Comparison of the diagnostic accuracy of measured and calculated free cortisol in acutely ill patients using the Coolens equation

Critical Care and Resuscitation

Volumn 15, Issue 1, 2013, Pages 39-41

  Cohen, Jeremy ^a   Venkatesh, Bala ^b,c   Tan, Terrence ^c,d  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c PRINCESS ALEXANDRA HOSPITAL   (Australia)

^d WESLEY HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE;

ACUTE DISEASE; ARTICLE; BLOOD; COMPARATIVE STUDY; HUMAN; MATHEMATICS; PROSPECTIVE STUDY; REPRODUCIBILITY; SEPTIC SHOCK;

ACUTE DISEASE; HUMANS; HYDROCORTISONE; MATHEMATICS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SHOCK, SEPTIC;

MLCS; MLOWN;

EID: 84880806400     PISSN: 14412772     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Hamrahian AH, Oseni TS, Arafah BM. Measurements of serum free cortisol in critically ill patients. N Engl J Med 2004; 350: 1629-38.
2. Ho JT, Al-Musalhi H, Chapman MJ, et al. Septic shock and sepsis: a comparison of total and free plasma cortisol levels. J Clin Endocrinol Metab 2006; 91: 105-14.
3. Coolens J-L, Van Baelen H, Heyns W. Clinical use of unbound plasma cortisol as calculated from total cortisol and corticosteroidbinding globulin. J Steroid Biochem 1987; 26: 197-202.
4. McWhinney BC, Briscoe SE, Ungerer JP, Pretorius CJ. Measurement of cortisol, cortisone, prednisolone, dexamethasone and 11-deoxy- cortisol with ultra high performance liquid chromatography-tan- dem mass spectrometry: application for plasma, plasma ultrafiltrate, urine and saliva in a routine laboratory. J Chromatogr B Analyt Technol Biomed Life Sci 2010; 878: 2863-9.
5. Cohen J, Lassig-Smith M, Deans R, et al. Serial changes in plasma total cortisol, plasma free cortisol and tissue cortisol activity in patients with septic shock. An observational study. Shock 2012; 37: 28-33.
6. Tan T, Chang L, Woodward A, et al. Characterising adrenal function using directly measured plasma free cortisol in stable severe liver disease. J Hepatol 2010; 53: 841-8.
7. Mueller UW, Potter JM. Binding of cortisol to human albumin and serum: the effect of protein concentration. Biochem Pharmacol 1981; 30: 727-33.
8. Emptoz-Bonneton A, Cousin P, Seguchi K, et al. Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity. J Clin Endocrinol Metab 2000; 85: 361-7.
9. Dorin RI, Pai HK, Ho JT, et al. Validation of a simple method of estimating plasma free cortisol: role of cortisol binding to albumin. Clin Biochem 2009; 42: 64-71.
10. Pretorius CJ, Galligan JP, McWhinney BC, et al. Free cortisol method comparison: ultrafiltration, equilibrium dialysis, tracer dilution, tandem mass spectrometry and calculated free cortisol. Clin Chim Acta 2011; 412: 1043-7.
11. Barlow NL, Holme J, Stockley RA, Clark PM. An evaluation of measured and calculated serum free cortisol in a group of patients with known adrenal suppression. Ann Clin Biochem 2010; 47: 200-4.