Phyllanflexoid C: First example of phenylacetylene-bearing 18-nor-diterpenoid glycoside from the roots of Phyllanthus flexuosus

Tetrahedron Letters

Volumn 54, Issue 35, 2013, Pages 4670-4674

  Zhao, Jian Qiang ^a,b   Lv, Jun Jiang ^a,b   Wang, Yan Ming ^a,b   Xu, Min ^a   Zhu, Hong Tao ^a   Wang, Dong ^a   Yang, Chong Ren ^a   Wang, Yi Fei ^c   Zhang, Ying Jun ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Guangzhou Jinan Biomedicine Research and Development Center   (China)

Author keywords

18 Nor diterpenoid glycoside; Cytotoxic activity; Phenylacetylene; Phyllanflexoids A C; Phyllanthus flexuosus

Indexed keywords

CLEISTANTHOL; DITERPENOID; PHENYLACETYLENE; PHYLLANFLEXOID A; PHYLLANFLEXOID B; PHYLLANFLEXOID C; PHYLLANTHUS FLEXUOSUS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG ISOLATION; DRUG STRUCTURE; ESOPHAGUS CANCER; HUMAN; HUMAN CELL; IC 50; PHYLLANTHUS; PHYLLANTHUS FLEXUOSUS; PLANT ROOT; STEREOCHEMISTRY;

PHYLLANTHUS FLEXUOSUS;

EID: 84880837631     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2013.06.082     Document Type: Article

References (30)

1. D.W. Unander, G.L. Webster, and B.S. Blumberg J. Ethnopharmacol. 45 1995 1 18
2. N.A. Shakil, J. Pankaj Kumar, R.K. Pandey, and D.B Saxena Phytochemistry 69 2008 759 764
3. J.L. Mensah, J. Gleye, C. Moulis, and I. Fouraste J. Nat. Prod. 51 1988 1113 1115
4. Y.J. Zhang, T. Tanaka, Y. Iwamoto, C.R. Yang, and I. Kouno J. Nat. Prod. 63 2000 1507 1510
5. Y.J. Zhang, T. Tanaka, Y. Iwamoto, C.R. Yang, and I. Kouno Tetrahedron Lett. 41 2000 1781 1784
6. R. Ratnayake, D. Covell, T.T. Ransom, K.R. Gustafson, and J.A. Beutler Org. Lett. 11 2008 57 60
7. Y.J. Zhang, T. Tanaka, Y. Iwamoto, C.R. Yang, and I. Kouno J. Nat. Prod. 64 2001 870 873
8. Q. Liu, Y.F. Wang, R.J. Chen, M.Y. Zhang, Y.F. Wang, C.R. Yang, and Y.J. Zhang J. Nat. Prod. 72 2009 969 972
9. C.C. Chang, Y.C. Lien, C.S. Karin, C. Liu, and S.S. Lee Phytochemistry 63 2003 825 833
10. Y.J. Zhang, T. Abe, T. Tanaka, C.R. Yang, and I. Kouno J. Nat. Prod. 64 2001 1527 1532
11. G.R. Pettit, D.E. Schaufelberger, R.A. Nieman, C. Dufresne, and J.A. Saenz-Renauld J. Nat. Prod. 53 1990 1143 1406
12. R. Tanaka, Y. In, T. Ishida, and S. Matsunaga J. Nat. Prod. 57 1994 1523 1528
13. R. Tanaka, K. Masuda, and S. Matsunaga Phytochemistry 32 1993 472 474
14. T. Yoshida, H. Itoh, S. Matsunaga, R. Tanaka, and T. Okuda Chem. Pharm. Bull. 40 1992 53 60
15. R. Tanaka, M. Tabuse, and S. Matsunaga Phytochemistry 27 1988 3563 3567
16. R. Tanaka, and S. Matsunaga Phytochemistry 27 1988 2273 2277
17. S. Wada, A. Iida, and R. Tanaka J. Nat. Prod. 64 2001 1545 1547
18. S. Sutthivaiyakit, N.N. Nakorn, W. Kraus, and P. Sutthivaiyakit Tetrahedron 59 2003 9991 9995
19. E.J. McGarry, K.H. Pegel, L. Phillips, and E.S. Waight J. Chem. Soc. C 1971 904 909
20. E.J. McGarry, K.H. Pegel, L. Phillips, and E.S. Waight J. Chem. Soc., Chem. Commun. 1074 1969
21. L.A. Maslovskaya, A.I. Savchenko, V.A. Gordon, P.W. Reddell, C.J. Pierce, P.G. Parsons, and C.M. Williams Org. Lett. 13 2011 1032 1035
22. R.W. Denton, W.W. Harding, C.I. Anderson, H. Jacobs, S. McLean, and W.F. Reynolds J. Nat. Prod. 64 2001 829 831
23. Gaussian 09, Revision A.1; Gaussian, Inc.: Wallingford, CT, 2009. A full list of authors can be found in the Supplementary data.
24. P.J. Stephens, J.J. Pan, and K. Krohn J. Org. Chem. 72 2007 7641 7649
25. I.N. Siddiqui, A. Zahoor, H. Hussain, I. Ahmed, V.U. Ahmad, D. Padula, S. Draeger, B. Schulz, K. Meier, M. Steinert, T. Kurtan, U. Floerke, G. Pescitelli, and K. Krohn J. Nat. Prod. 74 2011 365 373
26. R.E. Minto, and B. Blacklock J. Prog. Lipid Res. 47 2008 233 306
27. D.W. Reed, D.R. Polichuk, P.H. Buist, S.J. Ambrose, R.J. Sasata, C.K. Savile, A.R.S. Ross, and P.S. Covello J. Am. Chem. Soc. 125 2003 10635 10640
28. A.A. Craveiro, and E.R. Silveira Phytochemistry 21 1982 2571 2574
29. A.C. Pinto, M.L. Patitucci, R.S. Da Silva, P.P.S. Queiroz, and A. Kelecom Tetrahedron 39 1983 3351 3354
30. A.C. Pinto, D.H.T. Zocher, P.P.S. Queiroz, and A. Kelecom Phytochemistry 26 1987 2409 2411