In Vivo Neutralization of α-Cobratoxin with High-Affinity Llama Single-Domain Antibodies (VHHs) and a VHH-Fc Antibody

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Richard, Gabrielle ^a,b   Meyers, Ashley J ^a   McLean, Michael D ^a   Arbabi Ghahroudi, Mehdi ^b   MacKenzie, Roger ^a,b   Hall, J Christopher ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COBROTOXIN; SINGLE VARIABLE DOMAIN ANTIBODY; SINGLE VARIABLE DOMAIN FC ANTIBODY; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG PENETRATION; ENVENOMATION; FEMALE; HUMORAL IMMUNITY; IN VIVO STUDY; LETHALITY; MALE; MOLECULAR WEIGHT; MOUSE; NICOTIANA BENTHAMIANA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODY AFFINITY; CAMELIDS, NEW WORLD; COBRA NEUROTOXIN PROTEINS; COBRA VENOMS; HALF-LIFE; HUMANS; IMMUNITY, HUMORAL; IMMUNIZATION; IMMUNOGLOBULIN FC FRAGMENTS; KINETICS; MALE; MICE; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; SINGLE-DOMAIN ANTIBODIES;

EID: 84880668688     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069495     Document Type: Article

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