Microtubule motors: A new hope for kinesin-5 inhibitors?

Current Biology

Volumn 23, Issue 14, 2013, Pages

  Groen, Aaron ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84880684448     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2013.05.049     Document Type: Short Survey

References (8)

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3. E.G. Sturgill, and R. Ohi Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate Curr. Biol. 23 2013 1280 1290
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5. M.E. Tanenbaum, L. Macurek, A. Janssen, E.F. Geers, M. Alvarez-Fernandez, and R.H. Medema Kif15 cooperates with eg5 to promote bipolar spindle assembly Curr. Biol. 19 2009 1703 1711
6. T. Wittmann, H. Boleti, C. Antony, E. Karsenti, and I. Vernos Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein J. Cell Biol. 143 1998 673 685
7. S. Petry, A.C. Groen, K. Ishihara, T.J. Mitchison, and R.D. Vale Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2 Cell 152 2013 768 777
8. R. Jones, J. Vuky, T. Elliott, G. Mead, J.A. Arranz, J. Chester, S. Chowdhury, A.Z. Dudek, V. Müller-Mattheis, and M.O. Grimm Phase II study to assess the efficacy, safety and tolerability of the mitotic spindle kinesin inhibitor AZD4877 in patients with recurrent advanced urothelial cancer Invest. New Drugs 2013 10.1007/s10637-013-9926-y