Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Xiong, Wei Hong ^a   Duvoisin, Robert M ^a   Adamus, Grazyna ^a   Jeffrey, Brett G ^b   Gellman, Celia ^a   Morgans, Catherine W ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; EPITOPE; IMMUNOGLOBULIN G; TRANSIENT RECEPTOR POTENTIAL CHANNEL M1 AUTOANTIBODY; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; BIOACCUMULATION; CHO CELL; CONTROLLED STUDY; CYTOPLASM; ELECTRORETINOGRAM; HUMAN; IMMUNOREACTIVITY; MELANOMA ASSOCIATED RETINOPATHY; MOUSE; NONHUMAN; PARANEOPLASTIC SYNDROME; PROTEIN DOMAIN; RETINA BIPOLAR GANGLION CELL; WILD TYPE;

ANIMALS; AUTOANTIBODIES; CELL SURVIVAL; CYTOPLASM; ELECTRORETINOGRAPHY; EPITOPES; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; PARANEOPLASTIC SYNDROMES, OCULAR; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RETINAL BIPOLAR CELLS; TRPM CATION CHANNELS;

EID: 84880972920     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069506     Document Type: Article

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