Variations within Class-A β-Lactamase Physiochemical Properties Reflect Evolutionary and Environmental Patterns, but not Antibiotic Specificity

PLoS Computational Biology

Volumn 9, Issue 7, 2013, Pages

  Verma, Deeptak ^a   Jacobs, Donald J ^b   Livesay, Dennis R ^a  

^a University of North Carolina at Charlotte   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; ELECTROSTATICS; ENZYMES; PHYLOGENETIC;

BACTERIAL ENZYMES; CLASS A; DIFFERENT CLASS; ELECTROSTATIC POTENTIAL MAPS; EVOLUTIONARY HISTORY; PHYSIO-CHEMICAL PROPERTIES; PROPERTY; SYSTEMATIC VARIATION; WITHIN CLASS; Β-LACTAMASE;

ANTIBIOTICS;

ANTIBIOTIC AGENT; BETA LACTAMASE; CEPHALOSPORIN DERIVATIVE; MONOBACTAM DERIVATIVE; PENICILLIN DERIVATIVE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS LICHENIFORMIS; ELECTRIC POTENTIAL; ENTEROBACTER CLOACAE; ENVIRONMENTAL FACTOR; ESCHERICHIA COLI; EVOLUTION; HYDROGEN BOND; HYDROLYSIS; KLEBSIELLA PNEUMONIAE; NONHUMAN; PHYLOGENY; PHYSICAL CHEMISTRY; PSEUDOMONAS AERUGINOSA; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS MALTOPHILIA; STREPTOMYCES ALBUS;

BACTERIA (MICROORGANISMS);

EID: 84880785856     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003155     Document Type: Article

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