Prediction of relaxin-3-induced downstream pathway resulting in anxiolytic-like behaviors in rats based on a microarray and peptidome analysis

Journal of Receptors and Signal Transduction

Volumn 33, Issue 4, 2013, Pages 224-233

  Nakazawa, Chihiro Miyamoto ^a   Shikata, Kohdoh ^a   Uesugi, Mai ^a   Katayama, Hiroyuki ^b   Aoshima, Ken ^a   Tahara, Kazuhiro ^a   Takahashi, Eiki ^c   Hida, Takayuki ^a   Shibata, Hisashi ^d   Ogura, Hiroo ^a   Seiki, Takashi ^a   Oda, Yoshiya ^b   Kuromitsu, Junro ^a   Miyamoto, Norimasa ^a  

^a EISAI CO LTD   (Japan)

^b EISAI INC   (United States)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d Sunplanet Co Ltd   (Japan)

Author keywords

Anxiety; Elevated plus maze test; Feeding; Oxytocin; Proteome; Shock probe burying test

Indexed keywords

OXYTOCIN; RELAXIN 3; NERVE PROTEIN; NEUROPEPTIDE; RELAXIN; RELAXIN-3, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BRAIN REGION; COGNITION; CONTROLLED STUDY; FEAR; FEEDING BEHAVIOR; GENE EXPRESSION; GENE PRODUCT; HABITUATION; HYPOTHALAMUS; INFUSION; INTRACELLULAR SIGNALING; LOCOMOTION; MALE; MASS SPECTROMETRY; MAZE TEST; MICROARRAY ANALYSIS; NONHUMAN; PEPTIDOMICS; PHENOTYPE; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; STRESS; TRANQUILIZING ACTIVITY; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; DRUG EFFECTS; DRUG THERAPY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; HYPOTHALAMUS; INJECTIONS, INTRAVENTRICULAR; MAZE LEARNING; MICROARRAY ANALYSIS; NERVE TISSUE PROTEINS; NEUROPEPTIDES; OXYTOCIN; RATS; RELAXIN; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 84880893173     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2012.756895     Document Type: Article

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