FX enzyme and GDP-L-Fuc transporter expression in colorectal cancer

Histopathology

Volumn 63, Issue 2, 2013, Pages 174-186

  Villar Portela, Susana ^a   Muinelo Romay, Laura ^b   Cuevas, Elisa ^c   Gil Martín, Emilio ^a   Fernández Briera, Almudena ^a  

^a UNIVERSITY OF VIGO   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^c University Hospital Complex   (Spain)

Author keywords

(1,6)fucosylation; Colorectal cancer; FX; GDP Fuc Tr

Indexed keywords

FUCOSYLTRANSFERASE; GUANOSINE DIPHOSPHATE; GUANOSINE DIPHOSPHATE L FUCOSE; UNCLASSIFIED DRUG;

AGED; ARTICLE; CANCER PATIENT; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; FOLLOW UP; FUCOSYLATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84880714497     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/his.12157     Document Type: Article

References (32)

1. Hakomori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res. 1989; 52; 257-331.
2. Staudacher E, Altmann F, Wilson IB, März L. Fucose in N-glycans: from plant to man. Biochim. Biophys. Acta 1999; 1473; 216-236.
3. Miyoshi E, Moriwaki K, Nakagawa T. Biological function of fucosylation in cancer biology. J. Biochem. 2008; 143; 725-729.
4. Zhao Y, Sato Y, Isaji T et al. Branched N-glycans regulate the biological functions of integrins and cadherins. FEBS J. 2008; 275; 1939-1948.
5. Hutchinson WL, Du MQ, Johnson PJ, Williams R. Fucosyltransferases: differential plasma and tissue alterations in hepatocellular carcinoma and cirrhosis. Hepatology 1991; 13; 683-688.
6. Miyoshi E, Noda K, Ko JH et al. Overexpression of α1-6 fucosyltransferase in hepatoma cells suppresses intrahepatic metastasis after splenic injection in athymic mice. Cancer Res. 1999; 59; 2237-2243.
7. Takahashi T, Ikeda Y, Miyoshi E, Yaginuma Y, Ishikawa M, Taniguchi N. α1, 6Fucosyltransferase is highly and specifically expressed in human ovarian serous adenocarcinomas. Int. J. Cancer 2000; 88; 914-919.
8. Ito Y, Miyauchi A, Yoshida H et al. Expression of α1, 6-fucosyltransferase (FUT8) in papillary carcinoma of the thyroid: its linkage to biological aggressiveness and anaplastic transformation. Cancer Lett. 2003; 200; 167-172.
9. Muinelo-Romay L, Vázquez-Martín C, Villar-Portela S, Cuevas E, Gil-Martín E, Fernández-Briera A. Expression and enzyme activity of α(1, 6)fucosyltransferase in human colorectal cancer. Int. J. Cancer 2008; 123; 641-646.
10. Muinelo-Romay L, Villar-Portela S, Cuevas Alvarez E, Gil-Martín E, Fernández-Briera A. α(1, 6)Fucosyltransferase expression is an independent prognostic factor for disease-free survival in colorectal carcinoma. Hum. Pathol. 2011; 42; 1740-1750.
11. Becker DJ, Lowe JB. Fucose: biosynthesis and biological function in mammals. Glycobiology 2003; 13; 41-53.
12. Park SH, Pastuszak I, Drake R, Elbein AD. Purification to apparent homogeneity and properties of pig kidney L-fucose kinase. J. Biol. Chem. 1998; 273; 5685-5691.
13. Pastuszak I, Ketchum C, Hermanson G, Sjoberg EJ, Drake R, Elbein AD. GDP-L-fucose pyrophosphorylase. Purification, cDNA cloning, and properties of the enzyme. J. Biol. Chem. 1998; 273; 30165-30174.
14. Ohyama C, Smith PL, Angata K, Fukuda MN, Lowe JB, Fukuda M. Molecular cloning and expression of GDP-D-mannose-4, 6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells. J. Biol. Chem. 1998; 273; 14582-14587.
15. Sullivan FX, Kumar R, Kriz R et al. Molecular cloning of human GDP-mannose 4, 6-dehydratase and reconstitution of GDP-L-Fucose biosynthesis in vitro. J. Biol. Chem. 1998; 273; 8193-8202.
16. Tonetti M, Sturla L, Bisso A, Benatti U, De Flora A. Synthesis of GDP-L-fucose by the human FX protein. J. Biol. Chem. 1996; 271; 27274-27279.
17. Puglielli L, Hirschberg CB. Reconstitution, identification, and purification of the rat liver Golgi membrane GDP-fucose transporter. J. Biol. Chem. 1999; 274; 35596-35600.
18. Niittymäki J, Mattila P, Renkonen R. Differential gene expression of GDP-L-fucose-synthesizing enzymes, GDP-L-Fucose transporter and fucosyltransferase VII. APMIS 2006; 114; 539-548.
19. Noda K, Miyoshi E, Gu J et al. Relationship between elevated FX expression and increased production of GDP-L-fucose, a common donor substrate for fucosylation in human hepatocellular carcinoma and hepatoma cell lines. Cancer Res. 2003; 63; 6282-6289.
20. Moriwaki K, Noda K, Nakagawa T et al. A high expression of GDP-L-fucose transporter in hepatocellular carcinoma is a key factor for increases in fucosylation. Glycobiology 2007; 17; 1311-1320.
21. International Union Against Cancer (UICC). Digestive System Tumours. Colon and rectum. In Sobin LH, Wittekind C eds. TNM classification of malignant tumors. Digestive system tumours. Colon and rectum. 6th edn. New York: Wiley-Liss, 2002; 72-76.
22. Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J. Am. Stat. Assoc. 1958; 53; 457-481.
23. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother. Rep. 1966; 50; 163-170.
24. Cox DR. Regression models and life tables. J. R. Stat. Soc. Ser. B-Stat. Methodol. 1972; 34; 187-220.
25. Moriwaki K, Miyoshi E. Fucosylation and gastrointestinal cancer. World J. Hepatol. 2010; 2; 151-161.
26. Muinelo-Romay L, Villar-Portela S, Cuevas Alvarez E, Gil-Martín E, Fernández-Briera A. Identification of α(1, 6)fucosylated proteins differentially expressed in human colorectal cancer. BMC Cancer 2011; 11; 508.
27. Sturla L, Puglielli L, Tonetti M et al. Impairment of the Golgi GDP-L-fucose transport and unresponsiveness to fucose replacement therapy in LAD II patients. Pediatr. Res. 2001; 49; 537-542.
28. Kumamoto K, Goto Y, Sekikawa K et al. Increased expression of UDP-galactose transporter messenger RNA in human colon cancer tissues and its implication in synthesis of Thomsen-Friedenreich antigen and sialyl Lewis A/X determinants. Cancer Res. 2001; 61; 4620-4627.
29. Zipin A, Israeli-Amit M, Meshel T et al. Tumor-microenvironment interactions. The fucose-generating FX enzyme controls adhesive properties of colorectal cancer cells. Cancer Res. 2004; 64; 6571-6578.
30. a antigen. J. Biol. Chem. 1985; 260; 9388-9392.
31. x. Arch. Biochem. Biophys. 2004; 426; 122-131.
32. x expression in colorectal cancer: implications for tumorigenesis and disease prognosis. Histol. Histopathol. 2011; 26; 1305-1316.