Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Sanchez Romero, Inmaculada ^a,d   Ariza, Antonio ^b,e   Wilson, Keith S ^b   Skjøt, Michael ^c,f   Vind, Jesper ^c   de Maria, Leonardo ^c   Skov, Lars K ^c   Sanchez Ruiz, Jose M ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF YORK   (United Kingdom)

^c NOVOZYMES A S   (Denmark)

^d INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

^e UNIVERSITY OF LEEDS   (United Kingdom)

^f NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

PHYTASE;

ARTICLE; CITROBACTER; CITROBACTER BRAAKII; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DISULFIDE BOND; ENZYME KINETICS; HIGH TEMPERATURE; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN DENATURATION; PROTEIN STABILITY; PROTEIN UNFOLDING; REGULATORY MECHANISM; TEMPERATURE DEPENDENCE; THERMODYNAMICS; THERMOSTABILITY;

6-PHYTASE; CITROBACTER; DISULFIDES; ENZYME ACTIVATION; ENZYME STABILITY; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN ENGINEERING; PROTEIN FOLDING; TEMPERATURE; THERMODYNAMICS;

EID: 84880777729     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070013     Document Type: Article

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