A Proline-Hinge Alters the Characteristics of the Amphipathic α-helical AMPs

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Lee, Jong Kook ^a   Gopal, Ramamourthy ^a   Park, Seong Cheol ^a   Ko, Hyun Sook ^b   Kim, Yangmee ^b   Hahm, Kyung Soo ^a,c   Park, Yoonkyung ^a  

^a Chosun University   (South Korea)

^b Konkuk University   (South Korea)

^c Bioleaders Corporation   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANAL 3; ANAL 3 PRO; BUFORIN 2; DODECYL SULFATE SODIUM; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GLUTAMINE; MAGAININ 2; POLYPEPTIDE ANTIBIOTIC AGENT; PROLINE; TRIFLUOROETHANOL; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; CANDIDA ALBICANS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; FUNGAL MEMBRANE; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE ANALYSIS; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; CANDIDA ALBICANS; CELL MEMBRANE PERMEABILITY; CHITIN; CHOLESTEROL; CIRCULAR DICHROISM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; HEMOLYSIS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PEPTIDOGLYCAN; PHOSPHATIDYLCHOLINES; PROLINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; UNILAMELLAR LIPOSOMES;

EID: 84880751395     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067597     Document Type: Article

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