037     Document Type: Review

References (36)

1. Berrios-Otero CA, Wadghiri YZ, Nieman BJ, Joyner AL, Turnbull DH. 2009. Three-dimensional micro-MRI analysis of cerebral artery development in mouse embryos. Magn Reson Med 62:1431-1439.
2. Cheng KC, Xin X, Clark DP, La Riviere P. 2011. Whole-animal imaging, gene function, and the Zebrafish Phenome Project. Curr Opin Genet Dev 21:620-629.
3. Cleary JO, Price AN, Thomas DL, Scambler PJ, Kyriakopoulou V, McCue K, Schneider JE, Ordidge RJ, Lythgoe MF. 2009. Cardiac phenotyping in ex vivo murine embryos using microMRI. NMR Biomed 22:857-866.
4. Degenhardt K, Wright AC, Horng D, Padmanabhan A, Epstein JA. 2010. Rapid 3D phenotyping of cardiovascular development in mouse embryos by micro-CT with iodine staining. Circ Cardiovasc Imaging 3:314-322.
5. Feuerstein M, Heibel H, Gardiazabal J, Navab N, Groher M. 2011. Reconstruction of 3-D histology images by simultaneous deformable registration. Med Image Comput Comput Assist Interv 14 (Part 2):582-589.
6. Frank LH, Yu Q, Francis R, Tian X, Samtani R, Sahn DJ, Leatherbury L, Lo CW. 2010. Ventricular rotation is independent of cardiac looping: a study in mice with situs inversus totalis using speckle-tracking echocardiography. J Am Soc Echocardiogr 23:315-323.
7. French J, Gingles N, Stewart J, Woodhouse N. 2010. Use of magnetic resonance imaging (MRI) and micro-computed tomography (micro-CT) in the morphological examination of rat and rabbit fetuses from embryo-fetal development studies. Reprod Toxicol 30:292-300.
8. Gregg CL, Butcher JT. 2012. Quantitative in vivo imaging of embryonic development: opportunities and challenges. Differ Res Biol Diversity 84:149-162.
9. Hiraiwa N, Ishimoto M, Yasue H. 2013. Examination of the mouse embryo by micro-CT. Exp Anim Jpn Assoc Lab Anim Sci 62:57-61.
10. Hogers B, van der Weerd L, Olofsen H, van der Graaf LM, DeRuiter MC, Gittenberger-de Groot AC, Poelmann RE. 2009. Non-invasive tracking of avian development in vivo by MRI. NMR Biomed 22:365-373.
11. Moran CM, Thomson AJ, Rog-Zielinska E, Gray GA. 2013. High-resolution echocardiography in the assessment of cardiac physiology and disease in preclinical models. Exp Physiol 98:629-644.
12. Nieman BJ, Turnbull DH. 2010. Ultrasound and magnetic resonance microimaging of mouse development. Methods Enzymol 476:379-400.
13. Pallares P, Fernandez-Valle ME, Gonzalez-Bulnes A. 2009. In vivo virtual histology of mouse embryogenesis by ultrasound biomicroscopy and magnetic resonance imaging. Reprod Fertil Dev 21:283-292.
14. Parnell SE, O'Leary-Moore SK, Godin EA, Dehart DB, Johnson BW, Allan Johnson G, Styner MA, Sulik KK. 2009. Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. Alcohol Clin Exp Res 33:1001-1011.
15. Peng Y, Popovic ZB, Sopko N, Drinko J, Zhang Z, Thomas JD, Penn MS. 2009. Speckle tracking echocardiography in the assessment of mouse models of cardiac dysfunction. Am J Physiol Heart Circ Physiol 297:H811-H820.
16. Petiet AE, Kaufman MH, Goddeeris MM, Brandenburg J, Elmore SA, Johnson GA. 2008. High-resolution magnetic resonance histology of the embryonic and neonatal mouse: a 4D atlas and morphologic database. Proc Natl Acad Sci USA 105:12331-12336.
17. Phoon CK. 2006. Imaging tools for the developmental biologist: ultrasound biomicroscopy of mouse embryonic development. Pediatr Res 60:14-21.
18. Phoon CK, Turnbull DH. 2003. Ultrasound biomicroscopy-Doppler in mouse cardiovascular development. Physiol Genom 14:3-15.
19. Ritman EL. 2011. Current status of developments and applications of micro-CT. Annu Rev Biomed Eng 13:531-552.
20. Rosenthal J, Mangal V, Walker D, Bennett M, Mohun TJ, Lo CW. 2004. Rapid high resolution three dimensional reconstruction of embryos with episcopic fluorescence image capture. Birth Defects Res C Embryo Today 72:213-223.
21. Rosset A, Spadola L, Ratib O. 2004. OsiriX: an open-source software for navigating in multidimensional DICOM images. J Digit Imaging 17:205-216.
22. Saalfeld S, Fetter R, Cardona A, Tomancak P. 2012. Elastic volume reconstruction from series of ultra-thin microscopy sections. Nat Methods 9:717-720.
23. Schambach SJ, Bag S, Schilling L, Groden C, Brockmann MA. 2010. Application of micro-CT in small animal imaging. Methods 50:2-13.
24. Scherrer-Crosbie M, Kurtz B. 2010. Ventricular remodeling and function: insights using murine echocardiography. J Mol Cell Cardiol 48:512-517.
25. Shen Y, Leatherbury L, Rosenthal J, Yu Q, Pappas MA, Wessels A, Lucas J, Siegfried B, Chatterjee B, Svenson K, Lo CW. 2005. Cardiovascular phenotyping of fetal mice by noninvasive high-frequency ultrasound facilitates recovery of ENU-induced mutations causing congenital cardiac and extracardiac defects. Physiol Genom 24:23-36.
26. Spurney CF, Lo CW, Leatherbury L. 2006. Fetal mouse imaging using echocardiography: a review of current technology. Echocardiography 23:891-899.
27. Tan SY, Rosenthal J, Zhao XQ, Francis RJ, Chatterjee B, Sabol SL, Linask KL, Bracero L, Connelly PS, Daniels MP, Yu Q, Omran H, Leatherbury L, Lo CW. 2007. Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia. J Clin Invest 117:3742-3752.
28. Tobita K, Liu X, Lo CW. 2010. Imaging modalities to assess structural birth defects in mutant mouse models. Birth Defects Res C Embryo Today Rev 90:176-184.
29. Weninger WJ, Meng S, Streicher J, Muller GB. 1998. A new episcopic method for rapid 3-D reconstruction: applications in anatomy and embryology. Anat Embryol (Berl) 197:341-348.
30. Weninger WJ, Mohun T. 2002. Phenotyping transgenic embryos: a rapid 3-D screening method based on episcopic fluorescence image capturing. Nat Genet 30:59-65.
31. Wiesmann F, Ruff J, Hiller KH, Rommel E, Haase A, Neubauer S. 2000. Developmental changes of cardiac function and mass assessed with MRI in neonatal, juvenile, and adult mice. Am J Physiol Heart Circ Physiol 278:H652-H657.
32. Yamada S, Samtani RR, Lee ES, Lockett E, Uwabe C, Shiota K, Anderson SA, Lo CW. 2010. Developmental atlas of the early first trimester human embryo. Dev Dyn 239:1585-1595.
33. Yelbuz TM, Wessel A, Kirby ML. 2004. Studies on morphogenesis and visualization of the early embryonic heart with regard to the development of conotruncal heart defects. Z Kardiol 93:583-594.
34. Yu Q, Leatherbury L, Tian X, Lo CW. 2008. Cardiovascular assessment of fetal mice by in utero echocardiography. Ultrasound Med Biol 34:741-752.
35. Yu Q, Shen Y, Chatterjee B, Siegfried BH, Leatherbury L, Rosenthal J, Lucas JF, Wessels A, Spurney CF, Wu YJ, Kirby ML, Svenson K, Lo CW. 2004. ENU induced mutations causing congenital cardiovascular anomalies. Development 131:6211-6223.
36. Zouagui T, Chereul E, Janier M, Odet C. 2010. 3D MRI heart segmentation of mouse embryos. Comput Biol Med 40:64-74.