Synthesis of the first conjugates of 5-ethynyl-2′-deoxyuridine with closo-dodecaborate and cobalt-bis-dicarbollide boron clusters

Tetrahedron

Volumn 69, Issue 37, 2013, Pages 8034-8041

  Semioshkin, Andrey ^a   Ilinova, Anna ^a   Lobanova, Irina ^a   Bregadze, Vladimir ^a   Paradowska, Edyta ^b   Studzińska, Mirosława ^b   Jabłońska, Agnieszka ^b   Lesnikowski, Zbigniew J ^b  

^a A N NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS   (Russian Federation)

^b INSTITUTE OF MEDICAL BIOLOGY   (Poland)

Author keywords

5 Ethynyl 2 deoxyuridine; Boron cluster conjugates; Closo dodecaborate; Cobalt bis dicarbollide; Cytotoxicity; Oxonium derivatives

Indexed keywords

2 [N [2 (4 (2' DEOXYURIDINE 5 YL) 2 METHYLBUT 3 YN 2 YLOXY)ETHYL]DIMETHYLAMMONIO]ETHOXY CLOSO UNDECAHYDRODODECABORATE; 4 [N [2 (4 (2' DEOXYURIDINE 5 YL) 2 METHYLBUT 3 YN 2 YLOXY)ETHYL]DIMETHYLAMMONIO]BUTOXY CLOSO UNDECAHYDRODODECABORATE; 5 [N [2 (4 (2' DEOXYURIDINE 5 YL) 2 METHYLBUT 3 YN 2 YLOXY)ETHYL]DIMETHYLAMMONIO]PENTYLOXY CLOSO UNDECAHYDRODODECABORATE; 8 [2 [N (2 (2 (4 (2 DEOXYURIDINE 5 YL) 2 METHYLBUT 3 YN 2YL OXY)ETHYL)DIMETHYLAMMONIO)ETHOXY]ETHOXY] (H) 1,10,2,20 TETRACARBA 3 COMMO COBALTA CLOSO TRICOSABORATE; ACICLOVIR; ANTIVIRUS AGENT; BORON DERIVATIVE; CIDOFOVIR; COBALT DERIVATIVE; DEOXYURIDINE DERIVATIVE; GANCICLOVIR; NUCLEOSIDE; UNCLASSIFIED DRUG;

ALKYNYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CONJUGATE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENCEPHALOMYOCARDITIS VIRUS; HERPES SIMPLEX VIRUS 1; HUMAN CYTOMEGALOVIRUS; NEUTRON CAPTURE THERAPY; NONHUMAN; PARAINFLUENZA VIRUS 3; PRIORITY JOURNAL; SONOGASHIRA REACTION; VESICULAR STOMATITIS VIRUS;

EID: 84880920663     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2013.06.100     Document Type: Article

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