Regulation of Nucleotide Excision Repair by Nuclear Lamin B1

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Butin Israeli, Veronika ^a   Adam, Stephen A ^a   Goldman, Robert D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN; LAMIN B1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; EXCISION REPAIR; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

EID: 84880805342     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069169     Document Type: Article

References (55)

1. Dechat T, Adam SA, Taimen P, Shimi T, Goldman RD, (2010) Nuclear lamins. Cold Spring Harb Perspect Biol 2: a000547.
2. Stewart C, Burke B, (1987) Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B. Cell. 51: 383-392.
3. Dittmer TA, Misteli T, (2011) The lamin protein family. Genome Biol 12: 222.
4. Shimi T, Butin-Israeli V, Goldman RD, (2012) The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm. Curr Opin Cell Biol 24: 71-78.
5. Liu Y, Rusinol A, Sinensky M, Wang Y, Zou Y, (2006) DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A. J Cell Sci. 119: 4644-4649.
6. Varela I, Cadinanos J, Pendas AM, Gutierrez-Fernandez A, Folgueras AR, et al. (2005) Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature 437: 564-568.
7. Liu Y, Wang Y, Rusinol AE, Sinensky MS, Liu J, et al. (2008) Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A. FASEB J. 22: 603-611.
8. Padiath QS, Saigoh K, Schiffmann R, Asahara H, Yamada T, et al. (2006) Lamin B1 duplications cause autosomal dominant leukodystrophy. Nat Genet 38: 1114-1123.
9. Brussino A, Vaula G, Cagnoli C, Panza E, Seri M, et al. (2010) A family with autosomal dominant leukodystrophy linked to 5q23.2-q23.3 without lamin B1 mutations. Eur J Neurol 17: 541-549.
10. Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, et al. (2010) Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A 107: 5076-5081.
11. Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, et al. (2011) Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell 22: 4683-4693.
12. Kim Y, Sharov AA, McDole K, Cheng M, Hao H, et al. (2011) Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science 334: 1706-1710.
13. Yang SH, Chang SY, Yin L, Tu Y, Hu Y, et al. (2011) An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair. Hum Mol Genet 20: 3537-3544.
14. Moss SF, Krivosheyev V, de Souza A, Chin K, Gaetz HP, et al. (1999) Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms. Gut 45: 723-729.
15. Broers JL, Raymond Y, Rot MK, Kuijpers H, Wagenaar SS, et al. (1993) Nuclear A-type lamins are differentially expressed in human lung cancer subtypes. Am J Pathol 143: 211-220.
16. Dreesen O, Chojnowski A, Ong PF, Zhao TY, Common JE, et al. (2013) Lamin B1 fluctuations have differential effects on cellular proliferation and senescence. J Cell Biol 200: 605-617.
17. Shimi T, Butin-Israeli V, Adam SA, Hamanaka RB, Goldman AE, et al. (2011) The role of nuclear lamin B1 in cell proliferation and senescence. Genes Dev 25: 2579-2593.
18. Freund A, Laberge RM, Demaria M, Campisi J, (2012) Lamin B1 loss is a senescence-associated biomarker. Mol Biol Cell 23: 2066-2075.
19. Barascu A, Le Chalony C, Pennarun G, Genet D, Imam N, et al. (2012) Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation. EMBO J 31: 1080-1094.
20. Shimi T, Pfleghaar K, Kojima S, Pack CG, Solovei I, et al. (2008) The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev 22: 3409-3421.
21. Laemmli UK, (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
22. Moir RD, Montag-Lowy M, Goldman RD, (1994) Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication. J Cell Biol 125: 1201-1212.
23. Komatsu Y, Tsujino T, Suzuki T, Nikaido O, Ohtsuka E, (1997) Antigen structural requirements for recognition by a cyclobutane thymine dimer-specific monoclonal antibody. Nucleic Acids Res 25: 3889-3894.
24. Sugasawa K, Okuda Y, Saijo M, Nishi R, Matsuda N, et al. (2005) UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell 121: 387-400.
25. Yamamoto A, Nakamura Y, Kobayashi N, Iwamoto T, Yoshioka A, et al. (2007) Neurons and astrocytes exhibit lower activities of global genome nucleotide excision repair than do fibroblasts. DNA Repair (Amst) 6: 649-657.
26. Butin-Israeli V, Drayman N, Oppenheim A, (2010) Simian virus 40 infection triggers a balanced network that includes apoptotic, survival, and stress pathways. J Virol 84: 3431-3442.
27. Jiang K, Pereira E, Maxfield M, Russell B, Goudelock DM, et al. (2003) Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. J Biol Chem 278: 25207-25217.
28. Martin SA, Lord CJ, Ashworth A, (2008) DNA repair deficiency as a therapeutic target in cancer. Curr Opin Genet Dev 18: 80-86.
29. Yang XH, Zou L, (2009) Dual functions of DNA replication forks in checkpoint signaling and PCNA ubiquitination. Cell Cycle 8: 191-194.
30. Nam EA, Cortez D, (2011) ATR signalling: more than meeting at the fork. Biochem J 436: 527-536.
31. Chang LM, Bollum FJ, (1986) Molecular biology of terminal transferase. CRC Crit Rev Biochem 21: 27-52.
32. Lagerwerf S, Vrouwe MG, Overmeer RM, Fousteri MI, Mullenders LH, (2011) DNA damage response and transcription. DNA Repair (Amst) 10: 743-750.
33. Sertic S, Pizzi S, Lazzaro F, Plevani P, Muzi-Falconi M, (2012) NER and DDR: classical music with new instruments. Cell Cycle 11: 668-674.
34. Lukas J, Lukas C, Bartek J, (2011) More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol 13: 1161-1169.
35. Cleaver JE, (2011) gammaH2Ax: biomarker of damage or functional participant in DNA repair "all that glitters is not gold!". Photochem Photobiol 87: 1230-1239.
36. Sugasawa K, (2011) Multiple DNA damage recognition factors involved in mammalian nucleotide excision repair. Biochemistry (Mosc) 76: 16-23.
37. Lee KY, Myung K, (2008) PCNA modifications for regulation of post-replication repair pathways. Mol Cells 26: 5-11.
38. Prakash S, Johnson RE, Prakash L, (2005) Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem 74: 317-353.
39. Walmacq C, Cheung AC, Kireeva ML, Lubkowska L, Ye C, et al. (2012) Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Mol Cell 46: 18-29.
40. FitzGerald JE, Grenon M, Lowndes NF, (2009) 53BP1: function and mechanisms of focal recruitment. Biochem Soc Trans 37: 897-904.
41. Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, et al. (2009) Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response. J Cell Biol 186: 835-847.
42. Muralikrishna B, Chaturvedi P, Sinha K, Parnaik VK, (2012) Lamin misexpression upregulates three distinct ubiquitin ligase systems that degrade ATR kinase in HeLa cells. Mol Cell Biochem 365: 323-332.
43. Musich PR, Zou Y, (2009) Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. Aging (Albany NY). 1: 28-37.
44. Sinensky M, Fantle K, Trujillo M, McLain T, Kupfer A, et al. (1994) The processing pathway of prelamin A. J Cell Sci 107 (Pt. 1): 61-67.
45. Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, et al. (2003) Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature 423: 293-298.
46. Constantinescu D, Csoka AB, Navara CS, Schatten GP, (2010) Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts. Exp Cell Res 316: 2747-2759.
47. Toledo LI, Murga M, Gutierrez-Martinez P, Soria R, Fernandez-Capetillo O, (2008) ATR signaling can drive cells into senescence in the absence of DNA breaks. Genes Dev 22: 297-302.
48. Osorio FG, Barcena C, Soria-Valles C, Ramsay AJ, de Carlos F, et al. (2012) Nuclear lamina defects cause ATM-dependent NF-kappaB activation and link accelerated aging to a systemic inflammatory response. Genes Dev 26: 2311-2324.
49. Overmeer RM, Moser J, Volker M, Kool H, Tomkinson AE, et al. (2011) Replication protein A safeguards genome integrity by controlling NER incision events. J Cell Biol 192: 401-415.
50. d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, et al. (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426: 194-198.
51. Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, et al. (2009) Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol 11: 973-979.
52. Guelen L, Pagie L, Brasset E, Meuleman W, Faza MB, et al. (2008) Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature 453: 948-951.
53. Zullo JM, Demarco IA, Pique-Regi R, Gaffney DJ, Epstein CB, et al. (2012) DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell 149: 1474-1487.
54. Muck JS, Kandasamy K, Englmann A, Gunther M, Zink D, (2012) Perinuclear positioning of the inactive human cystic fibrosis gene depends on CTCF, A-type lamins and an active histone deacetylase. J Cell Biochem 113: 2607-2621.
55. Tang CW, Maya-Mendoza A, Martin C, Zeng K, Chen S, et al. (2008) The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells. J Cell Sci 121: 1014-1024.