Thyroxin treatment protects against white matter injury in the immature brain via brain-derived neurotrophic factor

Stroke

Volumn 44, Issue 8, 2013, Pages 2275-2283

  Hung, Pi Lien ^a   Huang, Chao Ching ^b   Huang, Hsiu Mei ^a   Tu, Dom Gene ^c   Chang, Ying Chao ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c CHIA YI CHRISTIAN HOSPITAL   (Taiwan)

Author keywords

brain derived neurotrophic factor; hypoxic ischemia; immature brain; thyroxin; white matter injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; LEVOTHYROXINE; MYELIN BASIC PROTEIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; AXONAL INJURY; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN VENTRICLE DILATATION; CELL SURVIVAL; CLIMBING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOTOR PERFORMANCE; MYELINATION; NEUROPROTECTION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUP (RODENT); RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WALKING; WHITE MATTER INJURY;

BRAIN-DERIVED NEUROTROPHIC FACTOR; HYPOXIC ISCHEMIA; IMMATURE BRAIN; THYROXIN; WHITE MATTER INJURY;

ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; HYPOXIA-ISCHEMIA, BRAIN; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENTRICULAR; LEUKOENCEPHALOPATHIES; MALE; NEUROPROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; RECEPTOR, TRKB; THYROXINE; UP-REGULATION;

EID: 84880786664     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.001552     Document Type: Article

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