Clinical validation of a highly sensitive GC-MS platform for routine urine drug screening and real-time reporting of up to 212 drugs

Journal of Toxicology

Volumn 2013, Issue , 2013, Pages

  Nair, Hari ^a   Woo, Fred ^a   Hoofnagle, Andrew N ^a   Baird, Geoffrey S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ARTICLE; COMPUTER PROGRAM; DATA PROCESSING; DRUG SCREENING; DRUG URINE LEVEL; HUMAN; INSTRUMENT VALIDATION; INTERMETHOD COMPARISON; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS; TEMPERATURE; VAPORIZER;

EID: 84880888372     PISSN: 16878191     EISSN: 16878205     Source Type: Journal    
DOI: 10.1155/2013/329407     Document Type: Article

References (16)

1. Peters F. T., Recent advances of liquid chromatography-(tandem) mass spectrometry in clinical and forensic toxicology. Clinical Biochemistry 2011 44 1 54 65 2-s2.0-78650864016 10.1016/j.clinbiochem.2010.08.008
2. Wu A. H., French D., Implementation of liquid chromatography/mass spectrometry into the clinical laboratory. Clinica Chimica Acta 2013 420 4 10 10.1016/j.cca.2012.10.026
3. Grebe S. K. G., Singh R. J., LC-MS/MS in the clinical laboratory-where to from here? Clinical Biochemist Reviews 2011 32 1 5 31 2-s2.0-80052539443
4. Wu A. H., Role of liquid chromatography-high-resolution mass spectrometry (LC-HR/MS) in clinical toxicology. Clinical Toxicology 2012 50 8 733 742 10.3109/15563650.2012.713108
5. Maurer H. H., Current role of liquid chromatography-mass spectrometry in clinical and forensic toxicology. Analytical and Bioanalytical Chemistry 2007 388 7 1315 1325 2-s2.0-34547294263 10.1007/s00216-007-1248-5 (Pubitemid 47150863)
6. Maurer H. H., Hyphenated mass spectrometric techniques-indispensable tools in clinical and forensic toxicology and in doping control. Journal of Mass Spectrometry 2006 41 11 1399 1413 2-s2.0-33845340097 10.1002/jms.1112 (Pubitemid 44875650)
7. Krasowski M. D., Pizon A. F., Siam M. G., Giannoutsos S., Iyer M., Ekins S., Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine. BMC Emergency Medicine 2009 9, article 5 2-s2.0-66749177754 10.1186/1471-227X-9-5
8. Schymanski E. L., Meringer M., Brack W., Automated strategies to identify compounds on the basis of GC/EI-MS and calculated properties. Analytical Chemistry 2011 83 3 903 912 2-s2.0-79952144532 10.1021/ac102574h
9. McLafferty F. W., Turecek F., Interpretation of Mass Spectra 1993 4th USB
10. Matisová E., Dömötörová M., Fast gas chromatography and its use in trace analysis. Journal of Chromatography A 2003 1000 1-2 199 221 10.1016/S0021-9673(03)00310-8 (Pubitemid 36638459)
11. Stein S. E., An integrated method for spectrum extraction and compound identification from gas chromatography/mass spectrometry data. Journal of the American Society for Mass Spectrometry 1999 10 8 770 781 2-s2.0-0033452842 10.1016/S1044-0305(99)00047-1 (Pubitemid 34506228)
12. http://chemdata.nist.gov/mass-spc/amdis/index.html
13. Meyer M. R., Peters F. T., Maurer H. H., Automated mass spectral deconvolution and identification system for GC-MS screening for drugs, poisons, and metabolites in urine. Clinical Chemistry 2010 56 4 575 584 2-s2.0-77950570852 10.1373/clinchem.2009.135517
14. Behrends V., Tredwell G. D., Bundy J. G., A software complement to AMDIS for processing GC-MS metabolomic data. Analytical Biochemistry 2011 415 2 206 208 2-s2.0-79958273162 10.1016/j.ab.2011.04.009
15. Choea S., WooDong S. H., Park W. K., Choia H., Hwang B. Y., Lee D., Kim S., Development of a target component extraction method from GC-MS data with an in-house program for metabolite profiling. Analytical Biochemistry 2012 426 2 94 102 10.1016/j.ab.2012.04.010
16. Callaghan S.O., Souza D.P., Isaac A., PyMS: A Python toolkit for processing of gas chromatography-mass spectrometry (GC-MS) data. Application and comparative study of selected tools, BMC Bioinformatics 2012, 10.1186/1471-2105-13-115, 13115