Chronic ethanol (EtOH) consumption differentially alters gray and white matter EtOH methyl 1H magnetic resonance intensity in the primate brain

Alcoholism: Clinical and Experimental Research

Volumn 37, Issue 8, 2013, Pages 1325-1332

  Kroenke, Christopher D ^a,b,c   Flory, Graham S ^a   Park, Byung ^b   Shaw, Jessica ^a   Rau, Andrew R ^a   Grant, Kathleen A ^a,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Ethanol; Gray Matter; Magnetic Resonance Spectroscopy; Nonhuman Primate; Self Administration

Indexed keywords

ALCOHOL;

AGE; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL STUDY; GRAY MATTER; IN VIVO STUDY; LONG TERM EXPOSURE; LONGITUDINAL STUDY; MALE; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; WHITE MATTER;

ETHANOL; GRAY MATTER; MAGNETIC RESONANCE SPECTROSCOPY; NONHUMAN PRIMATE; SELF-ADMINISTRATION;

ALCOHOL DRINKING; ALCOHOL-RELATED DISORDERS; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHRONIC DISEASE; ETHANOL; HYDROGEN; MACACA MULATTA; MAGNETIC RESONANCE SPECTROSCOPY; MALE;

EID: 84880981262     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12097     Document Type: Article

References (48)

1. Adalsteinsson E, Sullivan EV, Mayer D, Pfefferbaum A (2006) In vivo quantification of ethanol kinetics in rat brain. Neuropsychopharmacology 31:2683-2691.
2. Andersen AH, Zhang Z, Zhang M, Gash DM, Avison MJ (1999) Age-associated changes in rhesus CNS composition identified by MRI. Brain Res 829:90-98.
3. Bendszus M, Weijers HG, Wiesbeck G, Warmuth-Metz M, Bartsch AJ, Engels S, Boning J, Solymosi L (2001) Sequential MR imaging and proton MR spectroscopy in patients who underwent recent detoxification for chronic alcoholism: correlation with clinical and neuropsychological data. AJNR Am J Neuroradiol 22:1926-1932.
4. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B 57:289-300.
5. Chiu TM, Mendelson JH, Sholar MB, Mutschler NH, Wines JD, Hesselbrock VM, Mello NK (2004) Brain alcohol detectability in human subjects with and without a paternal history of alcoholism. J Stud Alcohol 65:16-21.
6. Chiu TM, Mendelson JH, Woods BT, Teoh SK, Levisohn L, Mello NK (1994) In vivo proton magnetic resonance spectroscopy detection of human alcohol tolerance. Magn Reson Med 32:511-516.
7. Cuzon Carlson VC, Seabold GK, Helms CM, Garg N, Odagiri M, Rau AR, Daunais J, Alvarez VA, Lovinger DM, Grant KA (2011) Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates. Neuropsychopharmacology 36:2513-2528.
8. De Graaf RA (2007) In vivo NMR spectroscopy: principles and techniques. 2nd ed. John Wiley & Sons, Chichester, West Sussex, England; Hoboken, NJ.
9. Ellingson JS, Taraschi TF, Wu A, Zimmerman R, Rubin E (1988) Cardiolipin from ethanol-fed rats confers tolerance to ethanol in liver mitochondrial membranes. Proc Natl Acad Sci USA 85:3353-3357.
10. Fein G, Meyerhoff DJ (2000) Ethanol in human brain by magnetic resonance spectroscopy: correlation with blood and breath levels, relaxation, and magnetization transfer. Alcohol Clin Exp Res 24:1227-1235.
11. Flory GS, O'Malley J, Grant KA, Park B, Kroenke CD (2010) Quantification of ethanol methyl (1)H magnetic resonance signal intensity following intravenous ethanol administration in primate brain. Methods 50:189-198.
12. Gomez R, Behar KL, Watzl J, Weinzimer SA, Bulanski B, Sanacora G, Koretski J, Guidone E, Jiang L, Petrakis IL, Pittman B, Krystal JH, Mason GF (2012) Intravenous ethanol infusion decreases human cortical gamma-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 Tesla. Biol Psychiatry 71:239-246.
13. Govindaraju V, Meyerhoff DJ, Maudsley AA, Vermathen M, Weiner MW (1997) Effects of brain membranes on 1H nuclear magnetic resonance signal intensity of ethanol in vitro. Alcohol Alcohol 32:671-681.
14. Grant KA (1994) Emerging neurochemical concepts in the actions of ethanol at ligand-gated ion channels. Behav Pharmacol 5:383-404.
15. Grant KA, Leng X, Green HL, Szeliga KT, Rogers LS, Gonzales SW (2008) Drinking typography established by scheduled induction predicts chronic heavy drinking in a monkey model of ethanol self-administration. Alcohol Clin Exp Res 32:1824-1838.
16. Hanstock CC, Rothman DL, Shulman RG, Novotny EJ Jr, Petroff OA, Prichard JW (1990) Measurement of ethanol in the human brain using NMR spectroscopy. J Stud Alcohol 51:104-107.
17. Harris RA, Trudell JR, Mihic SJ (2008) Ethanol's molecular targets. Sci Signal 1:re7.
18. Hetherington HP, Mason GF, Pan JW, Ponder SL, Vaughan JT, Twieg DB, Pohost GM (1994) Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T. Magn Reson Med 32:565-571.
19. Hetherington HP, Pan JW, Mason GF, Adams D, Vaughn MJ, Twieg DB, Pohost GM (1996) Quantitative 1H spectroscopic imaging of human brain at 4.1 T using image segmentation. Magn Reson Med 36:21-29.
20. Hetherington HP, Telang FW, Pan JW, Sammi MK, Schuhlein D, Molina PE, Volkow ND (1999) Spectroscopic imaging of the uptake kinetics of human brain ethanol. Magn Reson Med 42:1019-1026.
21. Kalant H (1971) Absorption, diffusion, distribution, and elimination of ethanol: effects on biological membranes, in The Biology of Alcoholism, Vol. 1, Biochemistry, The Biology of Alcoholism, Vol. 1, Biochemistry (Kissin H, Begleiter H eds), pp 1-62. Plenum, New York.
22. Kaufman MJ, Chiu TM, Mendelson JH, Woods BT, Mello NK, Lukas SE, Fivel PA, Wighton LG (1994) In vivo proton magnetic resonance spectroscopy of alcohol in rhesus monkey brain. Magn Reson Imaging 12:1245-1253.
23. Kaufman MJ, Chiu TM, Mendelson JH, Woods BT, Teoh SK, Eros-Sarnyai M, Mercer G, Mello NK (1996) Brain alcohol detectability increase with repeated administration in humans: a proton spectroscopy study. Magn Reson Med 35:435-440.
24. Khanna JM, Le AD, LeBlanc AE, Shah G (1985) Initial sensitivity versus acquired tolerance to ethanol in rats selectively bred for ethanol sensitivity. Psychopharmacology 86:302-306.
25. Kochunov P, Williamson DE, Lancaster J, Fox P, Cornell J, Blangero J, Glahn DC (2012) Fractional anisotropy of water diffusion in cerebral white matter across the lifespan. Neurobiol Aging 33:9-20.
26. Lebel C, Walker L, Leemans A, Phillips L, Beaulieu C (2008) Microstructural maturation of the human brain from childhood to adulthood. NeuroImage 40:1044-1055.
27. Li TK (2000) Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking. J Stud Alcohol 61:5-12.
28. Mason G, Bendszus M, Meyerhoff D, Hetherington H, Schweinsburg B, Ross B, Taylor M, Krystal J (2005) Magnetic resonance spectroscopic studies of alcoholism: from heavy drinking to alcohol dependence and back again. Alcohol Clin Exp Res 29:150-158.
29. Mendelson JH, Woods BT, Chiu TM, Mello NK, Lukas SE, Teoh SK, Sintavanarong P, Cochin J, Hopkins MA, Dobrosielski M (1990) In vivo proton magnetic resonance spectroscopy of alcohol in human brain. Alcohol 7:443-447.
30. Meyerhoff DJ, Blumenfeld R, Truran D, Lindgren J, Flenniken D, Cardenas V, Chao LL, Rothlind J, Studholme C, Weiner MW (2004) Effects of heavy drinking, binge drinking, and family history of alcoholism on regional brain metabolites. Alcohol Clin Exp Res 28:650-661.
31. Meyerhoff DJ, Rooney WD, Tokumitsu T, Weiner MW (1996) Evidence of multiple ethanol pools in the brain: an in vivo proton magnetization transfer study. Alcohol Clin Exp Res 20:1283-1288.
32. Moxon LN, Rose SE, Haseler LJ, Galloway GJ, Brereton IM, Bore P, Doddrell DM (1991) The visibility of the 1H NMR signal of ethanol in the dog brain. Magn Reson Med 19:340-348.
33. Mugler JP 3rd, Brookeman JR (1990) Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magn Reson Med 15:152-157.
34. Petroff OA, Novotny EJ, Ogino T, Avison M, Prichard JW (1990) In vivo measurements of ethanol concentration in rabbit brain by 1H magnetic resonance spectroscopy. J Neurochem 54:1188-1195.
35. Pfefferbaum A, Lim KO, Zipursky RB, Mathalon DH, Rosenbloom MJ, Lane B, Ha CN, Sullivan EV (1992) Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: a quantitative MRI study. Alcohol Clin Exp Res 16:1078-1089.
36. Pietrzykowski AZ, Treistman SN (2008) The molecular basis of tolerance. Alcohol Res Health 31:298-309.
37. Quertemont E, Green HL, Grant KA (2003) Brain ethanol concentrations and ethanol discrimination in rats: effects of dose and time. Psychopharmacology 168:262-270.
38. Raichle ME, Eichling JO, Straatmann MG, Welch MJ, Larson KB, Ter-Pogossian MM (1976) Blood-brain barrier permeability of 11C-labeled alcohols and 15O-labeled water. Am J Physiol 230:543-552.
39. 2O relaxation in vivo. Magn Reson Med 57:308-318.
40. Sammi MK, Pan JW, Telang FW, Schuhlein D, Molina PE, Volkow ND, Springer CS, Hetherington HP (2000) Measurements of human brain ethanol T2 by spectroscopic imaging at 4T. Magn Reson Med 44:35-40.
41. Schuckit MA (1994) Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry 151:184-189.
42. Schuckit MA (2000) Biological phenotypes associated with individuals at high risk for developing alcohol-related disorders. Part 2. Addict Biol 5:23-36.
43. Schweinsburg BC, Alhassoon OM, Taylor MJ, Gonzalez R, Videen JS, Brown GG, Patterson TL, Grant I (2003) Effects of alcoholism and gender on brain metabolism. Am J Psychiatry 160:1180-1183.
44. Spielman DM, Glover GH, Macovski A, Pfefferbaum A (1993) Magnetic resonance spectroscopic imaging of ethanol in the human brain: a feasibility study. Alcohol Clin Exp Res 17:1072-1077.
45. Taraschi TF, Ellingson JS, Wu A, Zimmerman R, Rubin E (1986) Membrane tolerance to ethanol is rapidly lost after withdrawal: a model for studies of membrane adaptation. Proc Natl Acad Sci USA 83:3669-3673.
46. Vivian JA, Green HL, Young JE, Majerksy LS, Thomas BW, Shively CA, Tobin JR, Nader MA, Grant KA (2001) Induction and maintenance of ethanol self-administration in cynomolgus monkeys (Macaca fascicularis): long-term characterization of sex and individual differences. Alcohol Clin Exp Res 25:1087-1097.
47. Yuan C, O'Connell RJ, Wilson A, Pietrzykowski AZ, Treistman SN (2008) Acute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment. J Biol Chem 283:5090-5098.
48. Zahr NM, Mayer D, Vinco S, Orduna J, Luong R, Sullivan EV, Pfefferbaum A (2009) In vivo evidence for alcohol-induced neurochemical changes in rat brain without protracted withdrawal, pronounced thiamine deficiency, or severe liver damage. Neuropsychopharmacology 34:1427-1442.