Clinical frailty and long-term mortality in elderly subjects with diabetes

Acta Diabetologica

Volumn 50, Issue 2, 2013, Pages 251-260

  Cacciatore, Francesco ^a,b   Testa, Gianluca ^a,c   Galizia, Gianluigi ^b   Della Morte, David ^d   Mazzella, Francesca ^a,b   Langellotto, Assunta ^a   Pirozzi, Gilda ^a   Ferro, Gaetana ^a   Gargiulo, Gaetano ^a   Ferrara, Nicola ^b,c   Rengo, Franco ^a,b   Abete, Pasquale ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b IRCCS   (Italy)

^c UNIVERSITY OF MOLISE   (Italy)

^d IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

Diabetes; Elderly; Frailty; Mortality

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BODY MASS; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COMORBIDITY; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; FOLLOW UP; FRAIL ELDERLY; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; SEX RATIO; WAIST CIRCUMFERENCE;

AGED; AGED, 80 AND OVER; BODY MASS INDEX; DIABETES MELLITUS; FEMALE; FRAIL ELDERLY; HUMANS; MALE; MULTIVARIATE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SEX FACTORS; WAIST CIRCUMFERENCE;

EID: 84880924635     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-012-0413-2     Document Type: Article

References (33)

1. Narayan KM, Boyle JP, Thompson J (2003) Lifetime risk for diabetes mellitus in the United States. JAMA 290(14):1884-1890. doi: 10.1001/jama.290.14. 1884
2. Zimmet P (1999) Diabetes epidemiology as a trigger to diabetes research. Diabetologia 42(5):499-518
3. Blaum CS, Ofstedal MB, Lana KM, Wray LA (2003) Functional status and health outcomes in older Americans with diabetes mellitus. J Am Geriar Soc 51(6):745-753. doi: 10.1046/j.1365-2389.2003.51256-x
4. Mary SC, Fried LP, Volpato S, Williamson J, Brancati FL, Blaum CS (2004) Patterns of disability related to diabetes mellitus in older women. J Gerontol A Biol Sci Med Sci 59(2):148-153
5. Meneilly GS (2001) Pathophysiology of diabetes in the elderly. In: Sinclair AJ, Finucane P (eds) Diabetes in old age, 2nd edn. Wiley, Chichester, pp 155-164
6. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA, Cardiovascular Health Study Collaborative Research Group (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56(3):M146-M156
7. Strandberg TE, Pitkälä KH (2007) Frailty in elderly people. Lancet 369(9570):1328-1329
8. Cacciatore F, Abete P, Mazzella F, Viati L, Della Morte D, D'Ambrosio D, Gargiulo G, Testa G, Santis D, Galizia G, Ferrara N, Rengo F (2005) Frailty predicts long-term mortality in elderly subjects with chronic heart failure. Eur J Clin Invest 35(12):723-730. doi: 10.1111/j.1365-2362.2005.01572-x
9. Kulminski AM, Ukraintseva SV, Kulminskaya IV, Arbeev KG, Land K, Yashin AI (2008) Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J Am Geriatr Soc 56(1):898-903. doi: 10.1111/j.1532-5415.2008.01656-x
10. Cacciatore F, Gallo C, Ferrara N, Abete P, Paolisso G, Canonico S, Signoriello G, Terracciano C, Napoli C, Varricchio M, Rengo F (2008) Morbidity patterns in aged population in southern Italy. A survey sampling. Arch Gerontol Geriatr 26(3):201-213. doi: 10.1016/S0167-4943(98)00003-x
11. Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373-383
12. Measso G, Cavarzeran F, Zappala G, Lebowitz BD, Crook Th, Pirozzolo FJ, Amaducci LA, Massari D, Grigoletto F (1992) The mini-mental state examination: normative study of an Italian random sample. Dev Neuropsycol 9(2):77-85
13. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO (1983) Development and validation for geriatric depression screening scale: a preliminary report. J Psychiatric Res 17(1):37-49
14. Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW (1963) Studies of illness in the aged. The index of BADL; a standardized measure of biological and psychological functions. JAMA 185:94-99
15. Mazzella F, Cacciatore F, Galizia G, Della-Morte D, Rossetti M, Abbruzzese R et al (2010) Social support and long-term mortality in the elderly: role of comorbidity. Arch Gerontol Geriatr 51(3):323-328. doi: 10.1016/j.archger.2010.01.011
16. Lachs MS, Feinstein AR, Cooney LM Jr, Drickamer MA, Marottoli RA, Pannill FC, Tinetti ME (1990) A simple procedure for general screening for functional disability in elderly patients. Ann Intern Med 112(9):699-706
17. Cacciatore F, Abete P, Maggi S, Luchetti G, Calabrese C, Viati L, Leosco D, Ferrara N, Vitale DF, Rengo F (2004) Disability and 6-year mortality in elderly population. Role of visual impairment. Aging Clin Exp Res 16(5):382-388
18. Cacciatore F, Napoli C, Abete P, Marciano E, Triassi M, Rengo F (1999) Quality of life determinants and hearing function in an elderly population: Osservatorio Geriatrico Campano Study Group. Gerontology 45(6):323-328. doi: 10.1159/000022113
19. Liguori A, Abete P, Hayden JM, Cacciatore F, Rengo F, Ambrosio G, Bonaduce D, Condorelli M, Reaven PD, Napoli C (2001) Effect of glycaemic control and age on low-density lipoprotein susceptibility to oxidation in diabetes mellitus type 1. Eur Heart J 22(22):2075-2084
20. Barnett KN, McMurdo ME, Ogston SA, Morris AD, Evans JM (2006) Mortality in people diagnosed with type 2 diabetes at an older age: a systematic review. Age Ageing 35(5):463-468. doi: 10.1093/ageing/afl019
21. Barnett KN, Ogston SA, McMurdo ME, Morris AD, Evans JM (2010) A 12-year follow-up study of all-cause and cardiovascular mortality among 10,532 people newly diagnosed with Type 2 diabetes in Tayside, Scotland. Diabet Med 27(10):1124-1129. doi: 10.1111/j.1464-5491.2010.03075-x
22. Chin APM, Dekker JM, Feskens EJ, Schouten EG, Kromhout D (1999) How to select a frail elderly population? A comparison of three working definitions. J Clin Epidemiol 52(11):1015-1021
23. Klein BE, Klein R, Knudtson MD, Lee KE (2005) Frailty, morbidity and survival. Arch Gerontol Geriatr 41(2):141-149. doi: 10.1016/j.archger.2005.01. 002
24. Woods NF, LaCroix AZ, Gray SL, Aragaki A, Cochrane BB, Brunner RL, Masaki K, Murray A, Newman AB, Women's Health Initiative (2005) Frailty: emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc 53(8):1321-1330. doi: 10.1111/j.1532-5415. 2005.53405-x
25. Purser JL, Kuchibhatla MN, Fillenbaum GG, Harding T, Peterson ED, Alexander KP (2006) Identifying frailty in hospitalized older adults with significant coronary artery disease. J Am Geriatr Soc 54(11):1674-1681. doi: 10.1111/j.1532-5415.2006.00914-x
26. Newman AB, Simonsick EM, Naydeck BL, Boudreau RM, Kritchevsky SB, Nevitt MC, Pahor M, Satterfield S, Brach JS, Studenski SA, Harris TB (2006) Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA 295(17):2018-2026. doi: 10.1001/jama.295.17.2018
27. Hubbard RE, Andrew MK, Fallah N, Rockwood K (2010) Comparison of the prognostic importance of diagnosed diabetes, co-morbidity and frailty in older people. Diabet Med 27(5):603-606. doi: 10.1111/j.1464-5491.2010.02977-x
28. Park SW, Goodpaster BH, Strotmeyer ES, de Rekeneire N, Harris TB, Schwartz AV, Tylavsky FA, Newman AB (2006) Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes 55(6):1813-1818. doi: 10.2337/db05-1183
29. De Rekeneire N, Resnick HE, Schwartz AV, Shorr RI, Kuller LH, Simonsick EM, Vellas B, Harris TB, Health, Aging, and Body Composition Study (2003) Diabetes is associated with subclinical functional limitation in nondisabled older individuals: the Health, Aging, and Body Composition study. Diabetes Care 26(12):3257-3263. doi: 10.2337/diacare.26.12.3257
30. Visser M, Schaap LA (2011) Consequences of sarcopenia. Clin Geriatr Med 27(3):387-399. doi: 10.1016/j.cger.2011.03.006
31. Mitnitski A, Song X, Skoog I, Broe GA, Cox JL, Grunfeld E, Rockwood K (2005) Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc 53(12):2184-2189. doi: 10.1111/j.1532-5415.2005.00506.x
32. Syddall H, Roberts HC, Evandrou M, Cooper C, Bergman H, Aihie Sayer A (2010) Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study. Age Ageing 39(2):197-203. doi: 10.1093/ageing/afp204
33. Hubbard RE, Rockwood K (2011) Frailty in older women. Maturitas 69(3):203-207. doi: 10.1016/j.maturitas.2011.04.006