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Volumn 15, Issue 4, 2013, Pages 356-371

Current and future treatments for malignant pheochromocytoma and sympathetic paraganglioma

Author keywords

Chemotherapy; Malignant paraganglioma; Malignant pheochromocytoma; Metaiodobenzylguanidine; Molecular targeted therapies; Surgery

Indexed keywords

(3 IODOBENZYL)GUANIDINE; ANGIOGENESIS INHIBITOR; CD135 ANTIGEN; DENOSUMAB; DOXAZOSIN; FLUORODEOXYGLUCOSE; PAZOPANIB; PHENOXYBENZAMINE; PLATELET DERIVED GROWTH FACTOR; PRAZOSIN; SUCCINATE DEHYDROGENASE; SUNITINIB; TERAZOSIN; VASCULOTROPIN;

EID: 84880781044     PISSN: 15233790     EISSN: 15346269     Source Type: Journal    
DOI: 10.1007/s11912-013-0320-x     Document Type: Article
Times cited : (132)

References (99)
  • 1
    • 79952300359 scopus 로고    scopus 로고
    • Clinical risk factors for malignancy and overall survival in patients with pheochromocytomas and sympathetic paragangliomas: Primary tumor size and primary tumor location as prognostic indicators
    • 21190975 10.1210/jc.2010-1946 1:CAS:528:DC%2BC3MXjvFahsbc%3D To date, this is the largest published study on clinical predictors of malignancy
    • • Ayala-Ramirez M, Feng L, Johnson MM, Ejaz S, Habra MA, Rich T, et al. Clinical risk factors for malignancy and overall survival in patients with pheochromocytomas and sympathetic paragangliomas: Primary tumor size and primary tumor location as prognostic indicators. J Clin Endocrinol Metab. 2011;96(3):717-25. To date, this is the largest published study on clinical predictors of malignancy.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.3 , pp. 717-725
    • Ayala-Ramirez, M.1    Feng, L.2    Johnson, M.M.3    Ejaz, S.4    Habra, M.A.5    Rich, T.6    Busaidy, N.7    Cote, G.J.8    Perrier, N.9    Phan, A.10
  • 3
    • 70350378805 scopus 로고    scopus 로고
    • Treatment of malignant pheochromocytoma
    • 19672813 10.1055/s-0029-1231025 1:CAS:528:DC%2BD1MXhtlalt7%2FI
    • Adjalle R, Plouin PF, Pacak K, Lehnert H. Treatment of malignant pheochromocytoma. Horm Metab Res. 2009;41(9):687-96.
    • (2009) Horm Metab Res , vol.41 , Issue.9 , pp. 687-696
    • Adjalle, R.1    Plouin, P.F.2    Pacak, K.3    Lehnert, H.4
  • 4
    • 77957328257 scopus 로고    scopus 로고
    • Malignant pheochromocytoma metastasis to the breast shown on I-123 MIBG scan
    • 20838297 10.1097/RLU.0b013e3181ef0af1
    • Patel M, Santos P, Jong I, Nandurkar D, McKay J. Malignant pheochromocytoma metastasis to the breast shown on I-123 MIBG scan. Clin Nucl Med. 2010;35(10):816-7.
    • (2010) Clin Nucl Med , vol.35 , Issue.10 , pp. 816-817
    • Patel, M.1    Santos, P.2    Jong, I.3    Nandurkar, D.4    McKay, J.5
  • 5
    • 0036560193 scopus 로고    scopus 로고
    • Malignant pheochromocytoma with cutaneous metastases presenting with hemolytic anemia and pyrexia of unknown origin
    • 12186139 1:STN:280:DC%2BD38vivF2hsQ%3D%3D
    • Srinivasan R, Kini U, Babu MK, Jayaseelan E, Pradeep R. Malignant pheochromocytoma with cutaneous metastases presenting with hemolytic anemia and pyrexia of unknown origin. J Assoc Physicians India. 2002;50(5):731-3.
    • (2002) J Assoc Physicians India , vol.50 , Issue.5 , pp. 731-733
    • Srinivasan, R.1    Kini, U.2    Babu, M.K.3    Jayaseelan, E.4    Pradeep, R.5
  • 8
    • 33747638645 scopus 로고    scopus 로고
    • Should patients with apparently sporadic pheochromocytomas or paragangliomas be screened for hereditary syndromes?
    • DOI 10.1210/jc.2005-2178
    • Jimenez C, Cote G, Arnold A, Gagel RF. Review: Should patients with apparently sporadic pheochromocytomas or paragangliomas be screened for hereditary syndromes? J Clin Endocrinol Metab. 2006;91(8):2851-8. (Pubitemid 44271723)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.8 , pp. 2851-2858
    • Jimenez, C.1    Cote, G.2    Arnold, A.3    Gagel, R.F.4
  • 9
    • 84858703890 scopus 로고    scopus 로고
    • Prevalence and spectrum of SDHx mutations in pheochromocytoma and paraganglioma in patients from belgium: An update
    • 22566194 10.1055/s-0032-1311610 1:CAS:528:DC%2BC38XpvFKntr8%3D
    • Persu A, Lannoy N, Maiter D, Mendola A, Montigny P, Oriot P, et al. Prevalence and spectrum of SDHx mutations in pheochromocytoma and paraganglioma in patients from belgium: An update. Horm Metab Res. 2012;44(5):349-53.
    • (2012) Horm Metab Res , vol.44 , Issue.5 , pp. 349-353
    • Persu, A.1    Lannoy, N.2    Maiter, D.3    Mendola, A.4    Montigny, P.5    Oriot, P.6    Vinck, W.7    Garin, P.8    Hamoir, M.9    Vikkula, M.10
  • 11
    • 84868621823 scopus 로고    scopus 로고
    • Treatment with sunitinib for patients with progressive metastatic pheochromocytomas and sympathetic paragangliomas
    • 22965939 10.1210/jc.2012-2356 1:CAS:528:DC%2BC38Xhs12ku77L Retrospective study that shows that sunitinib is associated with partial responses, blood pressure improvement, and decreased FDG-PET uptake, especially, in carriers of SDHB mutations
    • •• Ayala-Ramirez M, Chougnet CN, Habra MA, Palmer JL, Leboulleux S, Cabanillas ME, et al. Treatment with sunitinib for patients with progressive metastatic pheochromocytomas and sympathetic paragangliomas. J Clin Endocrinol Metab. 2012;97(11):4040-50. Retrospective study that shows that sunitinib is associated with partial responses, blood pressure improvement, and decreased FDG-PET uptake, especially, in carriers of SDHB mutations.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.11 , pp. 4040-4050
    • Ayala-Ramirez, M.1    Chougnet, C.N.2    Habra, M.A.3    Palmer, J.L.4    Leboulleux, S.5    Cabanillas, M.E.6    Caramella, C.7    Anderson, P.8    Al Ghuzlan, A.9    Waguespack, S.G.10
  • 12
  • 13
    • 77952777089 scopus 로고    scopus 로고
    • A current review of the etiology, diagnosis, and treatment of pediatric pheochromocytoma and paraganglioma
    • 20215394 10.1210/jc.2009-2830 1:CAS:528:DC%2BC3cXmtFegtLc%3D
    • Waguespack SG, Rich T, Grubbs E, Ying AK, Perrier ND, Ayala-Ramirez M, et al. A current review of the etiology, diagnosis, and treatment of pediatric pheochromocytoma and paraganglioma. J Clin Endocrinol Metab. 2010;95(5):2023-37.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.5 , pp. 2023-2037
    • Waguespack, S.G.1    Rich, T.2    Grubbs, E.3    Ying, A.K.4    Perrier, N.D.5    Ayala-Ramirez, M.6    Jimenez, C.7
  • 22
    • 28544446058 scopus 로고    scopus 로고
    • Mitochondrial tumour suppressors: A genetic and biochemical update
    • DOI 10.1038/nrc1737
    • Gottlieb E, Tomlinson IP. Mitochondrial tumour suppressors: A genetic and biochemical update. Nat Rev Cancer. 2005;5(11):857-66. (Pubitemid 41746030)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.11 , pp. 857-866
    • Gottlieb, E.1    Tomlinson, I.P.M.2
  • 25
    • 67651198212 scopus 로고    scopus 로고
    • An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: A retrospective and prospective analysis
    • 19576851 10.1016/S1470-2045(09)70164-0
    • van Nederveen FH, Gaal J, Favier J, Korpershoek E, Oldenburg RA, de Bruyn EM, et al. An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: A retrospective and prospective analysis. Lancet Oncol. 2009;10(8):764-71.
    • (2009) Lancet Oncol , vol.10 , Issue.8 , pp. 764-771
    • Van Nederveen, F.H.1    Gaal, J.2    Favier, J.3    Korpershoek, E.4    Oldenburg, R.A.5    De Bruyn, E.M.6    Sleddens, H.F.7    Derkx, P.8    Riviere, J.9    Dannenberg, H.10
  • 28
    • 84858703889 scopus 로고    scopus 로고
    • Long-term postoperative follow-up in patients with apparently benign pheochromocytoma and paraganglioma
    • 22351478 10.1055/s-0031-1301339 1:CAS:528:DC%2BC38XpvFKnt7s%3D
    • Amar L, Fassnacht M, Gimenez-Roqueplo AP, Januszewicz A, Prejbisz A, Timmers H, et al. Long-term postoperative follow-up in patients with apparently benign pheochromocytoma and paraganglioma. Horm Metab Res. 2012;44(5):385-9.
    • (2012) Horm Metab Res , vol.44 , Issue.5 , pp. 385-389
    • Amar, L.1    Fassnacht, M.2    Gimenez-Roqueplo, A.P.3    Januszewicz, A.4    Prejbisz, A.5    Timmers, H.6    Plouin, P.F.7
  • 30
    • 0033118548 scopus 로고    scopus 로고
    • Pheochromocytomas: Can malignant potential be predicted?
    • DOI 10.1016/S0090-4295(98)00612-8, PII S0090429598006128
    • John H, Ziegler WH, Hauri D, Jaeger P. Pheochromocytomas: Can malignant potential be predicted? Urology. 1999;53(4):679-83. (Pubitemid 29163029)
    • (1999) Urology , vol.53 , Issue.4 , pp. 679-683
    • John, H.1    Ziegler, W.H.2    Hauri, D.3    Jaeger, P.4
  • 31
  • 35
    • 66149083640 scopus 로고    scopus 로고
    • An unusual case of severe constipation due to metastatic pheochromocytoma
    • 19500719 10.1016/j.jpainsymman.2008.12.002
    • Mason LD, Prentice WM, Whitelaw BC. An unusual case of severe constipation due to metastatic pheochromocytoma. J Pain Symptom Manage. 2009;37(6):e5-7.
    • (2009) J Pain Symptom Manage , vol.37 , Issue.6 , pp. 5-7
    • Mason, L.D.1    Prentice, W.M.2    Whitelaw, B.C.3
  • 36
    • 58249095062 scopus 로고    scopus 로고
    • Metastases but not cardiovascular mortality reduces life expectancy following surgical resection of apparently benign pheochromocytoma
    • 18824558 10.1677/ERC-08-0049 1:STN:280:DC%2BD1M%2Fos1yktg%3D%3D
    • Timmers HJ, Brouwers FM, Hermus AR, Sweep FC, Verhofstad AA, Verbeek AL, et al. Metastases but not cardiovascular mortality reduces life expectancy following surgical resection of apparently benign pheochromocytoma. Endocr Relat Cancer. 2008;15(4):1127-33.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.4 , pp. 1127-1133
    • Timmers, H.J.1    Brouwers, F.M.2    Hermus, A.R.3    Sweep, F.C.4    Verhofstad, A.A.5    Verbeek, A.L.6    Pacak, K.7    Lenders, J.W.8
  • 37
    • 84876259718 scopus 로고    scopus 로고
    • Bone Metastases and Skeletal-Related Events in Patients with Malignant Pheochromocytoma and Sympathetic Paraganglioma
    • Systemic therapy and antiresortives may prevent skeletal related events in patients with malignant PHs and SPGs
    • • Ayala-Ramirez M, Palmer JL, Hoffman MC, de la Cruz M, Moon BS, Waguespack SG, Habra MA, Jimenez C: Bone Metastases and Skeletal-Related Events in Patients with Malignant Pheochromocytoma and Sympathetic Paraganglioma. J Clin Endocrinol Metab 2013. Systemic therapy and antiresortives may prevent skeletal related events in patients with malignant PHs and SPGs.
    • (2013) J Clin Endocrinol Metab
    • Ayala-Ramirez, M.1    Palmer, J.L.2    Hoffman, M.C.3    De La Cruz, M.4    Moon, B.S.5    Waguespack, S.G.6    Habra, M.A.7    Jimenez, C.8
  • 39
    • 34250159501 scopus 로고    scopus 로고
    • Superiority of fluorodeoxyglucose positron emission tomography to other functional imaging techniques in the evaluation of metastatic SDHB-associated pheochromocytoma and paraganglioma
    • DOI 10.1200/JCO.2006.09.6297
    • Timmers HJ, Kozupa A, Chen CC, Carrasquillo JA, Ling A, Eisenhofer G, et al. Superiority of fluorodeoxyglucose positron emission tomography to other functional imaging techniques in the evaluation of metastatic SDHB-associated pheochromocytoma and paraganglioma. J Clin Oncol. 2007;25(16):2262-9. (Pubitemid 46954653)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.16 , pp. 2262-2269
    • Timmers, H.J.L.M.1    Kozupa, A.2    Chen, C.C.3    Carrasquillo, J.A.4    Ling, A.5    Eisenhofer, G.6    Adams, K.T.7    Solis, D.8    Lenders, J.W.M.9    Pacak, K.10
  • 41
    • 45549098010 scopus 로고    scopus 로고
    • Current progress and future challenges in the biochemical diagnosis and treatment of pheochromocytomas and paragangliomas
    • DOI 10.1055/s-2008-1073156, Endocrine-related Tumors
    • Eisenhofer G, Siegert G, Kotzerke J, Bornstein SR, Pacak K. Current progress and future challenges in the biochemical diagnosis and treatment of pheochromocytomas and paragangliomas. Horm Metab Res. 2008;40(5):329-37. (Pubitemid 351859444)
    • (2008) Hormone and Metabolic Research , vol.40 , Issue.5 , pp. 329-337
    • Eisenhofer, G.1    Siegert, G.2    Kotzerke, J.3    Bornstein, S.R.4    Pacak, K.5
  • 42
    • 44349129164 scopus 로고    scopus 로고
    • Use of plasma chromogranin A and urine fractionated metanephrines to diagnose pheochromocytoma?
    • 18398404
    • Plouin PF. Use of plasma chromogranin A and urine fractionated metanephrines to diagnose pheochromocytoma? Nat Clin Pract Endocrinol Metab. 2008;4(6):314-5.
    • (2008) Nat Clin Pract Endocrinol Metab , vol.4 , Issue.6 , pp. 314-315
    • Plouin, P.F.1
  • 43
    • 0033670227 scopus 로고    scopus 로고
    • Malignant pheochromocytoma. Chromaffin granule transmitters and response to treatment
    • 11116123 10.1161/01.HYP.36.6.1045 1:CAS:528:DC%2BD3MXitlSguw%3D%3D
    • Rao F, Keiser HR, O'Connor DT. Malignant pheochromocytoma. Chromaffin granule transmitters and response to treatment. Hypertension. 2000;36(6):1045-52.
    • (2000) Hypertension , vol.36 , Issue.6 , pp. 1045-1052
    • Rao, F.1    Keiser, H.R.2    O'Connor, D.T.3
  • 44
    • 73249127006 scopus 로고    scopus 로고
    • Comparison of 18F-fluoro-L-DOPA, 18F-fluoro-deoxyglucose, and 18F-fluorodopamine PET and 123I-MIBG scintigraphy in the localization of pheochromocytoma and paraganglioma
    • 19864450 10.1210/jc.2009-1248 1:CAS:528:DC%2BD1MXhsFyltLbJ
    • Timmers HJ, Chen CC, Carrasquillo JA, Whatley M, Ling A, Havekes B, et al. Comparison of 18F-fluoro-L-DOPA, 18F-fluoro-deoxyglucose, and 18F-fluorodopamine PET and 123I-MIBG scintigraphy in the localization of pheochromocytoma and paraganglioma. J Clin Endocrinol Metab. 2009;94(12):4757-67.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.12 , pp. 4757-4767
    • Timmers, H.J.1    Chen, C.C.2    Carrasquillo, J.A.3    Whatley, M.4    Ling, A.5    Havekes, B.6    Eisenhofer, G.7    Martiniova, L.8    Adams, K.T.9    Pacak, K.10
  • 45
    • 35948976628 scopus 로고    scopus 로고
    • The diagnosis and management of malignant phaeochromocytoma and paraganglioma
    • DOI 10.1677/ERC-07-0074
    • Chrisoulidou A, Kaltsas G, Ilias I, Grossman AB. The diagnosis and management of malignant phaeochromocytoma and paraganglioma. Endocr Relat Cancer. 2007;14(3):569-85. (Pubitemid 350074048)
    • (2007) Endocrine-Related Cancer , vol.14 , Issue.3 , pp. 569-585
    • Chrisoulidou, A.1    Kaltsas, G.2    Ilias, I.3    Grossman, A.B.4
  • 48
    • 0034136190 scopus 로고    scopus 로고
    • Surgical excision of malignant pheochromocytoma in the left atrium
    • 10769996 10.1007/BF03218106 1:STN:280:DC%2BD3c3jt1ylsw%3D%3D
    • Nonaka K, Makuuchi H, Naruse Y, Kobayashi T, Goto M. Surgical excision of malignant pheochromocytoma in the left atrium. Jpn J Thorac Cardiovasc Surg. 2000;48(2):126-8.
    • (2000) Jpn J Thorac Cardiovasc Surg , vol.48 , Issue.2 , pp. 126-128
    • Nonaka, K.1    Makuuchi, H.2    Naruse, Y.3    Kobayashi, T.4    Goto, M.5
  • 49
    • 33845491965 scopus 로고    scopus 로고
    • Management and treatment of pheochromocytomas and paragangliomas
    • DOI 10.1196/annals.1353.044, Pheochromocytoma: First International Symposium
    • Mannelli M. Management and treatment of pheochromocytomas and paragangliomas. Ann N Y Acad Sci. 2006;1073:405-16. (Pubitemid 44912035)
    • (2006) Annals of the New York Academy of Sciences , vol.1073 , pp. 405-416
    • Mannelli, M.1
  • 50
    • 35648945390 scopus 로고    scopus 로고
    • Adverse drug reactions in patients with phaeochromocytoma: Incidence, prevention and management
    • Eisenhofer G, Rivers G, Rosas AL, Quezado Z, Manger WM, Pacak K. Adverse drug reactions in patients with phaeochromocytoma: Incidence, prevention and management. Drug Saf. 2007;30(11):1031-62. (Pubitemid 350036603)
    • (2007) Drug Safety , vol.30 , Issue.11 , pp. 1031-1062
    • Eisenhofer, G.1    Rivers, G.2    Rosas, A.L.3    Quezado, Z.4    Manger, W.M.5    Pacak, K.6
  • 51
    • 0036197738 scopus 로고    scopus 로고
    • I-123 MIBG imaging and intraoperative localization of metastatic pheochromocytoma a case report
    • DOI 10.1097/00003072-200203000-00007
    • Buhl T, Mortensen J, Kjaer A. I-123 MIBG imaging and intraoperative localization of metastatic pheochromocytoma: A case report. Clin Nucl Med. 2002;27(3):183-5. (Pubitemid 34195230)
    • (2002) Clinical Nuclear Medicine , vol.27 , Issue.3 , pp. 183-185
    • Buhl, T.1    Mortensen, J.2    Kjaer, A.3
  • 52
    • 0026597488 scopus 로고
    • Extra-adrenal pheochromocytoma
    • 1729490 1:STN:280:DyaK387gs1emtw%3D%3D
    • Whalen RK, Althausen AF, Daniels GH. Extra-adrenal pheochromocytoma. J Urol. 1992;147(1):1-10.
    • (1992) J Urol , vol.147 , Issue.1 , pp. 1-10
    • Whalen, R.K.1    Althausen, A.F.2    Daniels, G.H.3
  • 53
    • 80051975164 scopus 로고    scopus 로고
    • Minimally invasive treatment of metastatic pheochromocytoma and paraganglioma: Efficacy and safety of radiofrequency ablation and cryoablation therapy
    • 21856504 10.1016/j.jvir.2011.06.016
    • McBride JF, Atwell TD, Charboneau WJ, Young Jr WF, Wass TC, Callstrom MR. Minimally invasive treatment of metastatic pheochromocytoma and paraganglioma: Efficacy and safety of radiofrequency ablation and cryoablation therapy. J Vasc Interv Radiol. 2011;22(9):1263-70.
    • (2011) J Vasc Interv Radiol , vol.22 , Issue.9 , pp. 1263-1270
    • McBride, J.F.1    Atwell, T.D.2    Charboneau, W.J.3    Young, Jr.W.F.4    Wass, T.C.5    Callstrom, M.R.6
  • 54
    • 0014830747 scopus 로고
    • The management of ectopic pheochromocytoma producing ureteral obstruction
    • 5448911 1:STN:280:DyaE3c3lvVWhsw%3D%3D
    • Immergut MA, Boldus R, Kollin CP, Rohlf P. The management of ectopic pheochromocytoma producing ureteral obstruction. J Urol. 1970;104(2):337-41.
    • (1970) J Urol , vol.104 , Issue.2 , pp. 337-341
    • Immergut, M.A.1    Boldus, R.2    Kollin, C.P.3    Rohlf, P.4
  • 55
    • 0014155094 scopus 로고
    • The concentration of radioactivity from labeled epinephrine and its precursors in the dog adrenal medulla
    • 6061766 1:STN:280:DyaF1c%2FlsFGntA%3D%3D
    • Morales JO, Beierwaltes WH, Counsell RE, Meier DH. The concentration of radioactivity from labeled epinephrine and its precursors in the dog adrenal medulla. J Nucl Med. 1967;8(11):800-9.
    • (1967) J Nucl Med , vol.8 , Issue.11 , pp. 800-809
    • Morales, J.O.1    Beierwaltes, W.H.2    Counsell, R.E.3    Meier, D.H.4
  • 56
    • 0017861709 scopus 로고
    • Adrenal imaging agents: rationale, synthesis, formulation and, metabolism
    • Beierwaltes WH, Wieland DM, Yu T, Swanson DP, Mosley ST. Adrenal imaging agents: Rationale, synthesis, formulation and, metabolism. Semin Nucl Med. 1978;8(1):5-21. (Pubitemid 8282217)
    • (1978) Seminars in Nuclear Medicine , vol.8 , Issue.1 , pp. 5-21
    • Beierwaltes, W.H.1    Wieland, D.M.2    Yu, T.3
  • 57
    • 0014472486 scopus 로고
    • Labeled dopamine concentration in human adrenal medulla and in neuroblastoma
    • 4306580 1:CAS:528:DyaF1MXms1ahtQ%3D%3D
    • Lieberman LM, Beierwaltes WH, Varma VM, Weinhold P, Ling R. Labeled dopamine concentration in human adrenal medulla and in neuroblastoma. J Nucl Med. 1969;10(2):93-7.
    • (1969) J Nucl Med , vol.10 , Issue.2 , pp. 93-97
    • Lieberman, L.M.1    Beierwaltes, W.H.2    Varma, V.M.3    Weinhold, P.4    Ling, R.5
  • 60
    • 0018908664 scopus 로고
    • 131I]iodobenzylguanidine
    • Wieland DM, Wu J, Brown LE, Mangner TJ, Swanson DP, Beierwaltes WH. Radiolabeled adrenergi neuron-blocking agents: Adrenomedullary imaging with [131I]iodobenzylguanidine. J Nucl Med. 1980;21(4):349-53. (Pubitemid 10100562)
    • (1980) Journal of Nuclear Medicine , vol.21 , Issue.4 , pp. 349-353
    • Wieland, D.M.1    Wu, J.I.2    Brown, L.E.3
  • 61
    • 0021340005 scopus 로고
    • Radiopharmaceutical treatment of malignant pheochromocytoma
    • Sisson JC, Shapiro B, Beierwaltes WH, Glowniak JV, Nakajo M, Mangner TJ, et al. Radiopharmaceutical treatment of malignant pheochromocytoma. J Nucl Med. 1984;25(2):197-206. (Pubitemid 14187477)
    • (1984) Journal of Nuclear Medicine , vol.25 , Issue.2 , pp. 197-206
    • Sisson, J.C.1    Shapiro, B.2    Beierwaltes, W.H.3
  • 63
    • 70249133742 scopus 로고    scopus 로고
    • Phase II study of high-dose [131I]metaiodobenzylguanidine therapy for patients with metastatic pheochromocytoma and paraganglioma
    • 19636009 10.1200/JCO.2008.21.3496 1:CAS:528:DC%2BD1MXhtF2jtLrJ To date, this is the only published phase 2 clinical trial against metastatic PH and SPG; this study describes the clinical benefits derived from MIBG therapy
    • • Gonias S, Goldsby R, Matthay KK, Hawkins R, Price D, Huberty J, et al. Phase II study of high-dose [131I]metaiodobenzylguanidine therapy for patients with metastatic pheochromocytoma and paraganglioma. J Clin Oncol. 2009;27(25):4162-8. To date, this is the only published phase 2 clinical trial against metastatic PH and SPG; this study describes the clinical benefits derived from MIBG therapy.
    • (2009) J Clin Oncol , vol.27 , Issue.25 , pp. 4162-4168
    • Gonias, S.1    Goldsby, R.2    Matthay, K.K.3    Hawkins, R.4    Price, D.5    Huberty, J.6    Damon, L.7    Linker, C.8    Sznewajs, A.9    Shiboski, S.10
  • 64
    • 84858797288 scopus 로고    scopus 로고
    • Radionuclide therapy in neuroendocrine tumours: A systematic review
    • 10.1016/j.clon.2011.12.003 1:STN:280:DC%2BC38zpvValug%3D%3D
    • Gulenchyn KY, Yao X, Asa SL, Singh S, Law C. Radionuclide therapy in neuroendocrine tumours: A systematic review. Clin Oncol (R Coll Radiol). 2012;24(4):294-308.
    • (2012) Clin Oncol (R Coll Radiol) , vol.24 , Issue.4 , pp. 294-308
    • Gulenchyn, K.Y.1    Yao, X.2    Asa, S.L.3    Singh, S.4    Law, C.5
  • 68
    • 0021808684 scopus 로고
    • Treatment of malignant pheochromocytoma with combination chemotherapy
    • Keiser HR, Goldstein DS, Wade JL, Douglas FL, Averbuch SD. Treatment of malignant pheochromocytoma with combination chemotherapy. Hypertension. 1985;7(3 Pt 2):I18-24. (Pubitemid 15005755)
    • (1985) Hypertension , vol.7 , Issue.SUPPL. 1 , pp. 18-24
    • Keiser, H.R.1    Goldstein, D.S.2    Wade, J.L.3
  • 69
    • 0023789889 scopus 로고
    • Malignant pheochromocytoma: Effective treatment with a combination of cyclophosphamide, vincristine, and dacarbazine
    • 3395037 10.7326/0003-4819-109-4-267 1:STN:280:DyaL1c3otVSgtw%3D%3D
    • Averbuch SD, Steakley CS, Young RC, Gelmann EP, Goldstein DS, Stull R, et al. Malignant pheochromocytoma: Effective treatment with a combination of cyclophosphamide, vincristine, and dacarbazine. Ann Intern Med. 1988;109(4):267-73.
    • (1988) Ann Intern Med , vol.109 , Issue.4 , pp. 267-273
    • Averbuch, S.D.1    Steakley, C.S.2    Young, R.C.3    Gelmann, E.P.4    Goldstein, D.S.5    Stull, R.6    Keiser, H.R.7
  • 70
    • 55749091604 scopus 로고    scopus 로고
    • Treatment of malignant pheochromocytoma/paraganglioma with cyclophosphamide, vincristine, and dacarbazine: Recommendation from a 22-year follow-up of 18 patients
    • 18780317 10.1002/cncr.23812 1:CAS:528:DC%2BD1cXht12lurfK
    • Huang H, Abraham J, Hung E, Averbuch S, Merino M, Steinberg SM, et al. Treatment of malignant pheochromocytoma/paraganglioma with cyclophosphamide, vincristine, and dacarbazine: Recommendation from a 22-year follow-up of 18 patients. Cancer. 2008;113(8):2020-8.
    • (2008) Cancer , vol.113 , Issue.8 , pp. 2020-2028
    • Huang, H.1    Abraham, J.2    Hung, E.3    Averbuch, S.4    Merino, M.5    Steinberg, S.M.6    Pacak, K.7    Fojo, T.8
  • 71
    • 0029122490 scopus 로고
    • A 15-year experience with chemotherapy of patients with paraganglioma
    • 8620426 10.1002/1097-0142(19951015)76:8<1476: AID-CNCR2820760827>3. 0.CO;2-9 1:STN:280:DyaK283itlajtg%3D%3D
    • Patel SR, Winchester DJ, Benjamin RS. A 15-year experience with chemotherapy of patients with paraganglioma. Cancer. 1995;76(8):1476-80.
    • (1995) Cancer , vol.76 , Issue.8 , pp. 1476-1480
    • Patel, S.R.1    Winchester, D.J.2    Benjamin, R.S.3
  • 72
    • 84874410063 scopus 로고    scopus 로고
    • Combination chemotherapy with cyclophosphamide, vincristine, and dacarbazine in patients with malignant pheochromocytoma and paraganglioma
    • 23361939 10.1007/s12672-013-0133-2 1:CAS:528:DC%2BC3sXjt1Wlt74%3D
    • Tanabe A, Naruse M, Nomura K, Tsuiki M, Tsumagari A, Ichihara A. Combination chemotherapy with cyclophosphamide, vincristine, and dacarbazine in patients with malignant pheochromocytoma and paraganglioma. Horm Cancer. 2013;4(2):103-10.
    • (2013) Horm Cancer , vol.4 , Issue.2 , pp. 103-110
    • Tanabe, A.1    Naruse, M.2    Nomura, K.3    Tsuiki, M.4    Tsumagari, A.5    Ichihara, A.6
  • 73
    • 84861329707 scopus 로고    scopus 로고
    • Clinical benefits of systemic chemotherapy for patients with metastatic pheochromocytomas or sympathetic extra-adrenal paragangliomas: Insights from the largest single-institutional experience
    • 22006217 10.1002/cncr.26577 1:CAS:528:DC%2BC38Xnt1Kgtb8%3D First study that shows that a positive response to chemotherapy is associated with a longer overall survival
    • • Ayala-Ramirez M, Feng L, Habra MA, Rich T, Dickson PV, Perrier N, et al. Clinical benefits of systemic chemotherapy for patients with metastatic pheochromocytomas or sympathetic extra-adrenal paragangliomas: Insights from the largest single-institutional experience. Cancer. 2012;118(11):2804-12. First study that shows that a positive response to chemotherapy is associated with a longer overall survival.
    • (2012) Cancer , vol.118 , Issue.11 , pp. 2804-2812
    • Ayala-Ramirez, M.1    Feng, L.2    Habra, M.A.3    Rich, T.4    Dickson, P.V.5    Perrier, N.6    Phan, A.7    Waguespack, S.8    Patel, S.9    Jimenez, C.10
  • 74
    • 0025894816 scopus 로고
    • Case report of metastatic familial pheochromocytoma treated with cisplatin and 5-fluorouracil
    • 1855279 10.1007/BF00685513 1:STN:280:DyaK3MzgvFWrsw%3D%3D
    • Srimuninnimit V, Wampler GL. Case report of metastatic familial pheochromocytoma treated with cisplatin and 5-fluorouracil. Cancer Chemother Pharmacol. 1991;28(3):217-9.
    • (1991) Cancer Chemother Pharmacol , vol.28 , Issue.3 , pp. 217-219
    • Srimuninnimit, V.1    Wampler, G.L.2
  • 75
    • 79954484756 scopus 로고    scopus 로고
    • Changing paradigms in the treatment of malignant pheochromocytoma
    • 21451453
    • Grogan RH, Mitmaker EJ, Duh QY. Changing paradigms in the treatment of malignant pheochromocytoma. Cancer Control. 2011;18(2):104-12.
    • (2011) Cancer Control , vol.18 , Issue.2 , pp. 104-112
    • Grogan, R.H.1    Mitmaker, E.J.2    Duh, Q.Y.3
  • 76
    • 0015596296 scopus 로고
    • Prolonged survival in malignant pheochromocytoma of the organ of Zuckerkandl with pharmacological treatment
    • 4693602 10.1002/1097-0142(197303)31:3<746: AID-CNCR2820310339>3.0. CO;2-1 1:STN:280:DyaE3s7ksFGqtA%3D%3D
    • Scharf Y, Nahir AM, Better OS, Koten A, Arieh YB, Gellei B. Prolonged survival in malignant pheochromocytoma of the organ of Zuckerkandl with pharmacological treatment. Cancer. 1973;31(3):746-50.
    • (1973) Cancer , vol.31 , Issue.3 , pp. 746-750
    • Scharf, Y.1    Nahir, A.M.2    Better, O.S.3    Koten, A.4    Arieh, Y.B.5    Gellei, B.6
  • 78
    • 0020588990 scopus 로고
    • Treatment of metastatic pheochromocytoma with streptozocin
    • DOI 10.1001/archinte.143.9.1799
    • Feldman JM. Treatment of metastatic pheochromocytoma with streptozocin. Arch Intern Med. 1983;143(9):1799-800. (Pubitemid 13007166)
    • (1983) Archives of Internal Medicine , vol.143 , Issue.9 , pp. 1799-1800
    • Feldman, J.M.1
  • 80
    • 0035213138 scopus 로고    scopus 로고
    • The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway
    • DOI 10.1086/324413
    • Gimenez-Roqueplo AP, Favier J, Rustin P, Mourad JJ, Plouin PF, Corvol P, et al. The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway. Am J Hum Genet. 2001;69(6):1186-97. (Pubitemid 33124200)
    • (2001) American Journal of Human Genetics , vol.69 , Issue.6 , pp. 1186-1197
    • Gimenez-Roqueplo, A.-P.1    Favier, J.2    Rustin, P.3    Mourad, J.-J.4    Plouin, P.-F.5    Corvol, P.6    Rotig, A.7    Jeunemaitre, X.8
  • 82
    • 0036792605 scopus 로고    scopus 로고
    • Angiogenesis and vascular architecture in pheochromocytomas: Distinctive traits in malignant tumors
    • 12368197 10.1016/S0002-9440(10)64400-8 1:CAS:528:DC%2BD38Xotl2jsr8%3D
    • Favier J, Plouin PF, Corvol P, Gasc JM. Angiogenesis and vascular architecture in pheochromocytomas: Distinctive traits in malignant tumors. Am J Pathol. 2002;161(4):1235-46.
    • (2002) Am J Pathol , vol.161 , Issue.4 , pp. 1235-1246
    • Favier, J.1    Plouin, P.F.2    Corvol, P.3    Gasc, J.M.4
  • 83
    • 0038378745 scopus 로고    scopus 로고
    • VEGF in 105 pheochromocytomas: Enhanced expression correlates with malignant outcome
    • DOI 10.1034/j.1600-0463.2003.1110402.x
    • Salmenkivi K, Heikkila P, Liu J, Haglund C, Arola J. VEGF in 105 pheochromocytomas: enhanced expression correlates with malignant outcome. APMIS. 2003;111(4):458-64. (Pubitemid 36735003)
    • (2003) APMIS , vol.111 , Issue.4 , pp. 458-464
    • Salmenkivi, K.1    Heikkila, P.2    Liu, J.3    Haglund, C.4    Arola, J.5
  • 84
    • 0344196771 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and its cognate receptors in human pheochromocytomas
    • DOI 10.1016/j.lfs.2003.07.036
    • Takekoshi K, Isobe K, Yashiro T, Hara H, Ishii K, Kawakami Y, et al. Expression of vascular endothelial growth factor (VEGF) and its cognate receptors in human pheochromocytomas. Life Sci. 2004;74(7):863-71. (Pubitemid 37501135)
    • (2004) Life Sciences , vol.74 , Issue.7 , pp. 863-871
    • Takekoshi, K.1    Isobe, K.2    Yashiro, T.3    Hara, H.4    Ishii, K.5    Kawakami, Y.6    Nakai, T.7    Okuda, Y.8
  • 85
    • 20944451025 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression, vascularization and proliferation in paragangliomas
    • DOI 10.1159/000085171
    • Brieger J, Bedavanija A, Gosepath J, Maurer J, Mann WJ. Vascular endothelial growth factor expression, vascularization and proliferation in paragangliomas. ORL J Otorhinolaryngol Relat Spec. 2005;67(2):119-24. (Pubitemid 40868748)
    • (2005) ORL , vol.67 , Issue.2 , pp. 119-124
    • Brieger, J.1    Bedavanija, A.2    Gosepath, J.3    Maurer, J.4    Mann, W.J.5
  • 88
    • 58149385799 scopus 로고    scopus 로고
    • Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/pheochromocytoma
    • 19001511 10.1210/jc.2008-1836 1:CAS:528:DC%2BD1MXptVKnuw%3D%3D
    • Joshua AM, Ezzat S, Asa SL, Evans A, Broom R, Freeman M, et al. Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/ pheochromocytoma. J Clin Endocrinol Metab. 2009;94(1):5-9.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.1 , pp. 5-9
    • Joshua, A.M.1    Ezzat, S.2    Asa, S.L.3    Evans, A.4    Broom, R.5    Freeman, M.6    Knox, J.J.7
  • 89
    • 59749100013 scopus 로고    scopus 로고
    • Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: Targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors
    • 19017755 10.1210/jc.2008-1972 1:CAS:528:DC%2BD1MXhvFCqs7s%3D
    • Jimenez C, Cabanillas ME, Santarpia L, Jonasch E, Kyle KL, Lano EA, et al. Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors. J Clin Endocrinol Metab. 2009;94(2):386-91.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.2 , pp. 386-391
    • Jimenez, C.1    Cabanillas, M.E.2    Santarpia, L.3    Jonasch, E.4    Kyle, K.L.5    Lano, E.A.6    Matin, S.F.7    Nunez, R.F.8    Perrier, N.D.9    Phan, A.10
  • 91
    • 77952883699 scopus 로고    scopus 로고
    • Update on systemic therapies of metastatic renal cell carcinoma
    • 20180125 10.1007/s00345-010-0519-5 1:CAS:528:DC%2BC3cXmtlynsb8%3D
    • Herrmann E, Bierer S, Wulfing C. Update on systemic therapies of metastatic renal cell carcinoma. World J Urol. 2010;28(3):303-9.
    • (2010) World J Urol , vol.28 , Issue.3 , pp. 303-309
    • Herrmann, E.1    Bierer, S.2    Wulfing, C.3
  • 92
    • 84870004468 scopus 로고    scopus 로고
    • Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma
    • 22962301 10.1093/hmg/dds374 1:CAS:528:DC%2BC38XhvVSmtL3E Somatic NF1 mutations are present in some sporadic malignant PHs and SPGs; mTOR and MEK inhibitors might be explored in clinical trials against metastatic disease
    • • Burnichon N, Buffet A, Parfait B, Letouze E, Laurendeau I, Loriot C, et al. Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma. Hum Mol Genet. 2012;21(26):5397-405. Somatic NF1 mutations are present in some sporadic malignant PHs and SPGs; mTOR and MEK inhibitors might be explored in clinical trials against metastatic disease.
    • (2012) Hum Mol Genet , vol.21 , Issue.26 , pp. 5397-5405
    • Burnichon, N.1    Buffet, A.2    Parfait, B.3    Letouze, E.4    Laurendeau, I.5    Loriot, C.6    Pasmant, E.7    Abermil, N.8    Valeyrie-Allanore, L.9    Bertherat, J.10
  • 93
    • 33751162384 scopus 로고    scopus 로고
    • Therapeutic targets: MTOR and related pathways
    • Dancey JE. Therapeutic targets: MTOR and related pathways. Cancer Biol Ther. 2006;5(9):1065-73. (Pubitemid 44773684)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.9 , pp. 1065-1073
    • Dancey, J.E.1
  • 94
    • 70350354684 scopus 로고    scopus 로고
    • Novel and evolving therapies in the treatment of malignant phaeochromocytoma: Experience with the mTOR inhibitor everolimus (RAD001)
    • 19424940 10.1055/s-0029-1220687 1:CAS:528:DC%2BD1MXhtlalt7%2FJ
    • Druce MR, Kaltsas GA, Fraenkel M, Gross DJ, Grossman AB. Novel and evolving therapies in the treatment of malignant phaeochromocytoma: Experience with the mTOR inhibitor everolimus (RAD001). Horm Metab Res. 2009;41(9):697-702.
    • (2009) Horm Metab Res , vol.41 , Issue.9 , pp. 697-702
    • Druce, M.R.1    Kaltsas, G.A.2    Fraenkel, M.3    Gross, D.J.4    Grossman, A.B.5
  • 95
    • 84870679939 scopus 로고    scopus 로고
    • Phase 2 study of everolimus monotherapy in patients with nonfunctioning neuroendocrine tumors or pheochromocytomas/paragangliomas
    • 22736481 10.1002/cncr.27675 1:CAS:528:DC%2BC38XhslKrur7I
    • Oh DY, Kim TW, Park YS, Shin SJ, Shin SH, Song EK, et al. Phase 2 study of everolimus monotherapy in patients with nonfunctioning neuroendocrine tumors or pheochromocytomas/paragangliomas. Cancer. 2012;118(24):6162-70.
    • (2012) Cancer , vol.118 , Issue.24 , pp. 6162-6170
    • Oh, D.Y.1    Kim, T.W.2    Park, Y.S.3    Shin, S.J.4    Shin, S.H.5    Song, E.K.6    Lee, H.J.7    Lee, K.W.8    Bang, Y.J.9
  • 96
    • 33750483896 scopus 로고    scopus 로고
    • The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: Enhancement of growth inhibition via inhibition of mammalian target of rapamcycin signaling
    • DOI 10.1158/1535-7163.MCT-06-0071
    • Ikezoe T, Nishioka C, Tasaka T, Yang Y, Komatsu N, Togitani K, et al. The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling. Mol Cancer Ther. 2006;5(10):2522-30. (Pubitemid 44650916)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.10 , pp. 2522-2530
    • Ikezoe, T.1    Nishioka, C.2    Tasaka, T.3    Yang, Y.4    Komatsu, N.5    Togitani, K.6    Koeffler, H.P.7    Taguchi, H.8
  • 99
    • 70350408500 scopus 로고    scopus 로고
    • Malignant pheochromocytomas and paragangliomas: Molecular signaling pathways and emerging therapies
    • 19343618 10.1055/s-0029-1214381 1:CAS:528:DC%2BD1MXhtlalt7%2FP
    • Santarpia L, Habra MA, Jimenez C. Malignant pheochromocytomas and paragangliomas: Molecular signaling pathways and emerging therapies. Horm Metab Res. 2009;41(9):680-6.
    • (2009) Horm Metab Res , vol.41 , Issue.9 , pp. 680-686
    • Santarpia, L.1    Habra, M.A.2    Jimenez, C.3


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